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Employment (1)

University of Virginia Hospital: Charlottesville, VA, US

2015-01-02 to present | Associate Professor (Pathology)
Employment
Source: Self-asserted source
Chance John Luckey

Education and qualifications (4)

Harvard Medical School: Boston, MA, US

Fellowship in Transfusion Medicine (Pathology)
Education
Source: Self-asserted source
Chance John Luckey

Brigham and Women's Hospital: Boston, MA, US

Clinical Pathology Residency (Pathology)
Education
Source: Self-asserted source
Chance John Luckey

University of Virginia: Charlottesville, VA, US

1992 to 2001 | MD PhD (School of Medicine and Microbiology)
Education
Source: Self-asserted source
Chance John Luckey

University of Georgia: Athens, Georgia, US

1987 to 1991 | BS
Education
Source: Self-asserted source
Chance John Luckey

Funding (8)

A spatially organized microphysiological model of a human lymph node

2019-09-17 to 2024-06-30 | Grant
National Institute of Biomedical Imaging and Bioengineering (Bethesda, US)
GRANT_NUMBER: U01EB029127
Source: Self-asserted source
Chance John Luckey via DimensionsWizard

Signaling and Transcriptional Control of T Follicular Helper Cells and RBC Alloimmunization

2018-09-01 to 2020-08-31 | Grant
National Heart Lung and Blood Institute (Bethesda, US)
GRANT_NUMBER: R21HL143025
Source: Self-asserted source
Chance John Luckey via DimensionsWizard

Immunobiology of Transfusion

2017-09-01 to 2022-06-30 | Grant
National Heart Lung and Blood Institute (Bethesda, US)
GRANT_NUMBER: P01HL132819
Source: Self-asserted source
Chance John Luckey via DimensionsWizard

Cyokine control of red blood cell alloimmunization

2016-12-15 to 2020-11-30 | Grant
National Heart Lung and Blood Institute (Bethesda, US)
GRANT_NUMBER: R01HL134691
Source: Self-asserted source
Chance John Luckey via DimensionsWizard

Transcriptional Control of Memory Responses to Red Blood Cell Alloimmunization

2013-08-01 to 2015-12-31 | Grant
National Heart Lung and Blood Institute (Bethesda, US)
GRANT_NUMBER: R21HL119652
Source: Self-asserted source
Chance John Luckey via DimensionsWizard

Cytokine control of Red Blood Cell Alloimmunization

2012-02-15 to 2013-12-31 | Grant
National Heart Lung and Blood Institute (Bethesda, US)
GRANT_NUMBER: R21HL111866
Source: Self-asserted source
Chance John Luckey via DimensionsWizard

Pou6f1 transcriptional control of memory CD8+ T cells

2011-06-01 to 2013-05-31 | Grant
National Institute of Allergy and Infectious Diseases (Bethesda, US)
GRANT_NUMBER: R21AI095635
Source: Self-asserted source
Chance John Luckey via DimensionsWizard

The Role of FcGamma-Rllb in Memory T cell self-renewal

2005-07-01 to 2010-05-31 | Grant
National Institute of Allergy and Infectious Diseases (Bethesda, US)
GRANT_NUMBER: K08AI063386
Source: Self-asserted source
Chance John Luckey via DimensionsWizard

Works (33)

Engineered human lymph node stroma model for examining interstitial fluid flow and T cell egress

2024-12-07 | Preprint
Contributors: Jennifer H Hammel; Abhinav Arneja; Jessica Cunningham; Maosen Wang; Sophia Schumaecker; Yamilet Macias Orihuela; Tochukwu Ozulumba; Jonathan Zatorski; Thomas J Braciale; Chance John Luckey et al.
Source: check_circle
Crossref

Mitigating reactive oxygen species production and increasing gel porosity improves lymphocyte motility and fibroblast spreading in photocrosslinked gelatin-thiol hydrogels

