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Employment (1)

Indian Institute of Technology Roorkee: Roorkee, Uttarakhand, IN

2007-01-01 to 2034-07-01 | Professor (Indian Institute of Technology Roorkee)
Employment
Source: Self-asserted source
Shailly Tomar

Education and qualifications (3)

Purdue University Purdue Policy Research Institute: West Lafayette, US

2001-06-01 to 2006-05-31 | Ph.D (Department of Biological Sciences)
Education
Source: Self-asserted source
Shailly Tomar

All-India Institute of Medical Sciences: Delhi, IN

1999-07-01 to 2001-06-30 | M.Sc. (Biophysics)
Education
Source: Self-asserted source
Shailly Tomar

University of Delhi: New Delhi, IN

1996-07-01 to 1999-06-30 | B.Sc. (Botany)
Education
Source: Self-asserted source
Shailly Tomar

Works (42)

Transformative approaches in SARS-CoV-2 management: Vaccines, therapeutics and future direction

Virology
2025-03 | Journal article
DOI: 10.1016/j.virol.2025.110394
Contributors: Ankita Saha; Shweta Choudhary; Priyanshu Walia; Pravindra Kumar; Shailly Tomar
Source: check_circle
Crossref

Designing and bioengineering of CDRs with higher affinity against receptor-binding domain (RBD) of SARS-CoV-2 Omicron variant

International Journal of Biological Macromolecules
2025-02 | Journal article
DOI: 10.1016/j.ijbiomac.2024.138751
Contributors: Vishakha Singh; Shweta Choudhary; Mandar Bhutkar; Sanketkumar Nehul; Sabika Ali; Jitin Singla; Pravindra Kumar; Shailly Tomar
Source: check_circle
Crossref

Disruption of Molecular Interactions between the G3BP1 Stress Granule Host Protein and the Nucleocapsid (NTD-N) Protein Impedes SARS-CoV-2 Virus Replication

Biochemistry
2025-02-18 | Journal article
DOI: 10.1021/acs.biochem.4c00536
Contributors: Preeti Dhaka; Ankur Singh; Sanketkumar Nehul; Shweta Choudhary; Prasan Kumar Panda; Gaurav Kumar Sharma; Pravindra Kumar; Shailly Tomar
Source: check_circle
Crossref

Bioinformatics Databases and Tools Available for the Development of Antiviral Drugs

2024 | Book chapter
DOI: 10.1007/978-981-99-9195-2_2
Contributors: Ankur Singh; Preeti Dhaka; Pravindra Kumar; Shailly Tomar; Jitin Singla
Source: check_circle
Crossref

Mechanistic insights into the inhibition of dengue virus NS5 methyltransferase by herbacetin

2024-10-14 | Preprint
DOI: 10.1101/2024.10.14.618121
Contributors: Mandar Bhutkar; Shalja Verma; Vishakha Singh; Pravindra Kumar; Shailly Tomar
Source: check_circle
Crossref

Structural insights into the RNA binding inhibitors of the C-terminal domain of the SARS-CoV-2 nucleocapsid

2024-10-11 | Preprint
DOI: 10.1101/2024.10.11.617762
Contributors: Preeti Dhaka; Jai Krishna Mahto; Ankur Singh; Pravindra Kumar; Shailly Tomar
Source: check_circle
Crossref

Structural and mechanistic insights into Main protease (Mpro) dimer interface destabilization inhibitor: Unveiling new therapeutic avenues against SARS-CoV-2

2024-10-07 | Preprint
DOI: 10.26434/chemrxiv-2023-qf6rb-v3
Contributors: Ankur Singh; Kuldeep jangid; Sanketkumar Nehul; Preeti Dhaka; Ruchi Rani; Akshay Pareek; Gaurav Sharma; Pravindra Kumar; Shailly Tomar
Source: check_circle
Crossref

Viral methyltransferase inhibitors: berbamine, venetoclax, and ponatinib as efficacious antivirals against chikungunya virus

Archives of Biochemistry and Biophysics
2024-09 | Journal article
DOI: 10.1016/j.abb.2024.110111
Contributors: Mandar Bhutkar; Ankita Saha; Shailly Tomar
Source: check_circle
Crossref

