Personal information

Websites & social links

ResearchGate
University of Barcelona
Massachusetts Institute of Technology
FCRB/IDIBAPS - Hospital Clinic de Barcelona
Linkedin
Twitter

Other IDs

Scopus Author ID: 8563913900
ResearcherID: S-3446-2016
SciProfiles: 1143050

Keywords

wound healing, liver regeneration, nanoparticles, cell therapy, immune system

Countries

Spain

Activities

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Employment (5)

Massachusetts Institute of Technology: Cambridge, MA, US

Employment
Source: check_circle
Massachusetts Institute of Technology

Universitat de Barcelona: Barcelona, ES

2024-11-27 to present | Tenured Professor (Associate Professor) (Department of Biomedicine)
Employment
Source: Self-asserted source
0000-0002-2009-5911

Consorci Institut D'Investigacions Biomediques August Pi I Sunyer: Barcelona, ES

2017 to present | Research Affiliate
Employment
Source: Self-asserted source
0000-0002-2009-5911

University of Barcelona: Barcelona, ES

2020-03-01 to 2024-11-26 | Ramon y Cajal Researcher (Biomedicine)
Employment
Source: Self-asserted source
0000-0002-2009-5911

Institute of Advanced Chemistry of Catalonia, (IQAC) & Faculty of Pharmacy, University of Barcelona: Barcelona, ES

2011 to 2013 | Postdoctoral Fellow (Department of Chemical and Biomolecular Nanotechnology, CSIC. & Department of Pharmacy and Pharmaceutical Technology, UB.)
Employment
Source: Self-asserted source
0000-0002-2009-5911

Education and qualifications (3)

University of Barcelona: Barcelona, ES

2004 to 2010 | PhD in Biomedicine (Biochemistry and Molecul;ar Genetics Department, Hospital Clinic de Barcelona)
Education
Source: Self-asserted source
0000-0002-2009-5911

University of Barcelona: Barcelona, ES

2001 to 2003 | Bachelor Degree in Biochemistry
Education
Source: Self-asserted source
0000-0002-2009-5911

University of Barcelona: Barcelona, ES

1996 to 2001 | Bachelor Degree in Pharmacy
Education
Source: Self-asserted source
0000-0002-2009-5911

Professional activities (3)

Asociación Española para el Estudio del Hígado: Madrid, ES

2017 to present
Membership
Source: Self-asserted source
0000-0002-2009-5911

Spanish Society for Biochemistry and Molecular Biology: Madrid, ES

2015 to present | Member
Membership
Source: Self-asserted source
0000-0002-2009-5911

College of Pharmacists of Barcelona: Barcelona, ES

2010 to present | Member
Membership
Source: Self-asserted source
0000-0002-2009-5911

Funding (12)

Caracterización del cambio de perfil de expresión génica y fenotipo que ex-perimentan los macrófagos en presencia de células de cáncer de hígado

2024-01 to 2026-01 | Grant
Fundación Eugenio Rodríguez Pascual (Madrid, ES)
Source: Self-asserted source
0000-0002-2009-5911

Matrix screening for accurate reproduction of the architecture and the physiological and pathophysiological cellular response of the liver (MASCARA)

2023 to 2025 | Grant
Ministerio de Ciencia e Innovación (Madrid, ES)
GRANT_NUMBER:

CNS2022-135148
Source: Self-asserted source
0000-0002-2009-5911

NUEVAS NANOTERAPIAS PARA TRATAR LA HIPERTENSION PORTAL Y LA FIBROSIS HEPATICA EN HUMANOS: VALIDACION Y ESCALADO DEL PROCESO DE PRODUCCION

2023 to 2025 | Grant
Ministerio de Ciencia e Innovación (Madrid, ES)
GRANT_NUMBER:

PDC2022-133780-C21
Source: Self-asserted source
0000-0002-2009-5911

Novel immunomodulatory engineered therapeutic strategies for liver diseases: matrix-embedded endothelial cells and macrophage-targeted dendrimer nanoparticles (ENGILIVE)

2022 to 2025 | Grant
Ministerio de Ciencia e Innovación (Madrid, ES)
GRANT_NUMBER:

PID2021-123426OB-I00
Source: Self-asserted source
0000-0002-2009-5911

RedFibro

2022 to 2024 | Grant
Ministerio de Ciencia e Innovación (Madrid, ES)
GRANT_NUMBER:

RED2022-134485-T
Source: Self-asserted source
0000-0002-2009-5911

Grupo de Investigación Traslacional en Nuevas Estrategias de Diagnóstico y Tratamiento de la Enfermedad Hepática

2021 to 2024 | Grant
Generalitat de Catalunya (Barcelona, ES)
GRANT_NUMBER:

2021 SGR 00881
Source: Self-asserted source
0000-0002-2009-5911

Translational research in biomedicine to design new strategies for the therapy and diagnostic of liver diseases

2020 to 2025 | Grant
Ministerio de Ciencia e Innovación (Madrid, ES)
GRANT_NUMBER:

RYC2018-023971-I
Source: Self-asserted source
0000-0002-2009-5911

FEASIBILITY AND THERAPEUTIC UTILITY OF NOVEL TREATMENTS IN LIVER DISEASES: PTTG1mRNA INTERFERENCE, CARBON GRAPHITE NANOPARTICLES AND TARGETED NITRIC OXIDE DONORS (INANOLIVE)

2018 to 2021 | Award
Ministry of Science and Innovation (Madrid, ES)
Source: Self-asserted source
0000-0002-2009-5911

Modulation of monocyte-endothelial cells interaction using cell therapy in liver regeneration

2014 to 2016 | Salary award
Agency for Management of University and Research Grants (Barcelona, ES)
GRANT_NUMBER:

2013 BP_A 00051
Source: Self-asserted source
0000-0002-2009-5911

Effects of the interaction of monocyte-endothelial cells in the regulation of liver angiogeneis and regeneration

2013 to 2014 | Salary award
Fundación Alfonso Martín Escudero (Madrid, ES)
Source: Self-asserted source
0000-0002-2009-5911

Study of new technologies in liver disease

2011 to 2013 | Salary award
Spanish Association for the Study of Liver (Madrid, ES)
Source: Self-asserted source
0000-0002-2009-5911

Program Formación de Personal Investigador (FPI)

2004 to 2010 | Salary award
Spanish Ministry of Culture and Education (Madrid, ES)
GRANT_NUMBER:

EX 9938446345
Source: Self-asserted source
0000-0002-2009-5911

Works (44)

Identification of Dhx15 as a Major Regulator of Liver Development, Regeneration, and Tumor Growth in Zebrafish and Mice

International Journal of Molecular Sciences
2024 | Journal article
DOI: 10.3390/ijms25073716
EID:

2-s2.0-85190361797

Part of ISSN: 14220067 16616596
Contributors: Portolés, I.; Ribera, J.; Fernandez-Galán, E.; Lecue, E.; Casals, G.; Melgar-Lesmes, P.; Fernández-Varo, G.; Boix, L.; Sanduzzi, M.; Aishwarya, V. et al.
Source: Self-asserted source
0000-0002-2009-5911 via Scopus - Elsevier
grade
Preferred source (of 3)‎

Liver-targeted nanoparticles delivering nitric oxide reduce portal hypertension in cirrhotic rats

Biomedicine and Pharmacotherapy
2024 | Journal article
DOI: 10.1016/j.biopha.2024.116143
EID:

2-s2.0-85182363817

Part of ISSN: 19506007 07533322
Contributors: Perramón, M.; Navalón-López, M.; Fernández-Varo, G.; Moreno-Lanceta, A.; García-Pérez, R.; Faneca, J.; López-Moya, M.; Fornaguera, C.; García-Villoria, J.; Morales-Ruiz, M. et al.
Source: Self-asserted source
0000-0002-2009-5911 via Scopus - Elsevier

Nano-navigated macrophages: Piercing liver inflammation, fibrosis, and cancer

Matter
2024 | Journal article
DOI: 10.1016/j.matt.2024.09.003
EID:

2-s2.0-85207712769

Part of ISSN: 25902385 25902393
Contributors: Moreno-Lanceta, A.; Edelman, E.R.; Conde, J.; Melgar-Lesmes, P.
Source: Self-asserted source
0000-0002-2009-5911 via Scopus - Elsevier

Reprogramming macrophages to treat liver diseases

Hepatology
2024-11-12 | Journal article
DOI: 10.1097/HEP.0000000000001160
Contributors: Blanca Simón-Codina; Júlia Cacho-Pujol; Anna Moles; Pedro Melgar-Lesmes
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Atherosclerotic plaque development in mice is enhanced by myeloid ZEB1 downregulation

Nature Communications
2023 | Journal article
DOI: 10.1038/s41467-023-43896-7
EID:

2-s2.0-85179717651

Part of ISSN: 20411723
Contributors: Martinez-Campanario, M.C.; Cortés, M.; Moreno-Lanceta, A.; Han, L.; Ninfali, C.; Domínguez, V.; Andrés-Manzano, M.J.; Farràs, M.; Esteve-Codina, A.; Enrich, C. et al.
Source: Self-asserted source
0000-0002-2009-5911 via Scopus - Elsevier

Monocyte-endothelial cell interactions in vascular and tissue remodeling

Frontiers in Immunology
2023 | Journal article
DOI: 10.3389/fimmu.2023.1196033
EID:

2-s2.0-85165272870

Part of ISSN: 16643224
Contributors: Medrano-Bosch, M.; Simón-Codina, B.; Jiménez, W.; Edelman, E.R.; Melgar-Lesmes, P.
Source: Self-asserted source
0000-0002-2009-5911 via Scopus - Elsevier

Optimization of 3D autologous chondrocyte-seeded polyglycolic acid scaffolds to mimic human ear cartilage

Biomaterials Science
2023 | Journal article
DOI: 10.1039/D3BM00035D
Contributors: Pedro Melgar-Lesmes; Oriol Bosch; Rebecca Zubajlo; Gemma Molins; Sofia Comfort; Ainara Luque-Saavedra; Mario López-Moya; Fernando García-Polite; Francisco José Parri Ferrandis; Carolyn Rogers et al.
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Tcf20 deficiency is associated with increased liver fibrogenesis and alterations in mitochondrial metabolism in mice and humans

Liver International
2023 | Journal article
DOI: 10.1111/liv.15640
EID:

2-s2.0-85163139135

Part of ISSN: 14783231 14783223
Contributors: Córdoba-Jover, B.; Ribera, J.; Portolés, I.; Lecue, E.; Rodriguez-Vita, J.; Pérez-Sisqués, L.; Mannara, F.; Solsona-Vilarrasa, E.; García-Ruiz, C.; Fernández-Checa, J.C. et al.
Source: Self-asserted source
0000-0002-2009-5911 via Scopus - Elsevier

RNF41 orchestrates macrophage-driven fibrosis resolution and hepatic regeneration

Science Translational Medicine
2023-07-12 | Journal article | Author
DOI: 10.1126/scitranslmed.abq6225
Part of ISSN: 1946-6234
Part of ISSN: 1946-6242
Contributors: Alazne Moreno Lanceta; Mireia Medrano Bosch; Yiliam Fundora Suarez; Meritxell Perramón; Jessica Aspas; Marina Parra-Robert; Sheila Baena Benito; Constantino Fondevila; Elazer R Edelman; Wladimiro Jiménez et al.
Source: Self-asserted source
0000-0002-2009-5911
grade
Preferred source (of 2)‎

PPAR-γ Agonist GW1929 Targeted to Macrophages with Dendrimer–Graphene Nanostars Reduces Liver Fibrosis and Inflammation

Pharmaceutics
2023-05-10 | Journal article
DOI: 10.3390/pharmaceutics15051452
Contributors: Alazne Moreno-Lanceta; Mireia Medrano-Bosch; Blanca Simón-Codina; Montserrat Barber-González; Wladimiro Jiménez; Pedro Melgar-Lesmes
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Polymeric Nanoparticles for Targeted Drug and Gene Delivery Systems

Nanotechnology in the Life Sciences
2022 | Book chapter
DOI: 10.1007/978-3-031-12658-1_19
EID:

2-s2.0-85140762596

Part of ISSN: 25238035 25238027
Contributors: Moreno-Lanceta, A.; Medrano-Bosch, M.; Edelman, E.R.; Melgar-Lesmes, P.
Source: Self-asserted source
0000-0002-2009-5911 via Scopus - Elsevier

The pituitary tumour‐transforming gene 1/delta‐like homologue 1 pathway plays a key role in liver fibrogenesis

Liver International
2022-03 | Journal article
DOI: 10.1111/liv.15165
Contributors: Meritxell Perramón; Silvia Carvajal; Vedrana Reichenbach; Guillermo Fernández‐Varo; Loreto Boix; Laura Macias‐Muñoz; Pedro Melgar‐Lesmes; Jordi Bruix; Shlomo Melmed; Santiago Lamas et al.
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Ethylcellulose nanoparticles prepared from nano-emulsion templates as new folate binding haemocompatible platforms

Materials Science and Engineering C
2021 | Journal article
DOI: 10.1016/j.msec.2020.111682
EID:

2-s2.0-85094874536

Part of ISSN: 18730191 09284931
Contributors: Leitner, S.; Solans, C.; García-Celma, M.J.; Morral-Ruíz, G.; Melgar-Lesmes, P.; Calderó, G.
Source: Self-asserted source
0000-0002-2009-5911 via Scopus - Elsevier

Nanoparticles to Target and Treat Macrophages: The Ockham’s Concept?

