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Candida albicans, Chromatin, Epigenetics, Fungal Biology, Second generation biofuels, Genome Plasticity

Activities

Employment (2)

University of Kent: Canterbury, Kent, GB

2013-07-01 to present | Reader/ Group Leader (School of Biosciences)
Employment
Source: Self-asserted source
Alessia Buscaino

Wellcome Centre for Cell Biology: Edinburgh, Edinburgh, GB

2005-11-01 to 2013-05-20 | EMBO/ Wellcome Postdoctoral Fellow
Employment
Source: Self-asserted source
Alessia Buscaino

Education and qualifications (1)

European Molecular Biology Laboratory: Heidelberg, Baden-Württemberg, DE

2001-09-01 to 2005-09-01 | PhD (Gene Expression Programme)
Education
Source: Self-asserted source
Alessia Buscaino

Funding (2)

Epigenetics of stress-induced genome instability in the human fungal pathogen Candida albicans

2020-09-24 to 2024-01-24 | Grant
Biotechnology and Biological Sciences Research Council (Swindon, GB)
GRANT_NUMBER: BB/T006315/1
Source: Self-asserted source
Alessia Buscaino via DimensionsWizard

Improving second-generation biofuel production: exploiting the natural diversity of S. stipitis

2020-09-18 to 2024-09-29 | Grant
Biotechnology and Biological Sciences Research Council (Swindon, GB)
GRANT_NUMBER: 2449782
Source: Self-asserted source
Alessia Buscaino via DimensionsWizard

Works (28)

Transposon load and RNAi loss synergize to drive intraspecies diversity in Cryptococcus

Proceedings of the National Academy of Sciences
2024-12-24 | Journal article
Contributors: Elise Iracane; Alessia Buscaino
Source: check_circle
Crossref

Identification of an active RNAi pathway in Candida albicans

Proceedings of the National Academy of Sciences
2024-04-23 | Journal article
Contributors: Elise Iracane; Cristina Arias-Sardá; Corinne Maufrais; Iuliana V. Ene; Christophe d’Enfert; Alessia Buscaino
Source: check_circle
Crossref

Deletion of the Candida albicans TLO gene family using CRISPR-Cas9 mutagenesis allows characterisation of functional differences in α-, β- and γ- TLO gene function

PLOS Genetics
2023-12-04 | Journal article
Contributors: Jessica Fletcher; Anja Forche; James O’Connor-Moneley; Dean Frawley; Peter R. Flanagan; Leenah Alaalm; Pilar Menendez-Manjon; Samuel Vega Estevez; Shane Hendricks; Andrew L. Woodruff et al.
Source: check_circle
Crossref

Stress combined with loss of the Candida albicans SUMO protease Ulp2 triggers selection of aneuploidy via a two-step process

PLOS Genetics
2022-12-27 | Journal article
Contributors: Marzia Rizzo; Gary P. Moran; Natthapon Soisangwan; Samuel Vega-Estevez; Robert Jordan Price; Chloe Uyl; Elise Iracane; Matt Shaw; Jan Soetaert; Anna Selmecki et al.
Source: check_circle
Crossref

The SUMO protease Ulp2 regulates genome stability and drug resistance in the human fungal pathogen Candida albicans

2021-12-07 | Preprint
Contributors: Marzia Rizzo; Natthapon Soisangwan; Jan Soetaert; Samuel Vega-Estevez; Anna Selmecki; Alessia Buscaino
Source: check_circle
Crossref

On and Off: Epigenetic Regulation of C. albicans Morphological Switches

Pathogens
2021-11-11 | Journal article
Contributors: Elise Iracane; Samuel Vega-Estévez; Alessia Buscaino
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

The Genome of the CTG(Ser1) Yeast <i>Scheffersomyces stipitis</i> Is Plastic.

mBio
2021-09 | Journal article
Contributors: Vega-Estévez S; Armitage A; Bates HJ; Harrison RJ; Buscaino A
Source: Self-asserted source
Alessia Buscaino via Europe PubMed Central
grade
Preferred source (of 2)‎

The genome of the CTG(Ser1) yeast Scheffersomyces stipitisis plastic

2021-02-16 | Preprint
Contributors: Samuel Vega Estevez; Andrew Armitage; Helen J. Bates; Richard J. Harrison; Alessia Buscaino
Source: check_circle
Crossref

Chromatin-Mediated Regulation of Genome Plasticity in Human Fungal Pathogens

Genes
2019-10-28 | Journal article
Part of ISSN: 2073-4425
Source: Self-asserted source
Alessia Buscaino
grade
Preferred source (of 2)‎

Chromatin Profiling of the Repetitive and Nonrepetitive Genomes of the Human Fungal Pathogen Candida albicans

mBio
2019-07-23 | Journal article
Part of ISSN: 2150-7511
Source: Self-asserted source
Alessia Buscaino
grade
Preferred source (of 2)‎

The fungal-specific Hda2 and Hda3 proteins regulate morphological switches in the human fungal pathogenCandida albicans

2018-06-06 | Other
Contributors: Misty R. Peterson; Robert Jordan Price; Sarah Gourlay; Alisha May; Jennifer Tullet; Alessia Buscaino
Source: check_circle
Crossref

Candida albicans repetitive elements display epigenetic diversity and plasticity.

