Personal information

Emails & domains

Verified email domains

Websites & social links

Tohoku University
researchmap

Keywords

cryo-electron microscopy, translation, transcription, antibiotics, synthetic biology

Countries

Japan

Activities

Collapse all

Education and qualifications (3)

The University of Tokyo: Tokyo, JP

2005-04 to 2008-05 | PhD (Department of Chemistry and Biotechnology, School of Engineering)
Education
Source: Self-asserted source
takeshi yokoyama

The University of Tokyo: Tokyo, JP

2003-04 to 2005-03 | Msc (Department of Integrated Biosciences, Graduate School of Frontier Sciences)
Education
Source: Self-asserted source
takeshi yokoyama

Meiji University: Kanagawa, JP

1999-04 to 2003-03 | Bsc (School of Agriculture)
Education
Source: Self-asserted source
takeshi yokoyama

Works (29)

Structural insight into bacterial co-transcriptional translation initiation

2024-03-21 | Preprint
DOI: 10.1101/2024.03.19.585385
Contributors: Takeshi Yokoyama; Yuko Murayama; Tomomi Uchikubo-Kamo; Yuri Tomabechi; Asuteka Nagao; Tsutomu Suzuki; Mikako Shirouzu; Shun-ichi Sekine
Source: Self-asserted source
takeshi yokoyama

Boric acid intercepts 80S ribosome migration from AUG-stop by stabilizing eRF1

Nature Chemical Biology
2024-01-24 | Journal article | Author
DOI: 10.1038/s41589-023-01513-0
Part of ISSN: 1552-4450
Part of ISSN: 1552-4469
Contributors: Mayuki Tanaka; takeshi yokoyama; Hironori Saito; Madoka Nishimoto; Kengo Tsuda; Naoyuki Sotta; Hideki Shigematsu; Mikako Shirouzu; Shintaro Iwasaki; Takuhiro Ito et al.
Source: Self-asserted source
takeshi yokoyama

Direct visualization of ribosomes in the cell-free system revealed the functional evolution of aminoglycoside

The Journal of Biochemistry
2024-01-16 | Journal article | Author
DOI: 10.1093/jb/mvae002
Part of ISSN: 0021-924X
Part of ISSN: 1756-2651
Contributors: Junta Tomono; Kosuke Asano; Takuma Chiashi; Masato Suzuki; Masayuki Igarashi; Yoshiaki Takahashi; Yoshikazu Tanaka; takeshi yokoyama
Source: Self-asserted source
takeshi yokoyama

Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth

Cell
2023-12 | Journal article
DOI: 10.1016/j.cell.2023.10.026
Part of ISSN: 0092-8674
Contributors: Xuewei Zhao; Ding Ma; Kensuke Ishiguro; Hironori Saito; Shinichiro Akichika; Ikuya Matsuzawa; Mari Mito; Toru Irie; Kota Ishibashi; Kimi Wakabayashi et al.
Source: Self-asserted source
takeshi yokoyama

Synthesis of epitope‐targeting nanobody based on native protein–protein interactions for FtsZ filamentation suppressor

Biotechnology Journal
2023-11 | Journal article
DOI: 10.1002/biot.202300039
Part of ISSN: 1860-6768
Part of ISSN: 1860-7314
Contributors: Hikaru Nakazawa; Taiji Katsuki; Takashi Matsui; Atsushi Tsugita; Takeshi Yokoyama; Tomoyuki Ito; Sakiya Kawada; Yoshikazu Tanaka; Mitsuo Umetsu
Source: Self-asserted source
takeshi yokoyama

Simple Method for the Creation of a Bacteria-Sized Unilamellar Liposome with Different Proteins Localized to the Respective Sides of the Membrane

ACS Synthetic Biology
2023-05-19 | Journal article
DOI: 10.1021/acssynbio.2c00564
Part of ISSN: 2161-5063
Part of ISSN: 2161-5063
Contributors: Kosaku Noba; Shogo Yoshimoto; Yoshikazu Tanaka; Takeshi Yokoyama; Tomoaki Matsuura; Katsutoshi Hori
Source: Self-asserted source
takeshi yokoyama

