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Employment (1)

University of North Carolina School of Medicine: Chapel Hill, North Carolina, US

2006-07-01 to present | Professor (Genetics, Pediatrics)
Employment
Source: Self-asserted source
Ian Davis

Education and qualifications (6)

Dana Farber Cancer Institute: Boston, MA, US

1999-07 to 2005-06 | Fellow (Pediatric Oncology)
Qualification
Source: Self-asserted source
Ian Davis

Children's Hospital Boston: Boston, MA, US

1998-07 to 1999-06 | Chief Resident (Medicine)
Qualification
Source: Self-asserted source
Ian Davis

Children's Hospital Boston: Boston, MA, US

1995-07 to 1998-06 | Resident (Medicine)
Qualification
Source: Self-asserted source
Ian Davis

Northwestern University Feinberg School of Medicine: Chicago, IL, US

1987-09 to 1995-06 | MD
Education
Source: Self-asserted source
Ian Davis

University of Illinois at Chicago: Chicago, IL, US

1989-09 to 1994-05 | PhD
Education
Source: Self-asserted source
Ian Davis

Northwestern University: Evanston, IL, US

1983-09 to 1987-06 | BA
Education
Source: Self-asserted source
Ian Davis

Works (50 of 70)

Items per page:
Page 1 of 2

Data from PBRM1 Inactivation Promotes Upregulation of Human Endogenous Retroviruses in a HIF-Dependent Manner

2023-04-04 | Preprint
Contributors: Mi Zhou; Janet Y. Leung; Kathryn H. Gessner; Austin J. Hepperla; Jeremy M. Simon; Ian J. Davis; William Y. Kim
Source: check_circle
Crossref

Data from PBRM1 Inactivation Promotes Upregulation of Human Endogenous Retroviruses in a HIF-Dependent Manner

2023-04-04 | Preprint
Contributors: Mi Zhou; Janet Y. Leung; Kathryn H. Gessner; Austin J. Hepperla; Jeremy M. Simon; Ian J. Davis; William Y. Kim
Source: check_circle
Crossref

Supplementary Data from PBRM1 Inactivation Promotes Upregulation of Human Endogenous Retroviruses in a HIF-Dependent Manner

2023-04-04 | Preprint
Contributors: Mi Zhou; Janet Y. Leung; Kathryn H. Gessner; Austin J. Hepperla; Jeremy M. Simon; Ian J. Davis; William Y. Kim
Source: check_circle
Crossref

Supplementary Data from PBRM1 Inactivation Promotes Upregulation of Human Endogenous Retroviruses in a HIF-Dependent Manner

2023-04-04 | Preprint
Contributors: Mi Zhou; Janet Y. Leung; Kathryn H. Gessner; Austin J. Hepperla; Jeremy M. Simon; Ian J. Davis; William Y. Kim
Source: check_circle
Crossref

Supplementary Figure from PBRM1 Inactivation Promotes Upregulation of Human Endogenous Retroviruses in a HIF-Dependent Manner

2023-04-04 | Preprint
Contributors: Mi Zhou; Janet Y. Leung; Kathryn H. Gessner; Austin J. Hepperla; Jeremy M. Simon; Ian J. Davis; William Y. Kim
Source: check_circle
Crossref

Supplementary Figure from PBRM1 Inactivation Promotes Upregulation of Human Endogenous Retroviruses in a HIF-Dependent Manner

2023-04-04 | Preprint
Contributors: Mi Zhou; Janet Y. Leung; Kathryn H. Gessner; Austin J. Hepperla; Jeremy M. Simon; Ian J. Davis; William Y. Kim
Source: check_circle
Crossref

PBRM1 Inactivation Promotes Upregulation of Human Endogenous Retroviruses in a HIF-Dependent Manner

Cancer Immunology Research
2022-03-01 | Journal article
Contributors: Mi Zhou; Janet Y. Leung; Kathryn H. Gessner; Austin J. Hepperla; Jeremy M. Simon; Ian J. Davis; William Y. Kim
Source: check_circle
Crossref

Radiation-Induced Phosphorylation of a Prion-Like Domain Regulates Transformation by FUS-CHOP.

Cancer research
2021-08-12 | Journal article
Source: Self-asserted source
Ian Davis

SPOP and OTUD7A Control EWS-FLI1 Protein Stability to Govern Ewing Sarcoma Growth.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
2021-06-01 | Journal article
Source: Self-asserted source
Ian Davis

HDAC inhibition results in widespread alteration of the histone acetylation landscape and BRD4 targeting to gene bodies.

