Personal information

Activities

Employment (6)

Chonnam National University Medical School: Hwasun, Hwasun, KR

2020-09-01 to present | Associate Professor (Medical Research Center)
Employment
Source: Self-asserted source
Yoonjoo Choi

MediMabBio: Sungnam, KR

2020-05-11 to 2020-08-31 | Principal Researcher
Employment
Source: Self-asserted source
Yoonjoo Choi

Seoul National University: Seoul, KR

2019-10-01 to 2020-04-30 | Assistant Research Professor (Statistics)
Employment
Source: Self-asserted source
Yoonjoo Choi

Korea Advanced Institute of Science and Technology: Daejeon, Daejeon, KR

2016-12-01 to 2019-09-30 | Research Assistant Professor (Biological Sciences)
Employment
Source: Self-asserted source
Yoonjoo Choi

Dartmouth College: Hanover, NH, US

2012-01-03 to 2016-09-30 | Research Associate (Computer Science)
Employment
Source: Self-asserted source
Yoonjoo Choi

Institute for Immunology and Informatics: Providence, RI, US

2012-01-03 to 2012-06-30
Employment
Source: Self-asserted source
Yoonjoo Choi

Education and qualifications (5)

University of Oxford: Oxford, Oxfordshire, GB

2007-10-09 to 2012-06-26 | DPhil (Statistics)
Education
Source: Self-asserted source
Yoonjoo Choi

King's College London: London, London, GB

2005-09-26 to 2006-11-01 | MSc (Mathematics)
Education
Source: Self-asserted source
Yoonjoo Choi

Sungkyunkwan University - Suwon Campus: Suwon, Gyeonggi-do, KR

1998-03-02 to 2005-02-25 | BSc (Physics)
Education
Source: Self-asserted source
Yoonjoo Choi

Sungkyunkwan University: Jongno-gu, Seoul, KR

1998-03-02 to 2005-02-25 | BA (Philosophy)
Education
Source: Self-asserted source
Yoonjoo Choi

Sungkyunkwan University: Jongno-gu, Seoul, KR

1998-03-02 to 2005-02-25 | BA (Chinese Philosophy)
Education
Source: Self-asserted source
Yoonjoo Choi

Funding (1)

계산적 방법을 이용한 단백질 치료제의 면역원성 제거 기술 개발

2016-12 to 2021-02 | Grant
National Research Foundation of Korea (Daejeon, KR)
GRANT_NUMBER:

2016H1D3A1938246

Source: Self-asserted source
Yoonjoo Choi

Works (39)

Positive Effects of Adiponectin, BDNF, and GLP-1 on Cortical Neurons Counteracting Palmitic Acid Induced Neurotoxicity

Clinical Nutrition Research
2024 | Journal article
Contributors: Danbi Jo; Seo Yeon Ahn; Seo Yoon Choi; Yoonjoo Choi; Dong Hoon Lee; Juhyun Song
Source: check_circle
Crossref

Benchmarking Sequence-Based and AlphaFold-Based Methods for pMHC-II Binding Core Prediction: Distinct Strengths and Consensus Approaches

2024-10-11 | Preprint
Contributors: Soobon Ko; Honglan Li; Hongeun Kim; Woong-Hee Shin; Junsu Ko; Yoonjoo Choi
Source: check_circle
Crossref

Assessing the predictive ability of computational epitope prediction methods on Fel d 1 and other allergens

PLOS ONE
2024-08-23 | Journal article
Contributors: Hyeji Kwon; Sheikh Arslan Sehgal; Soobon Ko; Kyungsoo Ha; Jungjoon K. Lee; Yoonjoo Choi
Source: check_circle
Crossref

Assessing the predictive ability of computational epitope prediction methods on Fel d 1 and other allergens

2023-06-05 | Preprint
Contributors: Hyeji Kwon; Soobon Ko; Kyungsoo Ha; Jungjoon K. Lee; Yoonjoo Choi
Source: check_circle
Crossref

A conformation-selective protein binder for a KRAS mutant inhibits the interaction between RAS and RAF

Biochemical and Biophysical Research Communications
2023-02 | Journal article
Contributors: Youn Hee Jung; Yoonjoo Choi; Hyo-Deok Seo; Moon-Hyeong Seo; Hak-Sung Kim
Source: check_circle
Crossref

