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Activities

Employment (1)

Wenzhou Medical University: Wenzhou, Zhejiang, CN

2018-08-01 to present (School of Biomedical Engineering)
Employment
Source: Self-asserted source
Jie Sun

Education and qualifications (2)

Harbin Medical University: Harbin, Heilongjiang, CN

2009-09-01 to 2012-07-01 | PhD (College of Bioinformatics Science and Technology)
Education
Source: Self-asserted source
Jie Sun

Jilin University: Changchun, CN

2007-09-01 to 2009-07-01 | M.S. (School of Mathematics)
Education
Source: Self-asserted source
Jie Sun

Funding (3)

Research on the systematic identification of immune-related lncRNAs and its regulatory characteristics in ovarian cancer

2020-01 to 2023-12 | Grant
National Natural Science Foundation of China (wenzhou, CN)
Source: Self-asserted source
Jie Sun

Research on the identification and regulatory characteristics of lncRNAs for malignant tumor based on expression profiles and molecular networks

2017-01 to 2019-12 | Grant
National Natural Science Foundation of China (wenzhou, CN)
Source: Self-asserted source
Jie Sun

Research on network reconstruction and regulatory pattern of lncRNAs in complex diseases

2014-01 to 2016-12 | Grant
China Postdoctoral Science Foundation (wenzhou, CN)
Source: Self-asserted source
Jie Sun

Works (50)

Leveraging pharmacovigilance data to predict population-scale toxicity profiles of checkpoint inhibitor immunotherapy

Nature Computational Science
2024-12-23 | Journal article
Contributors: Dongxue Yan; Siqi Bao; Zicheng Zhang; Jie Sun; Meng Zhou
Source: check_circle
Crossref

Single-cell and bulk transcriptome analysis reveals tumor cell heterogeneity and underlying molecular program in uveal melanoma

Journal of Translational Medicine
2024-11-12 | Journal article
Contributors: Ke Li; Jingzhe Huang; Ying Tan; Jie Sun; Meng Zhou
Source: check_circle
Crossref

Integrated immuno-transcriptomic analysis of ovarian cancer identifies a four-chemokine-dominated subtype with antitumor immune-active phenotype and favorable prognosis

British Journal of Cancer
2024-10-05 | Journal article
Contributors: Lili Zhuo; Fanling Meng; Kaidi Sun; Meng Zhou; Jie Sun
Source: check_circle
Crossref

Single-cell characterization of macrophages in uveal melanoma uncovers transcriptionally heterogeneous subsets conferring poor prognosis and aggressive behavior

Experimental & Molecular Medicine
2023-11-01 | Journal article
Contributors: Ke Li; Lanfang Sun; Yanan Wang; Yixin Cen; Jingting Zhao; Qianling Liao; Wencan Wu; Jie Sun; Meng Zhou
Source: check_circle
Crossref

Noninvasive early differential diagnosis and progression monitoring of ovarian cancer using the copy number alterations of plasma cell-free DNA

Translational Research
2023-07 | Journal article
Contributors: Lu Chen; Rong Ma; Chang Luo; Qin Xie; Xin Ning; Kaidi Sun; Fanling Meng; Meng Zhou; Jie Sun
Source: check_circle
Crossref

Deep learning identifies a T-cell exhaustion-dependent transcriptional signature for predicting clinical outcomes and response to immune checkpoint blockade

Oncogenesis
2023-07-11 | Journal article
Contributors: Zicheng Zhang; Hongyan Chen; Dongxue Yan; Lu Chen; Jie Sun; Meng Zhou
Source: check_circle
Crossref

The transcriptional landscape and diagnostic potential of long non-coding RNAs in esophageal squamous cell carcinoma

Nature Communications
2023-06-26 | Journal article
Contributors: Meng Zhou; Siqi Bao; Tongyang Gong; Qiang Wang; Jie Sun; Jiaqi Li; Minyi Lu; Wanyuan Sun; Jianzhong Su; Hongyan Chen et al.
Source: check_circle
Crossref

Upregulation of SLC12A3 and SLC12A9 Mediated by the HCP5/miR-140-5p Axis Confers Aggressiveness and Unfavorable Prognosis in Uveal Melanoma

Laboratory Investigation
2023-03 | Journal article
Contributors: Congcong Yan; Xiaojuan Hu; Xiaoyan Liu; Jingting Zhao; Zhenmin Le; Jiayao Feng; Meng Zhou; Xiaoyin Ma; Qingxiang Zheng; Jie Sun
Source: check_circle
Crossref

Efficacy of Different Number of XELOX or SOX Chemotherapy Cycles After D2 Resection for Stage III Gastric Cancer