2024-01-15 | Preprint
Contributors: Tochukwu Ozulumba; Jonathan M. Zatorski; Abhinav Arneja; Jennifer H. Hammel; Thomas J. Braciale; Chance J. Luckey; Jennifer M. Munson; Rebecca R. Pompano
Source: check_circle
Crossref

Antibody-mediated antigen loss switches augmented immunity to antibody-mediated immunosuppression

Blood
2023-09-21 | Journal article
Contributors: Ryan P. Jajosky; Kashyap R. Patel; Jerry William L. Allen; Patricia E. Zerra; Satheesh Chonat; Diyoly Ayona; Cheryl L. Maier; Dominique Morais; Shang-Chuen Wu; C. John Luckey et al.
Source: check_circle
Crossref

The role of RBC antigen transgene integration sites on RBC biology in mice

Transfusion
2023-01 | Journal article
Contributors: Arijita Jash; Ariel M. Hay; J. Baodan Collins; Jinho Heo; Chance John Luckey; Krystalyn E. Hudson; James C. Zimring
Source: check_circle
Crossref

Prior Immunization to an Intracellular Antigen Enhances Subsequent Red Blood Cell Alloimmunization in Mice

Blood
2023-01-13 | Journal article
Contributors: Ryan Philip Jajosky; Seema R Patel; Shang-Chuen Wu; Kashyap R Patel; Mischa Li Covington; Mary L Vallecillo-Zúniga; Diyoly Ayona; Ashley Bennett; Chance John Luckey; Krystalyn E Hudson et al.
Source: check_circle
Crossref

Antibodies to Low-Copy Number RBC Alloantigen Convert a Tolerogenic Stimulus to an Immunogenic Stimulus in Mice

Frontiers in Immunology
2021 | Journal article
EID:

2-s2.0-85103315572

Part of ISSN: 16643224
Contributors: Jash, A.; Usaneerungrueng, C.; Howie, H.L.; Qiu, A.; Luckey, C.J.; Zimring, J.C.; Hudson, K.E.
Source: Self-asserted source
Chance John Luckey via Scopus - Elsevier

Iron control of erythroid microtubule cytoskeleton as a potential target in treatment of iron-restricted anemia

Nature Communications
2021 | Journal article
EID:

2-s2.0-85102494055

Part of ISSN: 20411723
Contributors: Goldfarb, A.N.; Freeman, K.C.; Sahu, R.K.; Elagib, K.E.; Holy, M.; Arneja, A.; Polanowska-Grabowska, R.; Gru, A.A.; White, Z.; Khalil, S. et al.
Source: Self-asserted source
Chance John Luckey via Scopus - Elsevier

Innate and adaptive immunity to transfused allogenic red blood cells in mice requires MyD88

2021-08-25 | Preprint
Contributors: Arielle Soldatenko; Laura R. Hoyt; Lan Xu; Samuele Calabro; Steven M. Lewis; Antonia E. Gallman; Krystalyn E. Hudson; Sean R. Stowell; Chance J. Luckey; James C. Zimring et al.
Source: check_circle
Crossref

Poly(I:C) causes failure of immunoprophylaxis to red blood cells expressing the KEL glycoprotein in mice

Blood
2020 | Journal article
EID:

2-s2.0-85085630385

Part of ISSN: 15280020 00064971
Contributors: Escamilla-Rivera, V.; Liu, J.; Gibb, D.R.; Santhanakrishnan, M.; Liu, D.; Forsmo, J.E.; Eisenbarth, S.C.; Foxman, E.F.; Stowell, S.R.; Luckey, C.J. et al.
Source: Self-asserted source
Chance John Luckey via Scopus - Elsevier

Red blood cell alloimmunization is associated with lower expression of FcγR1 on monocyte subsets in patients with sickle cell disease

Transfusion
2019 | Journal article
EID:

2-s2.0-85070340173

Part of ISSN: 15372995 00411132
Contributors: Balbuena-Merle, R.; Curtis, S.A.; Devine, L.; Gibb, D.R.; Karafin, M.S.; Luckey, C.J.; Tormey, C.A.; Siddon, A.J.; Roberts, J.D.; Hendrickson, J.E.
Source: Self-asserted source
Chance John Luckey via Scopus - Elsevier

Interleukin-6 receptor-alpha signaling drives anti-RBC alloantibody production and t-follicular helper cell differentiation in a murine model of red blood cell alloimmunization

Haematologica
2016 | Journal article
EID:

2-s2.0-84994553265

Part of ISSN: 15928721 03906078
Contributors: Arneja, A.; Salazar, J.E.; Jiang, W.; Hendrickson, J.E.; Zimring, J.C.; Luckey, C.J.
Source: Self-asserted source
Chance John Luckey via Scopus - Elsevier

Genetic and epigenetic fine mapping of causal autoimmune disease variants

Nature
2015 | Journal article
EID:

2-s2.0-84923326765

Part of ISSN: 14764687 00280836
Contributors: Farh, K.K.-H.; Marson, A.; Zhu, J.; Kleinewietfeld, M.; Housley, W.J.; Beik, S.; Shoresh, N.; Whitton, H.; Ryan, R.J.H.; Shishkin, A.A. et al.
Source: Self-asserted source
Chance John Luckey via Scopus - Elsevier

Alternative splicing of MBD2 supports self-renewal in human pluripotent stem cells

Cell Stem Cell
2014 | Journal article
EID:

2-s2.0-84904044398

Part of ISSN: 18759777 19345909
Contributors: Lu, Y.; Loh, Y.-H.; Li, H.; Cesana, M.; Ficarro, S.B.; Parikh, J.R.; Salomonis, N.; Toh, C.-X.D.; Andreadis, S.T.; Luckey, C.J. et al.
Source: Self-asserted source
Chance John Luckey via Scopus - Elsevier

Blood and bombs: Blood use after the Boston Marathon bombing of April 15, 2013

Transfusion
2014 | Journal article
EID:

2-s2.0-84898645197

Part of ISSN: 15372995 00411132
Contributors: Quillen, K.; Luckey, C.J.
Source: Self-asserted source
Chance John Luckey via Scopus - Elsevier

A mouse model of hemolytic disease of the newborn

Blood
2013 | Journal article
EID:

2-s2.0-84886820938

Part of ISSN: 00064971 15280020
Contributors: Luckey, C.J.; Silberstein, L.E.
Source: Self-asserted source
Chance John Luckey via Scopus - Elsevier

Culture of mouse amniotic fluid-derived cells on irradiated STO feeders results in the generation of primitive endoderm cell lines capable of self-renewal in vitro

Cells Tissues Organs
2013 | Journal article
EID:

2-s2.0-84888231874

Part of ISSN: 14226405 14226421
Contributors: Babic, A.M.; Jang, S.; Nicolov, E.; Voicu, H.; Luckey, C.J.
Source: Self-asserted source
Chance John Luckey via Scopus - Elsevier

Genome-scale proteome quantification by DEEP SEQ mass spectrometry

Nature Communications
2013 | Journal article
EID:

2-s2.0-84893169526

Part of ISSN: 20411723
Contributors: Zhou, F.; Lu, Y.; Ficarro, S.B.; Adelmant, G.; Jiang, W.; Luckey, C.J.; Marto, J.A.
Source: Self-asserted source
Chance John Luckey via Scopus - Elsevier

C/EBPα and DEK coordinately regulate myeloid differentiation

Blood
2012 | Journal article
EID:

2-s2.0-84861494721

Part of ISSN: 00064971 15280020
Contributors: Koleva, R.I.; Ficarro, S.B.; Radomska, H.S.; Carrasco-Alfonso, M.J.; Alberta, J.A.; Webber, J.T.; Luckey, C.J.; Marcucci, G.; Tenen, D.G.; Marto, J.A.
Source: Self-asserted source
Chance John Luckey via Scopus - Elsevier

