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Works (7)

Pathogenic effects of Leu200Pro and Arg387His VRK1 protein variants on phosphorylation targets and H4K16 acetylation in distal hereditary motor neuropathy

Journal of Molecular Medicine
2024-06 | Journal article
DOI: 10.1007/s00109-024-02442-8
Contributors: Aurora Campos-Díaz; Patricia Morejón-García; Eva Monte-Serrano; David Ros-Pardo; Iñigo Marcos-Alcalde; Paulino Gómez-Puertas; Pedro A. Lazo
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VRK1 Regulates Sensitivity to Oxidative Stress by Altering Histone Epigenetic Modifications and the Nuclear Phosphoproteome in Tumor Cells

International Journal of Molecular Sciences
2024-04-30 | Journal article
DOI: 10.3390/ijms25094874
Contributors: Elena Navarro-Carrasco; Eva Monte-Serrano; Aurora Campos-Díaz; Frank Rolfs; Richard de Goeij-de Haas; Thang V. Pham; Sander R. Piersma; Paula González-Alonso; Connie R. Jiménez; Pedro A. Lazo
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Loss of VRK1 alters the nuclear phosphoproteome in the DNA damage response to doxorubicin

Chemico-Biological Interactions
2024-03 | Journal article
DOI: 10.1016/j.cbi.2024.110908
Contributors: Elena Navarro-Carrasco; Aurora Campos-Díaz; Eva Monte-Serrano; Frank Rolfs; Richard de Goeij-de Haas; Thang V. Pham; Sander R. Piersma; Connie R. Jiménez; Pedro A. Lazo
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The pattern of histone H3 epigenetic posttranslational modifications is regulated by the VRK1 chromatin kinase

Epigenetics & Chromatin
2023-05-13 | Journal article
DOI: 10.1186/s13072-023-00494-7
Contributors: Eva Monte-Serrano; Patricia Morejón-García; Ignacio Campillo-Marcos; Aurora Campos-Díaz; Elena Navarro-Carrasco; Pedro A. Lazo
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VRK1 Kinase Activity Modulating Histone H4K16 Acetylation Inhibited by SIRT2 and VRK-IN-1

International Journal of Molecular Sciences
2023-03-03 | Journal article
DOI: 10.3390/ijms24054912
Contributors: Eva Monte-Serrano; Pedro A. Lazo
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The VRK1 chromatin kinase regulates the acetyltransferase activity of Tip60/KAT5 by sequential phosphorylations in response to DNA damage

Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms
2022-11 | Journal article
DOI: 10.1016/j.bbagrm.2022.194887
Contributors: Raúl García-González; Eva Monte-Serrano; Patricia Morejón-García; Elena Navarro-Carrasco; Pedro A. Lazo
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Lysine Methyltransferase Inhibitors Impair H4K20me2 and 53BP1 Foci in Response to DNA Damage in Sarcomas, a Synthetic Lethality Strategy

Frontiers in Cell and Developmental Biology
2021-09-03 | Journal article
DOI: 10.3389/fcell.2021.715126
Part of ISSN: 2296-634X
Contributors: Ignacio Campillo-Marcos; Eva Monte-Serrano; Elena Navarro-Carrasco; Raúl García-González; Pedro A. Lazo
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Eva Monte Serrano
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