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Scopus Author ID: 26539007100

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Education and qualifications (1)

Helwan University Faculty of Pharmacy: Cairo, EG

2015-04-01 to present | Prof. (Biochemistry and Molecular Biology)
Education
Source: Self-asserted source
Mahmoud Youns

Works (45)

Cytotoxic Activity of Zinc Oxide Nanoparticles Mediated by Euphorbia Retusa

Crystals
2022-06 | Journal article | Author
DOI: 10.3390/cryst12070903
Contributors: Abdulsalam A. Alqahtani; Hany Gouda; Abdelbaset Elgamal; Mohamed Aleraky; Mahmoud Youns; Ammar M. Ibrahim; Randa Abdou; Ibrahim Ahmed Shaikh; Mohamed El Raey
Source: check_circle
Multidisciplinary Digital Publishing Institute

Synthesis, Antimicrobial, Anti-Virulence and Anticancer Evaluation of New 5(4<i>H</i>)-Oxazolone-Based Sulfonamides

Molecules
2022-01 | Journal article | Author
DOI: 10.3390/molecules27030671
Contributors: Ahmad Almalki; Tarek Ibrahim; Ehab; Mamdouh F. A. Mohamed; Mahmoud Youns; Wael Hegazy; Amany M. M. Al-Mahmoudy
Source: check_circle
Multidisciplinary Digital Publishing Institute

Not Only Antimicrobial: Metronidazole Mitigates the Virulence of <i>Proteus mirabilis</i> Isolated from Macerated Diabetic Foot Ulcer

Applied Sciences
2021-07 | Journal article | Author
DOI: 10.3390/app11156847
Contributors: Ahdab N. Khayyat; Hisham A Abbas; Mamdouh F. A. Mohamed; Hani Z. Asfour; Maan T. Khayat; Tarek Ibrahim; Mahmoud Youns; El-Sayed Khafagy; Amr Abu Lila; Martin Safo et al.
Source: check_circle
Multidisciplinary Digital Publishing Institute

Design, Synthesis, Molecular Modeling and Antitumor Evaluation of Novel Indolyl-Pyrimidine Derivatives with EGFR Inhibitory Activity

Molecules
2021-03 | Journal article | Author
DOI: 10.3390/molecules26071838
Contributors: Naglaa M. Ahmed; Mahmoud Youns; Moustafa K.Soltan; Ahmed M. Said
Source: check_circle
Multidisciplinary Digital Publishing Institute

Investigating the influence of iron on Campylobacter jejuni transcriptome in response to acid stress

Microbial Pathogenesis
2020 | Journal article
DOI: 10.1016/j.micpath.2019.103777
EID:

2-s2.0-85073190941

Part of ISBN:

10961208 08824010
Contributors: Askoura, M.; Youns, M.; Halim Hegazy, W.A.
Source: Self-asserted source
Mahmoud Youns via Scopus - Elsevier
grade
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Design, synthesis, molecular modelling, and biological evaluation of novel substituted pyrimidine derivatives as potential anticancer agents for hepatocellular carcinoma

Journal of Enzyme Inhibition and Medicinal Chemistry
2019 | Journal article
DOI: 10.1080/14756366.2019.1612889
EID:

2-s2.0-85066395769

Part of ISBN:

14756374 14756366
Contributors: Ahmed, N.M.; Youns, M.; Soltan, M.K.; Said, A.M.
Source: Self-asserted source
Mahmoud Youns via Scopus - Elsevier
grade
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Rutin and orlistat produce antitumor effects via antioxidant and apoptotic actions

Naunyn-Schmiedeberg's Archives of Pharmacology
2019 | Journal article
DOI: 10.1007/s00210-018-1579-0
EID:

2-s2.0-85057106524

Part of ISBN:

14321912 00281298
Contributors: Saleh, A.; ElFayoumi, H.M.; Youns, M.; Barakat, W.
Source: Self-asserted source
Mahmoud Youns via Scopus - Elsevier
grade
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Differentially tolerized mouse antigen presenting cells share a common miRNA signature including enhanced mmu-miR-223-3p expression which is sufficient to imprint a protolerogenic state

