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Employment (1)

Northwell Health Feinstein Institutes for Medical Research: Manhasset, NY, US

2018 to present | Professor (Institute of Bioelectronic Medicine)
Employment
Source: Self-asserted source
Valentin Pavlov

Education and qualifications (2)

Robert Gordon University: Aberdeen, Aberdeen, GB

1999-04 to 2000-05 | Post Doctoral Fellow
Education
Source: Self-asserted source
Valentin Pavlov

University of Sofia "St Kliment Ohridski": Sofia, BG

1990 to 1994 | PhD in Physiology, Pathophysiology and Pharmacology (Department of Human and Animal Physiology)
Education
Source: Self-asserted source
Valentin Pavlov

Funding (3)

Brainstem Cholinergic Circuitries in the Inflammatory Reflex during Sepsis

2018-04-01 to 2023-03-31 | Grant
National Institute of General Medical Sciences (Bethesda, US)
URL: https://app.dimensions.ai/details/grant/grant.7520039
GRANT_NUMBER: R01GM128008
Source: Self-asserted source
Valentin Pavlov via DimensionsWizard

Orexinergic Modulation of Experimental Sepsis

2017-08-01 to 2021-04-30 | Grant
National Institute of General Medical Sciences (n/a, US)
URL: https://grants.uberresearch.com/100000057/R01GM121102/Orexinergic-Modulation-of-Experimental-Sepsis
GRANT_NUMBER: grant.R01GM121102
Source: Self-asserted source
Valentin Pavlov via DimensionsWizard

Central cholinergic regulation of inflammation

2011-09-30 to 2016-05-31 | Grant
National Institute of General Medical Sciences (n/a, US)
URL: https://grants.uberresearch.com/100000057/R01GM089807/Central-cholinergic-regulation-of-inflammation
GRANT_NUMBER: grant.R01GM089807
Source: Self-asserted source
Valentin Pavlov via DimensionsWizard

Works (50 of 99)

Items per page:
Page 1 of 2

Transient Receptor Potential Ankyrin-1-expressing vagus nerve fibers mediate IL-1β induced hypothermia and reflex anti-inflammatory responses

Molecular Medicine
2023-01-18 | Journal article
DOI: 10.1186/s10020-022-00590-6
Part of ISSN: 1528-3658
Contributors: Harold A. Silverman; Aisling Tynan; Tyler D. Hepler; Eric H. Chang; Manojkumar Gunasekaran; Jian Hua Li; Tomás S. Huerta; Tea Tsaava; Qing Chang; Meghan E. Addorisio et al.
Source: Self-asserted source
Valentin Pavlov
grade
Preferred source (of 2)‎

Galantamine attenuates autoinflammation in a mouse model of familial mediterranean fever.

Molecular medicine (Cambridge, Mass.)
2022-12-09 | Journal article
DOI: 10.1186/s10020-022-00571-9
PMID: 36494621
PMC: PMC9733251
Contributors: Ibrahim Mughrabi; Ochani M; Tanovic M; Wang P; Diamond B; Sherry B; Pavlov VA; Ozen S; Kastner DL; Chae JJ et al.
Source: Self-asserted source
Valentin Pavlov

A dual tracer [<sup>11</sup>C]PBR28 and [<sup>18</sup>F]FDG microPET evaluation of neuroinflammation and brain energy metabolism in murine endotoxemia.

Bioelectronic medicine
2022-11-30 | Journal article | Author
DOI: 10.1186/s42234-022-00101-2
PMID: 36451231
PMC: PMC9710165
Contributors: Palandira SP; Carrion J; Turecki L; Falvey A; Zeng Q; Liu H; Tsaava T; Herschberg D; Brines M; Chavan SS et al.
Source: Self-asserted source
Valentin Pavlov

Bioelectronic medicine: Preclinical insights and clinical advances.