Pharmaceutics
2021-08-26 | Journal article
DOI: 10.3390/pharmaceutics13091340
Contributors: Mireia Medrano-Bosch; Alazne Moreno-Lanceta; Pedro Melgar-Lesmes
Source: check_circle
Crossref
grade
Preferred source (of 3)‎

Single-Walled Carbon Nanohorns as Promising Nanotube-Derived Delivery Systems to Treat Cancer

Pharmaceutics
2020-09-07 | Journal article
DOI: 10.3390/pharmaceutics12090850
Contributors: Alazne Moreno-Lanceta; Mireia Medrano-Bosch; Pedro Melgar-Lesmes
Source: check_circle
Crossref
grade
Preferred source (of 3)‎

Cerium Oxide Nanoparticles Protect against Oxidant Injury and Interfere with Oxidative Mediated Kinase Signaling in Human-Derived Hepatocytes

International Journal of Molecular Sciences
2019-11-27 | Journal article
DOI: 10.3390/ijms20235959
Contributors: Silvia Carvajal; Meritxell Perramón; Gregori Casals; Denise Oró; Jordi Ribera; Manuel Morales-Ruiz; Eudald Casals; Pedro Casado; Pedro Melgar-Lesmes; Guillermo Fernández-Varo et al.
Source: check_circle
Crossref
grade
Preferred source (of 3)‎

Roles of the Hepatic Endocannabinoid and Apelin Systems in the Pathogenesis of Liver Fibrosis

Cells
2019-10-24 | Journal article
DOI: 10.3390/cells8111311
Contributors: Pedro Melgar-Lesmes; Meritxell Perramon; Wladimiro Jiménez
Source: check_circle
Crossref
grade
Preferred source (of 3)‎

Chondroitin Sulphate Attenuates Atherosclerosis in ApoE Knockout Mice Involving Cellular Regulation of the Inflammatory Response

Thrombosis and Haemostasis
2018 | Journal article
DOI: 10.1055/s-0038-1657753
EID:

2-s2.0-85048165244

Part of ISSN: 03406245
Contributors: Melgar-Lesmes, P.; Sánchez-Herrero, A.; Lozano-Juan, F.; De La Torre Hernández, J.M.; Montell, E.; Jiménez, W.; Edelman, E.R.; Balcells, M.
Source: Self-asserted source
0000-0002-2009-5911 via Scopus - Elsevier

Graphene–Dendrimer Nanostars for Targeted Macrophage Overexpression of Metalloproteinase 9 and Hepatic Fibrosis Precision Therapy

Nano Letters
2018-09-12 | Journal article
DOI: 10.1021/acs.nanolett.8b02498
Contributors: Pedro Melgar-Lesmes; Aureli Luquero; Marina Parra-Robert; Adriana Mora; Jordi Ribera; Elazer R. Edelman; Wladimiro Jiménez
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Optimizing Glutaraldehyde-Fixed Tissue Heart Valves with Chondroitin Sulfate Hydrogel for Endothelialization and Shielding against Deterioration

Biomacromolecules
2018-04-09 | Journal article
DOI: 10.1021/acs.biomac.8b00077
Contributors: Mario Lopez-Moya; Pedro Melgar-Lesmes; Kumaran Kolandaivelu; Jose María de la Torre Hernández; Elazer R. Edelman; Mercedes Balcells
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

A small population of liver endothelial cells undergoes endothelial-tomesenchymal transition in response to chronic liver injury

American Journal of Physiology - Gastrointestinal and Liver Physiology
2017 | Journal article
DOI: 10.1152/ajpgi.00428.2016
EID:

2-s2.0-85033237920

Part of ISSN: 15221547 01931857
Contributors: Ribera, J.; Pauta, M.; Melgar-Lesmes, P.; Córdoba, B.; Bosch, A.; Calvo, M.; Rodrigo-Torres, D.; Sancho-Bru, P.; Mira, A.; Jiménez, W. et al.
Source: Self-asserted source
0000-0002-2009-5911 via Scopus - Elsevier

Implantation of healthy matrix-embedded endothelial cells rescues dysfunctional endothelium and ischaemic tissue in liver engraftment