Cell reports
2021-01-01 | Journal article
Source: Self-asserted source
Ian Davis

An optogenetic switch for the Set2 methyltransferase provides evidence for transcription-dependent and -independent dynamics of H3K36 methylation

Genome Research
2020-11 | Journal article
Contributors: Andrew M. Lerner; Austin J. Hepperla; Gregory R. Keele; Hashem A. Meriesh; Hayretin Yumerefendi; David Restrepo; Seth Zimmerman; James E. Bear; Brian Kuhlman; Ian J. Davis et al.
Source: check_circle
Crossref

Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples.

Nature communications
2020-09-21 | Journal article
Source: Self-asserted source
Ian Davis

Accelerated aging among childhood, adolescent, and young adult cancer survivors is evidenced by increased expression of p16<sup>INK4a</sup> and frailty.

Cancer
2020-08-24 | Journal article
Source: Self-asserted source
Ian Davis

Discrete Adaptive Responses to MEK Inhibitor in Subpopulations of Triple-Negative Breast Cancer.

Molecular cancer research : MCR
2020-08-04 | Journal article
Source: Self-asserted source
Ian Davis

Pan-cancer analysis of whole genomes.

Nature
2020-02-05 | Journal article
Source: Self-asserted source
Ian Davis

EWSR1-FLI1 activation of the cancer/testis antigen FATE1 promotes Ewing sarcoma survival.

Molecular and cellular biology
2019-04-29 | Journal article
Source: Self-asserted source
Ian Davis

Casein Kinase II Phosphorylation of Spt6 Enforces Transcriptional Fidelity by Maintaining Spn1-Spt6 Interaction.

Cell reports
2018-12-01 | Journal article
Source: Self-asserted source
Ian Davis

PBRM1 bromodomains variably influence nucleosome interactions and cellular function.

The Journal of biological chemistry
2018-07-09 | Journal article
Source: Self-asserted source
Ian Davis

CHD4 and the NuRD complex directly control cardiac sarcomere formation.

Proceedings of the National Academy of Sciences of the United States of America
2018-06-11 | Journal article
Source: Self-asserted source
Ian Davis

Spt6 Association with RNA Polymerase II Directs mRNA Turnover During Transcription.

Molecular cell
2018-06-01 | Journal article
Source: Self-asserted source
Ian Davis

SETD2 Haploinsufficiency for Microtubule Methylation Is an Early Driver of Genomic Instability in Renal Cell Carcinoma.

Cancer research
2018-05-03 | Journal article
Source: Self-asserted source
Ian Davis

Cavitation Enhancement Increases the Efficiency and Consistency of Chromatin Fragmentation from Fixed Cells for Downstream Quantitative Applications.

Biochemistry
2018-04-25 | Journal article
Source: Self-asserted source
Ian Davis

Comprehensive and Integrated Genomic Characterization of Adult Soft Tissue Sarcomas.

Cell
2017-11-01 | Journal article
Source: Self-asserted source
Ian Davis

H3K36 Methylation Regulates Nutrient Stress Response in Saccharomyces cerevisiae by Enforcing Transcriptional Fidelity.

Cell reports
2017-06-01 | Journal article
Source: Self-asserted source
Ian Davis

SETting the Stage for Cancer Development: SETD2 and the Consequences of Lost Methylation.

Cold Spring Harbor perspectives in medicine
2017-05-01 | Journal article
Source: Self-asserted source
Ian Davis

Widespread Chromatin Accessibility at Repetitive Elements Links Stem Cells with Human Cancer.

Cell reports
2016-11-01 | Journal article
Source: Self-asserted source
Ian Davis

Structure/Function Analysis of Recurrent Mutations in SETD2 Protein Reveals a Critical and Conserved Role for a SET Domain Residue in Maintaining Protein Stability and Histone H3 Lys-36 Trimethylation.

The Journal of biological chemistry
2016-08-15 | Journal article
Source: Self-asserted source
Ian Davis

Dual Chromatin and Cytoskeletal Remodeling by SETD2.

Cell
2016-08-01 | Journal article
Source: Self-asserted source
Ian Davis

Post-transplant lymphoproliferative disorder of the pediatric airway: Presentation and management.