RPL3L-containing ribosomes determine translation elongation dynamics required for cardiac function

Nature Communications
2023-04-20 | Journal article | Author
DOI: 10.1038/s41467-023-37838-6
Part of ISSN: 2041-1723
Contributors: Chisa Shiraishi; Akinobu Matsumoto; Kazuya Ichihara; Taishi Yamamoto; takeshi yokoyama; Taisuke Mizoo; Atsushi Hatano; Masaki Matsumoto; Yoshikazu Tanaka; Eriko Matsuura-Suzuki et al.
Source: Self-asserted source
takeshi yokoyama

Structural basis of the transcription termination factor Rho engagement with transcribing RNA polymerase from Thermus thermophilus

Science Advances
2023-02-10 | Journal article | Author
DOI: 10.1126/sciadv.ade7093
Part of ISSN: 2375-2548
Contributors: Yuko Murayama; Haruhiko Ehara; Mari Aoki; Mie Goto; takeshi yokoyama; Shun-ichi Sekine
Source: Self-asserted source
takeshi yokoyama

A marine sponge-derived lectin reveals hidden pathway for thrombopoietin receptor activation

Nature Communications
2022-11-25 | Journal article
DOI: 10.1038/s41467-022-34921-2
Part of ISSN: 2041-1723
Contributors: Hiromi Watari; Hiromu Kageyama; Nami Masubuchi; Hiroya Nakajima; Kako Onodera; Pamela Focia; Takumi Oshiro; Takashi Matsui; Yoshio Kodera; Tomohisa Ogawa et al.
Source: Self-asserted source
takeshi yokoyama

The carbohydrate tail of landomycin A is responsible for its interaction with the repressor protein LanK

The FEBS Journal
2022-10 | Journal article
DOI: 10.1111/febs.16460
Part of ISSN: 1742-464X
Part of ISSN: 1742-4658
Contributors: Atsushi Tsugita; Shiro Uehara; Takashi Matsui; Takeshi Yokoyama; Iryna Ostash; Maksym Deneka; Subbarao Yalamanchili; Clay S. Bennett; Yoshikazu Tanaka; Bohdan Ostash
Source: Self-asserted source
takeshi yokoyama

Chimeric mutants of staphylococcal hemolysin, which act as both one‐component and two‐component hemolysin, created by grafting the stem domain

The FEBS Journal
2022-06 | Journal article
DOI: 10.1111/febs.16354
Part of ISSN: 1742-464X
Part of ISSN: 1742-4658
Contributors: Nouran Ghanem; Natsuki Kanagami; Takashi Matsui; Kein Takeda; Jun Kaneko; Yasuyuki Shiraishi; Christian A. Choe; Tomomi Uchikubo‐Kamo; Mikako Shirouzu; Tsubasa Hashimoto et al.
Source: Self-asserted source
takeshi yokoyama

Amyloid conformation-dependent disaggregation in a reconstituted yeast prion system

Nature Chemical Biology
2022-03 | Journal article
DOI: 10.1038/s41589-021-00951-y
Part of ISSN: 1552-4450
Part of ISSN: 1552-4469
Contributors: Yoshiko Nakagawa; Howard C.-H. Shen; Yusuke Komi; Shinju Sugiyama; Takaaki Kurinomaru; Yuri Tomabechi; Elena Krayukhina; Kenji Okamoto; Takeshi Yokoyama; Mikako Shirouzu et al.
Source: Self-asserted source
takeshi yokoyama

The landscape of translational stall sites in bacteria revealed by monosome and disome profiling

RNA
2022-03 | Journal article
DOI: 10.1261/rna.078188.120
Part of ISSN: 1355-8382
Part of ISSN: 1469-9001
Contributors: Tomoya Fujita; Takeshi Yokoyama; Mikako Shirouzu; Hideki Taguchi; Takuhiro Ito; Shintaro Iwasaki
Source: Self-asserted source
takeshi yokoyama

