Personal information

Verified email addresses

Verified email domains

Biotechnology, Polymeric delivery systems, Immunology, Metabolism, Wound healing
Portugal

Biography

Jessica Da Silva is actually attending the Ph.D. Programme in Experimental Biology and Biomedicine (PDBEB) 2020/2021 from the Institute for Interdisciplinary Research of the University of Coimbra with a FCT individual PhD scholarship. She also integrated the Fulbright community having be awarded a Fulbright scholarship for research with the support of FCT to develop part of her Ph.D. at UC Davis, CA, U.S. She completed her Master Degree in Pharmaceutical Biotechnology in 2019 (Faculty of Pharmacy, University of Coimbra), with a dissertation entitled "Evaluation of the immunotoxicological properties of PLA nanoparticles", and her Bachelor Degree in Biomedical Sciences in 2017 (Department of Medical Sciences, University of Aveiro). Moreover, she is currently a researcher at CNC-UC (CIBB, University of Coimbra), being a laboratory member of the Metabolism, Aging and Disease - Obesity, Diabetes and Complications Group. Furthermore, she has been accredited as investigator for scientific experimentation involving animals (rats and mice) attributed by DGAV (Direção Geral de Alimentação e Veterinária, Portugal) - Course on Laboratory Animal Sciences - FELASA Category B certification.

Activities

Employment (3)

CNC.IBILI: Coimbra, Coimbra, PT

2019-12-01 to present | Researcher (Metabolism, Aging and Disease – Obesity, Diabetes and Complications)
Employment
Source: Self-asserted source
Da Silva, Jessica

University of California, Davis: Davis, California, US

2022-01 to 2022-08 | Visiting Researcher (Department of Biomedical Engineering)
Employment
Source: Self-asserted source
Da Silva, Jessica

CNC.IBILI: Coimbra, Coimbra, PT

2018-12 to 2019-07 | Research Trainee ( Nanotechnology-based vaccine adjuvants)
Employment
Source: Self-asserted source
Da Silva, Jessica

Education and qualifications (5)

University of Coimbra: Coimbra, PT

2020-09 to present | PhD in Experimental Biology and Biomedicine (Institute for Interdisciplinary Research)
Education
Source: Self-asserted source
Da Silva, Jessica

University of Coimbra: Coimbra, PT

2017-09 to 2019-07 | Master in Pharmaceutical Biotechnology (Faculty of Pharmacy)
Education
Source: Self-asserted source
Da Silva, Jessica

Sociedade Portuguesa de Ciências em Animais de Laboratório: Coimbra, PT

2019-06-26 to 2019-06-29 | Practical Course of Laboratory Animal Sciences (22h)
Education
Source: Self-asserted source
Da Silva, Jessica

Sociedade Portuguesa de Ciências em Animais de Laboratório: Coimbra, PT

2018-09-13 to 2019-06 | On-line Theoretical Course of Laboratory Animal Sciences (20h)
Education
Source: Self-asserted source
Da Silva, Jessica

University of Aveiro: Aveiro, PT

2014-09 to 2017-07 | Bachelor in Biomedical Sciences (Department of Medical Sciences)
Education
Source: Self-asserted source
Da Silva, Jessica

Professional activities (1)

Direcção-Geral de Alimentação e Veterinária: Lisboa, PT

2019-12-09 | Accreditation as Investigator for scientific experimentation involving animals (rats and mice)
Distinction
Source: Self-asserted source
Da Silva, Jessica

Funding (3)

Alginate-based hydrogels with controlled release of antimicrobial peptides to control diabetic foot infection

2020-10-01 to 2024-09-30 | Grant
Fundação para a Ciência e a Tecnologia (Lisboa, PT)
GRANT_NUMBER:

2020.04990.BD

Source: check_circle
CIÊNCIAVITAE

HealthyAging 2020

2019-12 to 2020-08 | Contract
European Regional Development Fund (Brussels, BE)
GRANT_NUMBER:

HEALTHYAGING 2020 (CENTRO-01- 0145-FEDER-000012)

Source: check_circle
CIÊNCIAVITAE

Polymeric NanoBioMaterials for drug delivery: developing and implementation of safe-by-design concept enabling safe healthcare solutions

2018-12 to 2019-07 | Contract
Fundação para a Ciência e a Tecnologia (Lisboa, PT)
GRANT_NUMBER:

ProSafe JTC/0001/2016

Source: check_circle
CIÊNCIAVITAE

Works (30)

Enhancement of wound healing in diabetic mice by topical use of a peptide-ionic liquid conjugate