Designing and bioengineering of CDRs with higher affinity against receptor-binding domain (RBD) of SARS-CoV-2 Omicron variant

2024-09-20 | Preprint
DOI: 10.1101/2024.09.19.613860
Contributors: Vishakha Singh; Shweta Choudhary; Mandar Bhutkar; Sanketkumar Nehul; Sabika Ali; Jitin Singla; Pravindra Kumar; Shailly Tomar
Source: check_circle
Crossref

Unraveling antiviral efficacy of multifunctional immunomodulatory triterpenoids against SARS‐COV‐2 targeting main protease and papain‐like protease

IUBMB Life
2024-05 | Journal article
DOI: 10.1002/iub.2793
Contributors: Shweta Choudhary; Sanketkumar Nehul; Ankur Singh; Prasan Kumar Panda; Pravindra Kumar; Gaurav Kumar Sharma; Shailly Tomar
Source: check_circle
Crossref

Viral methyltransferase inhibitors: berbamine, venetoclax, and ponatinib as efficacious antivirals against Chikungunya virus

2024-05-19 | Preprint
DOI: 10.1101/2024.05.19.594723
Contributors: Mandar Bhutkar; Ankita Saha; Shailly Tomar
Source: check_circle
Crossref

Enhancing affinity of neutralizing SARS-CoV-2 nanobody through facile structure-guided mutations in CDRs

2024-05-13 | Preprint
DOI: 10.1101/2024.05.13.593833
Contributors: Vishakha Singh; Mandar Bhutkar; Shweta Choudhary; Sanketkumar Nehul; Rajesh Kumar; Jitin Singla; Pravindra Kumar; Shailly Tomar
Source: check_circle
Crossref

Mechanistic and thermodynamic characterization of antiviral inhibitors targeting nucleocapsid N-terminal domain of SARS-CoV-2

Archives of Biochemistry and Biophysics
2023-12 | Journal article
DOI: 10.1016/j.abb.2023.109820
Contributors: Preeti Dhaka; Ankur Singh; Shweta Choudhary; Rama Krishna Peddinti; Pravindra Kumar; Gaurav Kumar Sharma; Shailly Tomar
Source: check_circle
Crossref

Repurposing efavirenz, the HIV antiretroviral drug for Chikungunya virus infection

2023-09-29 | Preprint
DOI: 10.1101/2023.09.29.560149
Contributors: Sanketkumar Nehul; Ruchi Rani; Prasan Kumar Panda; Pravindra Kumar; Shailly Tomar
Source: check_circle
Crossref

Revealing and evaluation of antivirals targeting multiple druggable sites of RdRp complex in SARS-CoV-2

2023-07-24 | Preprint
DOI: 10.1101/2023.07.24.550324
Contributors: Ruchi Rani; Sanketkumar Nehul; Shweta Choudhary; Anushka Upadhyay; Gaurav Kumar Sharma; Pravindra Kumar; Shailly Tomar
Source: check_circle
Crossref

Unraveling antiviral efficacy of multifunctional immunomodulatory triterpenoids against SARS-COV-2 targeting main protease and papain-like protease

2023-06-26 | Preprint
DOI: 10.1101/2023.06.24.546363
Contributors: Shweta Choudhary; Sanketkumar Nehul; Ankur Singh; Prasan Kumar Panda; Pravindra Kumar; Gaurav Kumar Sharma; Shailly Tomar
Source: check_circle
Crossref

In Silico Guided Drug Repurposing to Combat SARS-CoV-2 by Targeting Mpro, the Key Virus Specific Protease

2023-02-27 | Preprint
DOI: 10.26434/chemrxiv-2023-qf6rb-v2
Contributors: Ankur Singh; Ruchi Rani; Akshay Pareek; Shailly Tomar; Pravindra Kumar
Source: check_circle
Crossref

Cellular uptake of metal oxide-based nanocomposites and targeting of chikungunya virus replication protein nsP3

2023-02-20 | Preprint
DOI: 10.26434/chemrxiv-2023-43349
Contributors: Shailly Tomar; Pooja Bhatia; Vedita Anand Singh; Ruchi Rani; Mala Nath
Source: check_circle
Crossref

