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Employment (6)

Leiden University Medical Center: Leiden, NL

2005 to present | Associate Professor/Group leader (Molecular Cell Biology)
Employment
Source: Self-asserted source
Aart G Jochemsen

Leiden University Medical Center: Leiden, NL

1999 to 2005 | Assistent Professor/Group leader (Molecular Cell Biology)
Employment
Source: Self-asserted source
Aart G Jochemsen

Leiden University Medical Center: Leiden, NL

1989 to 1999 | Postdoctoral Scientist/Group leader (Molecular Cell Biology)
Employment
Source: Self-asserted source
Aart G Jochemsen

University of California Irvine: Irvine, CA, US

1988-08-31 to 1989-08-30 | Postdoctoral Fellow (Microbiology and Medical Genetics)
Employment
Source: Self-asserted source
Aart G Jochemsen

University Leiden: Leiden, NL

1987-07-01 to 1988-08-30 | Postdoctoral Research Scientist (Medical Biochemistry)
Employment
Source: Self-asserted source
Aart G Jochemsen

Universiteit Leiden: Leiden, Zuid-Holland, NL

1983-01-01 to 1987-06-30 | PhD Student (Medical Biochemistry)
Employment
Source: Self-asserted source
Aart G Jochemsen

Education and qualifications (1)

Vrije Universiteit Amsterdam: Amsterdam, Noord-Holland, NL

1976-07 to 1982-12 | Drs
Education
Source: Self-asserted source
Aart G Jochemsen

Funding (6)

Functions of Mdmx in melanoma: identifying new targets for therapeutic intervention

2013 to 2017 | Grant
dutch Cancer Society (Amsterdam, NL)
GRANT_NUMBER:

UL 2013-5757
Source: Self-asserted source
Aart G Jochemsen

Cross-talk between p53 and TGF-beta pathways in tumour invasion

2009-04-01 to 2012-06-30 | Grant
Worldwide Cancer Research (St Andrews, GB)
URL: https://grants.uberresearch.com/100004435/WCR-09-0073/Cross-talk-between-p53-and-TGF-beta-pathways-in-tumour-invasion
GRANT_NUMBER:

WCR-09-0073
Source: Self-asserted source
Aart G Jochemsen via DimensionsWizard

Functions and Regulation of Hdmx in carcinogenesis

2006 to 2010 | Grant
Dutch Cancer Society (Amsterdam, NL)
Source: Self-asserted source
Aart G Jochemsen

Functions and mechanisms of altered Hdmx expression in human carcinogenesis

2005-10-01 to 2008-09-30 | Grant
Worldwide Cancer Research (St Andrews, GB)
URL: https://grants.uberresearch.com/100004435/WCR-05-0273/Functions-and-mechanisms-of-altered-Hdmx-expression-in-human-carcinogenesis
GRANT_NUMBER:

WCR-05-0273
Source: Self-asserted source
Aart G Jochemsen via DimensionsWizard

A structure-function analysis of the Mdmx protein

2001 to present | Grant
Association for International Cancer Research (St Andrews, GB)
GRANT_NUMBER:

01-276
Source: Self-asserted source
Aart G Jochemsen

Functional analysis of the Mdmx protein in comparison with Mdm2, with emphasis on the interactions with p73 and p53

Grant
Association for International Cancer Research (St. Andrews, GB)
GRANT_NUMBER:

98-256
Source: Self-asserted source
Aart G Jochemsen

Works (9)

Comparative phosphoproteome analysis of primary and metastatic uveal melanoma cell lines

2023-12-08 | Preprint
DOI: 10.1101/2023.12.06.570407
Contributors: K. Glinkina; R. Gonzalez Prieto; A.F.A.S. Teunisse; M.C. Gelmi; M.J. Jager; A.C.O. Vertegaal; A.G. Jochemsen
Source: check_circle
Crossref

Patient-derived zebrafish xenografts of uveal melanoma reveal ferroptosis as a drug target

