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Scopus Author ID: 38662884100

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Employment (1)

Karolinska Institutet: Stockholm, SE

2015-09-01 to present | Projet leader (Department of Medical Biochemistry and Biophysics)
Employment
Source: Self-asserted source
Dimitrios Kanellis

Education and qualifications (3)

University of Crete School of Medicine & FORTH/IMBB: Heraklion, GR

2007 to 2014 | PhD Inflammation associated carcinogenesis
Education
Source: Self-asserted source
Dimitrios Kanellis

University of Crete School of Medicine: Heraklion, GR

2005 to 2007 | MSc - Molecular Basis of Human Diseases
Education
Source: Self-asserted source
Dimitrios Kanellis

Aristotle University of Thessaloniki: Thessaloniki, GR

2000-01-09 to 2005-04-04 | Ptychion (Biology)
Education
Source: Self-asserted source
Dimitrios Kanellis

Works (15)

Chromatin damage generated by DNA intercalators leads to degradation of RNA Polymerase II

Nucleic Acids Research
2024-05-08 | Journal article
DOI: 10.1093/nar/gkae069
Contributors: Jaime A Espinoza; Dimitris C Kanellis; Sheetanshu Saproo; Karla Leal; Johana Fernandez Martinez; Jiri Bartek; Mikael S Lindström
Source: check_circle
Crossref

Longitudinal molecular profiling elucidates immunometabolism dynamics in breast cancer

Nature Communications
2024-05-07 | Journal article
DOI: 10.1038/s41467-024-47932-y
Contributors: Kang Wang; Ioannis Zerdes; Henrik J. Johansson; Dhifaf Sarhan; Yizhe Sun; Dimitris C. Kanellis; Emmanouil G. Sifakis; Artur Mezheyeuski; Xingrong Liu; Niklas Loman et al.
Source: check_circle
Crossref

The exon-junction complex helicase eIF4A3 holds therapeutic potential in acute myeloid leukemia

Leukemia
2024-03 | Journal article
DOI: 10.1038/s41375-023-02098-2
Contributors: Sophia Miliara; Elisabetta Cozzi; Xiangfu Zhong; Isaac Chan; Karl Ekwall; Sören Lehmann; Andreas Lennartsson; Jiri Bartek; Dimitris C. Kanellis
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Actionable cancer vulnerability due to translational arrest, p53 aggregation and ribosome biogenesis stress evoked by the disulfiram metabolite CuET

Cell Death & Differentiation
2023-07 | Journal article
DOI: 10.1038/s41418-023-01167-4
Part of ISSN: 1350-9047
Part of ISSN: 1476-5403
Contributors: Dimitris C. Kanellis; Asimina Zisi; Zdenek Skrott; Bennie Lemmens; Jaime A. Espinoza; Martin Kosar; Andrea Björkman; Xuexin Li; Stefanos Arampatzis; Jirina Bartkova et al.
Source: Self-asserted source
Dimitrios Kanellis
grade
Preferred source (of 2)‎

Small molecule-mediated disruption of ribosome biogenesis synergizes with FGFR inhibitors to suppress glioma cell growth

Neuro-Oncology
2023-06-02 | Journal article
DOI: 10.1093/neuonc/noac286
Contributors: Asimina Zisi; Dimitris C Kanellis; Simon Moussaud; Ida Karlsson; Helena Carén; Lars Bräutigam; Jiri Bartek; Mikael S Lindström
Source: check_circle
Crossref

MDC1 maintains active elongation complexes of RNA polymerase II

Cell Reports
2023-01 | Journal article
DOI: 10.1016/j.celrep.2022.111979
Part of ISSN: 2211-1247
Contributors: George Pappas; Sebastian Howen Nesgaard Munk; Kenji Watanabe; Quentin Thomas; Zita Gál; Helena Hagner Gram; MyungHee Lee; Daniel Gómez-Cabello; Dimitris Christos Kanellis; Pedro Olivares-Chauvet et al.
Source: Self-asserted source
Dimitrios Kanellis

The exon-junction complex helicase eIF4A3 controls cell fate via coordinated regulation of ribosome biogenesis and translational output

