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China Medical University: Taichung, TW

2014-08-01 to present | Associate professor (Graduate Institute of Biomedical Sciences)
Employment
Source: Self-asserted source
Ru-Huei Fu

China Medical University: Taichung, TW

2009-02-01 to 2014-07-31 | Assistant Professor (Graduate Institute of Immunology)
Employment
Source: Self-asserted source
Ru-Huei Fu

Education and qualifications (1)

National Taiwan University: Taipei, TW

1998-07-31 to 2003-07-31 | Ph. D (Department of Biochemical Science and Technology (BST))
Education
Source: Self-asserted source
Ru-Huei Fu

Works (50 of 55)

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Page 1 of 2

Pectolinarigenin Improves Oxidative Stress and Apoptosis in Mouse NSC-34 Motor Neuron Cell Lines Induced by C9-ALS-Associated Proline–Arginine Dipeptide Repeat Proteins by Enhancing Mitochondrial Fusion Mediated via the SIRT3/OPA1 Axis

Antioxidants
2023-11 | Journal article | Author
DOI: 10.3390/antiox12112008
Contributors: Ru-Huei Fu
Source: check_circle
Multidisciplinary Digital Publishing Institute

Glycine-Alanine Dipeptide Repeat Protein from C9-ALS Interacts with Sulfide Quinone Oxidoreductase (SQOR) to Induce the Activity of the NLRP3 Inflammasome in HMC3 Microglia: Irisflorentin Reverses This Interaction

Antioxidants
2023-10 | Journal article | Author
DOI: 10.3390/antiox12101896
Contributors: Ru-Huei Fu; Hui-Jye Chen; Syuan-Yu Hong
Source: check_circle
Multidisciplinary Digital Publishing Institute

Interaction of the <i>C9orf72</i>-Amyotrophic Lateral Sclerosis-Related Proline–Arginine Dipeptide Repeat Protein with the RNA-Binding Protein NOVA1 Causes Decreased Expression of UNC13A Due to Enhanced Inclusion of Cryptic Exons, Which Is Reversed by Betulin Treatment

Cells
2023-10 | Journal article | Author
DOI: 10.3390/cells12202476
Contributors: Ru-Huei Fu; Hui-Jye Chen; Syuan-Yu Hong
Source: check_circle
Multidisciplinary Digital Publishing Institute

Chiisanoside Mediates the Parkin/ZNF746/PGC-1α Axis by Downregulating MiR-181a to Improve Mitochondrial Biogenesis in 6-OHDA-Caused Neurotoxicity Models In Vitro and In Vivo: Suggestions for Prevention of Parkinson’s Disease

Antioxidants
2023-09 | Journal article | Author
DOI: 10.3390/antiox12091782
Contributors: Yu-Ling Hsu; Hui-Jye Chen; Jia-Xin Gao; Ming-Yang Yang; Ru-Huei Fu
Source: check_circle
Multidisciplinary Digital Publishing Institute

Syringin Prevents 6-Hydroxydopamine Neurotoxicity by Mediating the MiR-34a/SIRT1/Beclin-1 Pathway and Activating Autophagy in SH-SY5Y Cells and the <i>Caenorhabditis elegans</i> Model

Cells
2023-09 | Journal article | Author
DOI: 10.3390/cells12182310
Contributors: Ru-Huei Fu; Syuan-Yu Hong; Hui-Jye Chen
Source: check_circle
Multidisciplinary Digital Publishing Institute

Interaction of a Novel Alternatively Spliced Variant of <i>HSD11B1L</i> with Parkin Enhances the Carcinogenesis Potential of Glioblastoma: Peiminine Interferes with This Interaction

Cells
2023-03 | Journal article | Author
DOI: 10.3390/cells12060894
Contributors: Ru-Huei Fu; Syuan-Yu Hong; Chia-Wen Tsai; Shih-Ping Liu; Shao-Chih Chiu; Meng-Zhen Wu; Woei-Cherng Shyu; Shinn-Zong Lin
Source: check_circle
Multidisciplinary Digital Publishing Institute