Chimeric chikungunya virus-like particles with surface exposed SARS-CoV-2 RBD elicits potent immunogenic responses in mice

2023-01-29 | Preprint
DOI: 10.1101/2023.01.29.526074
Contributors: Vedita Anand Singh; Sanket Nehul; Chandra Shekhar Kumar; Manidipa Banerjee; Pravindra Kumar; Gaurav Sharma; Shailly Tomar
Source: check_circle
Crossref

Multi-target direct-acting SARS-CoV-2 antivirals against the nucleotide-binding pockets of virus-specific proteins

Virology
2022-12 | Journal article
DOI: 10.1016/j.virol.2022.08.008
Contributors: Ruchi Rani; Siwen Long; Akshay Pareek; Preeti Dhaka; Ankur Singh; Pravindra Kumar; Gerald McInerney; Shailly Tomar
Source: check_circle
Crossref

MD simulation and MM/PBSA identifies phytochemicals as bifunctional inhibitors of SARS-CoV-2

Journal of Biomolecular Structure and Dynamics
2022-12-12 | Journal article | Author
DOI: 10.1080/07391102.2021.1969285
Part of ISSN: 0739-1102
Part of ISSN: 1538-0254
Contributors: Monica Sharma; Jai Krishna Mahto; Preeti Dhaka; Neetu Neetu; Shailly Tomar; Pravindra Kumar
Source: Self-asserted source
Shailly Tomar
grade
Preferred source (of 2)‎

Crystal structure and activity profiling of deubiquitinating inhibitors-bound to SARS-CoV-2 papain like protease revealed new allosteric sites for antiviral therapies

2022-11-11 | Preprint
DOI: 10.1101/2022.11.11.516107
Contributors: Shweta Choudhary; Sanketkumar Nehul; K Amith Kumar; Swati Sharma; Ruchi Rani; Ankita Saha; Gaurav Kumar Sharma; Shailly Tomar; Pravindra Kumar
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Crossref

Targeting the host protein G3BP1 for the discovery of novel antiviral inhibitors against Chikungunya virus

2022-11-11 | Preprint
DOI: 10.1101/2022.11.11.516135
Contributors: Supreeti Mahajan; Ravi Kumar; Ankur Singh; Akshay Pareek; Pravindra Kumar; Shailly Tomar
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Crossref

Alphavirus antivirals targeting RNA‐dependent RNA polymerase domain of nsP4 divulged using surface plasmon resonance

The FEBS Journal
2022-08 | Journal article | Author
DOI: 10.1111/febs.16397
Part of ISSN: 1742-464X
Part of ISSN: 1742-4658
Contributors: Akshay Pareek; Ravi Kumar; Rajat Mudgal; Neetu Neetu; Monica Sharma; Pravindra Kumar; Shailly Tomar
Source: Self-asserted source
Shailly Tomar
grade
Preferred source (of 2)‎

Computational guided identification of novel potent inhibitors of N-terminal domain of nucleocapsid protein of severe acute respiratory syndrome coronavirus 2

Journal of Biomolecular Structure and Dynamics
2022-06-13 | Journal article
DOI: 10.1080/07391102.2020.1852968
Contributors: Poonam Dhankhar; Vikram Dalal; Vishakha Singh; Shailly Tomar; Pravindra Kumar
Source: check_circle
Crossref

Selective Estrogen Receptor Modulators Limit Alphavirus Infection by Targeting the Viral Capping Enzyme nsP1

Antimicrobial Agents and Chemotherapy
2022-03-15 | Journal article | Author
DOI: 10.1128/aac.01943-21
Part of ISSN: 0066-4804
Part of ISSN: 1098-6596
Contributors: Rajat Mudgal; Chandrima Bharadwaj; Aakriti Dubey; Shweta Choudhary; Perumal Nagarajan; Megha Aggarwal; Yashika Ratra; Soumen Basak; Shailly Tomar
Source: Self-asserted source
Shailly Tomar
grade
Preferred source (of 2)‎

