Personal information

蛋白质化学修饰, 蛋白质功能进化, 噬菌体筛选
China

Biography

中国科学技术大学:合肥,安徽,中国
2016-07-至今

Activities

Employment (3)

中国科学技术大学: 合肥, 安徽, CN

2016-07-12 to present | 教授 (生命科学学院)
Employment
Source: Self-asserted source
Ji-Shen Zheng

中国科学院合肥物质科学研究院: 合肥, 安徽, CN

2014-03-01 to 2016-07-11 | 副研究员 (强磁场科学中心)
Employment
Source: Self-asserted source
Ji-Shen Zheng

清华大学: 北京, 北京, CN

2012-07-10 to 2014-03-01 | 博士后助理研究员 (化学系)
Employment
Source: Self-asserted source
Ji-Shen Zheng

Education and qualifications (1)

中国科学技术大学: 合肥, 安徽, CN

2006-09-01 to 2012-07-01 | 博士研究生 (化学系)
Education
Source: Self-asserted source
Ji-Shen Zheng

Works (50 of 66)

Items per page:
Page 1 of 2

Mechanically Triggered Protein Desulfurization

Journal of the American Chemical Society
2025-02-05 | Journal article
Contributors: Dongyang Han; Yan Cui; Xiangyu Deng; Chuntong Li; Xianglai Zhu; Bingji Wang; Guo-Chao Chu; Zhipeng A. Wang; Shan Tang; Ji-Shen Zheng et al.
Source: check_circle
Crossref

Biomimetic Folding Strategies for Chemical Synthesis of Disulfide‐Bonded Peptides and Proteins

ChemBioChem
2024-12-16 | Journal article
Contributors: Guoxia Yu; Shijun Zou; Ji‐Shen Zheng
Source: check_circle
Crossref

Enhanced native chemical ligation by peptide conjugation in trifluoroacetic acid

Science Advances
2024-07-19 | Journal article
Contributors: Dong-Liang Huang; Wu-Chen Guo; Wei-Wei Shi; Yun-Pu Gao; Yong-Kang Zhou; Long-Jie Wang; Chen Wang; Shan Tang; Lei Liu; Ji-Shen Zheng
Source: check_circle
Crossref

L‐Glycosidase‐Cleavable Natural Glycans Facilitate the Chemical Synthesis of Correctly Folded Disulfide‐Bonded D‐Proteins

Angewandte Chemie
2024-02-26 | Journal article
Contributors: Weiwei Shi; Tongyue Wang; Ziyi Yang; Yuxiang Ren; Dongyang Han; Yupeng Zheng; Xiangyu Deng; Shan Tang; Ji‐Shen Zheng
Source: check_circle
Crossref

L‐Glycosidase‐Cleavable Natural Glycans Facilitate the Chemical Synthesis of Correctly Folded Disulfide‐Bonded D‐Proteins

Angewandte Chemie International Edition
2024-02-26 | Journal article
Contributors: Weiwei Shi; Tongyue Wang; Ziyi Yang; Yuxiang Ren; Dongyang Han; Yupeng Zheng; Xiangyu Deng; Shan Tang; Ji‐Shen Zheng
Source: check_circle
Crossref

Backbone‐Installed Split Intein‐Assisted Ligation for the Chemical Synthesis of Mirror‐Image Proteins

Angewandte Chemie
2023-08-14 | Journal article
Contributors: Baochang Zhang; Yupeng Zheng; Guochao Chu; Xiangyu Deng; Tongyue Wang; Weiwei Shi; Yongkang Zhou; Shan Tang; Ji‐Shen Zheng; Lei Liu
Source: check_circle
Crossref

Backbone‐Installed Split Intein‐Assisted Ligation for the Chemical Synthesis of Mirror‐Image Proteins

Angewandte Chemie International Edition
2023-08-14 | Journal article
Contributors: Baochang Zhang; Yupeng Zheng; Guochao Chu; Xiangyu Deng; Tongyue Wang; Weiwei Shi; Yongkang Zhou; Shan Tang; Ji‐Shen Zheng; Lei Liu
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Chemically Synthetic d-Sortase Enables Enzymatic Ligation of d-Peptides