C9-ALS-Associated Proline-Arginine Dipeptide Repeat Protein Induces Activation of NLRP3 Inflammasome of HMC3 Microglia Cells by Binding of Complement Component 1 Q Subcomponent-Binding Protein (C1QBP), and Syringin Prevents This Effect

Cells
2022-10 | Journal article | Author
DOI: 10.3390/cells11193128
Contributors: Ru-Huei Fu; Chia-Wen Tsai; Shao-Chih Chiu; Shih-Ping Liu; Yu-Ting Chiang; Yun-Hua Kuo; Woei-Cherng Shyu; Shinn-Zong Lin
Source: check_circle
Multidisciplinary Digital Publishing Institute

Neuroprotective Capability of Narcissoside in 6-OHDA-Exposed Parkinson’s Disease Models through Enhancing the MiR200a/Nrf-2/GSH Axis and Mediating MAPK/Akt Associated Signaling Pathway

Antioxidants
2022-10 | Journal article | Author
DOI: 10.3390/antiox11112089
Contributors: Ru-Huei Fu; Chia-Wen Tsai; Shih-Ping Liu; Shao-Chih Chiu; Yen-Chuan Chen; Yu-Ting Chiang; Yun-Hua Kuo; Woei-Cherng Shyu; Shinn-Zong Lin
Source: check_circle
Multidisciplinary Digital Publishing Institute

A Novel Splice Variant of <i>BCAS1</i> Inhibits β-Arrestin 2 to Promote the Proliferation and Migration of Glioblastoma Cells, and This Effect Was Blocked by Maackiain

Cancers
2022-08 | Journal article | Author
DOI: 10.3390/cancers14163890
Contributors: Yun-Hua Kuo; Huey-Shan Hung; Chia-Wen Tsai; Shao-Chih Chiu; Shih-Ping Liu; Yu-Ting Chiang; Woei-Cherng Shyu; Shinn-Zong Lin; Ru-Huei Fu
Source: check_circle
Multidisciplinary Digital Publishing Institute

Delivery Capacity and Anticancer Ability of the Berberine-Loaded Gold Nanoparticles to Promote the Apoptosis Effect in Breast Cancer

Cancers
2021-10 | Journal article | Author
DOI: 10.3390/cancers13215317
Contributors: Chen-Feng Chiu; Ru-Huei Fu; Shan-hui Hsu; Yang-Hao (Alex) Yu; Shun-Fa Yang; Thomas Chang-Yao Tsao; Kai-Bo Chang; Chun-An Yeh; Cheng-Ming Tang; Sheng-Chu Huang et al.
Source: check_circle
Multidisciplinary Digital Publishing Institute

The novel application of cordycepin in maintaining stem cell pluripotency and increasing iPS cell generation efficiency

Scientific Reports
2020-12 | Journal article
DOI: 10.1038/s41598-020-59154-5
Part of ISSN: 2045-2322
Source: Self-asserted source
Ru-Huei Fu

Upregulation of OPA1 by carnosic acid is mediated through induction of IKKγ ubiquitination by parkin and protects against neurotoxicity

Food and Chemical Toxicology
2020-02 | Journal article
DOI: 10.1016/j.fct.2019.110942
Part of ISSN: 0278-6915
Source: Self-asserted source
Ru-Huei Fu

Deficiency or activation of peroxisome proliferator-activated receptor α reduces the tissue concentrations of endogenously synthesized docosahexaenoic acid in C57BL/6J mice

Nutrition Research and Practice
2019 | Journal article
DOI: 10.4162/nrp.2019.13.4.286
Part of ISSN: 1976-1457
Part of ISSN: 2005-6168
Source: Self-asserted source
Ru-Huei Fu

Recombinant Aflatoxin-Degrading F420H2-Dependent Reductase from Mycobacterium smegmatis Protects Mammalian Cells from Aflatoxin Toxicity

Toxins
2019-05-08 | Journal article
DOI: 10.3390/toxins11050259
Part of ISSN: 2072-6651
Source: Self-asserted source
Ru-Huei Fu
grade
Preferred source (of 2)‎

Adipose-derived Stem Cells Stimulated with n-Butylidenephthalide Exhibit Therapeutic Effects in a Mouse Model of Parkinson’s Disease