Cell Death Discovery
2023-06-16 | Journal article
DOI: 10.1038/s41420-023-01446-6
Contributors: Arwin Groenewoud; Jie Yin; Maria Chiara Gelmi; Samar Alsafadi; Fariba Nemati; Didier Decaudin; Sergio Roman-Roman; Helen Kalirai; Sarah E. Coupland; Aart G. Jochemsen et al.
Source: check_circle
Crossref

Zebrafish Patient-Derived Xenograft Model as a Preclinical Platform for Uveal Melanoma Drug Discovery

Pharmaceuticals
2023-04-15 | Journal article
DOI: 10.3390/ph16040598
Contributors: Jie Yin; Gangyin Zhao; Helen Kalirai; Sarah E. Coupland; Aart G. Jochemsen; Gabriel Forn-Cuní; Annemijn P. A. Wierenga; Martine J. Jager; B. Ewa Snaar-Jagalska; Arwin Groenewoud
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Crossref
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FAK Inhibitor-Based Combinations with MEK or PKC Inhibitors Trigger Synergistic Antitumor Effects in Uveal Melanoma

Cancers
2023-04-13 | Journal article
DOI: 10.3390/cancers15082280
Contributors: Malcy Tarin; Fariba Némati; Didier Decaudin; Christine Canbezdi; Benjamin Marande; Lisseth Silva; Héloïse Derrien; Aart G. Jochemsen; Sophie Gardrat; Sophie Piperno-Neumann et al.
Source: check_circle
Crossref
grade
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Patient-derived zebrafish xenografts of uveal melanoma reveal ferroptosis as a drug target

2022-11-10 | Preprint
DOI: 10.21203/rs.3.rs-2113688/v1
Contributors: Arwin Groenewoud; Jie Yin; Maria-Chiara Gelmi; Samar Alsafadi; Fariba Nemati; Didier Decaudin; Sergio Roman-Roman; Helen Kalirai; Sarah Coupland; Aart Jochemsen et al.
Source: check_circle
Crossref

Expression of HDACs 1, 3 and 8 Is Upregulated in the Presence of Infiltrating Lymphocytes in Uveal Melanoma

Cancers
2021-08-18 | Journal article
DOI: 10.3390/cancers13164146
Contributors: Zahra Souri; Aart G. Jochemsen; Annemijn P. A. Wierenga; Wilma G. M. Kroes; Rob M. Verdijk; Pieter A. van der Velden; Gregorius P. M. Luyten; Martine J. Jager
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Analysis of CRISPR‐Cas9 screens identifies genetic dependencies in melanoma

Pigment Cell & Melanoma Research
2021-01 | Journal article
DOI: 10.1111/pcmr.12919
Contributors: Eirini Christodoulou; Mamunur Rashid; Clare Pacini; Alastair Droop; Holly Robertson; Tim van Groningen; Amina F. A. S. Teunisse; Francesco Iorio; Aart G. Jochemsen; David J. Adams et al.
Source: check_circle
Crossref

Breast cancer dormancy is associated with a 4NG1 state and not senescence

2020-11-21 | Preprint
DOI: 10.1101/2020.11.20.367698
Contributors: Chloé Prunier; Ania Alay; Michiel van Dijk; Kelly L. Ammerlaan; Sharon van Gelderen; Dieuwke L. Marvin; Amina Teunisse; Roderick C. Slieker; Karoly Szuhai; A.G. Jochemsen et al.
Source: check_circle
Crossref

Selective PKCδ Inhibitor B106 Elicits Uveal Melanoma Growth Inhibitory Effects Independent of Activated PKC Isoforms

ACS Chemical Biology
2019-01-18 | Journal article
DOI: 10.1021/acschembio.8b00292
Contributors: Renier Heijkants; Amina Teunisse; Jelle de Vries; Huib Ovaa; Aart Jochemsen
Source: check_circle
Crossref
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