Organic Letters
2023-07-07 | Journal article
Contributors: Ruichao Ding; Wei-Wei Shi; Ji-Shen Zheng
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Advances in peptide synthesis

Peptide and Peptidomimetic Therapeutics: From Bench to Bedside
2022 | Book chapter
EID:

2-s2.0-85142733059

Contributors: Wang, Z.A.; Zheng, J.-S.
Source: Self-asserted source
Ji-Shen Zheng via Scopus - Elsevier

Removable Backbone Modification (RBM) Strategy for the Chemical Synthesis of Hydrophobic Peptides/Proteins

Methods in Molecular Biology
2022 | Book chapter
EID:

2-s2.0-85132951780

Part of ISSN: 19406029 10643745
Contributors: Huang, D.-L.; Li, Y.; Zheng, J.-S.
Source: Self-asserted source
Ji-Shen Zheng via Scopus - Elsevier

Total Chemical Synthesis of Correctly Folded Disulfide-Rich Proteins Using a Removable O-Linked β-N-Acetylglucosamine Strategy

Journal of the American Chemical Society
2022-01-12 | Journal article
Part of ISSN: 0002-7863
Part of ISSN: 1520-5126
Source: Self-asserted source
Ji-Shen Zheng
grade
Preferred source (of 3)‎

Sarcolipin alters SERCA1a interdomain communication by impairing binding of both calcium and ATP

Scientific Reports
2021-12 | Journal article
Part of ISSN: 2045-2322
Source: Self-asserted source
Ji-Shen Zheng
grade
Preferred source (of 2)‎

Chemical Synthesis of a Full-Length G-Protein-Coupled Receptor β2-Adrenergic Receptor with Defined Modification Patterns at the C-Terminus

Journal of the American Chemical Society
2021-10-27 | Journal article
Part of ISSN: 0002-7863
Part of ISSN: 1520-5126
Source: Self-asserted source
Ji-Shen Zheng
grade
Preferred source (of 2)‎

A mirror-image protein-based information barcoding and storage technology

Science Bulletin
2021-08 | Journal article
Part of ISSN: 2095-9273
Source: Self-asserted source
Ji-Shen Zheng
grade
Preferred source (of 2)‎

A genetically encoded small-size fluorescent pair reveals allosteric conformational changes of G proteins upon its interaction with GPCRs by fluorescence lifetime based FRET

Chemical Communications
2020 | Journal article
Part of ISSN: 1359-7345
Part of ISSN: 1364-548X
Source: Self-asserted source
Ji-Shen Zheng
grade
Preferred source (of 2)‎

Chemical protein synthesis-assisted high-throughput screening strategies for D-peptides in drug discovery

Chinese Chemical Letters
2020 | Journal article
EID:

2-s2.0-85084386085

Part of ISSN: 10018417
Contributors: Li, Y.; Cao, X.; Tian, C.; Zheng, J.-S.
Source: Self-asserted source
Ji-Shen Zheng via Scopus - Elsevier

The New Salicylaldehyde S,S-Propanedithioacetal Ester Enables N-to-C Sequential Native Chemical Ligation and Ser/Thr Ligation for Chemical Protein Synthesis

Journal of the American Chemical Society
2020-05-13 | Journal article
Part of ISSN: 0002-7863
Part of ISSN: 1520-5126
Source: Self-asserted source
Ji-Shen Zheng
grade
Preferred source (of 3)‎

Synthesis of Disulfide Surrogate Peptides Incorporating Large‐Span Surrogate Bridges Through a Native‐Chemical‐Ligation‐Assisted Diaminodiacid Strategy

Angewandte Chemie International Edition
2020-04-06 | Journal article
Part of ISSN: 1433-7851
Part of ISSN: 1521-3773
Source: Self-asserted source
Ji-Shen Zheng
grade
Preferred source (of 2)‎

Chemical Synthesis of Native S‐Palmitoylated Membrane Proteins through Removable‐Backbone‐Modification‐Assisted Ser/Thr Ligation

