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Employment (1)

Chongqing Medical University: Chongqing, CN

Employment
Source: Self-asserted source
Xuemei Zhang

Education and qualifications (2)

Chongqing Medical University: Chongqing, CN

Education
Source: Self-asserted source
Xuemei Zhang

Chongqing Medical University: Chongqing, CN

Qualification
Source: Self-asserted source
Xuemei Zhang

Works (50 of 76)

Items per page:
Page 1 of 2

Detoxified pneumolysin derivative ΔA146Ply inhibits triple- negative breast cancer metastasis mainly via mannose receptor-mediated autophagy inhibition

Virulence
2024-12-31 | Journal article
DOI: 10.1080/21505594.2023.2283898
Contributors: Hong Zhang; Tao Zhu; Wenchun Xu; Bichen Liu; Kaifeng Wu; Yibing Yin; Xuemei Zhang
Source: check_circle
Crossref

ΔA146Ply-HA stem protein immunization protects mice against influenza A virus infection and co-infection with Streptococcus pneumoniae

Molecular Immunology
2023-09 | Journal article
DOI: 10.1016/j.molimm.2023.07.011
Contributors: Lian Li; Ting Guo; Yuan Yuan; Jiangming Xiao; Rui Yang; Hanyi Wang; Wenlong Xu; Yibing Yin; Xuemei Zhang
Source: check_circle
Crossref

comCDE (Competence) Operon Is Regulated by CcpA in Streptococcus pneumoniae D39

Microbiology Spectrum
2023-06-15 | Journal article
DOI: 10.1128/spectrum.00012-23
Contributors: Yapeng Zhang; Jinghui Zhang; Jiangming Xiao; Hanyi Wang; Rui Yang; Xinlin Guo; Yuqiang Zheng; Yibing Yin; Xuemei Zhang; Hui Wang
Source: check_circle
Crossref

rM2e-ΔPly protein immunization induces protection against influenza viruses and its co-infection with Streptococcus pneumoniae in mice

Molecular Immunology
2022-12 | Journal article
DOI: 10.1016/j.molimm.2022.10.006
Contributors: Ting Guo; Jiangming Xiao; Lian Li; Wenlong Xu; Yuan Yuan; Yibing Yin; Xuemei Zhang
Source: check_circle
Crossref

CD5L attenuates allergic airway inflammation by expanding CD11chigh alveolar macrophages and inhibiting NLRP3 inflammasome activation via HDAC2

Immunology
2022-11 | Journal article
DOI: 10.1111/imm.13543
Contributors: Danlin Weng; Song Gao; Hailan Shen; Shifei Yao; Qi Huang; Yanyu Zhang; Wenjie Huang; Yan Wang; Xuemei Zhang; Yibing Yin et al.
Source: check_circle
Crossref

Detoxified pneumolysin derivative ΔA146Ply inhibits autophagy and induces apoptosis in acute myeloid leukemia cells by activating mTOR signaling

Experimental & Molecular Medicine
2022-05-10 | Journal article
DOI: 10.1038/s12276-022-00771-7
Contributors: Tao Zhu; Hong Zhang; Sijie Li; Kaifeng Wu; Yibing Yin; Xuemei Zhang
Source: check_circle
Crossref

IL-6 Prevents Lung Macrophage Death and Lung Inflammation Injury by Inhibiting GSDME- and GSDMD-Mediated Pyroptosis during Pneumococcal Pneumosepsis

Microbiology Spectrum
2022-04-27 | Journal article
DOI: 10.1128/spectrum.02049-21
Contributors: Xuemei Gou; Wenchun Xu; Yusi Liu; Yang Peng; Wenlong Xu; Yibing Yin; Xuemei Zhang; Fikri Y. Avci
Source: check_circle
Crossref

IL-4 plays an essential role in DnaJ-ΔA146Ply-mediated immunoprotection against Streptococcus pneumoniae in mice