Cryo-EM structure of the human ELMO1-DOCK5-Rac1 complex

Science Advances
2021-07-23 | Journal article | Author
DOI: 10.1126/sciadv.abg3147
Part of ISSN: 2375-2548
Contributors: Mutsuko Kukimoto-Niino; Kazushige Katsura; Rahul Kaushik; Haruhiko Ehara; takeshi yokoyama; Tomomi Uchikubo-Kamo; Reiko Nakagawa; Chiemi Mishima-Tsumagari; Mayumi Yonemochi; Mariko Ikeda et al.
Source: Self-asserted source
takeshi yokoyama

Anti-EGFR antibody 528 binds to domain III of EGFR at a site shifted from the cetuximab epitope

Scientific Reports
2021-03-11 | Journal article
DOI: 10.1038/s41598-021-84171-3
Part of ISSN: 2045-2322
Contributors: Koki Makabe; Takeshi Yokoyama; Shiro Uehara; Tomomi Uchikubo-Kamo; Mikako Shirouzu; Kouki Kimura; Kouhei Tsumoto; Ryutaro Asano; Yoshikazu Tanaka; Izumi Kumagai
Source: Self-asserted source
takeshi yokoyama

Cryo-EM structure of the volume-regulated anion channel LRRC8D isoform identifies features important for substrate permeation

Communications Biology
2020-05-15 | Journal article
DOI: 10.1038/s42003-020-0951-z
Part of ISSN: 2399-3642
Contributors: Ryoki Nakamura; Tomohiro Numata; Go Kasuya; Takeshi Yokoyama; Tomohiro Nishizawa; Tsukasa Kusakizako; Takafumi Kato; Tatsuya Hagino; Naoshi Dohmae; Masato Inoue et al.
Source: Self-asserted source
takeshi yokoyama

Structural insights into tetraspanin CD9 function

Nature Communications
2020-03-30 | Journal article
DOI: 10.1038/s41467-020-15459-7
Part of ISSN: 2041-1723
Contributors: Rie Umeda; Yuhkoh Satouh; Mizuki Takemoto; Yoshiko Nakada-Nakura; Kehong Liu; Takeshi Yokoyama; Mikako Shirouzu; So Iwata; Norimichi Nomura; Ken Sato et al.
Source: Self-asserted source
takeshi yokoyama

Cryo-EM structure of the human L-type amino acid transporter 1 in complex with glycoprotein CD98hc

Nature Structural & Molecular Biology
2019-06 | Journal article
DOI: 10.1038/s41594-019-0237-7
Part of ISSN: 1545-9993
Part of ISSN: 1545-9985
Contributors: Yongchan Lee; Pattama Wiriyasermkul; Chunhuan Jin; Lili Quan; Ryuichi Ohgaki; Suguru Okuda; Tsukasa Kusakizako; Tomohiro Nishizawa; Kazumasa Oda; Ryuichiro Ishitani et al.
Source: Self-asserted source
takeshi yokoyama

HCV IRES Captures an Actively Translating 80S Ribosome

Molecular Cell
2019-06 | Journal article
DOI: 10.1016/j.molcel.2019.04.022
Part of ISSN: 1097-2765
Contributors: Takeshi Yokoyama; Kodai Machida; Wakana Iwasaki; Tomoaki Shigeta; Madoka Nishimoto; Mari Takahashi; Ayako Sakamoto; Mayumi Yonemochi; Yoshie Harada; Hideki Shigematsu et al.
Source: Self-asserted source
takeshi yokoyama

Structural basis for eIF2B inhibition in integrated stress response

Science
2019-05-03 | Journal article | Author
DOI: 10.1126/science.aaw4104
Part of ISSN: 0036-8075
Part of ISSN: 1095-9203
Contributors: Kazuhiro Kashiwagi; takeshi yokoyama; Madoka Nishimoto; Mari Takahashi; Ayako Sakamoto; Mayumi Yonemochi; Mikako Shirouzu; Takuhiro Ito
Source: Self-asserted source
takeshi yokoyama

Cryo-EM structures of the human volume-regulated anion channel LRRC8

Nature Structural & Molecular Biology
2018-09 | Journal article
DOI: 10.1038/s41594-018-0109-6
Part of ISSN: 1545-9993
Part of ISSN: 1545-9985
Contributors: Go Kasuya; Takanori Nakane; Takeshi Yokoyama; Yanyan Jia; Masato Inoue; Kengo Watanabe; Ryoki Nakamura; Tomohiro Nishizawa; Tsukasa Kusakizako; Akihisa Tsutsumi et al.
Source: Self-asserted source
takeshi yokoyama

