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Employment (5)

Zhujiang Hospital: Guangzhou, Guangdong, CN

2005-10 to present | Professor (Pathology)
Employment
Source: Self-asserted source
Linlang Guo

Zhujiang Hospital: Guangzhou, Guangdong, CN

1998-09 to 2005-09 | Associate professor (Pathology)
Employment
Source: Self-asserted source
Linlang Guo

Zhujiang Hospital: Guangzhou, Guangdong, CN

1992-07 to 1998-08 | Lecturer (Pathology)
Employment
Source: Self-asserted source
Linlang Guo

Zhujiang Hospital: Guangzhou, Guangdong, CN

1991-07 to 1992-06 | Teaching assistant (Pathology)
Employment
Source: Self-asserted source
Linlang Guo

First Affiliated Hospital of Bengbu Medical College: Bengbu, CN

1986-07 to 1988-08 | Teaching assistant (Pathology)
Employment
Source: Self-asserted source
Linlang Guo

Education and qualifications (5)

Southern Medical University: Guangzhou, Guangdong, CN

2006-09-01 to 2009-07 | PhD (Pathology)
Education
Source: Self-asserted source
Linlang Guo

University of California Davis Comprehensive Cancer Center: Sacramento, CA, US

2003-10 to 2005-09 | Visiting scholar
Qualification
Source: Self-asserted source
Linlang Guo

University of California Davis Comprehensive Cancer Center: Sacramento, CA, US

1999-11 to 2001-07 | Visiting scholar
Qualification
Source: Self-asserted source
Linlang Guo

Sun Yat-sen University: Guangzhou, Guangdong, CN

1988-09 to 1991-07 | Master (Pathology)
Education
Source: Self-asserted source
Linlang Guo

Bengbu Medical College: Bengbu, Anhui, CN

1981-09 to 1986-06 | Bachelor (Clinical Medicine)
Education
Source: Self-asserted source
Linlang Guo

Works (43)

Identifying CDC7 as a synergistic target of chemotherapy in resistant small-cell lung cancer via CRISPR/Cas9 screening

Cell Death Discovery
2023-02-02 | Journal article
DOI: 10.1038/s41420-023-01315-2
Contributors: Ling Deng; Li Yang; Shuhan Zhu; Man Li; Yu Wang; Xiaolong Cao; Qiongyao Wang; Linlang Guo
Source: check_circle
Crossref

Bioinformatic Analysis of Prognostic Value of SNTG2 with Immune Implications in Lung Adenocarcinoma

International Journal of General Medicine
2022-05 | Journal article
DOI: 10.2147/IJGM.S355393
Contributors: Jian Zhou; Yang Wen; Xiangtian Chen; Linlang Guo
Source: check_circle
Crossref

Long noncoding RNA Linc00173 modulates glucose metabolism and multidrug chemoresistance in small cell lung cancer: Potential molecular panel for targeted therapy

Molecular Therapy
2021-11 | Journal article
DOI: 10.1016/j.ymthe.2021.11.003
Part of ISSN: 1525-0016
Source: Self-asserted source
Linlang Guo

Inhibition of lncRNA KCNQ1OT1 Improves Apoptosis and Chemotherapy Drug Response in Small Cell Lung Cancer by TGF-β1 Mediated Epithelial-to-Mesenchymal Transition

Cancer Research and Treatment
2021-10-15 | Journal article
DOI: 10.4143/crt.2020.1208
Part of ISSN: 1598-2998
Part of ISSN: 2005-9256
Source: Self-asserted source
Linlang Guo

EPHA5 mutation predicts the durable clinical benefit of immune checkpoint inhibitors in patients with lung adenocarcinoma

Cancer Gene Therapy
2021-08-06 | Journal article
DOI: 10.1038/s41417-020-0207-6
Contributors: Weimei Huang; Anqi Lin; Peng Luo; Yuchen Liu; Wentao Xu; Weiliang Zhu; Ting Wei; Qingwen Lyu; Linlang Guo; Jian Zhang
Source: check_circle
Crossref

Decreased TMEM40 expression is associated with malignant behavior of cutaneous squamous cell carcinoma and inhibits tumor progression