Angewandte Chemie International Edition
2020-03-23 | Journal article
Part of ISSN: 1433-7851
Part of ISSN: 1521-3773
Source: Self-asserted source
Ji-Shen Zheng
grade
Preferred source (of 2)‎

One-pot multi-segment condensation strategies for chemical protein synthesis

Organic & Biomolecular Chemistry
2019 | Journal article
Part of ISSN: 1477-0520
Part of ISSN: 1477-0539
Source: Self-asserted source
Ji-Shen Zheng
grade
Preferred source (of 2)‎

Recent advances in the chemical synthesis and semi-synthesis of poly-ubiquitin-based proteins and probes

Science China Chemistry
2019 | Journal article
EID:

2-s2.0-85061063266

Part of ISSN: 18691870 16747291
Contributors: Qi, Y.-K.; Si, Y.-Y.; Du, S.-S.; Liang, J.; Wang, K.-W.; Zheng, J.-S.
Source: Self-asserted source
Ji-Shen Zheng via Scopus - Elsevier

Thiirane linkers directed histone H2A diubiquitination suggests plasticity in 53BP1 recognition

Chemical Communications
2019 | Journal article
Part of ISSN: 1359-7345
Part of ISSN: 1364-548X
Source: Self-asserted source
Ji-Shen Zheng
grade
Preferred source (of 2)‎

Ligation of Soluble but Unreactive Peptide Segments in the Chemical Synthesis of Haemophilus Influenzae DNA Ligase

Angewandte Chemie International Edition
2019-08-26 | Journal article
Part of ISSN: 1433-7851
Part of ISSN: 1521-3773
Source: Self-asserted source
Ji-Shen Zheng
grade
Preferred source (of 2)‎

Channel activity of mirror-image M2 proton channel of influenza A virus is blocked by achiral or chiral inhibitors

Protein & Cell
2019-03 | Journal article
Part of ISSN: 1674-800X
Part of ISSN: 1674-8018
Source: Self-asserted source
Ji-Shen Zheng
grade
Preferred source (of 2)‎

Biochemical properties of K<sub>11,48</sub>-branched ubiquitin chains

Chinese Chemical Letters
2018 | Journal article
EID:

2-s2.0-85044532898

Part of ISSN: 10018417
Contributors: Liang, L.-J.; Si, Y.; Tang, S.; Huang, D.; Wang, Z.A.; Tian, C.; Zheng, J.-S.
Source: Self-asserted source
Ji-Shen Zheng via Scopus - Elsevier

Chemical (Semi-) Synthesis and Applications of Lysine Post-Translationally Modified Proteins,赖氨酸翻译后修饰蛋白质的化学(半)合成及其应用

Chinese Journal of Organic Chemistry
2018 | Journal article
EID:

2-s2.0-85060111850

Part of ISSN: 02532786
Contributors: Wang, Z.; Li, M.; Li, H.; Liu, Z.; Li, Y.; Zheng, J.-S.
Source: Self-asserted source
Ji-Shen Zheng via Scopus - Elsevier

Chemically synthesized histone H2A Lys13 di-ubiquitination promotes binding of 53BP1 to nucleosomes

Cell Research
2018 | Journal article
EID:

2-s2.0-85041678969

Part of ISSN: 17487838 10010602
Contributors: Li, J.-B.; Qi, Y.-K.; He, Q.-Q.; Ai, H.-S.; Liu, S.-L.; Wang, J.-X.; Zheng, J.-S.; Liu, L.; Tian, C.
Source: Self-asserted source
Ji-Shen Zheng via Scopus - Elsevier

One-pot ligation strategy for atypical ubiquitin chains synthesis by using the trifluoroacetamidomethyl-protected isopeptide-linked Ub (Tfacm-isoUb) unit

Tetrahedron Letters
2018 | Journal article
EID:

2-s2.0-85039719494

Part of ISSN: 18733581 00404039
Contributors: Si, Y.-Y.; Liang, L.-J.; Tang, S.; Qi, Y.-K.; Huang, Y.; Zheng, J.-S.
Source: Self-asserted source
Ji-Shen Zheng via Scopus - Elsevier

Reductive amination/alkylation reactions: The recent developments, progresses, and applications in protein chemical biology studies