International Journal of Biochemistry and Cell Biology
2025-02-14 | Journal article
SOURCE-WORK-ID:

cv-prod-id-4561142

Part of ISSN: 1357-2725
Contributors: Gomes, Ana; Leal, Ermelindo C.; Da Silva, J.; Teixeira, Inês; Ferraz, Ricardo; Calheiros, Daniela; Gonçalves, Teresa; Carvalho, Eugénia; Gomes, Paula
Source: check_circle
CIÊNCIAVITAE

Pathogen defense and tissue protection mechanisms are dysregulated in the early stages of wound healing in diabetes

ETRS-WHS-SKINTERM 2024
2024-09-25 | Conference poster
SOURCE-WORK-ID:

cv-prod-id-4489654

Contributors: Leal, Ermelindo C; Santa, C.; Santos, M.; Da Silva, Jessica; Zachariou, M.; Spyrou, G. M.; Manadas, Bruno; Carvalho, Eugenia
Source: check_circle
CIÊNCIAVITAE

Peptide-based ionic liquids for non-healing wounds: in vivo data from a mouse model of diabetic ulcers

37th EPS – European Peptide Symposium 2024
2024-08-25 | Conference poster
SOURCE-WORK-ID:

cv-prod-id-4489618

Contributors: Gomes, Ana; Ferraz, Ricardo; Ferreira, M.; Da Silva, Jessica; Teixeira, Inês; Calheiros, Daniela; Teixeira, C.; et al.
Source: check_circle
CIÊNCIAVITAE

Association between COVID-19 and the incidence of type 1 diabetes in Portugal – a registry study

BMC Endocrine Disorders
2024-08-09 | Journal article
SOURCE-WORK-ID:

cv-prod-id-4489534

Part of ISSN: 1472-6823
Contributors: Bjerregaard-Andersen, Morten; Da Silva, J.; Diogo, Rui; Claro, Ana Raquel; Ferro, Inês; Romana, Andreia; Rocha, Patrícia; et al.
Source: check_circle
CIÊNCIAVITAE

New Insights in Diabetic Foot Ulcer Mechanisms: DNA Methylation and Non-coding RNAs

Revista Portuguesa de Diabetes
2024-06 | Journal article
SOURCE-WORK-ID:

cv-prod-id-4489613

Contributors: Da Silva, Jessica; Santos, Diana; Carvalho, Eugenia; Leal, Ermelindo C
Source: check_circle
CIÊNCIAVITAE

Impact of Psychological Distress on Physiological Indicators of Healing Prognosis in Patients with Chronic Diabetic Foot Ulcers: A Longitudinal Study

Advances in Wound Care
2024-06-01 | Journal article
Contributors: Jessica Da Silva; Diana Santos; Margarida Vilaça; André Carvalho; Rui Carvalho; Maria de Jesus Dantas; M. Graça Pereira; Eugénia Carvalho
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Materiais de origem celular como potenciadores de imunossupressão localizada

20º Congresso Português de Diabetes - 2024
2024-03-07 | Conference poster
SOURCE-WORK-ID:

cv-prod-id-4222603

Contributors: Cunha, Ana Filipa; Sousa, Ana Rita; Da Silva, Jessica; Carvalho, Eugenia; Mano, Joao F.; Leal, Ermelindo C; Oliveira, Mariana B.
Source: check_circle
CIÊNCIAVITAE

Healing profiles in patients with a chronic diabetic foot ulcer: An exploratory study with machine learning

Wound Repair and Regeneration
2023-11 | Journal article
SOURCE-WORK-ID:

cv-prod-id-3758430

Contributors: Pereira, M. Graça; Vilaça, Margarida; Braga, Diogo; Madureira, Ana; Da Silva, Jéssica; Santos, Diana; Carvalho, Eugénia
Source: check_circle
CIÊNCIAVITAE

Peptide-ionic liquid conjugates: paving the way towards a new type of topical treatment for infected wounds

ETRS & SPCE-TC Joint Meeting 2023
2023-10-13 | Conference poster
SOURCE-WORK-ID:

cv-prod-id-3530150

Contributors: Gomes, Ana; Maciel, J.; Ferreira, M.; Plácido, A.; Fernandes, I.; Teixeira, C.; Leal, Ermelindo C; et al.
Source: check_circle
CIÊNCIAVITAE

Psychological distress' impact on immune cell distribution and plasma microRNAs in patients with chronic diabetic foot ulcers - a longitudinal study

ETRS & SPCE-TC Joint Meeting 2023
2023-10-12 | Conference poster
SOURCE-WORK-ID:

cv-prod-id-3530160

Contributors: Da Silva, Jessica; Santos, Diana; Vilaça, Margarida; Jesus, Maria; Carvalho, André; Carvalho, Rui; Pereira, Maria de Graça; Carvalho, Eugenia
Source: check_circle
CIÊNCIAVITAE