Fever temperatures modulate intraprotein dynamics and enhance the binding affinity between monoclonal antibodies and the Spike protein from SARS-CoV-2

2022-10-25 | Preprint
Contributors: Dong Gun Kim; Hak Sung Kim; Yoonjoo Choi; Razvan C. Stan
Source: check_circle
Crossref

Computationally-guided design and affinity improvement of a protein binder targeting a specific site on HER2

Computational and Structural Biotechnology Journal
2021 | Journal article
Part of ISSN: 2001-0370
Source: Self-asserted source
Yoonjoo Choi
grade
Preferred source (of 2)‎

Deimmunization of flagellin for repeated administration as a vaccine adjuvant

npj Vaccines
2021-09-13 | Journal article
Contributors: Koemchhoy Khim; Yong Jun Bang; Sao Puth; Yoonjoo Choi; Youn Suhk Lee; Kwangjoon Jeong; Shee Eun Lee; Joon Haeng Rhee
Source: check_circle
Crossref

Wet Lab Goes Virtual: In Silico Tools, ELN s, and Big Data Help Scientists Generate and Analyze Wet‐lab Data

Digital Transformation of the Laboratory
2021-08-16 | Other
Source: Self-asserted source
Yoonjoo Choi

Epitope–Paratope Interaction of a Neutralizing Human Anti-Hepatitis B Virus PreS1 Antibody That Recognizes the Receptor-Binding Motif

Vaccines
2021-07-07 | Journal article
Contributors: Jisu Hong; Youngjin Choi; Yoonjoo Choi; Jiwoo Lee; Hyo Jeong Hong
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Epitopes of Protein Binders Are Related to the Structural Flexibility of a Target Protein Surface

Journal of Chemical Information and Modeling
2021-04-26 | Journal article
Contributors: Dong-Gun Kim; Yoonjoo Choi; Hak-Sung Kim
Source: check_circle
Crossref

The Ethical Problems of CRISPR-Cas9 Gene-editing Technology

The Journal of Humanities
2020-11-30 | Journal article
Part of ISSN: 2508-4550
Source: Self-asserted source
Yoonjoo Choi

Generation and Characterization of Monoclonal Antibodies to the Ogawa Lipopolysaccharide of Vibrio cholerae O1 from Phage-Displayed Human Synthetic Fab Library

Journal of Microbiology and Biotechnology
2020-11-28 | Journal article
Part of ISSN: 1017-7825
Part of ISSN: 1738-8872
Source: Self-asserted source
Yoonjoo Choi

A Chimeric Antigen Receptor That Binds to a Conserved Site on MICA

ImmunoHorizons
2020-10-01 | Journal article
Contributors: W James Cook; Yoonjoo Choi; Albert Gacerez; Chris Bailey-Kellogg; Charles L Sentman
Source: check_circle
Crossref

A regulatory SH2 domain-targeting protein binder effectively inhibits the activity of Bruton’s tyrosine kinase and its drug-resistant variants

Biochemical and Biophysical Research Communications
2020-05 | Journal article
Contributors: Sukyo Jeong; Yoo-Kyoung Sohn; Yoonjoo Choi; Jinho Park; Hak-Sung Kim
Source: check_circle
Crossref

Effective inhibition of C3a‐mediated pro‐inflammatory response by a human C3a‐specific protein binder

Biotechnology and Bioengineering
2020-03-04 | Journal article
Part of ISSN: 0006-3592
Part of ISSN: 1097-0290
Source: Self-asserted source
Yoonjoo Choi

Computer-guided Binding Mode Identification and Affinity Improvement of an LRR Protein Binder without Structure Determination

2019-12-19 | Other
Contributors: Yoonjoo Choi; Sukyo Jeong; Jung-Min Choi; Christian Ndong; Chris Bailey-Kellogg; Karl E. Griswold; Hak-Sung Kim
Source: Self-asserted source
Yoonjoo Choi
grade
Preferred source (of 3)‎

B-SIDER: Computational Algorithm for the Design of Complementary β-Sheet Sequences

Journal of Chemical Information and Modeling
2019-10-28 | Journal article
Contributors: Tae-Geun Yu; Hak-Sung Kim; Yoonjoo Choi
Source: Self-asserted source
Yoonjoo Choi
grade
Preferred source (of 3)‎

