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European Molecular Biology Laboratory: Heidelberg, Baden-Württemberg, DE

(Genome Biology)
Employment
Source: Self-asserted source
Athanasios Typas

Works (50 of 79)

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LD-transpeptidation is crucial for fitness and polar growth in Agrobacterium tumefaciens

PLOS Genetics
2024-10-21 | Journal article
Contributors: Alena Aliashkevich; Jue D. Wang; Thomas Guest; Laura Alvarez; Michael C. Gilmore; Daniel Rea; Jennifer Amstutz; André Mateus; Bastian Schiffthaler; Iñigo Ruiz et al.
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Crossref

TAC–TIC, a high-throughput genetics method to identify triggers or blockers of bacterial toxin–antitoxin systems

Nature Protocols
2024-08 | Journal article
Contributors: Jacob Bobonis; Alessio Ling Jie Yang; Carlos Geert Pieter Voogdt; Athanasios Typas
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Crossref

Bactericidal effect of tetracycline in E. coli strain ED1a may be associated with ribosome dysfunction

Nature Communications
2024-06-05 | Journal article
Contributors: Iskander Khusainov; Natalie Romanov; Camille Goemans; Beata Turoňová; Christian E. Zimmerli; Sonja Welsch; Julian D. Langer; Athanasios Typas; Martin Beck
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Crossref

High-throughput anaerobic screening for identifying compounds acting against gut bacteria in monocultures or communities

Nature Protocols
2024-03 | Journal article
Contributors: Patrick Müller; Jacobo de la Cuesta-Zuluaga; Michael Kuhn; Maral Baghai Arassi; Tim Treis; Sonja Blasche; Michael Zimmermann; Peer Bork; Kiran Raosaheb Patil; Athanasios Typas et al.
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Crossref

Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome

2023-09-13 | Preprint
Contributors: Clément M Potel; Mira Lea Burtscher; Martin Garrido-Rodriguez; Amber Brauer-Nikonow; Isabelle Becher; Athanasios Typas; Michael Zimmermann; Mikhail M Savitski
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Crossref

A pathogen-specific isotope tracing approach reveals metabolic activities and fluxes of intracellular Salmonella

PLOS Biology
2023-08-18 | Journal article
Contributors: Karin Mitosch; Sebastian E. Winter; Martin Beyß; Prasad Phapale; Bernhard Drotleff; Katharina Nöh; Theodore Alexandrov; Kiran R. Patil; Athanasios Typas
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Crossref

The killing of human gut commensalE. coliED1a by tetracycline is associated with severe ribosome dysfunction

2023-07-06 | Preprint
Contributors: Iskander Khusainov; Natalie Romanov; Camille Goemans; Beata Turoňová; Christian E. Zimmerli; Sonja Welsch; Julian D. Langer; Athanasios Typas; Martin Beck
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Crossref

d-amino acids signal a stress-dependent run-away response in Vibrio cholerae

Nature Microbiology
2023-06-26 | Journal article
Contributors: Oihane Irazoki; Josy ter Beek; Laura Alvarez; André Mateus; Remy Colin; Athanasios Typas; Mikhail M. Savitski; Victor Sourjik; Ronnie P.-A. Berntsson; Felipe Cava
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Crossref

Early midcell localization of Escherichia coli PBP4 supports the function of peptidoglycan amidases

PLOS Genetics
2022-05-23 | Journal article
Contributors: Jolanda Verheul; Petra Anne Levin; Adam Lodge; Hamish C. L. Yau; Xiaolong Liu; Gabriela Boelter; Xinwei Liu; Alexandra S. Solovyova; Athanasios Typas; Manuel Banzhaf et al.
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Crossref

Bioactivity assessment of natural compounds using machine learning models trained on target similarity between drugs

PLOS Computational Biology
2022-04-25 | Journal article
Contributors: Vinita Periwal; Costas D. Maranas; Stefan Bassler; Sergej Andrejev; Natalia Gabrielli; Kaustubh Raosaheb Patil; Athanasios Typas; Kiran Raosaheb Patil
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Crossref

2FAST2Q: A general-purpose sequence search and counting program for FASTQ files

2021-12-18 | Preprint
Contributors: Afonso M. Bravo; Athanasios Typas; Jan-Willem Veening
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Crossref

High-throughput functional characterization of protein phosphorylation sites in yeast.

