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Works (37)

A Four-Gene Signature from Blood to Exclude Bacterial Etiology of Lower Respiratory Tract Infection in Adults

2025-02-27 | Preprint
Contributors: Ann Falsey; Derick Peterson; Edward Walsh; Andrea Baran; Chin-Yi Chu; Angela Branche; Daniel Croft; Micheal Peasley; Anthony Corbett; John Ashton et al.
Source: check_circle
Crossref

Scaffold-mediated CRISPR-Cas9 delivery system for acute myeloid leukemia therapy

Science Advances
2021-05-21 | Journal article
Contributors: Tzu-Chieh Ho; Hye Sung Kim; Yumei Chen; Yamin Li; Mark W. LaMere; Caroline Chen; Hui Wang; Jing Gong; Cal D. Palumbo; John M. Ashton et al.
Source: check_circle
Crossref

Pro-inflammatory cytokine blockade attenuates myeloid expansion in a murine model of rheumatoid arthritis.

Haematologica
2019-05-17 | Journal article
Source: Self-asserted source
John Ashton

Aged marrow macrophages expand platelet-biased hematopoietic stem cells via Interleukin1B.

JCI insight
2019-04-18 | Journal article
Source: Self-asserted source
John Ashton
grade
Preferred source (of 2)‎

Decellularized Wharton jelly matrix: a biomimetic scaffold for ex vivo hematopoietic stem cell culture.

Blood advances
2019-04-01 | Journal article
Source: Self-asserted source
John Ashton

The Hematopoietic Oxidase NOX2 Regulates Self-Renewal of Leukemic Stem Cells.

Cell reports
2019-04-01 | Journal article
Source: Self-asserted source
John Ashton

A novel in vitro model of primary human pediatric lung epithelial cells.

Pediatric research
2019-02-18 | Journal article
Source: Self-asserted source
John Ashton

Subversion of Systemic Glucose Metabolism as a Mechanism to Support the Growth of Leukemia Cells.

Cancer cell
2018-09-27 | Journal article
Source: Self-asserted source
John Ashton

ARID1A, a SWI/SNF subunit, is critical to acinar cell homeostasis and regeneration and is a barrier to transformation and epithelial-mesenchymal transition in the pancreas.

Gut
2018-09-18 | Journal article
Source: Self-asserted source
John Ashton

Dissociation, cellular isolation, and initial molecular characterization of neonatal and pediatric human lung tissues.

American journal of physiology. Lung cellular and molecular physiology
2018-07-05 | Journal article
Source: Self-asserted source
John Ashton

AMPK/FIS1-Mediated Mitophagy Is Required for Self-Renewal of Human AML Stem Cells.

Cell stem cell
2018-06-14 | Journal article
Source: Self-asserted source
John Ashton

Targeting the gut microbiome to treat the osteoarthritis of obesity.

JCI insight
2018-04-19 | Journal article
Source: Self-asserted source
John Ashton

T cell developmental arrest in former premature infants increases risk of respiratory morbidity later in infancy.

JCI insight
2018-02-22 | Journal article
Source: Self-asserted source
John Ashton

Developmental alcohol exposure impairs synaptic plasticity without overtly altering microglial function in mouse visual cortex.

Brain, behavior, and immunity
2017-09-14 | Journal article
Source: Self-asserted source
John Ashton

Transcriptomic Biomarkers to Discriminate Bacterial from Nonbacterial Infection in Adults Hospitalized with Respiratory Illness.

Scientific reports
2017-07-26 | Journal article
Source: Self-asserted source
John Ashton

DNA methyltransferase 3b regulates articular cartilage homeostasis by altering metabolism.

JCI insight
2017-06-15 | Journal article
Source: Self-asserted source
John Ashton

HIV-1 Frameshift RNA-Targeted Triazoles Inhibit Propagation of Replication-Competent and Multi-Drug-Resistant HIV in Human Cells.

ACS chemical biology
2017-05-05 | Journal article
Source: Self-asserted source
John Ashton

Tudor-SN-mediated endonucleolytic decay of human cell microRNAs promotes G1/S phase transition.