Cell Transplantation
2018-03 | Journal article
DOI: 10.1177/0963689718757408
Part of ISSN: 0963-6897
Part of ISSN: 1555-3892
Source: Self-asserted source
Ru-Huei Fu

Increase of Meningitis Risk in Stroke Patients in Taiwan

Frontiers in Neurology
2018-03-02 | Journal article
DOI: 10.3389/fneur.2018.00116
Part of ISSN: 1664-2295
Source: Self-asserted source
Ru-Huei Fu

A PEG-Based Hydrogel for Effective Wound Care Management

Cell Transplantation
2018-02 | Journal article
DOI: 10.1177/0963689717749032
Part of ISSN: 0963-6897
Part of ISSN: 1555-3892
Source: Self-asserted source
Ru-Huei Fu

Modulation of ARTS and XIAP by Parkin Is Associated with Carnosic Acid Protects SH-SY5Y Cells against 6-Hydroxydopamine-Induced Apoptosis

Molecular Neurobiology
2018-02 | Journal article
DOI: 10.1007/s12035-017-0443-4
Part of ISSN: 0893-7648
Part of ISSN: 1559-1182
Source: Self-asserted source
Ru-Huei Fu

Neuroprotective Effects of Betulin in Pharmacological and TransgenicCaenorhabditis elegansModels of Parkinson’s Disease

Cell Transplantation
2017-12 | Journal article
DOI: 10.1177/0963689717738785
Part of ISSN: 0963-6897
Part of ISSN: 1555-3892
Source: Self-asserted source
Ru-Huei Fu

Inhibition of JNK by pi class of glutathione S -transferase through PKA/CREB pathway is associated with carnosic acid protection against 6-hydroxydopamine-induced apoptosis

Food and Chemical Toxicology
2017-05 | Journal article
DOI: 10.1016/j.fct.2017.03.020
Part of ISSN: 0278-6915
Source: Self-asserted source
Ru-Huei Fu

Prominent Vascularization Capacity of Mesenchymal Stem Cells in Collagen–Gold Nanocomposites

ACS Applied Materials & Interfaces
2016-10-26 | Journal article
DOI: 10.1021/acsami.6b09330
Part of ISSN: 1944-8244
Part of ISSN: 1944-8252
Source: Self-asserted source
Ru-Huei Fu

Therapeutic Effect of Ligustilide-Stimulated Adipose-Derived Stem Cells in a Mouse Thromboembolic Stroke Model

Cell Transplantation
2016-05 | Journal article
DOI: 10.3727/096368916x690539
Part of ISSN: 0963-6897
Part of ISSN: 1555-3892
Source: Self-asserted source
Ru-Huei Fu

Electrospun Polyacrylonitrile-Based Nanofibers Maintain Embryonic Stem Cell Stemness via TGF-Beta Signaling

Journal of Biomedical Nanotechnology
2016-04-01 | Journal article
DOI: 10.1166/jbn.2016.2201
Part of ISSN: 1550-7033
Source: Self-asserted source
Ru-Huei Fu

Plasma L5 levels are elevated in ischemic stroke patients and enhance platelet aggregation

Blood
2016-03-10 | Journal article
DOI: 10.1182/blood-2015-05-646117
Part of ISSN: 0006-4971
Part of ISSN: 1528-0020
Source: Self-asserted source
Ru-Huei Fu

Applicability of Adipose-Derived Stem Cells in Type 1 Diabetes Mellitus

Cell Transplantation
2015-03 | Journal article
DOI: 10.3727/096368915x686977
Part of ISSN: 0963-6897
Part of ISSN: 1555-3892
Source: Self-asserted source
Ru-Huei Fu

Differentiation of Embryonic Stem Cells into Cardiomyocytes Used to Investigate the Cardioprotective Effect of Salvianolic Acid B through BNIP3 Involved Pathway

Cell Transplantation
2015-03 | Journal article
DOI: 10.3727/096368915x686995
Part of ISSN: 0963-6897
Part of ISSN: 1555-3892
Source: Self-asserted source
Ru-Huei Fu