Nature biotechnology
2021-10-18 | Journal article
Source: Self-asserted source
Athanasios Typas

Unravelling the collateral damage of antibiotics on gut bacteria.

Nature
2021-10-13 | Journal article
Source: Self-asserted source
Athanasios Typas

Bioaccumulation of therapeutic drugs by human gut bacteria.

Nature
2021-09-08 | Journal article
Source: Self-asserted source
Athanasios Typas

Transcriptional and Post-Transcriptional Polar Effects in Bacterial Gene Deletion Libraries.

mSystems
2021-09-07 | Journal article
Source: Self-asserted source
Athanasios Typas

Impact of phosphorylation on thermal stability of proteins

Nature Methods
2021-07-17 | Journal article
Contributors: Clément M. Potel; Nils Kurzawa; Isabelle Becher; Athanasios Typas; André Mateus; Mikhail M. Savitski
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Crossref

Global mapping of Salmonella enterica-host protein-protein interactions during infection.

Cell host & microbe
2021-07-07 | Journal article
Source: Self-asserted source
Athanasios Typas

Towards a mechanistic understanding of reciprocal drug–microbiome interactions

Molecular Systems Biology
2021-03 | Journal article
Contributors: Michael Zimmermann; Kiran Raosaheb Patil; Athanasios Typas; Lisa Maier
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Crossref

SARS-CoV-2 infection remodels the host protein thermal stability landscape.

Molecular systems biology
2021-02-01 | Journal article
Source: Self-asserted source
Athanasios Typas

The functional proteome landscape of Escherichia coli

Nature
2020-12-17 | Journal article
Contributors: André Mateus; Johannes Hevler; Jacob Bobonis; Nils Kurzawa; Malay Shah; Karin Mitosch; Camille V. Goemans; Dominic Helm; Frank Stein; Athanasios Typas et al.
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Crossref

Bioactivity assessment of natural compounds using machine learning models based on drug target similarity

[]
2020-11-08 | Preprint
Source: Self-asserted source
Athanasios Typas

Midcell localization of PBP4 of Escherichia coli modulates the timing of divisome assembly

[]
2020-07-31 | Preprint
Source: Self-asserted source
Athanasios Typas

Bacterial retrons encode tripartite toxin/antitoxin systems

[]
2020-06-22 | Preprint
Source: Self-asserted source
Athanasios Typas

Phage proteins block and trigger retron toxin/antitoxin systems

[]
2020-06-22 | Preprint
Source: Self-asserted source
Athanasios Typas
grade
Preferred source (of 2)‎

Spatiotemporal proteomics uncovers cathepsin-dependent macrophage cell death during Salmonella infection.

Nature microbiology
2020-06-08 | Journal article
Source: Self-asserted source
Athanasios Typas

A Dual-Mechanism Antibiotic Kills Gram-Negative Bacteria and Avoids Drug Resistance.

Cell
2020-06-03 | Journal article
Source: Self-asserted source
Athanasios Typas

Thermal proteome profiling for interrogating protein interactions

Molecular Systems Biology
2020-03 | Journal article
Contributors: André Mateus; Nils Kurzawa; Isabelle Becher; Sindhuja Sridharan; Dominic Helm; Frank Stein; Athanasios Typas; Mikhail M Savitski
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Crossref

A dual-mechanism antibiotic targets Gram-negative bacteria and avoids drug resistance

2020-03-13 | Preprint
Contributors: James K. Martin; Maxwell Z. Wilson; Gabriel M. Moore; Joseph P. Sheehan; André Mateus; Sophia Hsin-Jung Li; Benjamin P. Bratton; Hahn Kim; Joshua D. Rabinowitz; Athanasios Typas et al.
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Crossref

Proton Motive Force Disruptors Block Bacterial Competence and Horizontal Gene Transfer.

Cell host & microbe
2020-03-03 | Journal article
Source: Self-asserted source
Athanasios Typas

Systematic Localization of Escherichia coli Membrane Proteins.

mSystems
2020-03-03 | Journal article
Source: Self-asserted source
Athanasios Typas

Outer membrane lipoprotein NlpI scaffolds peptidoglycan hydrolases within multi-enzyme complexes in Escherichia coli.

