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Cancer Immunology, Cancer Immunotherapy, Cancer Biology

Activities

Works (44)

An immunomechanical checkpoint PYK2 governs monocyte-to-macrophage differentiation in pancreatic cancer

BioRxiv
2024 | Journal article
Contributors: Xie, W.; Yu, X.; Yang, Q.; Ke, N.; Wang, P.; Kong, H.; Wu, X.; Ma, P.; Chen, L.; Yang, J. et al.
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Multi-modal profiling identifies CD4+CXCR5+PD-1- Tfh cells as prognostic and predictive biomarkers for response to R-CHOP therapy in human DLBCL

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Nuclear FAK aggravates CD8+ T cell exhaustion via the SP1-IL-6 axis in colorectal cancer

BioRxiv
2024 | Journal article
Contributors: Kong, Hao; Wu, Xiangji; Yang, Qingxin; Wu, Chunwei; Yu, Xin; Yang, Jie; Xie, Dai; Dai, Yu; Chen, Lang; Ma, Panpan et al.
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Data from Spatial Context of Immune Checkpoints as Predictors of Overall Survival in Patients with Resectable Colorectal Cancer Independent of Standard Tumor–Node–Metastasis Stages

2024-11-26 | Preprint
Contributors: Hao Kong; Qingxin Yang; Chunwei Wu; Xiangji Wu; Xinrui Yan; Li-Bin Huang; Lu Chen; Zong-Guang Zhou; Ping Wang; Hong Jiang
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Figure 1 from Spatial Context of Immune Checkpoints as Predictors of Overall Survival in Patients with Resectable Colorectal Cancer Independent of Standard Tumor–Node–Metastasis Stages

2024-11-26 | Preprint
Contributors: Hao Kong; Qingxin Yang; Chunwei Wu; Xiangji Wu; Xinrui Yan; Li-Bin Huang; Lu Chen; Zong-Guang Zhou; Ping Wang; Hong Jiang
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Figure 2 from Spatial Context of Immune Checkpoints as Predictors of Overall Survival in Patients with Resectable Colorectal Cancer Independent of Standard Tumor–Node–Metastasis Stages

2024-11-26 | Preprint
Contributors: Hao Kong; Qingxin Yang; Chunwei Wu; Xiangji Wu; Xinrui Yan; Li-Bin Huang; Lu Chen; Zong-Guang Zhou; Ping Wang; Hong Jiang
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Figure 3 from Spatial Context of Immune Checkpoints as Predictors of Overall Survival in Patients with Resectable Colorectal Cancer Independent of Standard Tumor–Node–Metastasis Stages

2024-11-26 | Preprint
Contributors: Hao Kong; Qingxin Yang; Chunwei Wu; Xiangji Wu; Xinrui Yan; Li-Bin Huang; Lu Chen; Zong-Guang Zhou; Ping Wang; Hong Jiang
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Figure 4 from Spatial Context of Immune Checkpoints as Predictors of Overall Survival in Patients with Resectable Colorectal Cancer Independent of Standard Tumor–Node–Metastasis Stages

2024-11-26 | Preprint
Contributors: Hao Kong; Qingxin Yang; Chunwei Wu; Xiangji Wu; Xinrui Yan; Li-Bin Huang; Lu Chen; Zong-Guang Zhou; Ping Wang; Hong Jiang
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Figure S1 from Spatial Context of Immune Checkpoints as Predictors of Overall Survival in Patients with Resectable Colorectal Cancer Independent of Standard Tumor–Node–Metastasis Stages

2024-11-26 | Preprint
Contributors: Hao Kong; Qingxin Yang; Chunwei Wu; Xiangji Wu; Xinrui Yan; Li-Bin Huang; Lu Chen; Zong-Guang Zhou; Ping Wang; Hong Jiang
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Figure S2 from Spatial Context of Immune Checkpoints as Predictors of Overall Survival in Patients with Resectable Colorectal Cancer Independent of Standard Tumor–Node–Metastasis Stages

2024-11-26 | Preprint
Contributors: Hao Kong; Qingxin Yang; Chunwei Wu; Xiangji Wu; Xinrui Yan; Li-Bin Huang; Lu Chen; Zong-Guang Zhou; Ping Wang; Hong Jiang
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Figure S3 from Spatial Context of Immune Checkpoints as Predictors of Overall Survival in Patients with Resectable Colorectal Cancer Independent of Standard Tumor–Node–Metastasis Stages