Mechanistic and thermodynamic characterization of antivirals targeting druggable pocket of SARS-CoV-2 nucleocapsid

2022-03-14 | Preprint
DOI: 10.1101/2022.03.12.484092
Contributors: Preeti Dhaka; Ankur Singh; Shweta Choudhary; Rama Krishna Peddinti; Pravindra Kumar; Gaurav Kumar Sharma; Shailly Tomar
Source: check_circle
Crossref

Emerging SARS-CoV-2 Variants: Genetic Variability and Clinical Implications

Current Microbiology
2022-01 | Journal article
DOI: 10.1007/s00284-021-02724-1
Contributors: Aakriti Dubey; Shweta Choudhary; Pravindra Kumar; Shailly Tomar
Source: check_circle
Crossref

Molecular insights into substrate recognition and catalysis by phthalate dioxygenase from Comamonas testosteroni

Journal of Biological Chemistry
2021-12 | Journal article
DOI: 10.1016/j.jbc.2021.101416
Part of ISSN: 0021-9258
Contributors: Jai Krishna Mahto; Neetu Neetu; Bhairavnath Waghmode; Eugene Kuatsjah; Monica Sharma; Debabrata Sircar; Ashwani Kumar Sharma; Shailly Tomar; Lindsay D. Eltis; Pravindra Kumar
Source: Self-asserted source
Shailly Tomar

Characterization of recombinant pumpkin 2S albumin and mutation studies to unravel potential DNA/RNA binding site

Biochemical and Biophysical Research Communications
2021-11 | Journal article | Author
DOI: 10.1016/j.bbrc.2021.09.076
Part of ISSN: 0006-291X
Contributors: Brajesh Kumar Savita; Dr. Vikram Dalal; Shailly Tomar; Deena Nath Gupta; Neeladrisingha Das; Shailly Tomar; Pravindra Kumar; Partha Roy; Ashwani Kumar Sharma
Source: Self-asserted source
Shailly Tomar
grade
Preferred source (of 2)‎

Deciphering the enigma of missing DNA binding domain of LacI family transcription factors

Archives of Biochemistry and Biophysics
2021-11 | Journal article | Author
DOI: 10.1016/j.abb.2021.109060
Part of ISSN: 0003-9861
Contributors: Neetu Neetu; Madhusudhanarao Katiki; Jai Krishna Mahto; Monica Sharma; Anoop Narayanan; Sudipa Maity; Shailly Tomar; Kiran Ambatipudi; Ashwani Kumar Sharma; Dinesh Yernool et al.
Source: Self-asserted source
Shailly Tomar
grade
Preferred source (of 2)‎

Chikungunya virus titration, detection and diagnosis using N-Acetylglucosamine (GlcNAc) specific lectin based virus capture assay

Virus Research
2021-09 | Journal article
DOI: 10.1016/j.virusres.2021.198493
Part of ISSN: 0168-1702
Contributors: Shweta Choudhary; Neetu Neetu; Vedita Anand Singh; Pravindra Kumar; Madhulika Chaudhary; Shailly Tomar
Source: Self-asserted source
Shailly Tomar

Identification and evaluation of antiviral potential of thymoquinone, a natural compound targeting Chikungunya virus capsid protein

Virology
2021-09 | Journal article
DOI: 10.1016/j.virol.2021.05.013
Part of ISSN: 0042-6822
Contributors: Ravi Kumar; Sanketkumar Nehul; Ankur Singh; Shailly Tomar
Source: Self-asserted source
Shailly Tomar

Multifunctional inhibitors of SARS-CoV-2 by MM/PBSA, essential dynamics, and molecular dynamic investigations

Journal of Molecular Graphics and Modelling
2021-09 | Journal article
DOI: 10.1016/j.jmgm.2021.107969
Part of ISSN: 1093-3263
Contributors: Amith Kumar; Monica Sharma; Vikram Dalal; Vishakha Singh; Shailly Tomar; Pravindra Kumar
Source: Self-asserted source
Shailly Tomar
grade
Preferred source (of 2)‎

Selective estrogen receptor modulators limit alphavirus infection by targeting the viral capping enzyme nsP1