Oncology Letters
2021-06-15 | Journal article
DOI: 10.3892/ol.2021.12867
Part of ISSN: 1792-1074
Part of ISSN: 1792-1082
Source: Self-asserted source
Linlang Guo

MGA Mutation as a Novel Biomarker for Immune Checkpoint Therapies in Non-Squamous Non-Small Cell Lung Cancer

Frontiers in Pharmacology
2021-04-13 | Journal article
DOI: 10.3389/fphar.2021.625593
Part of ISSN: 1663-9812
Source: Self-asserted source
Linlang Guo

ATM mutations as an independent prognostic factor and potential biomarker for immune checkpoint therapy in endometrial cancer

Pathology - Research and Practice
2020-08 | Journal article
DOI: 10.1016/j.prp.2020.153032
Part of ISSN: 0344-0338
Source: Self-asserted source
Linlang Guo

Difference of background in research and clinical practice between USA and China

Journal of Thoracic Disease
2020-07 | Journal article
DOI: 10.21037/jtd.2020.04.07
Part of ISSN: 2072-1439
Part of ISSN: 2077-6624
Source: Self-asserted source
Linlang Guo

Circular RNA cESRP1 sensitises small cell lung cancer cells to chemotherapy by sponging miR-93-5p to inhibit TGF-β signalling

Cell Death & Differentiation
2020-05 | Journal article
DOI: 10.1038/s41418-019-0455-x
Part of ISSN: 1350-9047
Part of ISSN: 1476-5403
Source: Self-asserted source
Linlang Guo

DNAH10 mutation correlates with cisplatin sensitivity and tumor mutation burden in small-cell lung cancer

Aging
2020-01-20 | Journal article
DOI: 10.18632/aging.102683
Part of ISSN: 1945-4589
Source: Self-asserted source
Linlang Guo

Linc00173 promotes chemoresistance and progression of small cell lung cancer by sponging miR-218 to regulate Etk expression

Oncogene
2020-01-09 | Journal article
DOI: 10.1038/s41388-019-0984-2
Part of ISSN: 0950-9232
Part of ISSN: 1476-5594
Source: Self-asserted source
Linlang Guo

Integrated high-throughput analysis identifies super enhancers associated with chemoresistance in SCLC

BMC Medical Genomics
2019-12 | Journal article
DOI: 10.1186/s12920-019-0520-9
Contributors: Jiarong Bao; Man Li; Shumei Liang; Yunchu Yang; Jingfang Wu; Qingqing Zou; Shun Fang; Size Chen; Linlang Guo
Source: check_circle
Crossref

MYCN-mediated regulation of the HES1 promoter enhances the chemoresistance of small-cell lung cancer by modulating apoptosis.

American journal of cancer research
2019-09-01 | Journal article
PMID: 31598396
PMC: PMC6780666
Source: Self-asserted source
Linlang Guo

HOTAIR contributes to chemoresistance by activating NF-κB signaling in small-cell lung cancer.

International journal of clinical and experimental pathology
2019-08-01 | Journal article
PMID: 31934137
PMC: PMC6949698
Source: Self-asserted source
Linlang Guo

Long noncoding RNA PCAT6 inhibits colon cancer cell apoptosis by regulating anti-apoptotic protein ARC expression via EZH2

Cell Cycle
2019-01-02 | Journal article
DOI: 10.1080/15384101.2018.1558872
Part of ISSN: 1538-4101
Part of ISSN: 1551-4005
Source: Self-asserted source
Linlang Guo

miR-216a-5p inhibits malignant progression in small cell lung cancer: involvement of the Bcl-2 family proteins

Cancer Management and Research
2018-10 | Journal article
DOI: 10.2147/cmar.s178380
Part of ISSN: 1179-1322
Source: Self-asserted source
Linlang Guo

Long non-coding RNA HOTTIP promotes BCL-2 expression and induces chemoresistance in small cell lung cancer by sponging miR-216a

Cell Death & Disease
2018-02 | Journal article
DOI: 10.1038/s41419-017-0113-5
Part of ISSN: 2041-4889
Source: Self-asserted source
Linlang Guo

