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Scopus Author ID: 6507913358

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Employment (6)

The Francis Crick Institute: London, GB

2024-01-17 to present
Employment
Source: Self-asserted source
Irene Miguel-Aliaga

Imperial College London: London, London, GB

2012-11-01 to present | Professor of Genetics and Phsyiology and Section Chair (Institute of Clinical Sciences)
Employment
Source: Self-asserted source
Irene Miguel-Aliaga

University of Cambridge: Cambridge, Cambridgeshire, GB

2008-06-01 to 2012-10-12 | Wellcome Trust Research Career Development Fellow (Department of Zoology)
Employment
Source: Self-asserted source
Irene Miguel-Aliaga

National Institute for Medical Research: London, London, GB

2005-01-03 to 2008-05-30 | EU Marie Curie Postdoctoral Fellow
Employment
Source: Self-asserted source
Irene Miguel-Aliaga

Linkopings universitet Medicinska Fakulteten: Linkoping, SE

2004-05-01 to 2004-12-31 | Postdoctoral Fellow
Employment
Source: Self-asserted source
Irene Miguel-Aliaga

Harvard Medical School: Boston, MA, US

2001-03-01 to 2004-04-30 | Postdoctoral Fellow (Department of Neurobiology)
Employment
Source: Self-asserted source
Irene Miguel-Aliaga

Education and qualifications (2)

University of Oxford: Oxford, Oxfordshire, GB

1997-09-26 to 2001-03-01 (Human Anatomy and Genetics)
Qualification
Source: Self-asserted source
Irene Miguel-Aliaga

Universitat Autonoma de Barcelona: Barcelona, ES

1991-09-01 to 1997-06-30 | BSc Biochemistry (First-class Honours Degree)
Education
Source: Self-asserted source
Irene Miguel-Aliaga

Professional activities (11)

Medical Research Council: London, London, GB

2019-04-01 to present | Member of MRC Neurosciences & Mental Health Board
Service
Source: Self-asserted source
Irene Miguel-Aliaga

Imperial College London: London, London, GB

2017-07-09 to present | Member of Imperial College European Advisory Group.
Service
Source: Self-asserted source
Irene Miguel-Aliaga

Institut de Génomique Fonctionnelle de Lyon: Lyon, Rhône-Alpes, FR

2017-06-02 to present | Chair of Scientific Advisory Board
Service
Source: Self-asserted source
Irene Miguel-Aliaga

Imperial College London: London, London, GB

2016-12-01 to present | Member of Faculty of Medicine Imperial College Research Fellowships Panel.
Service
Source: Self-asserted source
Irene Miguel-Aliaga

MRC Clinical Sciences Centre: London, London, GB

2016-08-07 to present | Member of Athena Swan Opportunities Committee
Service
Source: Self-asserted source
Irene Miguel-Aliaga

Biotechnology and Biological Sciences Research Council: London, GB

2015-06-04 to present | Member of Pool of Experts
Service
Source: Self-asserted source
Irene Miguel-Aliaga

MRC Clinical Sciences Centre: London, London, GB

2015-05-03 to present | Member of MRC LMS Institute Planning and Operations Group
Service
Source: Self-asserted source
Irene Miguel-Aliaga

EMBO: Heidelberg, DE

2017-04-07 | Elected to EMBO as full member
Distinction
Source: Self-asserted source
Irene Miguel-Aliaga

EMBO: Heidelberg, DE

2012-01-01 to 2014-12-31 | Elected to EMBO YIP programme
Distinction
Source: Self-asserted source
Irene Miguel-Aliaga

Ministerio de Ciencia y Tecnología: Madrid, ES

1997-01-01 to 1997-12-30 | Best national academic record
Distinction
Source: Self-asserted source
Irene Miguel-Aliaga

Universitat Autonoma de Barcelona Facultat de Ciències Polítiques i de Sociologia: Bellaterra, Catalunya, ES

1997-01-01 to 1997-11-30 | Prize for the best academic record
Distinction
Source: Self-asserted source
Irene Miguel-Aliaga

Funding (7)

IntraGutSex; Sex differences in intestinal plasticity

2018-10 to 2023-09 | Grant
European Commission (Brussels, BE)
Source: Self-asserted source
Irene Miguel-Aliaga

A new vessel in the fleet: exploring how enteric tracheal plasticity drives metabolic adaptation in Drosophila