Molecular Immunology
2022-03 | Journal article
DOI: 10.1016/j.molimm.2022.01.010
Contributors: Yi Hu; Lian Li; Wenchun Xu; Kaifeng Wu; Jiangming Xiao; Yang Peng; Yusi Liu; Yibing Yin; Xuemei Zhang
Source: check_circle
Crossref

Biomineralization improves the stability of a Streptococcus pneumoniae protein vaccine at high temperatures

Nanomedicine
2021-08 | Journal article
DOI: 10.2217/nnm-2021-0023
Part of ISSN: 1743-5889
Part of ISSN: 1748-6963
Source: Self-asserted source
Xuemei Zhang

Interleukin-4 protects mice against lethal influenza and Streptococcus pneumoniae co-infected pneumonia

Clinical and Experimental Immunology
2021-08-18 | Journal article
DOI: 10.1111/cei.13628
Contributors: Yang Peng; Xiaofang Wang; Hong Wang; Wenchun Xu; Kaifeng Wu; Xuemei Go; Yibing Yin; Xuemei Zhang
Source: check_circle
Crossref

Protective efficacy of mucosal and subcutaneous immunization with DnaJ-ΔA146Ply against influenza and Streptococcus pneumoniae co-infection in mice

Microbes and Infection
2021-03 | Journal article
DOI: 10.1016/j.micinf.2021.104813
Part of ISSN: 1286-4579
Source: Self-asserted source
Xuemei Zhang

Streptococcus pneumoniae aminopeptidase N regulates dendritic cells that attenuates type‐2 airway inflammation in murine allergic asthma

British Journal of Pharmacology
2020-11 | Journal article
DOI: 10.1111/bph.15216
Part of ISSN: 0007-1188
Part of ISSN: 1476-5381
Source: Self-asserted source
Xuemei Zhang

Combination of Detoxified Pneumolysin Derivative ΔA146Ply and Berbamine as a Treatment Approach for Breast Cancer

Molecular Therapy - Oncolytics
2020-09 | Journal article
DOI: 10.1016/j.omto.2020.06.015
Part of ISSN: 2372-7705
Source: Self-asserted source
Xuemei Zhang

Cytosolic mtDNA released from pneumolysin-damaged mitochondria triggers IFN-β production in epithelial cells

Canadian Journal of Microbiology
2020-07 | Journal article
DOI: 10.1139/cjm-2019-0481
Part of ISSN: 0008-4166
Part of ISSN: 1480-3275
Source: Self-asserted source
Xuemei Zhang

Streptococcus pneumoniae Endopeptidase O Promotes the Clearance of Staphylococcus aureus and Streptococcus pneumoniae via SH2 Domain-Containing Inositol Phosphatase 1-Mediated Complement Receptor 3 Upregulation

Frontiers in Cellular and Infection Microbiology
2020-07-17 | Journal article
DOI: 10.3389/fcimb.2020.00358
Part of ISSN: 2235-2988
Source: Self-asserted source
Xuemei Zhang

IL-6 During Influenza-Streptococcus pneumoniae Co-Infected Pneumonia—A Protector

Frontiers in Immunology
2020-01-21 | Journal article
DOI: 10.3389/fimmu.2019.03102
Part of ISSN: 1664-3224
Source: Self-asserted source
Xuemei Zhang

Progranulin Mediates Proinflammatory Responses in Systemic Lupus Erythematosus: Implications for the Pathogenesis of Systemic Lupus Erythematosus

Journal of Interferon & Cytokine Research
2020-01-01 | Journal article
DOI: 10.1089/jir.2019.0047
Part of ISSN: 1079-9907
Part of ISSN: 1557-7465
Source: Self-asserted source
Xuemei Zhang

Streptococcus pneumoniae PepO promotes host anti-infection defense via autophagy in a Toll-like receptor 2/4 dependent manner