Etk Interaction with PFKFB4 Modulates Chemoresistance of Small-cell Lung Cancer by Regulating Autophagy

Clinical Cancer Research
2018-02-15 | Journal article
DOI: 10.1158/1078-0432.ccr-17-1475
Part of ISSN: 1078-0432
Part of ISSN: 1557-3265
Source: Self-asserted source
Linlang Guo

A long non-coding RNA HOTTIP expression is associated with disease progression and predicts outcome in small cell lung cancer patients

Molecular Cancer
2017-12 | Journal article
DOI: 10.1186/s12943-017-0729-1
Part of ISSN: 1476-4598
Source: Self-asserted source
Linlang Guo

Long non-coding RNA TUG1 is involved in cell growth and chemoresistance of small cell lung cancer by regulating LIMK2b via EZH2

Molecular Cancer
2017-12 | Journal article
DOI: 10.1186/s12943-016-0575-6
Part of ISSN: 1476-4598
Source: Self-asserted source
Linlang Guo
grade
Preferred source (of 2)‎

The role and potential mechanisms of long non-coding RNA in small cell lung cancer

Journal of Thoracic Disease
2017-10 | Journal article
DOI: 10.21037/jtd.2017.09.70
Part of ISSN: 2072-1439
Part of ISSN: 2077-6624
Source: Self-asserted source
Linlang Guo

Overexpression of Rictor protein in colorectal cancer is correlated with tumor progression and prognosis

Oncology Letters
2017-09-14 | Journal article
DOI: 10.3892/ol.2017.6936
Part of ISSN: 1792-1074
Part of ISSN: 1792-1082
Source: Self-asserted source
Linlang Guo

Sensitive impedimetric DNA biosensor based on (Nb,V) codoped TiO2 for breast cancer susceptible gene detection

Materials Science and Engineering: C
2017-08 | Journal article
DOI: 10.1016/j.msec.2017.03.260
Part of ISSN: 0928-4931
Source: Self-asserted source
Linlang Guo

Targeted radionuclide therapy for lung cancer with iodine-131-labeled peptide in a nude-mouse model

Anti-Cancer Drugs
2017-06 | Journal article
DOI: 10.1097/cad.0000000000000481
Part of ISSN: 0959-4973
Source: Self-asserted source
Linlang Guo

Identification of DJ-1 as a contributor to multidrug resistance in human small-cell lung cancer using proteomic analysis

International Journal of Experimental Pathology
2017-04 | Journal article
DOI: 10.1111/iep.12221
Part of ISSN: 0959-9673
Source: Self-asserted source
Linlang Guo
grade
Preferred source (of 2)‎

miR-495 promotes the chemoresistance of SCLC through the epithelial-mesenchymal transition via Etk/BMX.

American journal of cancer research
2017-03-01 | Journal article
PMID: 28401017
PMC: PMC5384991
Source: Self-asserted source
Linlang Guo

EPHA3 regulates the multidrug resistance of small cell lung cancer via the PI3K/BMX/STAT3 signaling pathway

Tumor Biology
2016-09 | Journal article
DOI: 10.1007/s13277-016-5048-4
Part of ISSN: 1010-4283
Part of ISSN: 1423-0380
Source: Self-asserted source
Linlang Guo

WW domain binding protein 5 induces multidrug resistance of small cell lung cancer under the regulation of miR-335 through the Hippo pathway

British Journal of Cancer
2016-07 | Journal article
DOI: 10.1038/bjc.2016.186
Part of ISSN: 0007-0920
Part of ISSN: 1532-1827
Source: Self-asserted source
Linlang Guo

A Multi-Step miRNA-mRNA Regulatory Network Construction Approach Identifies Gene Signatures Associated with Endometrioid Endometrial Carcinoma

Genes
2016-06-02 | Journal article
DOI: 10.3390/genes7060026
Part of ISSN: 2073-4425
Source: Self-asserted source
Linlang Guo

An ANCCA/PRO2000-miR-520a-E2F2 regulatory loop as a driving force for the development of hepatocellular carcinoma

Oncogenesis
2016-05 | Journal article
DOI: 10.1038/oncsis.2016.22
Part of ISSN: 2157-9024
Source: Self-asserted source
Linlang Guo

