Personal information

Immunity, inflammation, Macrophages, Microbiome, Skin, Gut, HS, IBD
Ireland

Biography

Assistant Prof in Anatomy in School of Medicine, Trinity College Dublin.
Interested in inflammation, immunology the microbiome and diseases of the skin and gut.

Previous:
- AbbVie Newman Fellow in Dermatology, Charles Insitute of Dermatology, UCD, Ireland.
Investigating innate immune mechanisms in the pathogenesis of skin disorders including hidradenitis suppurativa (HS).
- Postdoctoral research in immune homeostasis in the gut. Based in the Prof Fiona Powrie Laboratory in the Kennedy Institute of Rheumatology, Oxford UK. Bryan Warren Junior Research Fellowship in Linacre College, Oxford.
PhD thesis on microRNA influence of infection and gut microbiome phenotypes in colitis in the Corr and O'Neill labs, Trinity College Dublin.

Activities

Employment (5)

Trinity College Dublin: Dublin, IE

2022-08-08 to present | Assistant Professor of Anatomy (Medicine)
Employment
Source: Self-asserted source
Daniel GW Johnston

University College Dublin: Dublin, IE

2020-03-01 to 2022-08-08 | AbbVie Newman Fellow in Dermatology (Charles Institute of Dermatology)
Employment
Source: Self-asserted source
Daniel GW Johnston

University of Oxford: Oxford, Oxfordshire, GB

2017-09-25 to 2020-03-01 | Postdoctoral Fellow (Kennedy Institute of Rheumatology)
Employment
Source: Self-asserted source
Daniel GW Johnston

University of Dublin Trinity College: Dublin, IE

2017-03-01 to 2017-06-01 | Research Assistant (Biochemistry and Immunology)
Employment
Source: Self-asserted source
Daniel GW Johnston

University of Dublin Trinity College: Dublin, IE

2011-06-01 to 2011-09-01 | Research Assistant (Trinity College Institute of Neuroscience)
Employment
Source: Self-asserted source
Daniel GW Johnston

Education and qualifications (2)

The University of Dublin Trinity College: Dublin, IE

2013-03-01 to 2017-11-01 | PhD in Immunology (Biochemistry and Immunology)
Education
Source: Self-asserted source
Daniel GW Johnston

University of Dublin Trinity College: Dublin, IE

2008-09-01 to 2012-06-01 | B.A (Mod) Biochemistry with Immunology
Education
Source: Self-asserted source
Daniel GW Johnston

Professional activities (5)

Irish Society for Immunology: Dublin, IE

2021-01 to present | Chair of ECR committee
Service
Source: Self-asserted source
Daniel GW Johnston

British Society for Immunology: Oxford, GB

2017-12-01 to present
Membership
Source: Self-asserted source
Daniel GW Johnston

Biochemical Society: London, London, GB

2017-12-01 to present
Membership
Source: Self-asserted source
Daniel GW Johnston

University College Dublin: Dublin, IE

2022-09-01 to 2025-09-01 | Visiting Assistant Prof (Charles Institute of Dermatology )
Invited position
Source: Self-asserted source
Daniel GW Johnston

Linacre College, University of Oxford: Oxford, GB

2017-09-01 | Bryan Warren Junior Research Fellowship
Distinction
Source: Self-asserted source
Daniel GW Johnston

Funding (7)

Functional analysis of hidradenitis suppurativa inflammasome protein mutations in keratinocytes

2024-04 to 2025-04 | Grant
British Skin Foundation (London, GB)
Source: Self-asserted source
Daniel GW Johnston

Functional analysis of inflammasome protein mutations n the inflammatory skin disease hidradenitis suppurativa

2023-02 to present | Grant
City of Dublin Skin and Cancer Hospital Charity (Dublin, Dublin, IE)
Source: Self-asserted source
Daniel GW Johnston

HRB-Fulbright HealthImpact award

2021-12 to 2022-06 | Award
Health Research Board (Dublin, IE)
Source: Self-asserted source
Daniel GW Johnston

An analysis of inflammasome activity in the skin and blood of patients with hidradenitis suppurativa

2020-12 to present | Grant
British Skin Foundation (London, GB)
GRANT_NUMBER:

024/BSFSG/20

Source: Self-asserted source
Daniel GW Johnston

Danger in the skin: novel immune activators in Hidradenitis Suppurativa

2020-08 to 2022-08 | Grant
University College Dublin (Dublin, IE)
Source: Self-asserted source
Daniel GW Johnston

AbbVie Newman Fellowship in Dermatology

2020-03 to 2022-03 | Award
AbbVie/University College Dublin (Dublin, IE)
Source: Self-asserted source
Daniel GW Johnston

Bryan Warren Junior Research Fellowship

2017-10 to 2020-10 | Award
Linacre College, University of Oxford (Oxford, GB)
Source: Self-asserted source
Daniel GW Johnston

Works (20)

Inflammasomes: emerging therapeutic targets in hidradenitis suppurativa?

British Journal of Dermatology
2024-10-17 | Journal article
Contributors: Ciara Campbell; Jay M Mayatra; Ashish J Neve; Jean M Fletcher; Daniel G W Johnston
Source: check_circle
Crossref

Cell‐free DNA is elevated in the serum of patients with hidradenitis suppurativa

The Journal of Dermatology
2023-02 | Journal article
Contributors: Daniel G. W. Johnston; Roisin Hambly; Niamh Kearney; Desmond J. Tobin; Brian Kirby
Source: check_circle
Crossref

ANALYSIS OF INFLAMMASOME PROTEIN EXPRESSION IN HIDRADENITIS SUPPURATIVA PATIENT TISSUE

IRISH JOURNAL OF MEDICAL SCIENCE
2022 | Conference paper
Contributors: O'Donohoe, S; Leahy, C; Johnston, DGW; Tobin, DJ
Source: Self-asserted source
Daniel GW Johnston

Can the collapse of the human scalp hair follicle pigmentary unit with age (canities) provide insight into how melanocyte death could be induced in melanoma?

BRITISH JOURNAL OF DERMATOLOGY
2022 | Conference paper
Contributors: Buruno, H; Johnston, D; Tobin, D
Source: Self-asserted source
Daniel GW Johnston

A preliminary study of soluble CD14 levels in the serum of patients with hidradenitis suppurativa as a marker of “leaky gut” [version 1; peer review: 2 not approved]

2022-10-25 | Journal article
Part of ISSN: 2515-4826
Contributors: Daniel G W Johnston; Roisin Hambly; Niamh Kearney; Desmond J Tobin; Brian Kirby; Hambly Roisin; Hambly Roisin; Hambly Roisin; Johnston Daniel G W; Johnston Daniel G W et al.
Source: check_circle
HRB Open Research

CAN THE COLLAPSE OF THE SCALP HAIR FOLLICLE PIGMENTARY UNIT WITH AGE (CANITIES) PROVIDE INSIGHTS INTO HOW MELANOCYTE DEATH COULD BE INDUCED IN MELANOMA?

IRISH JOURNAL OF MEDICAL SCIENCE
2021 | Conference paper
Contributors: Buruno, H; Johnston, D; Tobin, DJ
Source: Self-asserted source
Daniel GW Johnston

Hidradenitis suppurativa: A folliculotropic disease of innate immune barrier dysfunction?

Experimental Dermatology
2021-10 | Journal article
Contributors: Daniel G.W. Johnston; Brian Kirby; Desmond J. Tobin
Source: check_circle
Crossref

Mycobacterium tuberculosis Limits Host Glycolysis and IL-1β by Restriction of PFK-M via MicroRNA-21

Cell Reports
2020-01-07 | Journal article
Part of ISSN: 2211-1247
Source: Self-asserted source
Daniel GW Johnston
grade
Preferred source (of 3)‎

Alfred I. Tauber, Immunity: The Evolution of an Idea (New York: Oxford University Press, 2017), 328 pages. ISBN: 9780190651244. Hardcover: $78.00, Paperback $39.95.

Politics and the Life Sciences
2019 | Journal article
Contributors: Daniel Johnston
Source: check_circle
Crossref

The Short Chain Fatty Acid Butyrate Imprints an Antimicrobial Program in Macrophages.