Virulence
2020-01-01 | Journal article
DOI: 10.1080/21505594.2020.1739411
Part of ISSN: 2150-5594
Part of ISSN: 2150-5608
Source: Self-asserted source
Xuemei Zhang

Mast cell degranulation impairs pneumococcus clearance in mice via IL-6 dependent and TNF-α independent mechanisms

World Allergy Organization Journal
2019 | Journal article
DOI: 10.1016/j.waojou.2019.100028
Part of ISSN: 1939-4551
Source: Self-asserted source
Xuemei Zhang

miR-29b Reverses T helper 1 cells/T helper 2 cells Imbalance and Alleviates Airway Eosinophils Recruitment in OVA-Induced Murine Asthma by Targeting Inducible Co-Stimulator

International Archives of Allergy and Immunology
2019 | Journal article
DOI: 10.1159/000501686
Part of ISSN: 1018-2438
Part of ISSN: 1423-0097
Source: Self-asserted source
Xuemei Zhang

Type I IFN expression is stimulated by cytosolic Mt DNA released from pneumolysin‐damaged mitochondria via the STING signaling pathway in macrophages

The FEBS Journal
2019-12 | Journal article
DOI: 10.1111/febs.15001
Part of ISSN: 1742-464X
Part of ISSN: 1742-4658
Source: Self-asserted source
Xuemei Zhang

Progranulin Decreases Susceptibility toStreptococcus pneumoniaein Influenza and Protects against Lethal Coinfection

The Journal of Immunology
2019-10-15 | Journal article
DOI: 10.4049/jimmunol.1900248
Part of ISSN: 0022-1767
Part of ISSN: 1550-6606
Source: Self-asserted source
Xuemei Zhang

Type I interferon induced by DNA of nontypeable Haemophilus influenza modulates inflammatory cytokine profile to promote susceptibility to this bacterium

International Immunopharmacology
2019-09 | Journal article
DOI: 10.1016/j.intimp.2019.105710
Part of ISSN: 1567-5769
Source: Self-asserted source
Xuemei Zhang

Pneumococcal LytR Protein Is Required for the Surface Attachment of Both Capsular Polysaccharide and Teichoic Acids: Essential for Pneumococcal Virulence

Frontiers in Microbiology
2018-06-13 | Journal article
DOI: 10.3389/fmicb.2018.01199
Part of ISSN: 1664-302X
Source: Self-asserted source
Xuemei Zhang

Nontypeable Haemophilus influenzae DNA stimulates type I interferon expression via STING signaling pathway

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
2018-04 | Journal article
DOI: 10.1016/j.bbamcr.2018.01.011
Part of ISSN: 0167-4889
Source: Self-asserted source
Xuemei Zhang

Expression of Toll-Like Receptor 2 by Dendritic Cells Is Essential for the DnaJ-ΔA146Ply-Mediated Th1 Immune Response against Streptococcus pneumoniae

Infection and Immunity
2018-03 | Journal article
DOI: 10.1128/iai.00651-17
Part of ISSN: 0019-9567
Part of ISSN: 1098-5522
Source: Self-asserted source
Xuemei Zhang

Engineering detoxified pneumococcal pneumolysin derivative ΔA146PLY for self-biomineralization of calcium phosphate: Assessment of their protective efficacy in murine infection models

Biomaterials
2018-02 | Journal article
DOI: 10.1016/j.biomaterials.2017.11.018
Part of ISSN: 0142-9612
Source: Self-asserted source
Xuemei Zhang

Streptococcus pneumoniae Attenuated Strain SPY1 with an Artificial Mineral Shell Induces Humoral and Th17 Cellular Immunity and Protects Mice against Pneumococcal Infection

Frontiers in Immunology
2018-01-11 | Journal article
DOI: 10.3389/fimmu.2017.01983
Part of ISSN: 1664-3224
Source: Self-asserted source
Xuemei Zhang