International journal of pediatric otorhinolaryngology
2016-04-30 | Journal article
Source: Self-asserted source
Ian Davis

International cancer seminars: a focus on kidney cancer.

Annals of oncology : official journal of the European Society for Medical Oncology
2016-04-29 | Journal article
Source: Self-asserted source
Ian Davis

High-throughput small molecule screen identifies inhibitors of aberrant chromatin accessibility.

Proceedings of the National Academy of Sciences of the United States of America
2016-02-29 | Journal article
Source: Self-asserted source
Ian Davis

The Cardiac TBX5 Interactome Reveals a Chromatin Remodeling Network Essential for Cardiac Septation.

Developmental cell
2016-02-01 | Journal article
Source: Self-asserted source
Ian Davis

Subtumoral analysis of PRINT nanoparticle distribution reveals targeting variation based on cellular and particle properties.

Nanomedicine : nanotechnology, biology, and medicine
2016-01-07 | Journal article
Source: Self-asserted source
Ian Davis

A Role for Widely Interspaced Zinc Finger (WIZ) in Retention of the G9a Methyltransferase on Chromatin.

The Journal of biological chemistry
2015-09-03 | Journal article
Source: Self-asserted source
Ian Davis

Linking germline and somatic variation in Ewing sarcoma.

Nature genetics
2015-09-01 | Journal article
Source: Self-asserted source
Ian Davis

FOXP1 potentiates Wnt/β-catenin signaling in diffuse large B cell lymphoma.

Science signaling
2015-02-03 | Journal article
Source: Self-asserted source
Ian Davis

LKB1 loss in melanoma disrupts directional migration toward extracellular matrix cues.

The Journal of cell biology
2014-10-01 | Journal article
Source: Self-asserted source
Ian Davis

BRG1/SMARCA4 inactivation promotes non-small cell lung cancer aggressiveness by altering chromatin organization.

Cancer research
2014-08-12 | Journal article
Source: Self-asserted source
Ian Davis

PTEN deficiency mediates a reciprocal response to IGFI and mTOR inhibition.

Molecular cancer research : MCR
2014-07-03 | Journal article
Source: Self-asserted source
Ian Davis

A chemical tool for in vitro and in vivo precipitation of lysine methyltransferase G9a.

ChemMedChem
2014-01-17 | Journal article
Source: Self-asserted source
Ian Davis

Loss of Arp2/3 induces an NF-κB-dependent, nonautonomous effect on chemotactic signaling.

The Journal of cell biology
2013-12-01 | Journal article
Source: Self-asserted source
Ian Davis

Variation in chromatin accessibility in human kidney cancer links H3K36 methyltransferase loss with widespread RNA processing defects.

Genome research
2013-10-24 | Journal article
Source: Self-asserted source
Ian Davis

The open chromatin landscape of Kaposi's sarcoma-associated herpesvirus.

Journal of virology
2013-08-28 | Journal article
Source: Self-asserted source
Ian Davis

Biomarkers in Ewing Sarcoma: The Promise and Challenge of Personalized Medicine. A Report from the Children's Oncology Group.

Frontiers in oncology
2013-06-06 | Journal article
Source: Self-asserted source
Ian Davis

EWS and RE1-Silencing Transcription Factor Inhibit Neuronal Phenotype Development and Oncogenic Transformation in Ewing Sarcoma.

Genes & cancer
2013-05-01 | Journal article
Source: Self-asserted source
Ian Davis

Valproic acid reduces the tolerability of temsirolimus in children and adolescents with solid tumors.

Anti-cancer drugs
2013-04-01 | Journal article
Source: Self-asserted source
Ian Davis

A detailed protocol for formaldehyde-assisted isolation of regulatory elements (FAIRE).

Current protocols in molecular biology
2013-01-01 | Journal article
Source: Self-asserted source
Ian Davis

State of the science: an update on renal cell carcinoma.

Molecular cancer research : MCR
2012-05-25 | Journal article
Source: Self-asserted source
Ian Davis

Tivantinib (ARQ 197), a selective inhibitor of MET, in patients with microphthalmia transcription factor-associated tumors: results of a multicenter phase 2 trial.

Cancer
2012-05-17 | Journal article
Source: Self-asserted source
Ian Davis

Using formaldehyde-assisted isolation of regulatory elements (FAIRE) to isolate active regulatory DNA.

Nature protocols
2012-01-19 | Journal article
Source: Self-asserted source
Ian Davis
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