Neuron
2022-09-28 | Journal article
DOI: 10.1016/j.neuron.2022.09.003
PMID: 36174571
Contributors: Pavlov VA; Tracey KJ
Source: Self-asserted source
Valentin Pavlov

Famotidine activates the vagus nerve inflammatory reflex to attenuate cytokine storm.

Molecular medicine (Cambridge, Mass.)
2022-05-16 | Journal article
DOI: 10.1186/s10020-022-00483-8
PMID: 35578169
PMC: PMC9109205
Contributors: huan yang; George SJ; Dane Thompson; Silverman HA; Tsaava T; Tynan A; Pavlov VA; Eric H Chang; Ulf Andersson; Brines M et al.
Source: Self-asserted source
Valentin Pavlov

Exploring the vagus nerve and the inflammatory reflex for therapeutic benefit in chronic spinal cord injury.

Current opinion in neurology
2022-04-01 | Journal article
DOI: 10.1097/wco.0000000000001036
PMID: 35102123
PMC: PMC9258775
Contributors: Bloom O; Tracey KJ; Pavlov VA
Source: Self-asserted source
Valentin Pavlov

Peripheral nerve stimulation and immunity: the expanding opportunities for providing mechanistic insight and therapeutic intervention.

International immunology
2022-01-01 | Journal article | Author
DOI: 10.1093/intimm/dxab068
PMID: 34498051
PMC: PMC8783605
Contributors: Falvey A; Metz CN; Tracey KJ; Valentin Pavlov
Source: Self-asserted source
Valentin Pavlov
grade
Preferred source (of 2)‎

A fully implantable wireless bidirectional neuromodulation system for mice.

Biosensors & bioelectronics
2021-12 | Journal article
DOI: 10.1016/j.bios.2021.113886
PMID: 34995836
Contributors: Wright JP; Mughrabi IT; Wong J; Mathew J; Jayaprakash N; Crosfield C; Chang EH; Chavan SS; Tracey KJ; Pavlov VA et al.
Source: Self-asserted source
Valentin Pavlov via Europe PubMed Central

HMGB1 released from nociceptors mediates inflammation.

Proceedings of the National Academy of Sciences of the United States of America
2021-08 | Journal article
DOI: 10.1073/pnas.2102034118
PMID: 34385304
PMC: PMC8379951
Contributors: Yang H; Zeng Q; Silverman HA; Gunasekaran M; George SJ; Devarajan A; Addorisio ME; Li J; Tsaava T; Shah V et al.
Source: Self-asserted source
Valentin Pavlov via Europe PubMed Central

Cholinergic stimulation with pyridostigmine modulates a heart-spleen axis after acute myocardial infarction in spontaneous hypertensive rats.

Scientific reports
2021-05 | Journal article
DOI: 10.1038/s41598-021-89104-8
PMID: 33953291
PMC: PMC8099899
Contributors: Bandoni RL; Bricher Choque PN; Dellê H; de Moraes TL; Porter MHM; da Silva BD; Neves GA; Irigoyen MC; De Angelis K; Pavlov VA et al.
Source: Self-asserted source
Valentin Pavlov via Europe PubMed Central

The Cholinergic Drug Pyridostigmine Alleviates Inflammation During LPS-Induced Acute Respiratory Distress Syndrome.

Frontiers in pharmacology
2021-05 | Journal article
DOI: 10.3389/fphar.2021.624895
PMID: 34017249
PMC: PMC8129580
Contributors: Bricher Choque PN; Vieira RP; Ulloa L; Grabulosa C; Irigoyen MC; De Angelis K; Ligeiro De Oliveira AP; Tracey KJ; Pavlov VA; Consolim-Colombo FM
Source: Self-asserted source
Valentin Pavlov via Europe PubMed Central

The Fourth Bioelectronic Medicine Summit "Technology Targeting Molecular Mechanisms": current progress, challenges, and charting the future.