Osteopontin is Critical for Hyperactive mTOR-Induced Tumorigenesis in Oral Squamous Cell Carcinoma

Journal of Cancer
2017 | Journal article
DOI: 10.7150/jca.18031
Part of ISSN: 1837-9664
Source: Self-asserted source
Xuemei Zhang

Interleukin-17A Aggravates Middle Ear Injury Induced by Streptococcus pneumoniae through the p38 Mitogen-Activated Protein Kinase Signaling Pathway

Infection and Immunity
2017-10 | Journal article
DOI: 10.1128/iai.00438-17
Part of ISSN: 0019-9567
Part of ISSN: 1098-5522
Source: Self-asserted source
Xuemei Zhang

Purified Streptococcus pneumoniae Endopeptidase O (PepO) Enhances Particle Uptake by Macrophages in a Toll-Like Receptor 2- and miR-155-Dependent Manner

Infection and Immunity
2017-04 | Journal article
DOI: 10.1128/iai.01012-16
Part of ISSN: 0019-9567
Part of ISSN: 1098-5522
Source: Self-asserted source
Xuemei Zhang

The critical role of myeloperoxidase in Streptococcus pneumoniae clearance and tissue damage during mouse acute otitis media

Innate Immunity
2017-04 | Journal article
DOI: 10.1177/1753425917693907
Part of ISSN: 1753-4259
Part of ISSN: 1753-4267
Source: Self-asserted source
Xuemei Zhang

DnaJ (hsp40) of Streptococcus pneumoniae is involved in bacterial virulence and elicits a strong natural immune reaction via PI3K/JNK

Molecular Immunology
2017-03 | Journal article
DOI: 10.1016/j.molimm.2017.01.021
Part of ISSN: 0161-5890
Source: Self-asserted source
Xuemei Zhang

Subcutaneous immunization with Streptococcus pneumoniae GAPDH confers effective protection in mice via TLR2 and TLR4

Molecular Immunology
2017-03 | Journal article
DOI: 10.1016/j.molimm.2017.01.002
Part of ISSN: 0161-5890
Source: Self-asserted source
Xuemei Zhang

ComE, an Essential Response Regulator, Negatively Regulates the Expression of the Capsular Polysaccharide Locus and Attenuates the Bacterial Virulence in Streptococcus pneumoniae

Frontiers in Microbiology
2017-03-07 | Journal article
DOI: 10.3389/fmicb.2017.00277
Part of ISSN: 1664-302X
Source: Self-asserted source
Xuemei Zhang

Pneumococcal DnaJ modulates dendritic cell-mediated Th1 and Th17 immune responses through Toll-like receptor 4 signaling pathway

Immunobiology
2017-02 | Journal article
DOI: 10.1016/j.imbio.2016.08.013
Part of ISSN: 0171-2985
Source: Self-asserted source
Xuemei Zhang

TLR2 promotes macrophage recruitment and Streptococcus pneumoniae clearance during mouse otitis media

Pediatric Research
2016-12 | Journal article
DOI: 10.1038/pr.2016.154
Part of ISSN: 0031-3998
Part of ISSN: 1530-0447
Source: Self-asserted source
Xuemei Zhang

Attenuated Streptococcus pneumoniae vaccine candidate SPY1 promotes dendritic cell activation and drives a Th1/Th17 response

Immunology Letters
2016-11 | Journal article
DOI: 10.1016/j.imlet.2016.08.008
Part of ISSN: 0165-2478
Source: Self-asserted source
Xuemei Zhang

Progranulin Plays a Central Role in Host Defense during Sepsis by Promoting Macrophage Recruitment

American Journal of Respiratory and Critical Care Medicine
2016-11-15 | Journal article
DOI: 10.1164/rccm.201601-0056oc
Part of ISSN: 1073-449X
Part of ISSN: 1535-4970
Source: Self-asserted source
Xuemei Zhang