2016-01-01 to 2018-12-31 | Grant
Biotechnology and Biological Sciences Research Council (Swindon, GB)
URL: https://app.dimensions.ai/details/grant/grant.4575596
GRANT_NUMBER: BB/N000528/1
Source: Self-asserted source
Irene Miguel-Aliaga via DimensionsWizard

Brain-gut interactions in Drosophila melanogaster

2013-02-01 to 2018-01-31 | Grant
European Research Council (Brussels, BE)
URL: https://app.dimensions.ai/details/grant/grant.3800553
GRANT_NUMBER: 310411
Source: Self-asserted source
Irene Miguel-Aliaga via DimensionsWizard

Mechanisms of intestinal innervation and vascularization

2013-01-01 to 2015-06-29 | Grant
Biotechnology and Biological Sciences Research Council (Swindon, GB)
URL: https://app.dimensions.ai/details/grant/grant.2768913
GRANT_NUMBER: BB/J007110/1
Source: Self-asserted source
Irene Miguel-Aliaga via DimensionsWizard

Gut Signalling and Metabolism

2012-09-30 to present | Grant
Medical Research Council (London, GB)
URL: https://app.dimensions.ai/details/grant/grant.2772077
GRANT_NUMBER: MC_UP_1102/3
Source: Self-asserted source
Irene Miguel-Aliaga via DimensionsWizard

Crosstalk between the digestive and nervous systems

2012-08-01 to 2014-08-01 | Grant
European Molecular Biology Organization (Heidelberg, DE)
URL: https://app.dimensions.ai/details/grant/grant.6918426
GRANT_NUMBER:

8e314b51
Source: Self-asserted source
Irene Miguel-Aliaga via DimensionsWizard

Formation and Function of Insulin-producing Neurons in Drosophila.

2008-06-01 to 2012-10-31 | Grant
Wellcome Trust (London, GB)
URL: https://app.dimensions.ai/details/grant/grant.3641242
GRANT_NUMBER:

083559/Z/07/Z
Source: Self-asserted source
Irene Miguel-Aliaga via DimensionsWizard

Works (36)

Integrating the dynamic and energetic fields of metabolism and development

Development
2023-10-15 | Journal article
DOI: 10.1242/dev.202424
Contributors: Lydia Finley; Joshua Gendron; Irene Miguel-Aliaga; Jared Rutter
Source: check_circle
Crossref

An interview with Irene Miguel-Aliaga.

Development (Cambridge, England)
2020-01 | Journal article
DOI: 10.1242/dev.191650
PMID: 32527934
Source: check_circle
Researchfish

Food, microbes, sex and old age: on the plasticity of gastrointestinal innervation.

Current opinion in neurobiology
2020-01 | Journal article
DOI: 10.1016/j.conb.2019.12.004
PMID: 32028080
Source: check_circle
Researchfish

Steroidogenic control of liver metabolism through a nuclear receptor-network

Molecular Metabolism
2019-12 | Journal article
DOI: 10.1016/j.molmet.2019.09.007
Contributors: Alexandra Milona; Vittoria Massafra; Harmjan Vos; Jyoti Naik; Natalia Artigas; Helen A.B. Paterson; Ingrid T.G.W. Bijsmans; Ellen C.L. Willemsen; Jose M. Ramos Pittol; Irene Miguel-Aliaga et al.
Source: check_circle
Crossref

Anatomy and Physiology of the Digestive Tract of Drosophila melanogaster.

Genetics
2018-10 | Journal article
DOI: 10.1534/genetics.118.300224
PMID: 30287514
PMC: PMC6216580
Contributors: Miguel-Aliaga I; Jasper H; Lemaitre B
Source: Self-asserted source
Irene Miguel-Aliaga via Europe PubMed Central
grade
Preferred source (of 2)‎

Chinmo prevents transformer alternative splicing to maintain male sex identity.

PLoS genetics
2018-02 | Journal article
DOI: 10.1371/journal.pgen.1007203
PMID: 29389999
PMC: PMC5811060
Contributors: Grmai L; Hudry B; Miguel-Aliaga I; Bach EA
Source: Self-asserted source
Irene Miguel-Aliaga via Europe PubMed Central

Ret receptor tyrosine kinase sustains proliferation and tissue maturation in intestinal epithelia.