2024-11-26 | Preprint
Contributors: Hao Kong; Qingxin Yang; Chunwei Wu; Xiangji Wu; Xinrui Yan; Li-Bin Huang; Lu Chen; Zong-Guang Zhou; Ping Wang; Hong Jiang
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Figure S4 from Spatial Context of Immune Checkpoints as Predictors of Overall Survival in Patients with Resectable Colorectal Cancer Independent of Standard Tumor–Node–Metastasis Stages

2024-11-26 | Preprint
Contributors: Hao Kong; Qingxin Yang; Chunwei Wu; Xiangji Wu; Xinrui Yan; Li-Bin Huang; Lu Chen; Zong-Guang Zhou; Ping Wang; Hong Jiang
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Figure S5 from Spatial Context of Immune Checkpoints as Predictors of Overall Survival in Patients with Resectable Colorectal Cancer Independent of Standard Tumor–Node–Metastasis Stages

2024-11-26 | Preprint
Contributors: Hao Kong; Qingxin Yang; Chunwei Wu; Xiangji Wu; Xinrui Yan; Li-Bin Huang; Lu Chen; Zong-Guang Zhou; Ping Wang; Hong Jiang
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Figure S6 from Spatial Context of Immune Checkpoints as Predictors of Overall Survival in Patients with Resectable Colorectal Cancer Independent of Standard Tumor–Node–Metastasis Stages

2024-11-26 | Preprint
Contributors: Hao Kong; Qingxin Yang; Chunwei Wu; Xiangji Wu; Xinrui Yan; Li-Bin Huang; Lu Chen; Zong-Guang Zhou; Ping Wang; Hong Jiang
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Table S1 from Spatial Context of Immune Checkpoints as Predictors of Overall Survival in Patients with Resectable Colorectal Cancer Independent of Standard Tumor–Node–Metastasis Stages

2024-11-26 | Preprint
Contributors: Hao Kong; Qingxin Yang; Chunwei Wu; Xiangji Wu; Xinrui Yan; Li-Bin Huang; Lu Chen; Zong-Guang Zhou; Ping Wang; Hong Jiang
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Table S2 from Spatial Context of Immune Checkpoints as Predictors of Overall Survival in Patients with Resectable Colorectal Cancer Independent of Standard Tumor–Node–Metastasis Stages

2024-11-26 | Preprint
Contributors: Hao Kong; Qingxin Yang; Chunwei Wu; Xiangji Wu; Xinrui Yan; Li-Bin Huang; Lu Chen; Zong-Guang Zhou; Ping Wang; Hong Jiang
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Table S3 from Spatial Context of Immune Checkpoints as Predictors of Overall Survival in Patients with Resectable Colorectal Cancer Independent of Standard Tumor–Node–Metastasis Stages

2024-11-26 | Preprint
Contributors: Hao Kong; Qingxin Yang; Chunwei Wu; Xiangji Wu; Xinrui Yan; Li-Bin Huang; Lu Chen; Zong-Guang Zhou; Ping Wang; Hong Jiang
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Table S4 from Spatial Context of Immune Checkpoints as Predictors of Overall Survival in Patients with Resectable Colorectal Cancer Independent of Standard Tumor–Node–Metastasis Stages

2024-11-26 | Preprint
Contributors: Hao Kong; Qingxin Yang; Chunwei Wu; Xiangji Wu; Xinrui Yan; Li-Bin Huang; Lu Chen; Zong-Guang Zhou; Ping Wang; Hong Jiang
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Table S5 from Spatial Context of Immune Checkpoints as Predictors of Overall Survival in Patients with Resectable Colorectal Cancer Independent of Standard Tumor–Node–Metastasis Stages

2024-11-26 | Preprint
Contributors: Hao Kong; Qingxin Yang; Chunwei Wu; Xiangji Wu; Xinrui Yan; Li-Bin Huang; Lu Chen; Zong-Guang Zhou; Ping Wang; Hong Jiang
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Spatial Context of Immune Checkpoints as Predictors of Overall Survival in Patients with Resectable Colorectal Cancer Independent of Standard Tumor–Node–Metastasis Stages

Cancer Research Communications
2024-11-01 | Journal article
Contributors: Hao Kong; Qingxin Yang; Chunwei Wu; Xiangji Wu; Xinrui Yan; Li-Bin Huang; Lu Chen; Zong-Guang Zhou; Ping Wang; Hong Jiang
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Receptor-interacting protein kinase 2 is an immunotherapy target in pancreatic cancer.