Journal of Gastric Cancer
2022 | Journal article
Contributors: Yuanyuan Yu; Zicheng Zhang; Qianhao Meng; Ke Wang; Qingwei Li; Yue Ma; Yuanfei Yao; Jie Sun; Guangyu Wang
Source: check_circle
Crossref

Immuno-genomic characterisation of high-grade serous ovarian cancer reveals immune evasion mechanisms and identifies an immunological subtype with a favourable prognosis and improved therapeutic efficacy

British Journal of Cancer
2022-06-01 | Journal article
Contributors: Jie Sun; Congcong Yan; Dandan Xu; Zicheng Zhang; Ke Li; Xiaobo Li; Meng Zhou; Dapeng Hao
Source: check_circle
Crossref

iUMRG: multi-layered network-guided propagation modeling for the inference of susceptibility genes and potential drugs against uveal melanoma

npj Systems Biology and Applications
2022-05-24 | Journal article
Contributors: Yueping Ren; Congcong Yan; Lili Wu; Jingting Zhao; Mingwei Chen; Meng Zhou; Xiaoyan Wang; Tonghua Liu; Quanyong Yi; Jie Sun
Source: check_circle
Crossref

The pan-cancer landscape of crosstalk between epithelial-mesenchymal transition and immune evasion relevant to prognosis and immunotherapy response

npj Precision Oncology
2021-06-22 | Journal article
Contributors: Guangyu Wang; Dandan Xu; Zicheng Zhang; Xinhui Li; Jiaqi Shi; Jie Sun; Huan-Zhong Liu; Xiaobo Li; Meng Zhou; Tongsen Zheng
Source: check_circle
Crossref

Pan-cancer characterization of lncRNA modifiers of immune microenvironment reveals clinically distinct de novo tumor subtypes

npj Genomic Medicine
2021-06-17 | Journal article
Contributors: Zicheng Zhang; Congcong Yan; Ke Li; Siqi Bao; Lei Li; Lu Chen; Jingting Zhao; Jie Sun; Meng Zhou
Source: check_circle
Crossref

Computational recognition of lncRNA signature of tumor-infiltrating B lymphocytes with potential implications in prognosis and immunotherapy of bladder cancer

Briefings In Bioinformatics
2020 | Journal article
Part of ISSN: 1467-5463
Part of ISSN: 1477-4054
Source: Self-asserted source
Jie Sun

Identification of tumor immune infiltration-associated lncRNAs for improving prognosis and immunotherapy response of patients with non-small cell lung cancer

Journal for ImmunoTherapy of Cancer
2020-02 | Journal article
Part of ISSN: 2051-1426
Source: Self-asserted source
Jie Sun

Computational identification of mutator-derived lncRNA signatures of genome instability for improving the clinical outcome of cancers: a case study in breast cancer

Briefings in Bioinformatics
2019-10-28 | Journal article
Part of ISSN: 1467-5463
Part of ISSN: 1477-4054
Source: Self-asserted source
Jie Sun

Large-scale integrated analysis of ovarian cancer tumors and cell lines identifies an individualized gene expression signature for predicting response to platinum-based chemotherapy

Cell Death & Disease
2019-09 | Journal article
Part of ISSN: 2041-4889
Source: Self-asserted source
Jie Sun

Systematic Characterization of Circular RNA-Associated CeRNA Network Identified Novel circRNA Biomarkers in Alzheimer's Disease

Frontiers in Bioengineering and Biotechnology
2019-09-11 | Journal article
Part of ISSN: 2296-4185
Source: Self-asserted source
Jie Sun

Integrative analysis from multi‐centre studies identifies a function‐derived personalized multi‐gene signature of outcome in colorectal cancer

Journal of Cellular and Molecular Medicine
2019-08 | Journal article
Part of ISSN: 1582-1838
Part of ISSN: 1582-4934
Source: Self-asserted source
Jie Sun

Analysis of long noncoding RNAs highlights region-specific altered expression patterns and diagnostic roles in Alzheimer’s disease

Briefings in Bioinformatics
2019-03-25 | Journal article
Part of ISSN: 1477-4054
Source: Self-asserted source
Jie Sun
grade
Preferred source (of 2)‎

Recurrence-Associated Long Non-coding RNA Signature for Determining the Risk of Recurrence in Patients with Colon Cancer.

Molecular therapy. Nucleic acids
2018-06 | Journal article
Contributors: Zhou M; Hu L; Zhang Z; Wu N; Sun J; Su J
Source: Self-asserted source
Jie Sun via Europe PubMed Central

A novel lncRNA-focus expression signature for survival prediction in endometrial carcinoma.

BMC cancer
2018-01 | Journal article
Contributors: Zhou M; Zhang Z; Zhao H; Bao S; Sun J
Source: Self-asserted source
Jie Sun via Europe PubMed Central

InfAcrOnt: calculating cross-ontology term similarities using information flow by a random walk.