Stem-cell-like qualities of immune memory; CD4 <sup>+</sup> T cells join the party

Cell Stem Cell
2012 | Journal article
EID:

2-s2.0-84856689626

Part of ISSN: 18759777 19345909
Contributors: Luckey, C.J.; Weaver, C.T.
Source: Self-asserted source
Chance John Luckey via Scopus - Elsevier

Online nanoflow multidimensional fractionation for high efficiency phosphopeptide analysis

Molecular and Cellular Proteomics
2011 | Journal article
EID:

2-s2.0-80555134728

Part of ISSN: 15359476 15359484
Contributors: Ficarro, S.B.; Zhang, Y.; Carrasco-Alfonso, M.J.; Garg, B.; Adelmant, G.; Webber, J.T.; Luckey, C.J.; Marto, J.A.
Source: Self-asserted source
Chance John Luckey via Scopus - Elsevier

Understanding the first steps in embryonic stem cell exit from the pluripotent state

Transfusion
2011 | Journal article
EID:

2-s2.0-81055133463

Part of ISSN: 00411132 15372995
Contributors: Luckey, C.J.; Lu, Y.; Marto, J.A.
Source: Self-asserted source
Chance John Luckey via Scopus - Elsevier

A robust error model for iTRAQ quantification reveals divergent signaling between oncogenic FLT3 mutants in acute myeloid leukemia

Molecular and Cellular Proteomics
2010 | Journal article
EID:

2-s2.0-77951820417

Part of ISSN: 15359476
Contributors: Zhang, Y.; Askenazi, M.; Jiang, J.; Luckey, C.J.; Griffin, J.D.; Marto, J.A.
Source: Self-asserted source
Chance John Luckey via Scopus - Elsevier

Improved electrospray ionization efficiency compensates for diminished chromatographic resolution and enables proteomics analysis of tyrosine signaling in embryonic stem cells

Analytical Chemistry
2009 | Journal article
EID:

2-s2.0-66149091950

Part of ISSN: 00032700
Contributors: Ficarro, S.B.; Zhang, Y.; Lu, Y.; Moghimi, A.R.; Askenazi, M.; Hyatt, E.; Smith, E.D.; Boyer, L.; Schlaeger, T.M.; Luckey, C.J. et al.
Source: Self-asserted source
Chance John Luckey via Scopus - Elsevier

Memory T and memory B cells share a transcriptional program of self-renewal with long-term hematopoietic stem cells

Proceedings of the National Academy of Sciences of the United States of America
2006 | Journal article
EID:

2-s2.0-33644746220

Part of ISSN: 00278424
Contributors: Luckey, C.J.; Bhattacharya, D.; Goldrath, A.W.; Weissman, I.L.; Benoist, C.; Mathis, D.
Source: Self-asserted source
Chance John Luckey via Scopus - Elsevier

The molecular program induced in T cells undergoing homeostatic proliferation

Proceedings of the National Academy of Sciences of the United States of America
2004 | Journal article
EID:

2-s2.0-10044258463

Part of ISSN: 00278424
Contributors: Goldrath, A.W.; Luckey, C.J.; Park, R.; Benoist, C.; Mathis, D.
Source: Self-asserted source
Chance John Luckey via Scopus - Elsevier

Tapasin Is a Facilitator, Not an Editor, of Class I MHC Peptide Binding

Journal of Immunology
2003 | Journal article
EID:

2-s2.0-10744222173

Part of ISSN: 00221767
Contributors: Zarling, A.L.; Luckey, C.J.; Marto, J.A.; White, F.M.; Brame, C.J.; Evans, A.M.; Lehner, P.J.; Cresswell, P.; Shabanowitz, J.; Hunt, D.F. et al.
Source: Self-asserted source
Chance John Luckey via Scopus - Elsevier

