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Shenzhen University: Shenzhen City, CN

2015-12-07 to present (School of medicine)
Employment
Source: Self-asserted source
Jia-Jie Chen

Works (21)

Histone acetylation alteration by KAT6A inhibitor WM-1119 suppresses IgE-mediated mast cell activation and allergic inflammation via reduction in AP-1 signaling

Biochemical Pharmacology
2025-02 | Journal article
DOI: 10.1016/j.bcp.2024.116732
Contributors: Yu-Xin Jiao; Yan-Mei Zhou; Zi-Wen Zhou; Yong He; Shan Liu; Xue-Ting Xu; Kunmei Ji; Jia-Jie Chen
Source: check_circle
Crossref

Inhibition of c-Fos expression attenuates IgE-mediated mast cell activation and allergic inflammation by counteracting an inhibitory AP1/Egr1/IL-4 axis

2024-01-30 | Preprint
DOI: 10.22541/au.170664614.43394454/v1
Contributors: Hui-Na Wang; Kunmei Ji; Li-Na Zhang; Chu-Chu Xie; Wei-Yong Li; Zhen-Fu Zhao; Jia-Jie Chen
Source: check_circle
Crossref

Natural isoflavone formononetin inhibits IgE-mediated mast cell activation and allergic inflammation by increasing IgE receptor degradation

Food & Function
2023 | Journal article
DOI: 10.1039/D2FO03997D
Contributors: Zi-Wen Zhou; Kunmei Ji; Xue-Yan Zhu; Xin-Ying Wu; Ruo-Tong Lin; Chu-Chu Xie; Ze-Lang Cai; Jia-Jie Chen
Source: check_circle
Crossref

Identification of an immunodominant IgE epitope of Der f 40, a novel allergen of Dermatophagoides farinae

World Allergy Organization Journal
2023-08 | Journal article
DOI: 10.1016/j.waojou.2023.100804
Contributors: Ze-Lang Cai; Shan Liu; Wei-Yong Li; Zi-Wen Zhou; Wan-Zhen Hu; Jia-Jie Chen; Kunmei Ji
Source: check_circle
Crossref

Formononetin Inhibits Mast Cell Degranulation to Ameliorate Compound 48/80-Induced Pseudoallergic Reactions

Molecules
2023-07-07 | Journal article
DOI: 10.3390/molecules28135271
Contributors: Zi-Wen Zhou; Xue-Yan Zhu; Shu-Ying Li; Si-En Lin; Yu-Han Zhu; Kunmei Ji; Jia-Jie Chen
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Flavoring agent dihydrocoumarin alleviates IgE-mediated mast cell activation and allergic inflammation

Food & Function
2022 | Journal article
DOI: 10.1039/D2FO00190J
Contributors: Chu-Chu Xie; Bo-Ping Zhang; Hui-Na Wang; Wei-Yong Li; Ze-Lang Cai; Yong He; Kunmei Ji; Jia-Jie Chen
Source: check_circle
Crossref

Plant-Derived Molecule 4-Methylumbelliferone Suppresses FcεRI-Mediated Mast Cell Activation and Allergic Inflammation

Molecules
2022-02-27 | Journal article
DOI: 10.3390/molecules27051577
Contributors: Hui-Na Wang; Qiu-An Xiang; Hao-Hui Lin; Jie-Ning Chen; Wen-Jie Guo; Wan-Meng Guo; Xiang-Ning Yue; Zhen-Fu Zhao; Kunmei Ji; Jia-Jie Chen
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Inhibition of c-Fos expression attenuates IgE-mediated mast cell activation and allergic inflammation by counteracting an inhibitory AP1/Egr1/IL-4 axis

Journal of Translational Medicine
2021-12 | Journal article
DOI: 10.1186/s12967-021-02932-0
Contributors: Hui-Na Wang; Kunmei Ji; Li-Na Zhang; Chu-Chu Xie; Wei-Yong Li; Zhen-Fu Zhao; Jia-Jie Chen
Source: check_circle
Crossref

Chromosome-level assembly of Dermatophagoides farinae genome and transcriptome reveals two novel allergens Der f 37 and Der f 39

World Allergy Organization Journal
2021-10 | Journal article
DOI: 10.1016/j.waojou.2021.100590
Contributors: Jiajie Chen; Zelang Cai; Dingding Fan; Jiayu Hu; Yibo Hou; Yongsen He; Zhen Zhang; Zhenfu Zhao; Pan Gao; Wanzhen Hu et al.
Source: check_circle
Crossref