Long noncoding RNA-HOTAIR affects chemoresistance by regulating HOXA1 methylation in small cell lung cancer cells

Laboratory Investigation
2016-01 | Journal article
DOI: 10.1038/labinvest.2015.123
Part of ISSN: 0023-6837
Part of ISSN: 1530-0307
Source: Self-asserted source
Linlang Guo

Upregulation of the inwardly rectifying potassium channel Kir2.1 (KCNJ2) modulates multidrug resistance of small-cell lung cancer under the regulation of miR-7 and the Ras/MAPK pathway

Molecular Cancer
2015-12 | Journal article
DOI: 10.1186/s12943-015-0298-0
Part of ISSN: 1476-4598
Source: Self-asserted source
Linlang Guo

miR-7 modulates chemoresistance of small cell lung cancer by repressing MRP1/ABCC1

International Journal of Experimental Pathology
2015-08 | Journal article
DOI: 10.1111/iep.12131
Part of ISSN: 0959-9673
Source: Self-asserted source
Linlang Guo

Non-Coding RNA: A New Tool for the Diagnosis, Prognosis, and Therapy of Small Cell Lung Cancer

Journal of Thoracic Oncology
2015-01 | Journal article
DOI: 10.1097/jto.0000000000000394
Part of ISSN: 1556-0864
Source: Self-asserted source
Linlang Guo
grade
Preferred source (of 2)‎

Significance of PRO2000/ANCCA expression, a novel proliferation-associated protein in hepatocellular carcinoma

Cancer Cell International
2014-12 | Journal article
DOI: 10.1186/1475-2867-14-33
Part of ISSN: 1475-2867
Source: Self-asserted source
Linlang Guo

Fibroblast growth factor-inducible 14 regulates cell growth and multidrug resistance of small-cell lung cancer through the nuclear factor-κB pathway

Anti-Cancer Drugs
2014-11 | Journal article
DOI: 10.1097/cad.0000000000000153
Part of ISSN: 0959-4973
Source: Self-asserted source
Linlang Guo

Overexpression of secretagogin inhibits cell apoptosis and induces chemoresistance in small cell lung cancer under the regulation of miR-494

Oncotarget
2014-09-15 | Journal article
DOI: 10.18632/oncotarget.2305
Part of ISSN: 1949-2553
Source: Self-asserted source
Linlang Guo

Zinc finger E-box-binding homeobox 2 (ZEB2) regulated by miR-200b contributes to multi-drug resistance of small cell lung cancer

Experimental and Molecular Pathology
2014-06 | Journal article
DOI: 10.1016/j.yexmp.2014.04.008
Part of ISSN: 0014-4800
Source: Self-asserted source
Linlang Guo

Downregulation of HOXA1 gene affects small cell lung cancer cell survival and chemoresistance under the regulation of miR-100

European Journal of Cancer
2014-05 | Journal article
DOI: 10.1016/j.ejca.2014.01.024
Part of ISSN: 0959-8049
Source: Self-asserted source
Linlang Guo

MiR-296-3p regulates cell growth and multi-drug resistance of human glioblastoma by targeting ether-à-go-go (EAG1)

European Journal of Cancer
2013-02 | Journal article
DOI: 10.1016/j.ejca.2012.08.020
Part of ISSN: 0959-8049
Source: Self-asserted source
Linlang Guo

Tyrosine kinase Etk/BMX protects nasopharyngeal carcinoma cells from apoptosis induced by radiation

Cancer Biology & Therapy
2011-04 | Journal article
DOI: 10.4161/cbt.11.7.15060
Part of ISSN: 1538-4047
Part of ISSN: 1555-8576
Source: Self-asserted source
Linlang Guo

miR-126 inhibits non-small cell lung cancer cells proliferation by targeting EGFL7

Biochemical and Biophysical Research Communications
2010-01 | Journal article
DOI: 10.1016/j.bbrc.2009.12.098
Part of ISSN: 0006-291X
Source: Self-asserted source
Linlang Guo

Peer review (1 review for 1 publication/grant)

Review activity for Lung cancer. (1)
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