SCCmec-associated psm-mec mRNA promotes Staphylococcus epidermidis biofilm formation

Antonie van Leeuwenhoek
2016-10 | Journal article
DOI: 10.1007/s10482-016-0741-2
Part of ISSN: 0003-6072
Part of ISSN: 1572-9699
Source: Self-asserted source
Xuemei Zhang

CpsR, a GntR family regulator, transcriptionally regulates capsular polysaccharide biosynthesis and governs bacterial virulence in Streptococcus pneumoniae

Scientific Reports
2016-07 | Journal article
DOI: 10.1038/srep29255
Part of ISSN: 2045-2322
Source: Self-asserted source
Xuemei Zhang

Streptococcus pneumoniae Endopeptidase O (PepO) Elicits a Strong Innate Immune Response in Mice via TLR2 and TLR4 Signaling Pathways

Frontiers in Cellular and Infection Microbiology
2016-02-29 | Journal article
DOI: 10.3389/fcimb.2016.00023
Part of ISSN: 2235-2988
Source: Self-asserted source
Xuemei Zhang

IL-27 enhances innate immunity of human pulmonary fibroblasts and epithelial cells through upregulation of TLR4 expression

American Journal of Physiology-Lung Cellular and Molecular Physiology
2016-01-15 | Journal article
DOI: 10.1152/ajplung.00307.2015
Part of ISSN: 1040-0605
Part of ISSN: 1522-1504
Source: Self-asserted source
Xuemei Zhang

DNA transducer-triggered signal switch for visual colorimetric bioanalysis

Scientific Reports
2015-09 | Journal article
DOI: 10.1038/srep11190
Part of ISSN: 2045-2322
Source: Self-asserted source
Xuemei Zhang

Progranulin is preferentially expressed in patients with psoriasis vulgaris and protects mice from psoriasis-like skin inflammation

Immunology
2015-06 | Journal article
DOI: 10.1111/imm.12446
Part of ISSN: 0019-2805
Source: Self-asserted source
Xuemei Zhang

Interleukin 4 Deficiency Reverses Development of Secondary Pseudomonas aeruginosa Pneumonia During Sepsis-Associated Immunosuppression

Journal of Infectious Diseases
2015-05-15 | Journal article
DOI: 10.1093/infdis/jiu668
Part of ISSN: 0022-1899
Part of ISSN: 1537-6613
Source: Self-asserted source
Xuemei Zhang
grade
Preferred source (of 2)‎

c-Jun N-terminal kinase and Akt signalling pathways regulating tumour necrosis factor-α-induced interleukin-32 expression in human lung fibroblasts: implications in airway inflammation

Immunology
2015-02 | Journal article
DOI: 10.1111/imm.12374
Part of ISSN: 0019-2805
Source: Self-asserted source
Xuemei Zhang

Compound 48/80 acts as a potent mucosal adjuvant for vaccination against Streptococcus pneumoniae infection in young mice

Vaccine
2015-02 | Journal article
DOI: 10.1016/j.vaccine.2015.01.013
Part of ISSN: 0264-410X
Source: Self-asserted source
Xuemei Zhang

Pneumococcal wall teichoic acid is required for the pathogenesis of Streptococcus pneumoniae in murine models

Journal of Microbiology
2015-02 | Journal article
DOI: 10.1007/s12275-015-4616-4
Part of ISSN: 1225-8873
Part of ISSN: 1976-3794
Source: Self-asserted source
Xuemei Zhang

Mucosal Immunization with the Live Attenuated Vaccine SPY1 Induces Humoral and Th2-Th17-Regulatory T Cell Cellular Immunity and Protects against Pneumococcal Infection

Infection and Immunity
2015-01 | Journal article
DOI: 10.1128/iai.02334-14
Part of ISSN: 0019-9567
Part of ISSN: 1098-5522
Source: Self-asserted source
Xuemei Zhang
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