2016 | Journal article
Contributors: Freire-Benéitez V; Price RJ; Tarrant D; Berman J; Buscaino A
Source: Self-asserted source
Alessia Buscaino via Europe PubMed Central

E-MTAB-4488 - RNA sequencing analysis of wild type strain and sir double deletion mutant strain of Candida albicans

2016 | Dataset
OTHER-ID:

E-MTAB-4488

Source: check_circle
EMBL-EBI

E-MTAB-4622 - Candida albicans BWP17 Wild-type strain 39oC growth

2016 | Dataset
OTHER-ID:

E-MTAB-4622

Source: check_circle
EMBL-EBI

The Chromatin of Candida albicans Pericentromeres Bears Features of Both Euchromatin and Heterochromatin.

2016 | Journal article
Contributors: Freire-Benéitez V; Price RJ; Buscaino A
Source: Self-asserted source
Alessia Buscaino via Europe PubMed Central

Sir2 regulates stability of repetitive domains differentially in the human fungal pathogen Candida albicans.

2016-07 | Journal article
Contributors: Freire-Benéitez V; Gourlay S; Berman J; Buscaino A
Source: Self-asserted source
Alessia Buscaino via Europe PubMed Central

The RFTS domain of Raf2 is required for Cul4 interaction and heterochromatin integrity in fission yeast.

2014 | Journal article
DOI:

10.1371/journal.pone.0104161

PMID:

25090107

PMC:

PMC4121317

Contributors: White SA; Buscaino A; Sanchez-Pulido L; Ponting CP; Nowicki MW; Allshire RC
Source: Self-asserted source
Alessia Buscaino via Europe PubMed Central

Distinct roles for Sir2 and RNAi in centromeric heterochromatin nucleation, spreading and maintenance.

2013-05 | Journal article
DOI:

10.1038/emboj.2013.72

PMID:

23572080

PMC:

PMC3642681

Contributors: Buscaino A; Lejeune E; Audergon P; Hamilton G; Pidoux A; Allshire RC
Source: Self-asserted source
Alessia Buscaino via Europe PubMed Central

Raf1 Is a DCAF for the Rik1 DDB1-like protein and has separable roles in siRNA generation and chromatin modification.

2012-02 | Journal article
DOI:

10.1371/journal.pgen.1002499

PMID:

22319459

PMC:

PMC3271066

Contributors: Buscaino A; White SA; Houston DR; Lejeune E; Simmer F; de Lima Alves F; Diyora PT; Urano T; Bayne EH; Rappsilber J et al.
Source: Self-asserted source
Alessia Buscaino via Europe PubMed Central

Building centromeres: home sweet home or a nomadic existence?

2010-04 | Journal article
DOI:

10.1016/j.gde.2010.01.006

PMID:

20206496

Contributors: Buscaino A; Allshire R; Pidoux A
Source: Self-asserted source
Alessia Buscaino via Europe PubMed Central

Hairpin RNA induces secondary small interfering RNA synthesis and silencing in trans in fission yeast.

2010-02 | Journal article
DOI:

10.1038/embor.2009.273

PMID:

20062003

PMC:

PMC2828748

Contributors: Simmer F; Buscaino A; Kos-Braun IC; Kagansky A; Boukaba A; Urano T; Kerr AR; Allshire RC
Source: Self-asserted source
Alessia Buscaino via Europe PubMed Central

Molecular biology: silencing unlimited.

2006-08 | Journal article
DOI:

10.1016/j.cub.2006.07.033

PMID:

16920610

Contributors: Almeida R; Buscaino A; Allshire RC
Source: Self-asserted source
Alessia Buscaino via Europe PubMed Central

Nuclear pore components are involved in the transcriptional regulation of dosage compensation in Drosophila.

2006-03 | Journal article
DOI:

10.1016/j.molcel.2006.02.007

PMID:

16543150

Contributors: Mendjan S; Taipale M; Kind J; Holz H; Gebhardt P; Schelder M; Vermeulen M; Buscaino A; Duncan K; Mueller J et al.
Source: Self-asserted source
Alessia Buscaino via Europe PubMed Central

A general precursor ion-like scanning mode on quadrupole-TOF instruments compatible with chromatographic separation.

2006-01 | Journal article
DOI:

10.1002/pmic.200501332

PMID:

16302280

Contributors: Niggeweg R; Köcher T; Gentzel M; Buscaino A; Taipale M; Akhtar A; Wilm M
Source: Self-asserted source
Alessia Buscaino via Europe PubMed Central

Structure of the chromo barrel domain from the MOF acetyltransferase.

2005-09 | Journal article
DOI:

10.1074/jbc.M501347200

PMID:

15964847

Contributors: Nielsen PR; Nietlispach D; Buscaino A; Warner RJ; Akhtar A; Murzin AG; Murzina NV; Laue ED
Source: Self-asserted source
Alessia Buscaino via Europe PubMed Central

MOF-regulated acetylation of MSL-3 in the Drosophila dosage compensation complex.

2003-05 | Journal article
DOI:

10.1016/S1097-2765(03)00140-0

PMID:

12769850

Contributors: Buscaino A; Köcher T; Kind JH; Holz H; Taipale M; Wagner K; Wilm M; Akhtar A
Source: Self-asserted source
Alessia Buscaino via Europe PubMed Central

Identification of the enhancer binding protein MBF-1 of the sea urchin modulator alpha-H2A histone gene.

2002-07 | Journal article
DOI:

10.1016/S0006-291X(02)00708-8

PMID:

12150981

Contributors: Alessandro C; Di Simone P; Buscaino A; Anello L; Palla F; Spinelli G
Source: Self-asserted source
Alessia Buscaino via Europe PubMed Central

X-chromosome targeting and dosage compensation are mediated by distinct domains in MSL-3

Journal article
DOI:

10.1038/sj.embor.7400658

Source: Self-asserted source
Alessia Buscaino

Peer review (2 reviews for 2 publications/grants)

Review activity for Microbiology. (1)
Review activity for Nature communications (1)