GreenLabsCIBB - One path for sustainable research

GreenLabs Portugal Symposium: Promoting sustainability in Research
2023-09-22 | Conference poster
SOURCE-WORK-ID:

cv-prod-id-3530111

Contributors: Santos, Bárbara; Afonso, Mariana; Alves, André; Amaral, Sandra; Candeias, Emanuel; Cardoso, Maria; Cortes, Luisa; et al.
Source: check_circle
CIÊNCIAVITAE

GreenLabs @CIBB - "Collection Points" - Reuse and Recycling

GreenLabs Portugal Symposium: Promoting sustainability in Research
2023-09-21 | Conference poster
SOURCE-WORK-ID:

cv-prod-id-3530129

Contributors: Mendes, Candida; Marques, Carla; Mota, Sandra; Afonso, Mariana; Alves, André; Amaral, Sandra; Candeias, Emanuel; et al.
Source: check_circle
CIÊNCIAVITAE

Innovative Functional Biomaterials as Therapeutic Wound Dressings for Chronic Diabetic Foot Ulcers

International Journal of Molecular Sciences
2023-06-08 | Journal article
Contributors: Jessica Da Silva; Ermelindo C. Leal; Eugénia Carvalho; Eduardo A. Silva
Source: check_circle
Crossref
grade
Preferred source (of 3)‎

Associação entre COVID-19 e incidência de diabetes tipo I em Portugal - um estudo de registo

19º Congresso Português de Diabetes - 2023
2023-03-16 | Conference poster
SOURCE-WORK-ID:

cv-prod-id-3328875

Part of ISSN: 1646-3994
Contributors: Bjerregaard-Andersen, Morten; Da Silva, Jessica; Sampaio, M. L.; Claro, A.; Ferro, I.; Romana, A.; Rocha, P.; et al.
Source: check_circle
CIÊNCIAVITAE

Efeito de um conjugado péptido-líquido iónico inovador no tratamento da ferida diabética

19º Congresso Português de Diabetes - 2023
2023-03-16 | Conference poster
SOURCE-WORK-ID:

cv-prod-id-3328871

Part of ISSN: 1646-3994
Contributors: Teixeira, Inês; Da Silva, Jessica; Gomes, Ana; Calheiros, Daniela; Gonçalves, Teresa; Carvalho, Eugenia; Leal, Ermelindo C; Gomes, Paula
Source: check_circle
CIÊNCIAVITAE

Hidrogéis funcionais como sistemas de entrega de péptidos antimicrobianos para o tratamento da úlcera do pé diabético

19º Congresso Português de Diabetes - 2023
2023-03-16 | Conference poster
SOURCE-WORK-ID:

cv-prod-id-3328880

Part of ISSN: 1646-3994
Contributors: Da Silva, Jessica; Leal, Ermelindo C; Gomes, Ana; Gomes, Paula; Carvalho, Eugenia; Silva, E. A.
Source: check_circle
CIÊNCIAVITAE

Impacto do distress psicológico na distribuição de populações de células imunes e nos níveis de microRNAs em doentes com úlceras crónicas do pé diabético: um estudo longitudinal

19º Congresso Português de Diabetes - 2023
2023-03-16 | Conference poster
SOURCE-WORK-ID:

cv-prod-id-3328849

Part of ISSN: 1646-3994
Contributors: Carvalho, Eugenia; Santos, Diana; Vilaça, Margarida; Carvalho, André; Carvalho, Rui; Dantas, Maria Jesus; Pereira, Maria de Graça; Da Silva, Jessica
Source: check_circle
CIÊNCIAVITAE

Effect of distress on circulating microRNA levels and immune cell subpopulation distribution in diabetic foot ulcers

IDF World Diabetes Congress 2022
2022-12 | Conference poster
SOURCE-WORK-ID:

cv-prod-id-3261634

Contributors: Da Silva, J.; Santos, Diana; Moura, João; Vilaça, Margarida; Jesus, Maria; Carvalho, André; Carvalho, Rui; Pereira, M.D.G.; Carvalho, Eugenia
Source: check_circle
CIÊNCIAVITAE

Bone morphogenetic protein 7 decreases inflammation and matrix metalloproteinase 9 in improving diabetic wound healing

ETRS Annual Meeting 2022
2022-09 | Conference poster
SOURCE-WORK-ID:

cv-prod-id-3191343

Contributors: Leal, Ermelindo C; Da Silva, Jéssica; Figueiredo, Ana; Tseng, Y.-H.; Carvalho, Eugenia
Source: check_circle
CIÊNCIAVITAE