The EMBO journal
2020-02-03 | Journal article
Source: Self-asserted source
Athanasios Typas

Impact of phosphorylation on thermal stability of proteins

2020-01-14 | Preprint
Contributors: Clément M. Potel; Nils Kurzawa; Isabelle Becher; Athanasios Typas; André Mateus; Mikhail M. Savitski
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Crossref

The impact of the genetic background on gene deletion phenotypes in Saccharomyces cerevisiae

Molecular Systems Biology
2019-12 | Journal article
Contributors: Marco Galardini; Bede P Busby; Cristina Vieitez; Alistair S Dunham; Athanasios Typas; Pedro Beltrao
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Crossref

The first wide-scale drug repurposing screen using the Prestwick Chemical Library (1200 bioactive molecules) against Neisseria gonorrhoeae identifies high in vitro activity of auranofin and many additional drugs.

APMIS : acta pathologica, microbiologica, et immunologica Scandinavica
2019-12-07 | Journal article
Source: Self-asserted source
Athanasios Typas

Systematic localization of Gram-negative bacterial membrane proteins

2019-11-25 | Other
Contributors: Anna Sueki; Frank Stein; Mikhail Savitski; Joel Selkrig; Athanasios Typas
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Crossref

A new antibiotic selectively kills Gram-negative pathogens.

Nature
2019-11-20 | Journal article
Source: Self-asserted source
Athanasios Typas

Escherichia coli limits Salmonella Typhimurium infections after diet shifts and fat-mediated microbiota perturbation in mice.

Nature microbiology
2019-10-07 | Journal article
Source: Self-asserted source
Athanasios Typas

A resource of variant effect predictions of single nucleotide variants in model organisms

Molecular Systems Biology
2018-12 | Journal article
Contributors: Omar Wagih; Marco Galardini; Bede P Busby; Danish Memon; Athanasios Typas; Pedro Beltrao
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Crossref

Recovery of gut microbiota of healthy adults following antibiotic exposure.

Nature microbiology
2018-10-22 | Journal article
Source: Self-asserted source
Athanasios Typas

Editorial overview

Current Opinion in Systems Biology
2018-08 | Journal article
Contributors: Mikhail Savitski; Athanasios Typas
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Crossref

Thermal proteome profiling in bacteria: probing protein state in vivo

Molecular Systems Biology
2018-07 | Journal article
Contributors: André Mateus; Jacob Bobonis; Nils Kurzawa; Frank Stein; Dominic Helm; Johannes Hevler; Athanasios Typas; Mikhail M Savitski
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Crossref

Species-specific activity of antibacterial drug combinations.

Nature
2018-07-04 | Journal article
Source: Self-asserted source
Athanasios Typas

Pervasive Protein Thermal Stability Variation during the Cell Cycle.

Cell
2018-04-26 | Journal article
Source: Self-asserted source
Athanasios Typas

Extensive impact of non-antibiotic drugs on human gut bacteria.

Nature
2018-03-19 | Journal article
Source: Self-asserted source
Athanasios Typas

Nutritional preferences of human gut bacteria reveal their metabolic idiosyncrasies.

Nature microbiology
2018-03-19 | Journal article
Source: Self-asserted source
Athanasios Typas

Salt-responsive gut commensal modulates T<sub>H</sub>17 axis and disease.

Nature
2017-11-15 | Journal article
Source: Self-asserted source
Athanasios Typas

Emerging and evolving concepts in gene essentiality.

Nature reviews. Genetics
2017-10-16 | Journal article
Source: Self-asserted source
Athanasios Typas

Systematically investigating the impact of medication on the gut microbiome.

Current opinion in microbiology
2017-10-01 | Journal article
Source: Self-asserted source
Athanasios Typas

Yeast Creates a Niche for Symbiotic Lactic Acid Bacteria through Nitrogen Overflow.

Cell systems
2017-09-27 | Journal article
Source: Self-asserted source
Athanasios Typas

Chemical genetics in drug discovery.

Current opinion in systems biology
2017-08-01 | Journal article
Source: Self-asserted source
Athanasios Typas
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Peer review (14 reviews for 8 publications/grants)

Review activity for Current opinion in microbiology. (1)
Review activity for Nature (3)
Review activity for Nature communications (2)
Review activity for Nature genetics. (1)
Review activity for Nature microbiology. (3)
Review activity for Nature reviews. (2)
Review activity for PLoS biology. (1)
Review activity for Trends in endocrinology and metabolism (1)