Analysis of MHC class II antigen processing by quantitation of peptides that constitute nested sets

Journal of Immunology
2002 | Journal article
EID:

2-s2.0-0036839244

Part of ISSN: 00221767
Contributors: Lippolis, J.D.; White, F.M.; Marto, J.A.; Luckey, C.J.; Bullock, T.N.J.; Shabanowitz, J.; Hunt, D.F.; Engelhard, V.H.
Source: Self-asserted source
Chance John Luckey via Scopus - Elsevier

Differences in the expression of human class I MHC alleles and their associated peptides in the presence of proteasome inhibitors

Journal of Immunology
2001 | Journal article
EID:

2-s2.0-0035422908

Part of ISSN: 00221767
Contributors: Luckey, C.J.; Marto, J.A.; Partridge, M.; Hall, E.; White, F.M.; Lippolis, J.D.; Shabanowitz, J.; Hunt, D.F.; Engelhard, V.H.
Source: Self-asserted source
Chance John Luckey via Scopus - Elsevier

Identification and modulation of a naturally processed T cell epitope from the diabetes-associated autoantigen human glutamic acid decarboxylase 65 (hGAD65)

Proceedings of the National Academy of Sciences of the United States of America
2001 | Journal article
EID:

2-s2.0-0035852674

Part of ISSN: 00278424
Contributors: Nepom, G.T.; Lippolis, J.D.; White, F.M.; Masewicz, S.; Marto, J.A.; Herman, A.; Luckey, C.J.; Falk, B.; Shabanowitz, J.; Hunt, D.F. et al.
Source: Self-asserted source
Chance John Luckey via Scopus - Elsevier

Self-tolerance to the murine homologue of a tyrosinase-derived melanoma antigen: Implications for tumor immunotherapy

Journal of Experimental Medicine
2000 | Journal article
EID:

2-s2.0-0034599497

Part of ISSN: 00221007
Contributors: Colella, T.A.; Bullock, T.N.J.; Russell, L.B.; Mullins, D.W.; Overwijk, W.W.; Luckey, C.J.; Pierce, R.A.; Restifo, N.P.; Engelhard, V.H.
Source: Self-asserted source
Chance John Luckey via Scopus - Elsevier

Proteasomes can either generate or destroy MHC class I epitopes: Evidence for nonproteasomal epitope generation in the cytosol

Journal of Immunology
1998 | Journal article
EID:

2-s2.0-7144223429

Part of ISSN: 00221767
Contributors: Luckey, C.J.; King, G.M.; Marto, J.A.; Venketeswaran, S.; Maier, B.F.; Crotzer, V.L.; Colella, T.A.; Shabanowitz, J.; Hunt, D.F.; Engelhard, V.H.
Source: Self-asserted source
Chance John Luckey via Scopus - Elsevier

The class I antigen-processing pathway for the membrane protein tyrosinase involves translation in the endoplasmic reticulum and processing in the cytosol

Journal of Experimental Medicine
1998 | Journal article
EID:

2-s2.0-0031973735

Part of ISSN: 00221007
Contributors: Mosse, C.A.; Meadows, L.; Luckey, C.J.; Kittlesen, D.J.; Huczko, E.L.; Slingluff Jr., C.L.; Shabanowitz, J.; Hunt, D.F.; Engelhard, V.H.
Source: Self-asserted source
Chance John Luckey via Scopus - Elsevier

Three peroxisome protein packaging pathways suggested by selective permeabilization of yeast mutants defective in peroxisome biogenesis

Molecular Biology of the Cell
1993 | Journal article
EID:

2-s2.0-0027731109

Part of ISSN: 10591524
Contributors: Jing Wei Zhang; Luckey, C.; Lazarow, P.B.
Source: Self-asserted source
Chance John Luckey via Scopus - Elsevier

Peer review (1 review for 1 publication/grant)

Review activity for Bone marrow transplantation (1)