Dynamic functional assembly of the Torsin AAA+ ATPase and its modulation by LAP1

Molecular Biology of the Cell
2017-10-15 | Journal article
DOI: 10.1091/mbc.e17-05-0281
Part of ISSN: 1059-1524
Part of ISSN: 1939-4586
Contributors: Anna R. Chase; Ethan Laudermilch; Jimin Wang; Hideki Shigematsu; Takeshi Yokoyama; Christian Schlieker
Source: Self-asserted source
takeshi yokoyama

Structure of the complete elongation complex of RNA polymerase II with basal factors

Science
2017-09 | Journal article | Author
DOI: 10.1126/science.aan8552
Part of ISSN: 0036-8075
Part of ISSN: 1095-9203
Contributors: Haruhiko Ehara; takeshi yokoyama; Hideki Shigematsu; Shigeyuki Yokoyama; Mikako Shirouzu; Shun-ichi Sekine
Source: Self-asserted source
takeshi yokoyama

Chemical and structural characterization of a model Post-Termination Complex (PoTC) for the ribosome recycling reaction: Evidence for the release of the mRNA by RRF and EF-G

PLOS ONE
2017-05-24 | Journal article
DOI: 10.1371/journal.pone.0177972
Part of ISSN: 1932-6203
Contributors: Nobuhiro Iwakura; Takeshi Yokoyama; Fabio Quaglia; Kaoru Mitsuoka; Kazuhiro Mio; Hideki Shigematsu; Mikako Shirouzu; Akira Kaji; Hideko Kaji
Source: Self-asserted source
takeshi yokoyama

Structural Basis of Backwards Motion in Kinesin-1-Kinesin-14 Chimera: Implication for Kinesin-14 Motility

Structure
2016-08 | Journal article
DOI: 10.1016/j.str.2016.05.021
Part of ISSN: 0969-2126
Contributors: Masahiko Yamagishi; Hideki Shigematsu; Takeshi Yokoyama; Masahide Kikkawa; Mitsuhiro Sugawa; Mari Aoki; Mikako Shirouzu; Junichiro Yajima; Ryo Nitta
Source: Self-asserted source
takeshi yokoyama

Pseudoatomic Structure of the Tripartite Multidrug Efflux Pump AcrAB-TolC Reveals the Intermeshing Cogwheel-like Interaction between AcrA and TolC

Structure
2016-02 | Journal article
DOI: 10.1016/j.str.2015.12.007
Part of ISSN: 0969-2126
Contributors: Hyeongseop Jeong; Jin-Sik Kim; Saemee Song; Hideki Shigematsu; Takeshi Yokoyama; Jaekyung Hyun; Nam-Chul Ha
Source: Self-asserted source
takeshi yokoyama

Structural insights into initial and intermediate steps of the ribosome-recycling process

The EMBO Journal
2012-04-04 | Journal article
DOI: 10.1038/emboj.2012.22
Part of ISSN: 0261-4189
Contributors: Takeshi Yokoyama; Tanvir R Shaikh; Nobuhiro Iwakura; Hideko Kaji; Akira Kaji; Rajendra K Agrawal
Source: Self-asserted source
takeshi yokoyama

Ribosomal RNAs are tolerant toward genetic insertions: evolutionary origin of the expansion segments

Nucleic Acids Research
2008-06 | Journal article
DOI: 10.1093/nar/gkn224
Part of ISSN: 1362-4962
Part of ISSN: 0305-1048
Contributors: Takeshi Yokoyama; Tsutomu Suzuki
Source: Self-asserted source
takeshi yokoyama

Ligand-induced translation by the allosteric ribosome bearing an aptamer-fused rRNA

Nucleic Acids Symposium Series
2007-11-01 | Journal article
DOI: 10.1093/nass/nrm192
Part of ISSN: 0261-3166
Part of ISSN: 1746-8272
Contributors: T. Yokoyama; T. Suzuki
Source: Self-asserted source
takeshi yokoyama
How many people are using ORCID?