2021-08-20 | Preprint
DOI: 10.1101/2021.08.19.457046
Contributors: Rajat Mudgal; Chandrima Bharadwaj; Aakriti Dubey; Shweta Choudhary; Perumal Nagarajan; Megha Aggarwal; Yashika Ratra; Soumen Basak; Shailly Tomar
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Crossref

SARS‐CoV‐2, the pandemic coronavirus: Molecular and structural insights

Journal of Basic Microbiology
2021-03 | Journal article
DOI: 10.1002/jobm.202000537
Part of ISSN: 0233-111X
Part of ISSN: 1521-4028
Contributors: Swapnil B. Kadam; Geetika S. Sukhramani; Pratibha Bishnoi; Anupama A. Pable; Dr. Vitthal T. Barvkar
Source: Self-asserted source
Shailly Tomar
grade
Preferred source (of 2)‎

Evolutionary and codon usage preference insights into spike glycoprotein of SARS-CoV-2

Briefings in Bioinformatics
2021-03-22 | Journal article
DOI: 10.1093/bib/bbaa383
Part of ISSN: 1467-5463
Part of ISSN: 1477-4054
Contributors: Yashpal Singh Malik; Mohd Ikram Ansari; Jobin Jose Kattoor; Rahul Kaushik; Shubhankar Sircar; Anbazhagan Subbaiyan; Ruchi Tiwari; Kuldeep Dhama; Souvik Ghosh; Shailly Tomar et al.
Source: Self-asserted source
Shailly Tomar

Characterization of dye-decolorizing peroxidase from Bacillus subtilis

Archives of Biochemistry and Biophysics
2020-10 | Journal article
DOI: 10.1016/j.abb.2020.108590
Part of ISSN: 0003-9861
Contributors: Poonam Dhankhar; Vikram Dalal; Jai Krishna Mahto; Bhola Ram Gurjar; Shailly Tomar; Ashwani Kumar Sharma; Pravindra Kumar
Source: Self-asserted source
Shailly Tomar

Identification of SARS-CoV-2 Cell Entry Inhibitors by Drug Repurposing Using in Silico Structure-Based Virtual Screening Approach

2020-04-15 | Preprint
DOI: 10.26434/chemrxiv.12005988.v2
Contributors: Shweta Choudhary; Yashpal S. Malik; Shailly Tomar
Source: check_circle
Crossref

In Silico Guided Drug Repurposing to Combat SARS-CoV-2 by Targeting Mpro, the Key Virus Specific Protease

2020-03-26 | Preprint
DOI: 10.26434/chemrxiv.12030345.v1
Contributors: Ruchi Rani; Ankur Singh; Akshay Pareek; Shailly Tomar
Source: check_circle
Crossref

Identification of SARS-CoV-2 Cell Entry Inhibitors by Drug Repurposing Using in Silico Structure-Based Virtual Screening Approach

2020-03-20 | Preprint
DOI: 10.26434/chemrxiv.12005988.v1
Contributors: Shweta Choudhary; Yashpal S. Malik; Shailly Tomar
Source: check_circle
Crossref

Inhibition of Chikungunya virus by an adenosine analog targeting the SAM‐dependent nsP1 methyltransferase

FEBS Letters
2020-02 | Journal article
DOI: 10.1002/1873-3468.13642
Contributors: Rajat Mudgal; Supreeti Mahajan; Shailly Tomar
Source: check_circle
Crossref

Peer review (41 reviews for 15 publications/grants)

Review activity for ACS infectious diseases. (3)
Review activity for ACS omega. (1)
Review activity for Antiviral research. (1)
Review activity for Archives of virology. (1)
Review activity for Biochemical and biophysical research communications. (3)
Review activity for Biochemistry. (2)
Review activity for Biochimica et biophysica acta. Molecular cell research (1)
Review activity for Communications biology. (2)
Review activity for International journal of biological macromolecules. (2)
Review activity for iScience. (1)
Review activity for Microbial pathogenesis. (1)
Review activity for Nature communications (1)
Review activity for Virology. (20)
Review activity for Virus research (1)
Review activity for Virusdisease. (1)
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