The EMBO journal
2017-09 | Journal article
DOI: 10.15252/embj.201696247
PMID: 28899900
PMC: PMC5641678
Contributors: Perea D; Guiu J; Hudry B; Konstantinidou C; Milona A; Hadjieconomou D; Carroll T; Hoyer N; Natarajan D; Kallijärvi J et al.
Source: Self-asserted source
Irene Miguel-Aliaga via Europe PubMed Central

The sexual identity of adult intestinal stem cells controls organ size and plasticity.

Nature
2016-02 | Journal article
DOI: 10.1038/nature16953
PMID: 26887495
PMC: PMC4800002
Contributors: Hudry B; Khadayate S; Miguel-Aliaga I
Source: Self-asserted source
Irene Miguel-Aliaga via Europe PubMed Central

Endocrine remodelling of the adult intestine sustains reproduction in Drosophila.

eLife
2015-07 | Journal article
DOI: 10.7554/eLife.06930
PMID: 26216039
PMC: PMC4515472
Contributors: Reiff T; Jacobson J; Cognigni P; Antonello Z; Ballesta E; Tan KJ; Yew JY; Dominguez M; Miguel-Aliaga I
Source: Self-asserted source
Irene Miguel-Aliaga via Europe PubMed Central

The Ret receptor regulates sensory neuron dendrite growth and integrin mediated adhesion.

eLife
2015-03 | Journal article
DOI: 10.7554/elife.05491
PMID: 25764303
PMC: PMC4391025
Contributors: Soba P; Han C; Zheng Y; Perea D; Miguel-Aliaga I; Jan LY; Jan YN
Source: Self-asserted source
Irene Miguel-Aliaga via Europe PubMed Central

Spotting the differences: probing host/microbiota interactions with a dedicated software tool for the analysis of faecal outputs in Drosophila.

Journal of insect physiology
2014-06 | Journal article
DOI: 10.1016/j.jinsphys.2014.05.023
PMID: 24907675
PMC: PMC4194350
Contributors: Wayland MT; Defaye A; Rocha J; Jayaram SA; Royet J; Miguel-Aliaga I; Leulier F; Cognigni P
Source: Self-asserted source
Irene Miguel-Aliaga via Europe PubMed Central

Conserved mechanisms of tumorigenesis in the Drosophila adult midgut.

PloS one
2014-02 | Journal article
DOI: 10.1371/journal.pone.0088413
PMID: 24516653
PMC: PMC3916428
Contributors: Martorell Ò; Merlos-Suárez A; Campbell K; Barriga FM; Christov CP; Miguel-Aliaga I; Batlle E; Casanova J; Casali A
Source: Self-asserted source
Irene Miguel-Aliaga via Europe PubMed Central

Neuronal control of metabolism through nutrient-dependent modulation of tracheal branching.

Cell
2014-01 | Journal article
DOI: 10.1016/j.cell.2013.12.008
PMID: 24439370
PMC: PMC3898607
Contributors: Linneweber GA; Jacobson J; Busch KE; Hudry B; Christov CP; Dormann D; Yuan M; Otani T; Knust E; de Bono M et al.
Source: Self-asserted source
Irene Miguel-Aliaga via Europe PubMed Central

Local requirement of the Drosophila insulin binding protein imp-L2 in coordinating developmental progression with nutritional conditions.

Developmental biology
2013-06 | Journal article
DOI: 10.1016/j.ydbio.2013.06.008
PMID: 23773803
Contributors: Sarraf-Zadeh L; Christen S; Sauer U; Cognigni P; Miguel-Aliaga I; Stocker H; Köhler K; Hafen E
Source: Self-asserted source
Irene Miguel-Aliaga via Europe PubMed Central

The digestive tract of Drosophila melanogaster.

Annual review of genetics
2013-01 | Journal article
DOI: 10.1146/annurev-genet-111212-133343
PMID: 24016187
Contributors: Lemaitre B; Miguel-Aliaga I
Source: Self-asserted source
Irene Miguel-Aliaga via Europe PubMed Central

The flies of Icarus: science with wings in Crete.

EMBO reports
2012-10 | Journal article
DOI: 10.1038/embor.2012.154
PMID: 23059980
PMC: PMC3492721
Contributors: Miguel-Aliaga I; Oliver B; Teleman AA
Source: Self-asserted source
Irene Miguel-Aliaga via Europe PubMed Central

Regulation of locomotion and motoneuron trajectory selection and targeting by the Drosophila homolog of Olig family transcription factors.