Bioelectronic medicine
2021-05 | Journal article
DOI: 10.1186/s42234-021-00068-6
PMID: 34024277
PMC: PMC8142479
Contributors: Datta-Chaudhuri T; Zanos T; Chang EH; Olofsson PS; Bickel S; Bouton C; Grande D; Rieth L; Aranow C; Bloom O et al.
Source: Self-asserted source
Valentin Pavlov via Europe PubMed Central

The Cholinergic Drug Galantamine Alleviates Oxidative Stress Alongside Anti-inflammatory and Cardio-Metabolic Effects in Subjects With the Metabolic Syndrome in a Randomized Trial.

Frontiers in immunology
2021-03 | Journal article
DOI: 10.3389/fimmu.2021.613979
PMID: 33776997
PMC: PMC7991724
Contributors: Sangaleti CT; Katayama KY; De Angelis K; Lemos de Moraes T; Araújo AA; Lopes HF; Camacho C; Bortolotto LA; Michelini LC; Irigoyen MC et al.
Source: Self-asserted source
Valentin Pavlov via Europe PubMed Central

The evolving obesity challenge: targeting the vagus nerve and the inflammatory reflex in the response.

Pharmacology & therapeutics
2020-12 | Journal article
DOI: 10.1016/j.pharmthera.2020.107794
PMID: 33310156
Contributors: Pavlov VA
Source: Self-asserted source
Valentin Pavlov via Europe PubMed Central

Identification of a brainstem locus that inhibits tumor necrosis factor.

Proceedings of the National Academy of Sciences of the United States of America
2020-11 | Journal article
DOI: 10.1073/pnas.2008213117
PMID: 33168718
Contributors: Kressel AM; Tsaava T; Levine YA; Chang EH; Addorisio ME; Chang Q; Burbach BJ; Carnevale D; Lembo G; Zador AM et al.
Source: Self-asserted source
Valentin Pavlov via Europe PubMed Central

Treating disorders across the lifespan by modulating cholinergic signaling with galantamine.

Journal of neurochemistry
2020-11 | Journal article
DOI: 10.1111/jnc.15243
PMID: 33219523
Contributors: Metz CN; Pavlov VA
Source: Self-asserted source
Valentin Pavlov via Europe PubMed Central

The α7 nicotinic acetylcholine receptor agonist, GTS-21, attenuates hyperoxia-induced acute inflammatory lung injury by alleviating the accumulation of HMGB1 in the airways and the circulation.

Molecular medicine (Cambridge, Mass.)
2020-06 | Journal article
DOI: 10.1186/s10020-020-00177-z
PMID: 32600307
PMC: PMC7322715
Contributors: Sitapara RA; Gauthier AG; Valdés-Ferrer SI; Lin M; Patel V; Wang M; Martino AT; Perron JC; Ashby CR; Tracey KJ et al.
Source: Self-asserted source
Valentin Pavlov via Europe PubMed Central

Auricular neural stimulation as a new non-invasive treatment for opioid detoxification.

Bioelectronic medicine
2020-03 | Journal article
DOI: 10.1186/s42234-020-00044-6
PMID: 32266304
PMC: PMC7110792
Contributors: Qureshi IS; Datta-Chaudhuri T; Tracey KJ; Pavlov VA; Chen ACH
Source: Self-asserted source
Valentin Pavlov via Europe PubMed Central

Building a bioelectronic medicine movement 2019: insights from leaders in industry, academia, and research.

Bioelectronic medicine
2020-01 | Journal article
DOI: 10.1186/s42234-020-0037-8
PMID: 32232110
PMC: PMC7098241
Contributors: Alliance for Advancing Bioelectronic Medicine
Source: Self-asserted source
Valentin Pavlov via Europe PubMed Central

Galantamine alleviates oxidative stress alongside anti-inflammatory and cardio-metabolic effects in subjects with the metabolic syndrome in a randomized trial

2020-01 | Preprint
DOI: 10.1101/2019.12.30.19016105
OTHER-ID:

PPR107461
Contributors: Sangaleti CT; Katayama KY; De Angelis K; de Moraes TL; Araújo AA; Lopes HF; Camacho C; Bortolotto LA; Michelini LC; Irigoyen MC et al.
Source: Self-asserted source
Valentin Pavlov via Europe PubMed Central

Post-sepsis syndrome - an evolving entity that afflicts survivors of sepsis.