BMC genomics
2018-01 | Journal article
Contributors: Cheng L; Jiang Y; Ju H; Sun J; Peng J; Zhou M; Hu Y
Source: Self-asserted source
Jie Sun via Europe PubMed Central

An Immune-Related Six-lncRNA Signature to Improve Prognosis Prediction of Glioblastoma Multiforme.

Molecular neurobiology
2017-05 | Journal article
Contributors: Zhou M; Zhang Z; Zhao H; Bao S; Cheng L; Sun J
Source: Self-asserted source
Jie Sun via Europe PubMed Central

Discovery and validation of immune-associated long non-coding RNA biomarkers associated with clinically molecular subtype and prognosis in diffuse large B cell lymphoma.

Molecular cancer
2017-01 | Journal article
Contributors: Zhou M; Zhao H; Xu W; Bao S; Cheng L; Sun J
Source: Self-asserted source
Jie Sun via Europe PubMed Central

OAHG: an integrated resource for annotating human genes with multi-level ontologies.

Scientific reports
2016-10 | Journal article
Contributors: Cheng L; Sun J; Xu W; Dong L; Hu Y; Zhou M
Source: Self-asserted source
Jie Sun via Europe PubMed Central

Construction and analysis of dysregulated lncRNA-associated ceRNA network identified novel lncRNA biomarkers for early diagnosis of human pancreatic cancer.

Oncotarget
2016-08 | Journal article
Contributors: Zhou M; Diao Z; Yue X; Chen Y; Zhao H; Cheng L; Sun J
Source: Self-asserted source
Jie Sun via Europe PubMed Central

Discovery of potential prognostic long non-coding RNA biomarkers for predicting the risk of tumor recurrence of breast cancer patients.

Scientific reports
2016-08 | Journal article
Contributors: Zhou M; Zhong L; Xu W; Sun Y; Zhang Z; Zhao H; Yang L; Sun J
Source: Self-asserted source
Jie Sun via Europe PubMed Central

DisSim: an online system for exploring significant similar diseases and exhibiting potential therapeutic drugs.

Scientific reports
2016-07 | Journal article
Contributors: Cheng L; Jiang Y; Wang Z; Shi H; Sun J; Yang H; Zhang S; Hu Y; Zhou M
Source: Self-asserted source
Jie Sun via Europe PubMed Central

IntNetLncSim: an integrative network analysis method to infer human lncRNA functional similarity.

Oncotarget
2016-07 | Journal article
Contributors: Cheng L; Shi H; Wang Z; Hu Y; Yang H; Zhou C; Sun J; Zhou M
Source: Self-asserted source
Jie Sun via Europe PubMed Central

A potential panel of six-long non-coding RNA signature to improve survival prediction of diffuse large-B-cell lymphoma.

Scientific reports
2016-06 | Journal article
Contributors: Sun J; Cheng L; Shi H; Zhang Z; Zhao H; Wang Z; Zhou M
Source: Self-asserted source
Jie Sun via Europe PubMed Central

Comprehensive analysis of lncRNA expression profiles reveals a novel lncRNA signature to discriminate nonequivalent outcomes in patients with ovarian cancer.

Oncotarget
2016-05 | Journal article
Contributors: Zhou M; Sun Y; Sun Y; Xu W; Zhang Z; Zhao H; Zhong Z; Sun J
Source: Self-asserted source
Jie Sun via Europe PubMed Central

Relapse-related long non-coding RNA signature to improve prognosis prediction of lung adenocarcinoma.

Oncotarget
2016-05 | Journal article
Contributors: Zhou M; Xu W; Yue X; Zhao H; Wang Z; Shi H; Cheng L; Sun J
Source: Self-asserted source
Jie Sun via Europe PubMed Central

Characterization of long non-coding RNA-associated ceRNA network to reveal potential prognostic lncRNA biomarkers in human ovarian cancer.

Oncotarget
2016-03 | Journal article
Contributors: Zhou M; Wang X; Shi H; Cheng L; Wang Z; Zhao H; Yang L; Sun J
Source: Self-asserted source
Jie Sun via Europe PubMed Central

Integration of Multiple Genomic and Phenotype Data to Infer Novel miRNA-Disease Associations.

PloS one
2016-02 | Journal article
Contributors: Shi H; Zhang G; Zhou M; Cheng L; Yang H; Wang J; Sun J; Wang Z
Source: Self-asserted source
Jie Sun via Europe PubMed Central

A potential prognostic long non-coding RNA signature to predict metastasis-free survival of breast cancer patients.

Scientific reports
2015-11 | Journal article
Contributors: Sun J; Chen X; Wang Z; Guo M; Shi H; Wang X; Cheng L; Zhou M
Source: Self-asserted source
Jie Sun via Europe PubMed Central

Identification and validation of potential prognostic lncRNA biomarkers for predicting survival in patients with multiple myeloma.