Developmental biology
2012-07 | Journal article
DOI: 10.1016/j.ydbio.2012.06.027
PMID: 22796650
PMC: PMC3464432
Contributors: Oyallon J; Apitz H; Miguel-Aliaga I; Timofeev K; Ferreira L; Salecker I
Source: Self-asserted source
Irene Miguel-Aliaga via Europe PubMed Central

Remote control of renal physiology by the intestinal neuropeptide pigment-dispersing factor in Drosophila.

Proceedings of the National Academy of Sciences of the United States of America
2012-07 | Journal article
DOI: 10.1073/pnas.1200247109
PMID: 22778427
PMC: PMC3409758
Contributors: Talsma AD; Christov CP; Terriente-Felix A; Linneweber GA; Perea D; Wayland M; Shafer OT; Miguel-Aliaga I
Source: Self-asserted source
Irene Miguel-Aliaga via Europe PubMed Central

Enteric Neurons and Systemic Signals Couple Nutritional and Reproductive Status with Intestinal Homeostasis.

Cell metabolism
2012-01 | Journal article
DOI: 10.1016/j.cmet.2011.12.010
PMC: PMC3464425
Contributors: Cognigni P; Bailey A; Miguel-Aliaga I
Source: Self-asserted source
Irene Miguel-Aliaga via Europe PubMed Central

Nerveless and gutsy: intestinal nutrient sensing from invertebrates to humans.

Seminars in cell & developmental biology
2012-01 | Journal article
DOI: 10.1016/j.semcdb.2012.01.002
PMID: 22248674
PMC: PMC3712190
Contributors: Miguel-Aliaga I
Source: Self-asserted source
Irene Miguel-Aliaga via Europe PubMed Central

Why flies? Inexpensive public engagement exercises to explain the value of basic biomedical research on Drosophila melanogaster.

Advances in physiology education
2011-12 | Journal article
DOI: 10.1152/advan.00045.2011
PMID: 22139775
Contributors: Pulver SR; Cognigni P; Denholm B; Fabre C; Gu WX; Linneweber G; Prieto-Godino L; Urbancic V; Zwart M; Miguel-Aliaga I
Source: Self-asserted source
Irene Miguel-Aliaga via Europe PubMed Central

Segment-specific generation of Drosophila Capability neuropeptide neurons by multi-faceted Hox cues.

Developmental biology
2011-02 | Journal article
DOI: 10.1016/j.ydbio.2011.02.015
PMID: 21354130
PMC: PMC3094758
Contributors: Suska A; Miguel-Aliaga I; Thor S
Source: Self-asserted source
Irene Miguel-Aliaga via Europe PubMed Central

Enteric neurons and systemic signals couple nutritional and reproductive status with intestinal homeostasis.

Cell metabolism
2011-01 | Journal article
DOI: 10.1016/j.cmet.2010.12.010
PMID: 21195352
PMC: PMC3038267
Contributors: Cognigni P; Bailey AP; Miguel-Aliaga I
Source: Self-asserted source
Irene Miguel-Aliaga via Europe PubMed Central

Programmed cell death in the nervous system--a programmed cell fate?

Current opinion in neurobiology
2009-04 | Journal article
DOI: 10.1016/j.conb.2009.04.002
PMID: 19446451
Contributors: Miguel-Aliaga I; Thor S
Source: Self-asserted source
Irene Miguel-Aliaga via Europe PubMed Central

A fluorescent reporter of caspase activity for live imaging.

Proceedings of the National Academy of Sciences of the United States of America
2008-09 | Journal article
DOI: 10.1073/pnas.0806983105
PMID: 18779587
PMC: PMC2544551
Contributors: Bardet PL; Kolahgar G; Mynett A; Miguel-Aliaga I; Briscoe J; Meier P; Vincent JP
Source: Self-asserted source
Irene Miguel-Aliaga via Europe PubMed Central

Postmitotic specification of Drosophila insulinergic neurons from pioneer neurons.

PLoS biology
2008-03 | Journal article
DOI: 10.1371/journal.pbio.0060058
PMID: 18336071
PMC: PMC2265769
Contributors: Miguel-Aliaga I; Thor S; Gould AP
Source: Self-asserted source
Irene Miguel-Aliaga via Europe PubMed Central

A novel family of single VWC-domain proteins in invertebrates.