Repeat Module-Based Rational Design of a Photoswitchable Protein for Light-Driven Control of Biological Processes

Angewandte Chemie International Edition
2018-08-20 | Journal article
Contributors: Woosung Heu; Jung Min Choi; Hyun-Ho Kyeong; Yoonjoo Choi; Hee Yeon Kim; Hak-Sung Kim
Source: Self-asserted source
Yoonjoo Choi
grade
Preferred source (of 3)‎

DisruPPI: structure-based computational redesign algorithm for protein binding disruption

Bioinformatics
2018-06 | Journal article
Part of ISSN: 1367-4803
Contributors: Yoonjoo Choi; Jacob M Furlon; Ryan B Amos; Karl E Griswold; Chris Bailey-Kellogg
Source: Self-asserted source
Yoonjoo Choi via Crossref Metadata Search

Computationally-driven identification of antibody epitopes

eLife
2017 | Journal article
Part of ISSN: 2050-084X
Contributors: Casey K Hua; Albert T Gacerez; Charles L Sentman; Margaret E Ackerman; Yoonjoo Choi; Chris Bailey-Kellogg
Source: Self-asserted source
Yoonjoo Choi via Crossref Metadata Search
grade
Preferred source (of 2)‎

GradDock: rapid simulation and tailored ranking functions for peptide-MHC Class I docking

Bioinformatics
2017-09 | Journal article
Part of ISSN: 1367-4803
Contributors: Hyun-Ho Kyeong; Yoonjoo Choi; Hak-Sung Kim; Alfonso Valencia
Source: Self-asserted source
Yoonjoo Choi via Crossref Metadata Search

EpiSweep: Computationally Driven Reengineering of Therapeutic Proteins to Reduce Immunogenicity While Maintaining Function

Computational Protein Design
2016 | Other
Part of ISBN: 9781493966356
Part of ISSN: 1064-3745
Contributors: Yoonjoo Choi; Deeptak Verma; Karl E. Griswold; Chris Bailey-Kellogg
Source: Self-asserted source
Yoonjoo Choi via Crossref Metadata Search

Computationally driven antibody engineering enables simultaneous humanization and thermostabilization

Protein Engineering Design and Selection
2016-06 | Journal article
Part of ISSN: 1741-0126
Contributors: Yoonjoo Choi; Christian Ndong; Karl E. Griswold; Chris Bailey-Kellogg
Source: Self-asserted source
Yoonjoo Choi via Crossref Metadata Search

Structure-based redesign of lysostaphin yields potent antistaphylococcal enzymes that evade immune cell surveillance

Molecular Therapy - Methods & Clinical Development
2015 | Journal article
Part of ISSN: 2329-0501
Contributors: Kristina Blazanovic; Hongliang Zhao; Yoonjoo Choi; Wen Li; Regina S Salvat; Daniel C Osipovitch; Jennifer Fields; Leonard Moise; Brent L Berwin; Steven N Fiering et al.
Source: Self-asserted source
Yoonjoo Choi via Crossref Metadata Search

Antibody humanization by structure-based computational protein design

mAbs
2015-08-07 | Journal article
Part of ISSN: 1942-0862
Contributors: Yoonjoo Choi; Casey Hua; Charles L Sentman; Margaret E Ackerman; Chris Bailey-Kellogg
Source: Self-asserted source
Yoonjoo Choi via Crossref Metadata Search

Depletion of T Cell Epitopes in Lysostaphin Mitigates Anti-Drug Antibody Response and Enhances Antibacterial Efficacy In Vivo

Chemistry & Biology
2015-05 | Journal article
Part of ISSN: 1074-5521
Contributors: Hongliang Zhao; Deeptak Verma; Wen Li; Yoonjoo Choi; Christian Ndong; Steven N. Fiering; Chris Bailey-Kellogg; Karl E. Griswold
Source: Self-asserted source
Yoonjoo Choi via Crossref Metadata Search

Protein deimmunization via structure-based design enables efficient epitope deletion at high mutational loads

Biotechnology and Bioengineering
2015-02 | Journal article
Part of ISSN: 0006-3592
Contributors: Regina S. Salvat; Yoonjoo Choi; Alexandra Bishop; Chris Bailey-Kellogg; Karl E. Griswold
Source: Self-asserted source
Yoonjoo Choi via Crossref Metadata Search