Current Organic Synthesis
2018 | Journal article
EID:

2-s2.0-85055262880

Part of ISSN: 15701794
Contributors: Wang, Z.A.; Liang, Y.-Y.; Zheng, J.-S.
Source: Self-asserted source
Ji-Shen Zheng via Scopus - Elsevier

PI(4,5)P2 determines the threshold of mechanical force–induced B cell activation

Journal of Cell Biology
2018-07-02 | Journal article
Part of ISSN: 0021-9525
Part of ISSN: 1540-8140
Source: Self-asserted source
Ji-Shen Zheng
grade
Preferred source (of 2)‎

Chemically synthesized histone H2A Lys13 di-ubiquitination promotes binding of 53BP1 to nucleosomes

Cell Research
2018-02 | Journal article
Part of ISSN: 1001-0602
Part of ISSN: 1748-7838
Source: Self-asserted source
Ji-Shen Zheng

Erratum: Chemically synthesized histone H2A Lys13 di-ubiquitination promotes binding of 53BP1 to nucleosomes

Cell Research
2018-02 | Journal article
Part of ISSN: 1001-0602
Part of ISSN: 1748-7838
Source: Self-asserted source
Ji-Shen Zheng

Convergent Total Synthesis of Histone H2B Protein with Site-Specific Ubiquitination at Lys120

Synlett
2017 | Journal article
EID:

2-s2.0-85023759049

Part of ISSN: 14372096 09365214
Contributors: Qi, Y.-K.; He, Q.-Q.; Ai, H.-S.; Li, J.-B.; Zheng, J.-S.
Source: Self-asserted source
Ji-Shen Zheng via Scopus - Elsevier

Chemical synthesis of membrane proteins by the removable backbone modification method

Nature Protocols
2017-12 | Journal article
Part of ISSN: 1754-2189
Part of ISSN: 1750-2799
Source: Self-asserted source
Ji-Shen Zheng
grade
Preferred source (of 2)‎

Mirror-image polymerase chain reaction

Cell Discovery
2017-10-17 | Journal article
Contributors: Wenjun Jiang; Baochang Zhang; Chuyao Fan; Min Wang; Jiaxing Wang; Qiang Deng; Xianyu Liu; Ji Chen; Jishen Zheng; Lei Liu et al.
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Practical Chemical Synthesis of Atypical Ubiquitin Chains by Using an Isopeptide-Linked Ub Isomer

Angewandte Chemie International Edition
2017-10-16 | Journal article
Part of ISSN: 1433-7851
Source: Self-asserted source
Ji-Shen Zheng
grade
Preferred source (of 2)‎

Removable Backbone Modification Method for the Chemical Synthesis of Membrane Proteins

Accounts of Chemical Research
2017-05-16 | Journal article
Part of ISSN: 0001-4842
Part of ISSN: 1520-4898
Source: Self-asserted source
Ji-Shen Zheng
grade
Preferred source (of 3)‎

Chemical Synthesis of Diubiquitin-Based Photoaffinity Probes for Selectively Profiling Ubiquitin-Binding Proteins

Angewandte Chemie International Edition
2017-03-01 | Journal article
Part of ISSN: 1433-7851
Source: Self-asserted source
Ji-Shen Zheng
grade
Preferred source (of 2)‎

Chemical Synthesis of K34-Ubiquitylated H2B for Nucleosome Reconstitution and Single-Particle Cryo-Electron Microscopy Structural Analysis

ChemBioChem
2017-01-17 | Journal article
Part of ISSN: 1439-4227
Source: Self-asserted source
Ji-Shen Zheng
grade
Preferred source (of 2)‎

A novel bispecific peptide HIV-1 fusion inhibitor targeting the N-terminal heptad repeat and fusion peptide domains in gp41

Amino Acids
2016 | Journal article
EID:

2-s2.0-84986302008

Part of ISSN: 14382199 09394451
Contributors: Jiang, X.; Jia, Q.; Lu, L.; Yu, F.; Zheng, J.; Shi, W.; Cai, L.; Jiang, S.; Liu, K.
Source: Self-asserted source
Ji-Shen Zheng via Scopus - Elsevier