Inhibition of c-Fos expression attenuates IgE-mediated mast cell activation and allergic inflammation by counteracting an inhibitory AP1/Egr1/IL-4 axis

2021-03-08 | Other
DOI: 10.21203/rs.3.rs-297872/v1
Contributors: Hui-Na Wang; Kunmei Ji; Li-Na Zhang; Chu-Chu Xie; Wei-Yong Li; Zhen-Fu Zhao; Jia-Jie Chen
Source: check_circle
Crossref

The antipsychotic drug pimozide inhibits IgE-mediated mast cell degranulation and migration

International Immunopharmacology
2020-07 | Journal article
DOI: 10.1016/j.intimp.2020.106500
Part of ISSN: 1567-5769
Source: Self-asserted source
Jia-Jie Chen

Aurora kinase inhibitor tozasertib suppresses mast cell activation in vitro and in vivo

British Journal of Pharmacology
2020-06 | Journal article
DOI: 10.1111/bph.15012
Contributors: Li‐Na Zhang; Kunmei Ji; Yue‐Tong Sun; Yi‐Bo Hou; Jia‐Jie Chen
Source: check_circle
Crossref

Ribonuclease T2 from Aspergillus fumigatus promotes T helper type 2 responses through M2 polarization of macrophages

International Journal of Molecular Medicine
2020-05-21 | Journal article
DOI: 10.3892/ijmm.2020.4613
Part of ISSN: 1107-3756
Part of ISSN: 1791-244X
Source: Self-asserted source
Jia-Jie Chen

CDK4/6 inhibitor palbociclib suppresses IgE-mediated mast cell activation

Journal of Translational Medicine
2019-12 | Journal article
DOI: 10.1186/s12967-019-2026-9
Contributors: Yi-Bo Hou; Kunmei Ji; Yue-Tong Sun; Li-Na Zhang; Jia-Jie Chen
Source: check_circle
Crossref

Identification of immunodominant IgE binding epitopes of Der p 24, a major allergen of Dermatophagoides pteronyssinus

Clinical and Translational Allergy
2019-12 | Journal article
DOI: 10.1186/s13601-019-0266-7
Part of ISSN: 2045-7022
Source: Self-asserted source
Jia-Jie Chen

Identification of immunodominant IgE epitopes of the major house dust mite allergen Der f 24

International Journal of Molecular Medicine
2019-09-18 | Journal article
DOI: 10.3892/ijmm.2019.4345
Part of ISSN: 1107-3756
Part of ISSN: 1791-244X
Source: Self-asserted source
Jia-Jie Chen

Antipsychotic agent pimozide promotes reversible proliferative suppression by inducing cellular quiescence in liver cancer

Oncology Reports
2019-07-11 | Journal article
DOI: 10.3892/or.2019.7229
Part of ISSN: 1021-335X
Part of ISSN: 1791-2431
Source: Self-asserted source
Jia-Jie Chen

In Vivo Murine Model of Leukemia Cell-Induced Spinal Bone Destruction

BioMed Research International
2017 | Journal article
DOI: 10.1155/2017/3521481
Contributors: Jia-Jie Chen; Wei Zhou; Nan Cai; Gang Chang
Source: check_circle
Crossref

The STAT3 inhibitor pimozide impedes cell proliferation and induces ROS generation in human osteosarcoma by suppressing catalase expression.

American journal of translational research
2017-08-15 | Journal article
PMID: 28861175
PMC: PMC5575198
Source: Self-asserted source
Jia-Jie Chen

The neuroleptic drug pimozide inhibits stem-like cell maintenance and tumorigenicity in hepatocellular carcinoma

Oncotarget
2017-03-14 | Journal article
DOI: 10.18632/oncotarget.4307
Part of ISSN: 1949-2553
Source: Self-asserted source
Jia-Jie Chen

The antipsychotic drug pimozide inhibits cell growth in prostate cancer through suppression of STAT3 activation

International Journal of Oncology
2016-01 | Journal article
DOI: 10.3892/ijo.2015.3229
Part of ISSN: 1019-6439
Part of ISSN: 1791-2423
Source: Self-asserted source
Jia-Jie Chen

Peer review (7 reviews for 5 publications/grants)

Review activity for Biochemical and biophysical research communications. (1)
Review activity for European journal of pharmacology. (1)
Review activity for International journal of biological macromolecules. (2)
Review activity for Phytomedicine. (1)
Review activity for The World Allergy Organization journal. (2)
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