Mapping the Pareto Optimal Design Space for a Functionally Deimmunized Biotherapeutic Candidate

PLoS Computational Biology
2015-01-08 | Journal article
Part of ISSN: 1553-7358
Contributors: Regina S. Salvat; Andrew S. Parker; Yoonjoo Choi; Chris Bailey-Kellogg; Karl E. Griswold; Becca Asquith
Source: Self-asserted source
Yoonjoo Choi via Crossref Metadata Search

Protein Modeling and Structural Prediction

Springer Handbook of Bio-/Neuroinformatics
2014 | Other
Part of ISBN: 9783642305733
Contributors: Sebastian Kelm; Yoonjoo Choi; Charlotte M. Deane
Source: Self-asserted source
Yoonjoo Choi via Crossref Metadata Search

Computationally driven deletion of broadly distributed T cell epitopes in a biotherapeutic candidate

Cellular and Molecular Life Sciences
2014-06-01 | Journal article
Part of ISSN: 1420-682X
Contributors: Regina S. Salvat; Andrew S. Parker; Andrew Guilliams; Yoonjoo Choi; Chris Bailey-Kellogg; Karl E. Griswold
Source: Self-asserted source
Yoonjoo Choi via Crossref Metadata Search

Gene and Protein Sequence Optimization for High-Level Production of Fully Active and Aglycosylated Lysostaphin in Pichia pastoris

Applied and Environmental Microbiology
2014-02 | Journal article
Part of ISSN: 0099-2240
Contributors: H. Zhao; K. Blazanovic; Y. Choi; C. Bailey-Kellogg; K. E. Griswold
Source: Self-asserted source
Yoonjoo Choi via Crossref Metadata Search

Fragment-based modeling of membrane protein loops: Successes, failures, and prospects for the future

Proteins: Structure, Function, and Bioinformatics
2013-10 | Journal article
Part of ISSN: 0887-3585
Contributors: Sebastian Kelm; Anna Vangone; Yoonjoo Choi; Jean-Paul Ebejer; Jiye Shi; Charlotte M. Deane
Source: Self-asserted source
Yoonjoo Choi via Crossref Metadata Search

How long is a piece of loop?

PeerJ
2013-02 | Journal article
Part of ISSN: 2167-8359
Contributors: Yoonjoo Choi; Sumeet Agarwal; Charlotte M. Deane
Source: Self-asserted source
Yoonjoo Choi via Crossref Metadata Search

Structure-Guided Deimmunization of Therapeutic Proteins

Journal of Computational Biology
2013-02 | Journal article
Part of ISSN: 1066-5277
Contributors: Andrew S. Parker; Yoonjoo Choi; Karl E. Griswold; Chris Bailey-Kellogg
Source: Self-asserted source
Yoonjoo Choi via Crossref Metadata Search

Structure-based redesign of proteins for minimal T-cell epitope content

Journal of Computational Chemistry
2013-01-08 | Journal article
Part of ISSN: 0192-8651
Contributors: Yoonjoo Choi; Karl E. Griswold; Chris Bailey-Kellogg
Source: Self-asserted source
Yoonjoo Choi via Crossref Metadata Search

Predicting antibody complementarity determining region structures without classification

Molecular BioSystems
2011 | Journal article
Part of ISSN: 1742-206X
Contributors: Yoonjoo Choi; Charlotte M. Deane
Source: Self-asserted source
Yoonjoo Choi via Crossref Metadata Search

Developing Stochastic Models for Spatial Inference: Bacterial Chemotaxis

PLoS ONE
2010-05 | Journal article
Part of ISSN: 1932-6203
Contributors: Yoon-Dong Yu; Yoonjoo Choi; Yik-Ying Teo; Andrew R. Dalby; Eshel Ben-Jacob
Source: Self-asserted source
Yoonjoo Choi via Crossref Metadata Search

FREAD revisited: Accurate loop structure prediction using a database search algorithm

Proteins: Structure, Function, and Bioinformatics
2009 | Journal article
Part of ISSN: 0887-3585
Contributors: Yoonjoo Choi; Charlotte M. Deane
Source: Self-asserted source
Yoonjoo Choi via Crossref Metadata Search

Peer review (2 reviews for 2 publications/grants)

Review activity for PLoS computational biology. (1)
Review activity for Theoretical biology and medical modelling (1)