Personal information

Prodrug, Phosphonamidate, Aryl phosphonates, Butyrophilin, BTN3A1, Phosphoantigen, Medicinal chemistry, Organic synthesis
United States

Activities

Education and qualifications (3)

University of Iowa: Iowa City, IA, US

2015-06 to present | PhD candidate (Chemistry)
Education
Source: Self-asserted source
Nicholas Lentini

Campbell University: Buies Creek, NC, US

2012-01 to 2015-05 | B.S. Chemistry (Chemistry)
Education
Source: Self-asserted source
Nicholas Lentini

Campbell University: Buies Creek, NC, US

2012-01 to 2015-05 | B.S. Mathematics (Mathematics)
Education
Source: Self-asserted source
Nicholas Lentini

Works (6)

Mechanism of bisphosphonate-related osteonecrosis of the jaw (BRONJ) revealed by targeted removal of legacy bisphosphonate from jawbone using competing inert hydroxymethylene diphosphonate

eLife
2022-08-26 | Journal article
Contributors: Hiroko Okawa; Takeru Kondo; Akishige Hokugo; Philip Cherian; Jesus J Campagna; Nicholas A Lentini; Eric C Sung; Samantha Chiang; Yi-Ling Lin; Frank H Ebetino et al.
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Crossref

Efficiency of bis-amidate phosphonate prodrugs

Bioorganic & Medicinal Chemistry Letters
2022-06 | Journal article
Contributors: Nicholas A. Lentini; Xueting Huang; Megan A. Schladetsch; Chia-Hung Christine Hsiao; David F. Wiemer; Andrew J. Wiemer
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Crossref

Synthesis and Metabolism of BTN3A1 Ligands: Studies on Modifications of the Allylic Alcohol

ACS Medicinal Chemistry Letters
2021-01-14 | Journal article
Contributors: Nicholas A. Lentini; Chloe M. Schroeder; Nyema M. Harmon; Xueting Huang; Megan A. Schladetsch; Benjamin J. Foust; Michael M. Poe; Chia-Hung Christine Hsiao; Andrew J. Wiemer; David F. Wiemer
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Crossref

Synthesis and Bioactivity of the Alanyl Phosphonamidate Stereoisomers Derived from a Butyrophilin Ligand

ACS Medicinal Chemistry Letters
2019-09-12 | Journal article
Contributors: Nicholas A. Lentini; Chia-Hung Christine Hsiao; George B. Crull; Andrew J. Wiemer; David F. Wiemer
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Crossref

Phosphonamidate Prodrugs of a Butyrophilin Ligand Display Plasma Stability and Potent Vγ9 Vδ2 T Cell Stimulation

Journal of Medicinal Chemistry
2018-10-11 | Journal article
Contributors: Nicholas A. Lentini; Benjamin J. Foust; Chia-Hung Christine Hsiao; Andrew J. Wiemer; David F. Wiemer
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Crossref

Mixed Aryl Phosphonate Prodrugs of a Butyrophilin Ligand

ACS Medicinal Chemistry Letters
2017-08 | Journal article
Part of ISSN: 1948-5875
Contributors: Benjamin J. Foust; Michael M. Poe; Nicholas A. Lentini; Chia-Hung Christine Hsiao; Andrew J. Wiemer; David F. Wiemer
Source: Self-asserted source
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