Molecular medicine (Cambridge, Mass.)
2019-12 | Journal article
DOI: 10.1186/s10020-019-0132-z
PMID: 31892321
PMC: PMC6938630
Contributors: Mostel Z; Perl A; Marck M; Mehdi SF; Lowell B; Bathija S; Santosh R; Pavlov VA; Chavan SS; Roth J
Source: Self-asserted source
Valentin Pavlov via Europe PubMed Central

Transient Receptor Potential Ankyrin 1 Mediates Afferent Signals in the Inflammatory Reflex

2019-11 | Preprint
DOI: 10.1101/822734
OTHER-ID:

PPR100970
Contributors: Silverman HA; Gunasekaran M; Chang EH; Chang Q; Addorisio ME; Stiegler A; Kressel AM; Li JH; Tsaava T; Huerta TS et al.
Source: Self-asserted source
Valentin Pavlov via Europe PubMed Central

Characterization of inflammation and insulin resistance in high-fat diet-induced male C57BL/6J mouse model of obesity.

Animal models and experimental medicine
2019-09 | Journal article
DOI: 10.1002/ame2.12084
PMID: 31942557
PMC: PMC6930989
Contributors: Avtanski D; Pavlov VA; Tracey KJ; Poretsky L
Source: Self-asserted source
Valentin Pavlov via Europe PubMed Central

An Effective Method for Acute Vagus Nerve Stimulation in Experimental Inflammation.

Frontiers in neuroscience
2019-08 | Journal article
DOI: 10.3389/fnins.2019.00877
PMID: 31551672
PMC: PMC6736627
Contributors: Caravaca AS; Gallina AL; Tarnawski L; Tracey KJ; Pavlov VA; Levine YA; Olofsson PS
Source: Self-asserted source
Valentin Pavlov via Europe PubMed Central

Bioelectronic Medicine: From Preclinical Studies on the Inflammatory Reflex to New Approaches in Disease Diagnosis and Treatment

Cold Spring Harbor Perspectives in Medicine
2019-05-28 | Journal article
DOI: 10.1101/cshperspect.a034140
Part of ISSN: 2157-1422
Source: Self-asserted source
Valentin Pavlov

Collateral benefits of studying the vagus nerve in bioelectronic medicine

Bioelectronic Medicine
2019-05-16 | Journal article
DOI: 10.1186/s42234-019-0021-3
Part of ISSN: 2332-8886
Source: Self-asserted source
Valentin Pavlov

Buprenorphine Markedly Elevates a Panel of Surrogate Markers in a Murine Model of Sepsis

SHOCK
2019-04 | Journal article
DOI: 10.1097/shk.0000000000001361
Part of ISSN: 1073-2322
Source: Self-asserted source
Valentin Pavlov

Investigational treatment of rheumatoid arthritis with a vibrotactile device applied to the external ear

Bioelectronic Medicine
2019-04-17 | Journal article
DOI: 10.1186/s42234-019-0020-4
Part of ISSN: 2332-8886
Source: Self-asserted source
Valentin Pavlov

Cholinergic Control of Inflammation, Metabolic Dysfunction, and Cognitive Impairment in Obesity-Associated Disorders: Mechanisms and Novel Therapeutic Opportunities.

Frontiers in neuroscience
2019-04-05 | Journal article
DOI: 10.3389/fnins.2019.00263
PMID: 31024226
PMC: PMC6460483
Source: Self-asserted source
Valentin Pavlov

Forebrain Cholinergic Signaling Regulates Innate Immune Responses and Inflammation.