Cancer discovery
2023-10-12 | Journal article | Author
Contributors: Wenhua Sang; Yiduo Zhou; Haiyan Chen; Chengxuan Yu; dai lisi; Zhongkun Liu; Lang Chen; Yimin Fang; Panpan Ma; Xiangji Wu et al.
Source: Self-asserted source
Hong Jiang
grade
Preferred source (of 2)‎

Liquid-in-liquid printing of 3D and mechanically tunable conductive hydrogels

Nature Communications
2023-07-18 | Journal article
Contributors: Xinjian Xie; Zhonggang Xu; Xin Yu; Hong Jiang; Hongjiao Li; Wenqian Feng
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Crossref
grade
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Static and Dynamic: Evolving Biomaterial Mechanical Properties to Control Cellular Mechanotransduction.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
2023-01-19 | Journal article
Contributors: Xie W; Wei X; Kang H; Jiang H; Chu Z; Lin Y; wenyan xie; Wei Q
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Hong Jiang
grade
Preferred source (of 2)‎

Pan-cancer single-cell analysis reveals the heterogeneity and plasticity of cancer-associated fibroblasts in the tumor microenvironment

2022 | Journal article
Contributors: Hong Jiang
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Hong Jiang
grade
Preferred source (of 2)‎

Stromal architecture directs early dissemination in pancreatic ductal

JCI Insight
2022 | Journal article
Contributors: Ray, Arja; Callaway, Mackenzie K.; Rodriguez-Merced, Nelson J.; Crampton, Alexandra L.; Carlson, Marjorie; Emme, Kenneth B.; Ensminger, Ethan A.; Kinne, Alexander A.; Schrope, Jonathan H.; Rasmussen, Haley R. et al.
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Development of resistance to FAK inhibition in pancreatic cancer is linked to stromal depletion

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Hong Jiang
grade
Preferred source (of 2)‎

Tumor-associated fibrosis as a regulator of tumor immunity and response to immunotherapy

Cancer Immunology, Immunotherapy
2017 | Journal article
Contributors: Jiang, Hong; Hegde, Samarth; DeNardo, David G.
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Targeting focal adhesion kinase renders pancreatic cancers responsive to checkpoint immunotherapy

Nature Medicine
2016 | Journal article
Source: Self-asserted source
Hong Jiang
grade
Preferred source (of 2)‎

A review: Using nanoparticles to enhance absorption and bioavailability of phenolic phytochemicals

Food Hydrocolloids
2015 | Journal article
Contributors: Li, Zheng; Jiang, Hong; Xu, Changmou; Gu, Liwei
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Intercellular transfer of messenger RNAs in multiorgan tumorigenesis by tumor cell-derived exosomes

Molecular Medicine Reports
2015 | Journal article
Contributors: Jiang, Hong; Li, Zheng; Li, Xiaohua; Xia, Jianguo
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Interspecies communication between plant and mouse gut host cells through edible plant derived exosome-like nanoparticles

Molecular Nutrition and Food Research
2014 | Journal article
Contributors: Mu, Jingyao; Zhuang, Xiaoying; Wang, Qilong; Jiang, Hong; Deng, Zhong-Bin; Wang, Baomei; Zhang, Lifeng; Kakar, Sham; Jun, Yan; Miller, Donald et al.
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Quantitatively Controlling Expression of miR-17∼92 Determines Colon Tumor Progression in a Mouse Tumor Model

The American Journal of Pathology
2014 | Journal article
Contributors: Jiang, Hong; Wang, Ping; Wang, Qilong; Wang, Baomei; Mu, Jingyao; Zhuang, Xiaoying; Zhang, Lifeng; Yan, Jun; Miller, Donald; Zhang, Huang-Ge
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Restoration of miR17/20a in Solid Tumor Cells Enhances the Natural Killer Cell Antitumor Activity by Targeting Mekk2

Cancer Immunology Research
2014 | Journal article
Contributors: Jiang, Hong; Wang, Ping; Li, Xiaohua; Wang, Qilong; Deng, Zhong-Bin; Zhuang, Xiaoying; Mu, Jingyao; Zhang, Lifeng; Wang, Baomei; Yan, Jun et al.
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Targeted Drug Delivery to Intestinal Macrophages by Bioactive Nanovesicles Released from Grapefruit