Journal of experimental & clinical cancer research : CR
2015-09 | Journal article
Contributors: Zhou M; Zhao H; Wang Z; Cheng L; Yang L; Shi H; Yang H; Sun J
Source: Self-asserted source
Jie Sun via Europe PubMed Central

Identification of Aberrant Chromosomal Regions in Human Breast Cancer Using Gene Expression Data and Related Gene Information.

Medical science monitor : international medical journal of experimental and clinical research
2015-08 | Journal article
Contributors: Wang HJ; Zhou M; Jia L; Sun J; Shi HB; Liu SL; Wang ZZ
Source: Self-asserted source
Jie Sun via Europe PubMed Central

A potential signature of eight long non-coding RNAs predicts survival in patients with non-small cell lung cancer.

Journal of translational medicine
2015-07 | Journal article
Contributors: Zhou M; Guo M; He D; Wang X; Cui Y; Yang H; Hao D; Sun J
Source: Self-asserted source
Jie Sun via Europe PubMed Central

Inferring novel lncRNA-disease associations based on a random walk model of a lncRNA functional similarity network.

Molecular bioSystems
2014-08 | Journal article
Contributors: Sun J; Shi H; Wang Z; Zhang C; Liu L; Wang L; He W; Hao D; Liu S; Zhou M
Source: Self-asserted source
Jie Sun via Europe PubMed Central

Inferring potential microRNA-microRNA associations based on targeting propensity and connectivity in the context of protein interaction network.

PloS one
2013-07 | Journal article
Contributors: Sun J; Zhou M; Yang H; Deng J; Wang L; Wang Q
Source: Self-asserted source
Jie Sun via Europe PubMed Central

Systematic analysis of genomic organization and structure of long non-coding RNAs in the human genome.

FEBS letters
2013-02 | Journal article
Contributors: Sun J; Zhou M; Mao ZT; Hao DP; Wang ZZ; Li CX
Source: Self-asserted source
Jie Sun via Europe PubMed Central

Comparative genomic analysis reveals evolutionary characteristics and patterns of microRNA clusters in vertebrates.

Gene
2012-10 | Journal article
Contributors: Sun J; Gao B; Zhou M; Wang ZZ; Zhang F; Deng JE; Li X
Source: Self-asserted source
Jie Sun via Europe PubMed Central

Characterization and evolution of microRNA genes derived from repetitive elements and duplication events in plants.

PloS one
2012-04 | Journal article
Contributors: Sun J; Zhou M; Mao Z; Li C
Source: Self-asserted source
Jie Sun via Europe PubMed Central

Systematic analysis of genomic organization and heterogeneities of miRNA cluster in vertebrates.

Molecular biology reports
2011-12 | Journal article
Contributors: Sun J; Liu HP; Deng JE; Zhou M
Source: Self-asserted source
Jie Sun via Europe PubMed Central

Prioritizing human cancer microRNAs based on genes' functional consistency between microRNA and cancer.

Nucleic acids research
2011-10 | Journal article
Contributors: Li X; Wang Q; Zheng Y; Lv S; Ning S; Sun J; Huang T; Zheng Q; Ren H; Xu J et al.
Source: Self-asserted source
Jie Sun via Europe PubMed Central

A novel network-based method for measuring the functional relationship between gene sets.

Bioinformatics (Oxford, England)
2011-03 | Journal article
Contributors: Wang Q; Sun J; Zhou M; Yang H; Li Y; Li X; Lv S; Li X; Li Y
Source: Self-asserted source
Jie Sun via Europe PubMed Central

Genome-wide analysis of clustering patterns and flanking characteristics for plant microRNA genes.

The FEBS journal
2011-02 | Journal article
Contributors: Zhou M; Sun J; Wang QH; Song LQ; Zhao G; Wang HZ; Yang HX; Li X
Source: Self-asserted source
Jie Sun via Europe PubMed Central

Systematic analysis of human microRNA divergence based on evolutionary emergence.

FEBS letters
2010-12 | Journal article
Contributors: Wang QH; Zhou M; Sun J; Ning SW; Li Y; Chen L; Zheng Y; Li X; Lv SL; Li X
Source: Self-asserted source
Jie Sun via Europe PubMed Central

In silico detection and characteristics of novel microRNA genes in the Equus caballus genome using an integrated ab initio and comparative genomic approach.

Genomics
2009-05 | Journal article
Contributors: Zhou M; Wang Q; Sun J; Li X; Xu L; Yang H; Shi H; Ning S; Chen L; Li Y et al.
Source: Self-asserted source
Jie Sun via Europe PubMed Central