Frontiers in Pharmacology
2018 | Journal article
DOI: 10.3389/fphar.2018.00915
EID:

2-s2.0-85051626040

Part of ISBN:

16639812
Contributors: Bros, M.; Youns, M.; Kollek, V.; Buchmüller, D.; Bollmann, F.; Seo, E.-J.; Schupp, J.; Montermann, E.; Usanova, S.; Kleinert, H. et al.
Source: Self-asserted source
Mahmoud Youns via Scopus - Elsevier
grade
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Novel hydrazide-hydrazone and amide substituted coumarin derivatives: Synthesis, cytotoxicity screening, microarray, radiolabeling and in vivo pharmacokinetic studies

European Journal of Medicinal Chemistry
2018 | Journal article
DOI: 10.1016/j.ejmech.2018.04.014
EID:

2-s2.0-85045730870

Part of ISBN:

17683254 02235234
Contributors: Nasr, T.; Bondock, S.; Rashed, H.M.; Fayad, W.; Youns, M.; Sakr, T.M.
Source: Self-asserted source
Mahmoud Youns via Scopus - Elsevier
grade
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The growth inhibitory effect of gambogic acid on pancreatic cancer cells

Naunyn-Schmiedeberg's Archives of Pharmacology
2018 | Journal article
DOI: 10.1007/s00210-018-1485-5
EID:

2-s2.0-85044028399

Part of ISBN:

14321912 00281298
Contributors: Youns, M.а.; ElKhoely, A.; Kamel, R.
Source: Self-asserted source
Mahmoud Youns via Scopus - Elsevier
grade
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Anticancer activity of salicin and fenofibrate

Naunyn-Schmiedeberg's Archives of Pharmacology
2017 | Journal article
DOI: 10.1007/s00210-017-1407-y
EID:

2-s2.0-85025473252

Part of ISBN:

14321912 00281298
Contributors: Sabaa, M.; Elfayoumi, H.M.; Elshazly, S.; Youns, M.; Barakat, W.
Source: Self-asserted source
Mahmoud Youns via Scopus - Elsevier
grade
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Synthesis and evaluation of cytotoxic activity of some pyrroles and fused pyrroles

Anti-Cancer Agents in Medicinal Chemistry
2017 | Journal article
DOI: 10.2174/1871520617666170102152928
EID:

2-s2.0-85025116961

Part of ISBN:

18755992 18715206
Contributors: Fatahala, S.S.; Mohamed, M.S.; Youns, M.; Hameed, R.H.A.-E.
Source: Self-asserted source
Mahmoud Youns via Scopus - Elsevier
grade
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Synthesis, antitumor evaluation and microarray study of some new pyrazolo[3,4-d][1,2,3]triazine derivatives

European Journal of Medicinal Chemistry
2017 | Journal article
DOI: 10.1016/j.ejmech.2017.10.016
EID:

2-s2.0-85032293506

Part of ISBN:

17683254 02235234
Contributors: Nasr, T.; Bondock, S.; Youns, M.; Fayad, W.; Zaghary, W.
Source: Self-asserted source
Mahmoud Youns via Scopus - Elsevier
grade
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The natural flavonoid fisetin inhibits cellular proliferation of hepatic, colorectal, and pancreatic cancer cells through modulation of multiple signaling pathways

PLoS ONE
2017 | Journal article
DOI: 10.1371/journal.pone.0169335
EID:

2-s2.0-85008392019

Part of ISBN:

19326203
Contributors: Youns, M.; Hegazy, W.A.H.
Source: Self-asserted source
Mahmoud Youns via Scopus - Elsevier
grade
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A new sucrase enzyme inhibitor from Azadirachta indica

Pharmacognosy Magazine
2016 | Journal article
DOI: 10.4103/0973-1296.185705
EID:

2-s2.0-85047500226

Part of ISBN:

09764062 09731296
Contributors: Abdelhady, M.I.S.; Shaheen, U.; Bader, A.; Youns, M.A.
Source: Self-asserted source
Mahmoud Youns via Scopus - Elsevier
grade
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Design, synthesis, molecular docking and anti-breast cancer activity of novel quinazolinones targeting estrogen receptor α

Acta Poloniae Pharmaceutica - Drug Research
2016 | Journal article
EID:

2-s2.0-84943449578

Part of ISBN:

00016837
Contributors: Ahmed, M.F.; Youns, M.; Belal, A.
Source: Self-asserted source
Mahmoud Youns via Scopus - Elsevier
grade
Preferred source (of 2)‎

Synthesis and anticancer evaluation of novel isoxazole/pyrazole derivatives

Research on Chemical Intermediates
2016 | Journal article
DOI: 10.1007/s11164-015-2091-5
EID:

2-s2.0-84929698597

Part of ISBN:

15685675 09226168
Contributors: Abu Bakr, S.M.; Abd El-Karim, S.S.; Said, M.M.; Youns, M.M.
Source: Self-asserted source
Mahmoud Youns via Scopus - Elsevier
grade
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TALENs construction: Slowly but surely

Asian Pacific Journal of Cancer Prevention
2016 | Journal article
EID:

2-s2.0-84983372583

Part of ISBN:

15137368
Contributors: Hegazy, W.A.H.; Youns, M.
Source: Self-asserted source
Mahmoud Youns via Scopus - Elsevier
grade
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Design, synthesis, molecular modeling and anti-breast cancer activity of novel quinazolin-4-one derivatives linked to thiazolidinone, oxadiazole or pyrazole moieties

Medicinal Chemistry Research
2015 | Journal article
DOI: 10.1007/s00044-015-1357-1
EID:

2-s2.0-84943454524

Part of ISBN:

15548120 10542523
Contributors: Ahmed, M.F.; Belal, A.; Youns, M.
Source: Self-asserted source
Mahmoud Youns via Scopus - Elsevier
grade
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Anti-infective and cytotoxic properties of Bupleurum marginatum

Chinese Medicine (United Kingdom)
2014 | Journal article
DOI: 10.1186/1749-8546-9-4
EID:

2-s2.0-84892982169

Part of ISBN:

17498546
Contributors: Ashour, M.L.; El-Readi, M.Z.; Hamoud, R.; Eid, S.Y.; El Ahmady, S.H.; Nibret, E.; Herrmann, F.; Youns, M.; Tahrani, A.; Kaufmann, D. et al.
Source: Self-asserted source
Mahmoud Youns via Scopus - Elsevier
grade
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Anticancer activity of new coumarin substituted hydrazide-hydrazone derivatives

European Journal of Medicinal Chemistry
2014 | Journal article
DOI: 10.1016/j.ejmech.2014.02.026
EID:

2-s2.0-84897544142

Part of ISBN:

17683254 02235234
Contributors: Nasr, T.; Bondock, S.; Youns, M.
Source: Self-asserted source
Mahmoud Youns via Scopus - Elsevier
grade
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Novel indolyl-pyrimidine derivatives: Synthesis, antimicrobial, and antioxidant evaluations

Medicinal Chemistry Research
2014 | Journal article
DOI: 10.1007/s00044-014-0916-1
EID:

2-s2.0-84902380724

Part of ISBN:

15548120 10542523
Contributors: Mohamed, M.S.; Youns, M.M.; Ahmed, N.M.
Source: Self-asserted source
Mahmoud Youns via Scopus - Elsevier
grade
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Novel series of substituted heterocycles derived from α,β-unsaturated ketones for anticancer evaluation

Research Journal of Pharmaceutical, Biological and Chemical Sciences
2014 | Journal article
EID:

2-s2.0-84896520965

Part of ISBN:

09758585
Contributors: Gouhar, R.S.; Youns, M.
Source: Self-asserted source
Mahmoud Youns via Scopus - Elsevier
grade
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Novel synthesis and anti-tumour activity of 2-hydrazino-1h-benzimidazoles