Bone morphogenetic protein-7 promotes diabetic wound healing by decreasing inflammation and matrix metalloproteinase-9 expression

58th EASD Annual Meeting 2022
2022-09-20 | Conference poster
SOURCE-WORK-ID:

cv-prod-id-3261624

Contributors: Leal, Ermelindo C; Da Silva, Jessica; Figueiredo, Ana; Tseng, Y.-H.; Carvalho, Eugenia
Source: check_circle
CIÊNCIAVITAE

O impacto do distress na expressão de microRNAs circulantes e nos níveis de hemoglobina glicada na úlcera do pé diabético

18º Congresso Português de Diabetes - 2022
2022-03-11 | Conference poster
SOURCE-WORK-ID:

cv-prod-id-3084467

Contributors: Da Silva, Jessica; Santos, Diana; Moura, João; Vilaça, Margarida; Pereira, Maria de Graça; Carvalho, Eugenia
Source: check_circle
CIÊNCIAVITAE

Bone morphogenetic protein-7 promotes diabetic wound healing by decreasing inflammation and matrix metalloproteinase-9 expression

18º Congresso Português de Diabetes - 2022
2022-03-10 | Conference poster
SOURCE-WORK-ID:

cv-prod-id-3084405

Contributors: Leal, Ermelindo C; Da Silva, Jessica; Figueiredo, Ana; Tseng, Y.-H.; Carvalho, Eugenia
Source: check_circle
CIÊNCIAVITAE

Bioactive Antimicrobial Peptides as Therapeutic Agents for Infected Diabetic Foot Ulcers

Biomolecules
2021-12-17 | Journal article
Contributors: Jessica Da Silva; Ermelindo C. Leal; Eugénia Carvalho
Source: check_circle
Crossref
grade
Preferred source (of 3)‎

Unravelling the Immunotoxicity of Polycaprolactone Nanoparticles—Effects of Polymer Molecular Weight, Hydrolysis, and Blends

Chemical Research in Toxicology
2020-11-16 | Journal article
Contributors: Sandra Jesus; Natalia Bernardi; Jessica da Silva; Mariana Colaço; João Panão Costa; Pedro Fonte; Olga Borges
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Polyester Nanoparticle Immunotoxicological Profile

2019 Controlled Release Society Annual Meeting & Exposition
2019-07 | Conference poster
SOURCE-WORK-ID:

cv-prod-id-1222794

Contributors: Jesus, S.; Da Silva, J.; Bernardi, N.; Panão Costa, J.; Borges, O.
Source: check_circle
CIÊNCIAVITAE

Evaluation of the immunotoxicological properties of PLA nanoparticles

Universidade de Coimbra Faculdade de Farmácia
2019-07-25 | Dissertation or Thesis
SOURCE-WORK-ID:

cv-prod-id-1709354

Contributors: Da Silva, J.
Source: check_circle
CIÊNCIAVITAE

Polyester Nanoparticles: relationship between structure and activity

2019 Controlled Release Society Annual Meeting & Exposition
2019-07-24 | Conference poster
SOURCE-WORK-ID:

cv-prod-id-3758432

Contributors: Jesus, Sandra; Da Silva, Jéssica; Bernardi, Nata; Panão Costa, João; Borges, Olga
Source: check_circle
CIÊNCIAVITAE

Poly(D,L-Lactic Acid) Nanoparticle Size Reduction Increases Its Immunotoxicity

Frontiers in Bioengineering and Biotechnology
2019-06-06 | Journal article
SOURCE-WORK-ID:

cv-prod-id-543277

Contributors: Da Silva, J.; Jesus, S.; Bernardi, N.; Colaço, M.; Borges, O.
Source: check_circle
CIÊNCIAVITAE

Polyester Nanoparticle Immunotoxicological Profile

SPI XLV Annual Meeting
2019-05 | Conference poster
SOURCE-WORK-ID:

cv-prod-id-1222799

Contributors: Jesus, S.; Da Silva, J.; Bernardi, N.; Panão Costa, J.; Borges, O.
Source: check_circle
CIÊNCIAVITAE

Evaluation of immunotoxicological properties of PCL and PCL/glucan nanoparticles.

2nd SPLC-CRS Young Scientists Meeting, Santiago de Compostela, Spain.
2019-01-23 | Conference poster
SOURCE-WORK-ID:

cv-prod-id-437731

Contributors: Bernardi, N.; Jesus, S.; Da Silva, J.; Soares, E.; Borges, O.
Source: check_circle
CIÊNCIAVITAE