Frontiers in immunology
2019-04-02 | Journal article
DOI: 10.3389/fimmu.2019.00585
PMID: 31024522
PMC: PMC6455130
Source: Self-asserted source
Valentin Pavlov

Bioelectronic medicine: updates, challenges and paths forward

Bioelectronic Medicine
2019-01-22 | Journal article
DOI: 10.1186/s42234-019-0018-y
Part of ISSN: 2332-8886
Source: Self-asserted source
Valentin Pavlov

Editorial: Neuro-Immune Interactions in Inflammation and Autoimmunity.

Frontiers in immunology
2018 | Journal article
DOI: 10.3389/fimmu.2018.00772
PMID: 29713326
PMC: PMC5911455
Contributors: Terrando N; Pavlov VA
Source: Self-asserted source
Valentin Pavlov via Europe PubMed Central

Adenylyl Cyclase 6 Mediates Inhibition of TNF in the Inflammatory Reflex.

Frontiers in immunology
2018-11-27 | Journal article
DOI: 10.3389/fimmu.2018.02648
PMID: 30538698
PMC: PMC6277584
Source: Self-asserted source
Valentin Pavlov

Reuniting Overnutrition and Undernutrition, Macronutrients and Micronutrients.

Diabetes/metabolism research and reviews
2018-09 | Journal article
DOI: 10.1002/dmrr.3072
PMID: 30171821
Contributors: Kim M; Basharat A; Santosh R; Mehdi SF; Razvi Z; Yoo SK; Lowell B; Kumar A; Brima W; Danoff A et al.
Source: Self-asserted source
Valentin Pavlov via Europe PubMed Central

Vagus nerve cholinergic circuitry to the liver and the gastrointestinal tract in the neuroimmune communicatome.

American journal of physiology. Gastrointestinal and liver physiology
2018-07 | Journal article
DOI: 10.1152/ajpgi.00195.2018
PMID: 30001146
Contributors: Metz CN; Pavlov VA
Source: Self-asserted source
Valentin Pavlov via Europe PubMed Central

Molecular and Functional Neuroscience in Immunity.

Annual review of immunology
2018-04 | Journal article
DOI: 10.1146/annurev-immunol-042617-053158
PMID: 29677475
Contributors: Pavlov VA; Chavan SS; Tracey KJ
Source: Self-asserted source
Valentin Pavlov via Europe PubMed Central

Activation of the cholinergic anti-inflammatory pathway by GTS-21 attenuates cisplatin-induced acute kidney injury in mice.

PloS one
2017 | Journal article
DOI: 10.1371/journal.pone.0188797
PMID: 29190774
PMC: PMC5708817
Contributors: Chatterjee PK; Yeboah MM; Solanki MH; Kumar G; Xue X; Pavlov VA; Al-Abed Y; Metz CN
Source: Self-asserted source
Valentin Pavlov via Europe PubMed Central

Forebrain Cholinergic Dysfunction and Systemic and Brain Inflammation in Murine Sepsis Survivors.

Frontiers in immunology
2017 | Journal article
DOI: 10.3389/fimmu.2017.01673
PMID: 29326685
PMC: PMC5736570
Contributors: Zaghloul N; Addorisio ME; Silverman HA; Patel HL; Valdés-Ferrer SI; Ayasolla KR; Lehner KR; Olofsson PS; Nasim M; Metz CN et al.
Source: Self-asserted source
Valentin Pavlov via Europe PubMed Central

Nicotinic Acetylcholine Receptor—Mediated Protection of the Rat Heart Exposed to Ischemia Reperfusion

Molecular Medicine
2017 | Journal article
DOI: 10.2119/molmed.2017.00091
Contributors: Spyros A Mavropoulos; Nayaab S Khan
Source: Self-asserted source
Valentin Pavlov via Crossref Metadata Search