Molecular Therapy
2014 | Journal article
Contributors: Wang, Baomei; Zhuang, Xiaoying; Deng, Zhong-Bin; Jiang, Hong; Mu, Jingyao; Wang, Qilong; Xiang, Xiaoyu; Guo, Haixun; Zhang, Lifeng; Dryden, Gerald et al.
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Delivery of therapeutic agents by nanoparticles made of grapefruit-derived lipids

Nature Communications
2013 | Journal article
Contributors: Wang, Qilong; Zhuang, Xiaoying; Mu, Jingyao; Deng, Zhong-Bin; Jiang, Hong; Xiang, Xiaoyu; Wang, Baomei; Yan, Jun; Miller, Donald; Zhang, Huang-Ge
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Exosome-like Nanoparticles from Intestinal Mucosal Cells Carry Prostaglandin E<sub>2</sub> and Suppress Activation of Liver NKT Cells

The Journal of Immunology
2013 | Journal article
Contributors: Deng, Zhong-Bin; Zhuang, Xiaoying; Ju, Songwen; Xiang, Xiaoyu; Mu, Jingyao; Liu, Yuelong; Jiang, Hong; Zhang, Lifeng; Mobley, James; McClain, Craig et al.
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Grape Exosome-like Nanoparticles Induce Intestinal Stem Cells and Protect Mice From DSS-Induced Colitis

Molecular Therapy
2013 | Journal article
Contributors: Ju, Songwen; Mu, Jingyao; Dokland, Terje; Zhuang, Xiaoying; Wang, Qilong; Jiang, Hong; Xiang, Xiaoyu; Deng, Zhong-Bin; Wang, Baomei; Zhang, Lifeng et al.
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Intestinal mucus-derived nanoparticle-mediated activation of Wnt/β-catenin signaling plays a role in induction of liver natural killer T cell anergy in mice

Hepatology
2013 | Journal article
Contributors: Deng, Zhong-Bin; Zhuang, Xiaoying; Ju, Songwen; Xiang, Xiaoyu; Mu, Jingyao; Wang, Qilong; Jiang, Hong; Zhang, Lifeng; Kronenberg, Mitchell; Yan, Jun et al.
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Grhl2 Determines the Epithelial Phenotype of Breast Cancers and Promotes Tumor Progression

Plos One
2012 | Journal article
Contributors: Xiang, Xiaoyu; Deng, ZhongBin; Zhuang, Xiaoying; Ju, Songwen; Mu, Jingyao; Jiang, Hong; Zhang, Lifeng; Yan, Jun; Miller, Donald; Zhang, Huang-Ge
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Tumor Cell Cross Talk with Tumor-Associated Leukocytes Leads to Induction of Tumor Exosomal Fibronectin and Promotes Tumor Progression

The American Journal of Pathology
2012 | Journal article
Contributors: Deng, ZhongBin; Cheng, Ziqiang; Xiang, Xiaoyu; Yan, Jun; Zhuang, Xiaoying; Liu, Cunren; Jiang, Hong; Ju, Songwen; Zhang, Lifeng; Grizzle, William et al.
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Exosomes Derived from Immature Bone Marrow Dendritic Cells Induce Tolerogenicity of Intestinal Transplantation in Rats

Journal of Surgical Research
2011 | Journal article
Contributors: Yang, Xiaojun; Meng, Song; Jiang, Hong; Zhu, Chunfu; Wu, Wenxi
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miR-155 promotes macroscopic tumor formation yet inhibits tumor dissemination from mammary fat pads to the lung by preventing EMT

Oncogene
2011 | Journal article
Contributors: Xiang, X.; Zhuang, X.; Ju, S.; Zhang, S.; Jiang, H.; Mu, J.; Zhang, L.; Miller, D.; Grizzle, W.; Zhang, H-G
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Exosomes derived from interleukin-10-treated dendritic cells can inhibit trinitrobenzene sulfonic acid-induced rat colitis

Scandinavian Journal of Gastroenterology
2010 | Journal article
Contributors: Yang, Xiaojun; Meng, Song; Jiang, Hong; Chen, Tao; Wu, Wenxi
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Short hairpin RNA targeting β-catenin suppresses cell proliferation and induces apoptosis in human gastric carcinoma cells

Scandinavian Journal of Gastroenterology
2009 | Journal article
Contributors: Jiang, Hong; Xia, Jianguo; Kang, Jian; Ding, Yongbin; Wu, Wenxi
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Peer review (2 reviews for 1 publication/grant)

Review activity for Science China. (2)