Immunity
2019-01 | Journal article
Contributors: Schulthess J; Pandey S; Capitani M; Rue-Albrecht KC; Arnold I; Franchini F; Chomka A; Ilott NE; Johnston DGW; Pires E et al.
Source: Self-asserted source
Daniel GW Johnston via Europe PubMed Central

Loss of microRNA-21 Influences the Gut Microbiota Causing Reduced Susceptibility in a Murine Model of Colitis.

Journal of Crohn's & colitis
2018-03 | Journal article
Contributors: Johnston DGW; Williams MA; Thaiss CA; Cabrera-Rubio R; Raverdeau M; McEntee C; Cotter PD; Elinav E; O'Neill LAJ; Corr SC
Source: Self-asserted source
Daniel GW Johnston via Europe PubMed Central
grade
Preferred source (of 2)‎

A role for microRNA-21 in the regulation of gastrointestinal health and disease

2017 | Dissertation/Thesis
Contributors: Johnston, Daniel
Source: Self-asserted source
Daniel GW Johnston

MicroRNA-21 Limits Uptake of Listeria monocytogenes by Macrophages to Reduce the Intracellular Niche and Control Infection.

Frontiers in cellular and infection microbiology
2017 | Journal article
Source: Self-asserted source
Daniel GW Johnston via Europe PubMed Central
grade
Preferred source (of 2)‎

Su1893 Modulation of Intestinal Homeostasis and Microbial Activities by miR-21 in the Pathogenesis of Inflammatory Bowel Disease

Gastroenterology
2016 | Journal article
Contributors: Johnston, Daniel; O'Neill, Luke; Corr, Sinéad
Source: Self-asserted source
Daniel GW Johnston

Toll-Like Receptor Signalling and the Control of Intestinal Barrier Function.

2016 | Journal article
Contributors: Johnston DG; Corr SC
Source: Self-asserted source
Daniel GW Johnston via Europe PubMed Central
grade
Preferred source (of 2)‎

Erratum: Pyruvate kinase m2 regulates hif-1α activity and IL-1β induction and is a critical determinant of the warburg effect in lps-activated macrophages (Cell Metabolism (2015) 21 (65-80))

Cell Metabolism
2015 | Journal article
EID:

2-s2.0-84922860779

Contributors: Palsson-Mcdermott, E.M.; Curtis, A.M.; Goel, G.; Lauterbach, M.A.R.; Sheedy, F.J.; Gleeson, L.E.; Van Den Bosch, M.W.M.; Quinn, S.R.; Domingo-Fernandez, R.; Johnston, D.G.W. et al.
Source: Self-asserted source
Daniel GW Johnston via Scopus - Elsevier

Pyruvate kinase M2 regulates Hif-1α activity and IL-1β induction and is a critical determinant of the warburg effect in LPS-activated macrophages.

2015-01 | Journal article
Contributors: Palsson-McDermott EM; Curtis AM; Goel G; Lauterbach MA; Sheedy FJ; Gleeson LE; van den Bosch MW; Quinn SR; Domingo-Fernandez R; Johnston DG et al.
Source: Self-asserted source
Daniel GW Johnston via Europe PubMed Central
grade
Preferred source (of 2)‎

MyD88 adaptor-like (Mal) regulates intestinal homeostasis and colitis-associated colorectal cancer in mice.

2014-05 | Journal article
Contributors: Aviello G; Corr SC; Johnston DG; O'Neill LA; Fallon PG
Source: Self-asserted source
Daniel GW Johnston via Europe PubMed Central
grade
Preferred source (of 2)‎

Differential role of Dok1 and Dok2 in TLR2-induced inflammatory signaling in glia.

2013-09 | Journal article
Contributors: Downer EJ; Johnston DG; Lynch MA
Source: Self-asserted source
Daniel GW Johnston via Europe PubMed Central
grade
Preferred source (of 2)‎

MicroRNA-21 regulates phagocytic responses during infection with Listeria monocytogenes

Journal article
Contributors: Johnston, Daniel GW; O’Neill, Luke AJ; Corr, Sinéad C
Source: Self-asserted source
Daniel GW Johnston

Peer review (2 reviews for 2 publications/grants)

Review activity for Clinical and experimental dermatology (1)
Review activity for Stem cell research & therapy. (1)