Irisflorentin Modifies Properties of Mouse Bone Marrow-Derived Dendritic Cells and Reduces the Allergic Contact Hypersensitivity Responses

Cell Transplantation
2015-03 | Journal article
DOI: 10.3727/096368915x687002
Part of ISSN: 0963-6897
Part of ISSN: 1555-3892
Source: Self-asserted source
Ru-Huei Fu

Induction of Pi Form of GlutathioneS-Transferase by Carnosic Acid Is Mediated through PI3K/Akt/NF-κB Pathway and Protects against Neurotoxicity

Chemical Research in Toxicology
2014-11-17 | Journal article
DOI: 10.1021/tx5003063
Part of ISSN: 0893-228X
Part of ISSN: 1520-5010
Source: Self-asserted source
Ru-Huei Fu

Regulation of human endothelial progenitor cell maturation by polyurethane nanocomposites

Biomaterials
2014-08 | Journal article
DOI: 10.1016/j.biomaterials.2014.04.076
Part of ISSN: 0142-9612
Source: Self-asserted source
Ru-Huei Fu

Involvement of the Carboxyl-Terminal Region of the Yeast Peroxisomal Half ABC Transporter Pxa2p in Its Interaction with Pxa1p and in Transporter Function

PLoS ONE
2014-08-13 | Journal article
DOI: 10.1371/journal.pone.0104892
Part of ISSN: 1932-6203
Source: Self-asserted source
Ru-Huei Fu

Acetylcorynoline attenuates dopaminergic neuron degeneration and α-synuclein aggregation in animal models of Parkinson's disease

Neuropharmacology
2014-07 | Journal article
DOI: 10.1016/j.neuropharm.2013.08.007
Part of ISSN: 0028-3908
Source: Self-asserted source
Ru-Huei Fu

Decellularization and Recellularization Technologies in Tissue Engineering

Cell Transplantation
2014-05 | Journal article
DOI: 10.3727/096368914x678382
Part of ISSN: 0963-6897
Part of ISSN: 1555-3892
Source: Self-asserted source
Ru-Huei Fu

Dryocrassin Suppresses Immunostimulatory Function of Dendritic Cells and Prolongs Skin Allograft Survival

Cell Transplantation
2014-05 | Journal article
DOI: 10.3727/096368914x678373
Part of ISSN: 0963-6897
Part of ISSN: 1555-3892
Source: Self-asserted source
Ru-Huei Fu

Salvianolic Acid B Maintained Stem Cell Pluripotency and Increased Proliferation Rate by Activating Jak2–Stat3 Combined with EGFR–Erk1/2 Pathways

Cell Transplantation
2014-05 | Journal article
DOI: 10.3727/096368914x678391
Part of ISSN: 0963-6897
Part of ISSN: 1555-3892
Source: Self-asserted source
Ru-Huei Fu

Therapeutic Potential of MicroRNA Let-7: Tumor Suppression or Impeding Normal Stemness

Cell Transplantation
2014-05 | Journal article
DOI: 10.3727/096368914x678418
Part of ISSN: 0963-6897
Part of ISSN: 1555-3892
Source: Self-asserted source
Ru-Huei Fu

Mouse-Induced Pluripotent Stem Cells Generated Under Hypoxic Conditions in the Absence of Viral Infection and Oncogenic Factors and Used for Ischemic Stroke Therapy

Stem Cells and Development
2014-02-15 | Journal article
DOI: 10.1089/scd.2013.0182
Part of ISSN: 1547-3287
Part of ISSN: 1557-8534
Source: Self-asserted source
Ru-Huei Fu

n-Butylidenephthalide Protects against Dopaminergic Neuron Degeneration and α-Synuclein Accumulation in Caenorhabditis elegans Models of Parkinson's Disease

PLoS ONE
2014-01-08 | Journal article
DOI: 10.1371/journal.pone.0085305
Part of ISSN: 1932-6203
Source: Self-asserted source
Ru-Huei Fu

Aberrant Alternative Splicing Events in Parkinson's Disease

Cell Transplantation
2013-04 | Journal article
DOI: 10.3727/096368912x655154
Part of ISSN: 0963-6897
Part of ISSN: 1555-3892
Source: Self-asserted source
Ru-Huei Fu