Science (New York, N.Y.)
2017-05-01 | Journal article
Source: Self-asserted source
John Ashton
grade
Preferred source (of 2)‎

Index case of acute myeloid leukemia in a family harboring a novel CEBPA germ line mutation.

Blood advances
2017-03-14 | Journal article
Source: Self-asserted source
John Ashton
grade
Preferred source (of 2)‎

Targeted therapy for a subset of acute myeloid leukemias that lack expression of aldehyde dehydrogenase 1A1.

Haematologica
2017-03-09 | Journal article
Source: Self-asserted source
John Ashton

Rational design of a parthenolide-based drug regimen that selectively eradicates acute myelogenous leukemia stem cells.

The Journal of biological chemistry
2016-11-01 | Journal article
Source: Self-asserted source
John Ashton

Rational Design of a Parthenolide-based Drug Regimen That Selectively Eradicates Acute Myelogenous Leukemia Stem Cells.

The Journal of biological chemistry
2016-08-29 | Journal article
Source: Self-asserted source
John Ashton

Evolution of acute myelogenous leukemia stem cell properties after treatment and progression.

Blood
2016-07-15 | Journal article
Source: Self-asserted source
John Ashton
grade
Preferred source (of 2)‎

Leukemic Stem Cells Evade Chemotherapy by Metabolic Adaptation to an Adipose Tissue Niche.

Cell stem cell
2016-06-30 | Journal article
Source: Self-asserted source
John Ashton

miRge - A Multiplexed Method of Processing Small RNA-Seq Data to Determine MicroRNA Entropy.

PloS one
2015-11-16 | Journal article
Source: Self-asserted source
John Ashton

Residual Disease in a Novel Xenograft Model of RUNX1-Mutated, Cytogenetically Normal Acute Myeloid Leukemia.

PloS one
2015-07-15 | Journal article
Source: Self-asserted source
John Ashton

Targeting aberrant glutathione metabolism to eradicate human acute myelogenous leukemia cells.

The Journal of biological chemistry
2013-10-02 | Journal article
Source: Self-asserted source
John Ashton

In Vivo RNAi screening identifies a leukemia-specific dependence on integrin beta 3 signaling.

Cancer cell
2013-06-13 | Journal article
Source: Self-asserted source
John Ashton

BCL-2 inhibition targets oxidative phosphorylation and selectively eradicates quiescent human leukemia stem cells.

Cell stem cell
2013-01-17 | Journal article
Source: Self-asserted source
John Ashton

p75NTR: an enhancer of fenretinide toxicity in neuroblastoma.

Cancer chemotherapy and pharmacology
2013-01-13 | Journal article
Source: Self-asserted source
John Ashton

Gene sets identified with oncogene cooperativity analysis regulate in vivo growth and survival of leukemia stem cells.

Cell stem cell
2012-08-02 | Journal article
Source: Self-asserted source
John Ashton

Noncanonical NF-κB signaling regulates hematopoietic stem cell self-renewal and microenvironment interactions.

Stem cells (Dayton, Ohio)
2012-04-01 | Journal article
Source: Self-asserted source
John Ashton

Functional inhibition of osteoblastic cells in an in vivo mouse model of myeloid leukemia.

Blood
2011-09-28 | Journal article
Source: Self-asserted source
John Ashton

Metabolic regulation of APOBEC-1 complementation factor trafficking in mouse models of obesity and its positive correlation with the expression of ApoB protein in hepatocytes.

Biochimica et biophysica acta
2010-06-09 | Journal article
Source: Self-asserted source
John Ashton

Leukemia stem cells in a genetically defined murine model of blast-crisis CML.

Blood
2007-06-29 | Journal article
Source: Self-asserted source
John Ashton

Proteomic profiling and identification of immunodominant spore antigens of Bacillus anthracis, Bacillus cereus, and Bacillus thuringiensis.

Applied and environmental microbiology
2006-09-01 | Journal article
Source: Self-asserted source
John Ashton

A rapid and sensitive magnetic bead-based immunoassay for the detection of staphylococcal enterotoxin B for high-through put screening.

Molecular and cellular probes
2004-12-01 | Journal article
Source: Self-asserted source
John Ashton

Peer review (6 reviews for 2 publications/grants)

Review activity for BMC genomics (5)
Review activity for Nature communications (1)