FEBS letters
2007-11 | Journal article
DOI: 10.1016/j.febslet.2007.10.016
PMID: 18028914
Contributors: Sheldon TJ; Miguel-Aliaga I; Gould AP; Taylor WR; Conklin D
Source: Self-asserted source
Irene Miguel-Aliaga via Europe PubMed Central

Specification of neuronal identities by feedforward combinatorial coding.

PLoS biology
2007-02 | Journal article
DOI: 10.1371/journal.pbio.0050037
PMID: 17298176
PMC: PMC1790951
Contributors: Baumgardt M; Miguel-Aliaga I; Karlsson D; Ekman H; Thor S
Source: Self-asserted source
Irene Miguel-Aliaga via Europe PubMed Central

Independent roles of the dachshund and eyes absent genes in BMP signaling, axon pathfinding and neuronal specification.

Development (Cambridge, England)
2004-11 | Journal article
DOI: 10.1242/dev.01447
PMID: 15525669
Contributors: Miguel-Aliaga I; Allan DW; Thor S
Source: Self-asserted source
Irene Miguel-Aliaga via Europe PubMed Central

Segment-specific prevention of pioneer neuron apoptosis by cell-autonomous, postmitotic Hox gene activity.

Development (Cambridge, England)
2004-11 | Journal article
DOI: 10.1242/dev.01521
PMID: 15537690
Contributors: Miguel-Aliaga I; Thor S
Source: Self-asserted source
Irene Miguel-Aliaga via Europe PubMed Central

Neuromuscular defects in a Drosophila survival motor neuron gene mutant.

Human molecular genetics
2003-06 | Journal article
DOI: 10.1093/hmg/ddg157
PMID: 12783845
Contributors: Chan YB; Miguel-Aliaga I; Franks C; Thomas N; Trülzsch B; Sattelle DB; Davies KE; van den Heuvel M
Source: Self-asserted source
Irene Miguel-Aliaga via Europe PubMed Central

Specification of neuropeptide cell identity by the integration of retrograde BMP signaling and a combinatorial transcription factor code.

Cell
2003-04 | Journal article
DOI: 10.1016/s0092-8674(03)00204-6
PMID: 12679036
Contributors: Allan DW; St Pierre SE; Miguel-Aliaga I; Thor S
Source: Self-asserted source
Irene Miguel-Aliaga via Europe PubMed Central

Cloning and developmental expression analysis of ltd-1, the Caenorhabditis elegans homologue of the mouse kyphoscoliosis (ky) gene.

Mechanisms of development
2002-09 | Journal article
DOI: 10.1016/s0925-4773(02)00182-x
PMID: 12204272
Contributors: Vargas JD; Culetto E; Ponting CP; Miguel-Aliaga I; Davies KE; Sattelle DB
Source: Self-asserted source
Irene Miguel-Aliaga via Europe PubMed Central

Disruption of SMN function by ectopic expression of the human SMN gene in Drosophila.

FEBS letters
2000-12 | Journal article
DOI: 10.1016/s0014-5793(00)02243-2
PMID: 11113446
Contributors: Miguel-Aliaga I; Chan YB; Davies KE; van den Heuvel M
Source: Self-asserted source
Irene Miguel-Aliaga via Europe PubMed Central

The Caenorhabditis elegans orthologue of the human gene responsible for spinal muscular atrophy is a maternal product critical for germline maturation and embryonic viability.

Human molecular genetics
1999-11 | Journal article
DOI: 10.1093/hmg/8.12.2133
PMID: 10545592
Contributors: Miguel-Aliaga I; Culetto E; Walker DS; Baylis HA; Sattelle DB; Davies KE
Source: Self-asserted source
Irene Miguel-Aliaga via Europe PubMed Central

Characterization of a gene encoding survival motor neuron (SMN)-related protein, a constituent of the spliceosome complex.

Human molecular genetics
1998-12 | Journal article
DOI: 10.1093/hmg/7.13.2149
PMID: 9817934
Contributors: Talbot K; Miguel-Aliaga I; Mohaghegh P; Ponting CP; Davies KE
Source: Self-asserted source
Irene Miguel-Aliaga via Europe PubMed Central

Peer review (17 reviews for 8 publications/grants)

Review activity for Biology of sex differences. (2)
Review activity for Cell. (1)
Review activity for Developmental cell. (2)
Review activity for Nature (6)
Review activity for Nature communications (1)
Review activity for Nature metabolism. (2)
Review activity for PLoS biology. (2)
Review activity for Science. (1)
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