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Employment (2)

The Jackson Laboratory: Bar Harbor, ME, US

2021-10 to present | Postdoctoral Fellow
Employment
Source: Self-asserted source
Michael MacLean

NYU Sackler Institute: NY, US

2021-08-07 | Graduate Student - Ph.D. (Cell Bio)
Employment
Source: Self-asserted source
Michael MacLean

Education and qualifications (2)

University of Maine: Orono, ME, US

B.S. in Biochemistry
Education
Source: Self-asserted source
Michael MacLean

New York University: New York, New York, US

2021-09 | PhD
Education
Source: Self-asserted source
Michael MacLean

Professional activities (3)

Association for Research in Vision and Ophthalmology: Rockville, Maryland, US

2023 to present
Membership
Source: Self-asserted source
Michael MacLean

Society for Neuroscience: Washington, US

2022 to present
Membership
Source: Self-asserted source
Michael MacLean

The New York Academy of Sciences: New York, NY, US

2017 to 2021-09-01
Membership
Source: Self-asserted source
Michael MacLean

Funding (2)

Training Program in Precision Genetics of Aging, Alzheimer's Disease and Related Dementias

2021-10 to 2023 | Grant
National Institute on Aging (Baltimore, Maryland, US)
URL: https://reporter.nih.gov/search/EaC3BhVN6USBfOMuTswDVQ/project-details/10142327
Part of GRANT_NUMBER:

5T32AG062409-02
Source: Self-asserted source
Michael MacLean

RAGE: A Potential Contributor to Neuroinflammation in Amyotrophic Lateral Sclerosis

2020-09-18 to 2021-09-17 | Grant
National Institute of Neurological Disorders and Stroke (Bethesda, US)
URL: https://app.dimensions.ai/details/grant/grant.9453440
GRANT_NUMBER: F31NS120424
Source: Self-asserted source
Michael MacLean via DimensionsWizard

Works (12)

Genetic context modulates aging and degeneration in the murine retina

Molecular Neurodegeneration
2025-01-20 | Journal article
DOI: 10.1186/s13024-025-00800-9
Contributors: Olivia J. Marola; Michael MacLean; Travis L. Cossette; Cory A. Diemler; Amanda A. Hewes; Alaina M. Reagan; Jonathan Nyandu Kanyinda; Daniel A. Skelly; Gareth R. Howell
Source: check_circle
Crossref
grade
Preferred source (of 3)‎

Microglia depletion leads to increased susceptibility to ocular hypertension-dependent glaucoma.

Frontiers in aging neuroscience
2024-07-02 | Journal article
DOI: 10.3389/fnagi.2024.1396443
DOI: 10.1101/2024.03.05.583529
PMID: 39015474
PMC: PMC11250491
Contributors: Diemler CA; MacLean M; Heuer SE; Hewes AA; Marola OJ; Libby RT; Howell GR
Source: Self-asserted source
Michael MacLean
grade
Preferred source (of 2)‎

IL1A enhances TNF-induced retinal ganglion cell death

BioRxiv
2024-06-01 | Preprint
DOI: 10.1101/2024.05.28.596328
Contributors: Katherine M Andersh; Michael MacLean; Gareth Howell; Richard T Libby
Source: Self-asserted source
Michael MacLean

New directions for Alzheimer's disease research from the Jackson Laboratory Center for Alzheimer's and Dementia Research 2022 workshop.

Alzheimer's & dementia (New York, N. Y.)
2024-01-01 | Journal article
DOI: 10.1002/trc2.12458
PMID: 38469553
PMC: PMC10925728
Contributors: Maria Telpoukhovskaia; Murdy TJ; Marola OJ; Charland K; MacLean M; Luquez T; Lish AM; Neuner S; Dunn A; Onos KD et al.
Source: Self-asserted source
Michael MacLean

Metabolic syndrome in New Zealand Obese mice promotes microglial-vascular interactions and reduces microglial plasticity

BioRxiv
2023-10-06 | Preprint
DOI: 10.1101/2023.10.04.560877
Contributors: Michael MacLean; Olivia J. Marola; Travis Cossette; Cory Diemler; Amanda A. Hewes; Kelly J. Keezer; Kristen D. Onos; Gareth Howell
Source: Self-asserted source
Michael MacLean

Neuronal–glial communication perturbations in murine SOD1G93A spinal cord

Communications Biology
2022-12 | Journal article
DOI: 10.1038/s42003-022-03128-y
Part of ISSN: 2399-3642
Source: Self-asserted source
Michael MacLean

Microglia RAGE exacerbates the progression of neurodegeneration within the SOD1G93A murine model of amyotrophic lateral sclerosis in a sex-dependent manner

Journal of Neuroinflammation
2021-06-15 | Journal article
DOI: 10.1186/s12974-021-02191-2
Part of ISSN: 1742-2094
Source: Self-asserted source
Michael MacLean

Inflammation Meets Metabolism: Roles for the Receptor for Advanced Glycation End Products Axis in Cardiovascular Disease

Immunometabolism
2021-06-02 | Journal article
DOI: 10.20900/immunometab20210024
Part of ISSN: 2633-0407
Source: Self-asserted source
Michael MacLean

A Receptor of the Immunoglobulin Superfamily Regulates Adaptive Thermogenesis.

Cell reports
2019-07-01 | Journal article
DOI: 10.1016/j.celrep.2019.06.061
PMID: 31315054
PMC: PMC6686683
Source: Self-asserted source
Michael MacLean

The Receptor for Advanced Glycation End Products (RAGE) and DIAPH1: Implications for vascular and neuroinflammatory dysfunction in disorders of the central nervous system.

Neurochemistry international
2019-03-20 | Journal article
DOI: 10.1016/j.neuint.2019.03.012
PMID: 30902646
Source: Self-asserted source
Michael MacLean

The Receptor for Advanced Glycation Endproducts (RAGE) and Mediation of Inflammatory Neurodegeneration.

Journal of Alzheimer's disease & Parkinsonism
2018-01-24 | Journal article
DOI: 10.4172/2161-0460.1000421
PMID: 30560011
PMC: PMC6293973
Source: Self-asserted source
Michael MacLean

The transmembrane domain of the p75 neurotrophin receptor stimulates phosphorylation of the TrkB tyrosine kinase receptor.

The Journal of biological chemistry
2017-08-17 | Journal article
DOI: 10.1074/jbc.M117.788729
PMID: 28821608
PMC: PMC5633122
Source: Self-asserted source
Michael MacLean
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