Efficient synthesis of longer Aβ peptides via removable backbone modification

Organic & Biomolecular Chemistry
2016 | Journal article
Part of ISSN: 1477-0520
Part of ISSN: 1477-0539
Source: Self-asserted source
Ji-Shen Zheng
grade
Preferred source (of 2)‎

Hmboff/on as a switchable thiol protecting group for native chemical ligation

Organic & Biomolecular Chemistry
2016 | Journal article
Part of ISSN: 1477-0520
Part of ISSN: 1477-0539
Source: Self-asserted source
Ji-Shen Zheng
grade
Preferred source (of 2)‎

Protein/peptide secondary structural mimics: Design, characterization, and modulation of protein-protein interactions

RSC Advances
2016 | Journal article
EID:

2-s2.0-84976866495

Part of ISSN: 20462069
Contributors: Wang, Z.A.; Ding, X.Z.; Tian, C.-L.; Zheng, J.-S.
Source: Self-asserted source
Ji-Shen Zheng via Scopus - Elsevier

The structural designs and property analysis of polyamide based structures as peptide secondary structure mimics

Progress in Chemistry
2016 | Journal article
EID:

2-s2.0-84992223593

Part of ISSN: 1005281X
Contributors: Wang, Z.; Tian, C.; Zheng, J.
Source: Self-asserted source
Ji-Shen Zheng via Scopus - Elsevier

Total chemical synthesis of photoactivatable proteins for light-controlled manipulation of antigen–antibody interactions

Chemical Science
2016 | Journal article
Part of ISSN: 2041-6520
Part of ISSN: 2041-6539
Source: Self-asserted source
Ji-Shen Zheng
grade
Preferred source (of 2)‎

Total synthesis of mambalgin-1/2/3 by two-segment hydrazide-based native chemical ligation

Journal of Peptide Science
2016-05 | Journal article
Part of ISSN: 1075-2617
Source: Self-asserted source
Ji-Shen Zheng
grade
Preferred source (of 2)‎

Robust Chemical Synthesis of Membrane Proteins through a General Method of Removable Backbone Modification

Journal of the American Chemical Society
2016-03-16 | Journal article
Part of ISSN: 0002-7863
Part of ISSN: 1520-5126
Source: Self-asserted source
Ji-Shen Zheng
grade
Preferred source (of 4)‎

A new strategy for total solid-phase synthesis of polymyxins

Tetrahedron Letters
2015 | Journal article
EID:

2-s2.0-84936985815

Part of ISSN: 18733581 00404039
Contributors: Xu, W.-L.; Cui, A.-L.; Hu, X.-X.; You, X.-F.; Li, Z.-R.; Zheng, J.-S.
Source: Self-asserted source
Ji-Shen Zheng via Scopus - Elsevier

An Fmoc-compatible method for synthesis of peptides containing photocaged aspartic acid or glutamic acid

Tetrahedron Letters
2015 | Journal article
EID:

2-s2.0-84933279972

Part of ISSN: 18733581 00404039
Contributors: Tang, S.; Cheng, J.-Y.; Zheng, J.-S.
Source: Self-asserted source
Ji-Shen Zheng via Scopus - Elsevier

The recent developments and applications of the traceless-Staudinger reaction in chemical biology study

RSC Advances
2015 | Journal article
EID:

2-s2.0-84952359800

Part of ISSN: 20462069
Contributors: Wang, Z.-P.A.; Tian, C.-L.; Zheng, J.-S.
Source: Self-asserted source
Ji-Shen Zheng via Scopus - Elsevier
Items per page:
Page 1 of 2

Peer review (17 reviews for 9 publications/grants)

Review activity for Angewandte Chemie. (2)
Review activity for Biochemistry. (2)
Review activity for Bioconjugate chemistry. (1)
Review activity for ChemBioChem. (4)
Review activity for Current opinion in chemical biology. (2)
Review activity for Journal of organic chemistry. (2)
Review activity for Nature chemistry. (1)
Review activity for Nature communications (2)
Review activity for Organic letters. (1)