Research Journal of Pharmaceutical, Biological and Chemical Sciences
2013 | Journal article
EID:

2-s2.0-84891136869

Part of ISBN:

09758585
Contributors: Abu-Bakr, S.H.M.; Abu-Zied, K.H.M.; Youns, M.; Hashim, A.; El-Diwan, H.I.
Source: Self-asserted source
Mahmoud Youns via Scopus - Elsevier
grade
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Serum talin-1 is a potential novel biomarker for diagnosis of hepatocellular carcinoma in Egyptian patients

Asian Pacific Journal of Cancer Prevention
2013 | Journal article
DOI: 10.7314/APJCP.2013.14.6.3819
EID:

2-s2.0-84882671504

Part of ISBN:

2476762X 15137368
Contributors: Youns, M.M.; Abdel Wahab, A.H.A.; Hassan, Z.A.; Attia, M.S.
Source: Self-asserted source
Mahmoud Youns via Scopus - Elsevier
grade
Preferred source (of 2)‎

Synthesis and biological evaluation of a novel series of 6,8-dibromo-4(3H)quinazolinone derivatives as anticancer agents

Archiv der Pharmazie
2013 | Journal article
DOI: 10.1002/ardp.201300158
EID:

2-s2.0-84881376899

Part of ISBN:

03656233 15214184
Contributors: Ahmed, M.F.; Youns, M.
Source: Self-asserted source
Mahmoud Youns via Scopus - Elsevier
grade
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Synthesis, antimicrobial, antioxidant activities of novel 6-aryl-5-cyano thiouracil derivatives

European Journal of Medicinal Chemistry
2013 | Journal article
DOI: 10.1016/j.ejmech.2013.08.032
EID:

2-s2.0-84884698050

Part of ISBN:

02235234 17683254
Contributors: Mohamed, M.S.; Youns, M.M.; Ahmed, N.M.
Source: Self-asserted source
Mahmoud Youns via Scopus - Elsevier
grade
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Synthesis, structural elucidation, and in vitro antitumor activities of some pyrazolopyrimidines and schiff bases derived from 5-amino-3-(arylamino)-1H-pyrazole-4-carboxamides

Scientia Pharmaceutica
2013 | Journal article
DOI: 10.3797/scipharm.1211-07
EID:

2-s2.0-84879288573

Part of ISBN:

00368709 22180532
Contributors: Hafez, T.S.; Osman, S.A.; Yosef, H.A.A.; Abd El-All, A.S.; Hassan, A.S.; El-Sawy, A.A.; Abdallah, M.M.; Youns, M.
Source: Self-asserted source
Mahmoud Youns via Scopus - Elsevier
grade
Preferred source (of 2)‎

Upregulation of extrinsic apoptotic pathway in curcumin-mediated antiproliferative effect on human pancreatic carcinogenesis

Journal of Cellular Biochemistry
2013 | Journal article
DOI: 10.1002/jcb.24612
EID:

2-s2.0-84885625894

Part of ISBN:

07302312 10974644
Contributors: Youns, M.; Fathy, G.M.
Source: Self-asserted source
Mahmoud Youns via Scopus - Elsevier
grade
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Chemistry of phosphorus ylides 32: Synthesis of phosphoranylidene-pyrano- and -cyclobutyl-xanthenones with potential antitumor activity

Monatshefte fur Chemie
2012 | Journal article
DOI: 10.1007/s00706-011-0683-3
EID:

2-s2.0-84861342832

Part of ISBN:

00269247
Contributors: Soliman, F.M.; Said, M.M.; Youns, M.; Darwish, S.A.
Source: Self-asserted source
Mahmoud Youns via Scopus - Elsevier
grade
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Immunoassay-based proteome profiling of 24 pancreatic cancer cell lines

Journal of Proteomics
2012 | Journal article
DOI: 10.1016/j.jprot.2012.04.042
EID:

2-s2.0-84862233043

Part of ISBN:

18743919 18767737
Contributors: Alhamdani, M.S.S.; Youns, M.; Buchholz, M.; Gress, T.M.; Beckers, M.-C.; Maréchal, D.; Bauer, A.; Schröder, C.; Hoheisel, J.D.
Source: Self-asserted source
Mahmoud Youns via Scopus - Elsevier
grade
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Serum levels of heat shock protein 27 as a potential marker of diabetic nephropathy in Egyptians with type 2 diabetes

Journal of Applied Pharmaceutical Science
2012 | Journal article
DOI: 10.7324/japs.2012.21104
EID:

2-s2.0-84876031161

Part of ISBN:

22313354
Contributors: Mahgoub, S.; Youns, M.; Bassyouni, A.; Hassan, Z.
Source: Self-asserted source
Mahmoud Youns via Scopus - Elsevier
grade
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Anti-inflammatory and anti-cancer activities of essential oils and their biological constituents

International Journal of Clinical Pharmacology and Therapeutics
2011 | Journal article
DOI: 10.5414/CPP49093
EID:

2-s2.0-78650826132

Part of ISBN:

09461965
Contributors: Torres Salazar, A.; Hoheisel, J.; Youns, M.; Wink, M.
Source: Self-asserted source
Mahmoud Youns via Scopus - Elsevier
grade
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Biological activities of xanthatin from Xanthium strumarium leaves

Phytotherapy Research
2011 | Journal article
DOI: 10.1002/ptr.3651
EID:

2-s2.0-82155172880

Part of ISBN:

0951418X 10991573
Contributors: Nibret, E.; Youns, M.; Krauth-Siegel, R.L.; Wink, M.
Source: Self-asserted source
Mahmoud Youns via Scopus - Elsevier
grade
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Cytotoxicity of some Cameroonian spices and selected medicinal plant extracts

Journal of Ethnopharmacology
2011 | Journal article
DOI: 10.1016/j.jep.2011.01.035
EID:

2-s2.0-79954415842

Part of ISBN:

03788741
Contributors: Kuete, V.; Krusche, B.; Youns, M.; Voukeng, I.; Fankam, A.G.; Tankeo, S.; Lacmata, S.; Efferth, T.
Source: Self-asserted source
Mahmoud Youns via Scopus - Elsevier
grade
Preferred source (of 2)‎

Therapeutic and diagnostic applications of nanoparticles

Current Drug Targets
2011 | Journal article
DOI: 10.2174/138945011794815257
EID:

2-s2.0-79551623194

Part of ISBN:

13894501
Contributors: Youns, M.; Hoheisel, J.D.; Efferth, T.
Source: Self-asserted source
Mahmoud Youns via Scopus - Elsevier
grade
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Transcript profiling identifies novel key players mediating the growth inhibitory effect of NS-398 on human pancreatic cancer cells

European Journal of Pharmacology
2011 | Journal article
DOI: 10.1016/j.ejphar.2010.10.026
EID:

2-s2.0-78649727958

Part of ISBN:

00142999
Contributors: Youns, M.; Efferth, T.; Hoheisel, J.D.
Source: Self-asserted source
Mahmoud Youns via Scopus - Elsevier
grade
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Berberine inhibits cell growth and mediates caspase-independent cell death in human pancreatic cancer cells

Planta Medica
2010 | Journal article
DOI: 10.1055/s-0030-1249931
EID:

2-s2.0-77955043937

Part of ISBN:

00320943 14390221
Contributors: Pinto-Garcia, L.; Efferth, T.; Torres, A.; Hoheisel, J.D.; Youns, M.
Source: Self-asserted source
Mahmoud Youns via Scopus - Elsevier
grade
Preferred source (of 2)‎

Biological activity of the essential oil of Kadsura longipedunculata (Schisandraceae) and its major components

Journal of Pharmacy and Pharmacology
2010 | Journal article
DOI: 10.1111/j.2042-7158.2010.01119.x
EID:

2-s2.0-77954950720

Part of ISBN:

00223573
Contributors: Mulyaningsih, S.; Youns, M.; El-Readi, M.Z.; Ashour, M.L.; Nibret, E.; Sporer, F.; Herrmann, F.; Reichling, J.; Wink, M.
Source: Self-asserted source
Mahmoud Youns via Scopus - Elsevier
grade
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Epigenetically deregulated microRNA-375 is involved in a positive feedback loop with estrogen receptor α in breast cancer cells

Cancer Research
2010 | Journal article
DOI: 10.1158/0008-5472.CAN-10-1318
EID:

2-s2.0-78549249846

Part of ISBN:

00085472 15387445
Contributors: Rocha Simonini, P.D.S.; Breiling, A.; Gupta, N.; Malekpour, M.; Youns, M.; Omranipour, R.; Malekpour, F.; Volinia, S.; Croce, C.M.; Najmabadi, H. et al.
Source: Self-asserted source
Mahmoud Youns via Scopus - Elsevier
grade
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Sensitivity and resistance towards isoliquiritigenin, doxorubicin and methotrexate in T cell acute lymphoblastic leukaemia cell lines by pharmacogenomics

Naunyn-Schmiedeberg's Archives of Pharmacology
2010 | Journal article
DOI: 10.1007/s00210-010-0541-6
EID:

2-s2.0-77957584403

Part of ISBN:

00281298
Contributors: Youns, M.; Fu, Y.-J.; Zu, Y.-G.; Kramer, A.; Konkimalla, V.B.; Radlwimmer, B.; Sültmann, H.; Efferth, T.
Source: Self-asserted source
Mahmoud Youns via Scopus - Elsevier
grade
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Toxicogenomics for the prediction of toxicity related to herbs from traditional Chinese medicine

Planta Medica
2010 | Journal article
DOI: 10.1055/s-0030-1250432
EID:

2-s2.0-78649904210

Part of ISBN:

00320943 14390221
Contributors: Youns, M.; Hoheisel, J.D.; Efferth, T.
Source: Self-asserted source
Mahmoud Youns via Scopus - Elsevier
grade
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Traditional Chinese Medicines (TCMs) for molecular targeted therapies of tumours

Current Drug Discovery Technologies
2010 | Journal article
DOI: 10.2174/157016310791162730
EID:

2-s2.0-77951748113

Part of ISBN:

15701638
Contributors: Youns, M.; Hoheisel, J.D.; Efferth, T.
Source: Self-asserted source
Mahmoud Youns via Scopus - Elsevier
grade
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Chemical composition and biological activity of the essential oil obtained from Bupleurum marginatum (Apiaceae)

Journal of Pharmacy and Pharmacology
2009 | Journal article
DOI: 10.1211/jpp/61.08.0012
EID:

2-s2.0-70249092925

Part of ISBN:

00223573
Contributors: Ashour, M.L.; El-Readi, M.; Youns, M.; Mulyaningsiha, S.; Sporer, F.; Efferth, T.; Wink, M.
Source: Self-asserted source
Mahmoud Youns via Scopus - Elsevier
grade
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Gene expression profiling identifies novel key players involved in the cytotoxic effect of Artesunate on pancreatic cancer cells

Biochemical Pharmacology
2009 | Journal article
DOI: 10.1016/j.bcp.2009.04.014
EID:

2-s2.0-65749103049

Part of ISBN:

00062952
Contributors: Youns, M.; Efferth, T.; Reichling, J.; Fellenberg, K.; Bauer, A.; Hoheisel, J.D.
Source: Self-asserted source
Mahmoud Youns via Scopus - Elsevier
grade
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Peer review (5 reviews for 4 publications/grants)

Review activity for ["Journal of Genetic Engineering and Biotechnology.","مجلة المركز القومي للبحوث للتكنولوجيا الحيوية"] (1)
Review activity for BMC complementary medicine and therapies. (1)
Review activity for Naunyn-Schmiedeberg's archives of pharmacology (1)
Review activity for PloS one. (2)
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