Rodent Models of Diabetes

Principles of Diabetes Mellitus
2017 | Other
DOI: 10.1007/978-3-319-18741-9_11
Contributors: Christine N. Metz; LaQueta K. Hudson; Valentin A. Pavlov
Source: Self-asserted source
Valentin Pavlov via Crossref Metadata Search

The Neuroimmune Communicatome in Inflammation

Inflammation - From Molecular and Cellular Mechanisms to the Clinic
2017-10 | Other
DOI: 10.1002/9783527692156.ch59
Contributors: Peder S. Olofsson; Christine N. Metz; Valentin A. Pavlov
Source: Self-asserted source
Valentin Pavlov via Crossref Metadata Search

Galantamine alleviates inflammation and insulin resistance in patients with metabolic syndrome in a randomized trial

JCI Insight
2017-07 | Journal article
DOI: 10.1172/jci.insight.93340
Contributors: Fernanda M. Consolim-Colombo; Carine T. Sangaleti; Fernando O. Costa; Tercio L. Morais; Heno F. Lopes; Josiane M. Motta; Maria C. Irigoyen; Luiz A. Bortoloto; Carlos Eduardo Rochitte; Yael Tobi Harris et al.
Source: Self-asserted source
Valentin Pavlov via Crossref Metadata Search

Mechanisms and Therapeutic Relevance of Neuro-immune Communication

Immunity
2017-06 | Journal article
DOI: 10.1016/j.immuni.2017.06.008
Contributors: Sangeeta S. Chavan; Valentin A. Pavlov; Kevin J. Tracey
Source: Self-asserted source
Valentin Pavlov via Crossref Metadata Search

Neural regulation of immunity: molecular mechanisms and clinical translation

Nature Neuroscience
2017-01 | Journal article
DOI: 10.1038/nn.4477
Contributors: Valentin A Pavlov; Kevin J Tracey
Source: Self-asserted source
Valentin Pavlov via Crossref Metadata Search

Emetine Di-HCl Attenuates Type 1 Diabetes Mellitus in Mice

Molecular Medicine
2016 | Journal article
DOI: 10.2119/molmed.2016.00082
Contributors: LaQueta K Hudson; Meghan E Dancho
Source: Self-asserted source
Valentin Pavlov via Crossref Metadata Search

Obesity Paradox, Obesity Orthodox, and the Metabolic Syndrome: An Approach to Unity

Molecular Medicine
2016 | Journal article
DOI: 10.2119/molmed.2016.00211
Contributors: Jesse Roth; Navneet Sahota
Source: Self-asserted source
Valentin Pavlov via Crossref Metadata Search

Blood pressure regulation by CD4+ lymphocytes expressing choline acetyltransferase

Nature Biotechnology
2016-09 | Journal article
DOI: 10.1038/nbt.3663
Contributors: Peder S Olofsson; Benjamin E Steinberg; Roozbeh Sobbi; Maureen A Cox; Mohamed N Ahmed; Michaela Oswald; Ferenc Szekeres; William M Hanes; Andrea Introini; Shu Fang Liu et al.
Source: Self-asserted source
Valentin Pavlov via Crossref Metadata Search

Single-pulse and unidirectional activation of the cervical vagus nerve reduces tumor necrosis factor in endotoxemia

Bioelectronic Medicine
2015 | Journal article
Source: Self-asserted source
Valentin Pavlov

Neural circuitry and immunity

Immunologic Research
2015-10 | Journal article
DOI: 10.1007/s12026-015-8718-1
Contributors: Valentin A. Pavlov; Kevin J. Tracey
Source: Self-asserted source
Valentin Pavlov via Crossref Metadata Search

Galantamine Attenuates Type 1 Diabetes and Inhibits Anti-Insulin Antibodies in Non-Obese Diabetic Mice.

Molecular Medicine
2015-08 | Journal article
DOI: 10.2119/molmed.2015.00142
PMID: 26322849
PMC: PMC4749496
Source: Self-asserted source
Valentin Pavlov via Europe PubMed Central
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