Adipose-Derived Stem Cells: Isolation, Characterization, and Differentiation Potential

Cell Transplantation
2013-04 | Journal article
DOI: 10.3727/096368912x655127
Part of ISSN: 0963-6897
Part of ISSN: 1555-3892
Source: Self-asserted source
Ru-Huei Fu

Stem Cell Applications in Regenerative Medicine for Neurological Disorders

Cell Transplantation
2013-04 | Journal article
DOI: 10.3727/096368912x655145
Part of ISSN: 0963-6897
Part of ISSN: 1555-3892
Source: Self-asserted source
Ru-Huei Fu

Acetylcorynoline Impairs the Maturation of Mouse Bone Marrow-Derived Dendritic Cells via Suppression of IκB Kinase and Mitogen-Activated Protein Kinase Activities

PLoS ONE
2013-03-05 | Journal article
DOI: 10.1371/journal.pone.0058398
Part of ISSN: 1932-6203
Source: Self-asserted source
Ru-Huei Fu

Myricetin attenuates lipopolysaccharide-stimulated activation of mouse bone marrow-derived dendritic cells through suppression of IKK/NF-κB and MAPK signalling pathways

Journal of the Science of Food and Agriculture
2013-01-15 | Journal article
DOI: 10.1002/jsfa.5733
Part of ISSN: 0022-5142
Source: Self-asserted source
Ru-Huei Fu

n-Butylidenephthalide (BP) Maintains Stem Cell Pluripotency by Activating Jak2/Stat3 Pathway and Increases the Efficiency of iPS Cells Generation

PLoS ONE
2012-09-07 | Journal article
DOI: 10.1371/journal.pone.0044024
Part of ISSN: 1932-6203
Source: Self-asserted source
Ru-Huei Fu

Lipopolysaccharide-stimulated activation of murine DC2.4 cells is attenuated by n-butylidenephthalide through suppression of the NF-κB pathway

Biotechnology Letters
2011-05 | Journal article
DOI: 10.1007/s10529-011-0528-5
Part of ISSN: 0141-5492
Part of ISSN: 1573-6776
Source: Self-asserted source
Ru-Huei Fu

Differentiation of Stem Cells: Strategies for Modifying Surface Biomaterials

Cell Transplantation
2011-02 | Journal article
DOI: 10.3727/096368910x532756
Part of ISSN: 0963-6897
Part of ISSN: 1555-3892
Source: Self-asserted source
Ru-Huei Fu

Induced Pluripotent Stem (iPS) Cell Research Overview

Cell Transplantation
2011-02 | Journal article
DOI: 10.3727/096368910x532828
Part of ISSN: 0963-6897
Part of ISSN: 1555-3892
Source: Self-asserted source
Ru-Huei Fu

Spatial control of cells, peptide delivery and dynamic monitoring of cellular physiology with chitosan-assisted dual color quantum dot FRET peptides

Acta Biomaterialia
2010-09 | Journal article
DOI: 10.1016/j.actbio.2010.03.005
Part of ISSN: 1742-7061
Source: Self-asserted source
Ru-Huei Fu

Alternative Splicing Modulates Stem Cell Differentiation

Cell Transplantation
2009-09 | Journal article
DOI: 10.3727/096368909x471260
Part of ISSN: 0963-6897
Part of ISSN: 1555-3892
Source: Self-asserted source
Ru-Huei Fu

MicroRNAs Regulation Modulated Self-Renewal and Lineage Differentiation of Stem Cells

Cell Transplantation
2009-09 | Journal article
DOI: 10.3727/096368909x471224
Part of ISSN: 0963-6897
Part of ISSN: 1555-3892
Source: Self-asserted source
Ru-Huei Fu

CPAP is a cell-cycle regulated protein that controls centriole length

Nature Cell Biology
2009-07 | Journal article
DOI: 10.1038/ncb1889
Part of ISSN: 1465-7392
Part of ISSN: 1476-4679
Source: Self-asserted source
Ru-Huei Fu
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