Science Advances
2021-08-06 | Journal article
DOI: 10.1126/sciadv.abf7561
Contributors: Dimitris C. Kanellis; Jaime A. Espinoza; Asimina Zisi; Elpidoforos Sakkas; Jirina Bartkova; Anna-Maria Katsori; Johan Boström; Lars Dyrskjøt; Helle Broholm; Mikael Altun et al.
Source: check_circle
Crossref

A chemical screen for modulators of mRNA translation identifies a distinct mechanism of toxicity for sphingosine kinase inhibitors

PLOS Biology
2021-05-25 | Journal article
DOI: 10.1371/journal.pbio.3001263
Part of ISSN: 1545-7885
Source: Self-asserted source
Dimitrios Kanellis

Human RTEL1 associates with Poldip3 to facilitate responses to replication stress and R-loop resolution

Genes & Development
2020-06-19 | Journal article
DOI: 10.1101/gad.330050.119
Part of ISSN: 0890-9369
Part of ISSN: 1549-5477
Source: Self-asserted source
Dimitrios Kanellis
grade
Preferred source (of 2)‎

The antimalarial drug amodiaquine stabilizes p53 through ribosome biogenesis stress, independently of its autophagy-inhibitory activity

Cell Death & Differentiation
2019-07-08 | Journal article
DOI: 10.1038/s41418-019-0387-5
Part of ISSN: 1350-9047
Part of ISSN: 1476-5403
Source: Self-asserted source
Dimitrios Kanellis
grade
Preferred source (of 3)‎

Apolipoprotein A-I inhibits experimental colitis and colitis-propelled carcinogenesis.

Oncogene
2016-05 | Journal article
DOI: 10.1038/onc.2015.307
PMID: 26279300
Contributors: Gkouskou KK; Ioannou M; Pavlopoulos GA; Georgila K; Siganou A; Nikolaidis G; Kanellis DC; Moore S; Papadakis KA; Kardassis D et al.
Source: Self-asserted source
Dimitrios Kanellis via Europe PubMed Central
grade
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Physical and functional interaction of the TPL2 kinase with nucleophosmin

Oncogene
2015 | Journal article
DOI: 10.1038/onc.2014.183
SOURCE-WORK-ID:

131241729

PMID: 24998852
Contributors: Kanellis, DC; Bursac, S; Tsichlis, PN; Volarevic, S; Eliopoulos, AG
Source: check_circle
Karolinska Institutet
grade
Preferred source (of 2)‎

Tpl2 interacts with and regulates NPM expression levels under genotoxic stress

FEBS J.
2013 | Conference abstract
SOURCE-WORK-ID:

127666751
Contributors: Kanellis, DC; Tsichlis, PN; Eliopoulos, AG
Source: check_circle
Karolinska Institutet

TPL2 kinase is a suppressor of lung carcinogenesis

Proc. Natl. Acad. Sci. U.S.A.
2013 | Journal article
DOI: 10.1073/pnas.1215938110
SOURCE-WORK-ID:

126665366

PMID: 23533274
Contributors: Gkirtzimanaki, K; Gkouskou, KK; Oleksiewicz, U; Nikolaidis, G; Vyrla, D; Liontos, M; Pelekanou, V; Kanellis, DC; Evangelou, K; Stathopoulos, EN et al.
Source: check_circle
Karolinska Institutet
grade
Preferred source (of 2)‎

Tpl2 kinase signal transduction in inflammation and cancer

Cancer Lett.
2011 | Journal article
DOI: 10.1016/j.canlet.2011.02.004
SOURCE-WORK-ID:

122364579

PMID: 21377269
Contributors: Vougioukalaki, M; Kanellis, DC; Gkouskou, K; Eliopoulos, AG
Source: check_circle
Karolinska Institutet
grade
Preferred source (of 2)‎

Peer review (13 reviews for 9 publications/grants)

Review activity for Biochemistry and cell biology. (2)
Review activity for Bioinformatics and biology insights. (1)
Review activity for Cancer gene therapy. (1)
Review activity for Cell death and disease. (1)
Review activity for Cells. (2)
Review activity for DNA and cell biology. (1)
Review activity for International journal of molecular sciences. (3)
Review activity for Molecular biology reports. (1)
Review activity for Molecular biology reports. (1)
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