Gut
2017 | Journal article
DOI: 10.1136/gutjnl-2015-310409
EID:

2-s2.0-84958068916
Contributors: Melgar-Lesmes, P.; Balcells, M.; Edelman, E.R.
Source: Self-asserted source
0000-0002-2009-5911 via Scopus - Elsevier

Pulsatility and high shear stress deteriorate barrier phenotype in brain microvascular endothelium

Journal of Cerebral Blood Flow and Metabolism
2017 | Journal article
DOI: 10.1177/0271678X16672482
EID:

2-s2.0-85021066590

Part of ISSN: 15597016 0271678X
Contributors: Garcia-Polite, F.; Martorell, J.; Del Rey-Puech, P.; Melgar-Lesmes, P.; O’Brien, C.C.; Roquer, J.; Ois, A.; Principe, A.; Edelman, E.R.; Balcells, M.
Source: Self-asserted source
0000-0002-2009-5911 via Scopus - Elsevier

Polyurethane Nanoparticles, a New Tool for Biomedical Applications?

Advances in Polyurethane Biomaterials
2016 | Book chapter
Part of DOI: 10.1016/B978-0-08-100614-6.00007-X
EID:

2-s2.0-84967268101
Contributors: Morral-Ruíz, G.; Melgar-Lesmes, P.; Solans, C.; García-Celma, M.J.
Source: Self-asserted source
0000-0002-2009-5911 via Scopus - Elsevier

Treatment with chondroitin sulfate to modulate inflammation and atherogenesis in obesity

Atherosclerosis
2016 | Journal article
DOI: 10.1016/j.atherosclerosis.2015.12.016
EID:

2-s2.0-84949844180
Contributors: Melgar-Lesmes, P.; Garcia-Polite, F.; Del-Rey-Puech, P.; Rosas, E.; Dreyfuss, J.L.; Montell, E.; Vergés, J.; Edelman, E.R.; Balcells, M.
Source: Self-asserted source
0000-0002-2009-5911 via Scopus - Elsevier

Biotinylated polyurethane-urea nanoparticles for targeted theranostics in human hepatocellular carcinoma

Nano Research
2015 | Journal article
DOI: 10.1007/s12274-014-0678-6
EID:

2-s2.0-84940008444
Contributors: Morral-Ruíz, G.; Melgar-Lesmes, P.; López-Vicente, A.; Solans, C.; García-Celma, M.J.
Source: Self-asserted source
0000-0002-2009-5911 via Scopus - Elsevier

Monocyte-endothelial cell interactions in the regulation of vascular sprouting and liver regeneration in mouse

Journal of Hepatology
2015 | Journal article
DOI: 10.1016/j.jhep.2015.05.011
EID:

2-s2.0-84941941384
Contributors: Melgar-Lesmes, P.; Edelman, E.R.
Source: Self-asserted source
0000-0002-2009-5911 via Scopus - Elsevier

Overexpression of angiopoietin-2 in rats and patients with liver fibrosis. Therapeutic consequences of its inhibition

Liver International
2015 | Journal article
DOI: 10.1111/liv.12505
EID:

2-s2.0-84924591909
Contributors: Pauta, M.; Ribera, J.; Melgar-Lesmes, P.; Casals, G.; Rodríguez-Vita, J.; Reichenbach, V.; Fernandez-Varo, G.; Morales-Romero, B.; Bataller, R.; Michelena, J. et al.
Source: Self-asserted source
0000-0002-2009-5911 via Scopus - Elsevier

Extent of flow recirculation governs expression of atherosclerotic and thrombotic biomarkers in arterial bifurcations

Cardiovascular Research
2014 | Journal article
DOI: 10.1093/cvr/cvu124
EID:

2-s2.0-84903994927
Contributors: Martorell, J.; Santomá, P.; Kolandaivelu, K.; Kolachalama, V.B.; Melgar-Lesmes, P.; Molins, J.J.; Garcia, L.; Edelman, E.R.; Balcells, M.
Source: Self-asserted source
0000-0002-2009-5911 via Scopus - Elsevier

Polyurethane and polyurea nanoparticles based on polyoxyethylene castor oil derivative surfactant suitable for endovascular applications

International Journal of Pharmaceutics
2014 | Journal article
DOI: 10.1016/j.ijpharm.2013.11.026
EID:

2-s2.0-84888989218
Contributors: Morral-Ruíz, G.; Melgar-Lesmes, P.; García, M.L.; Solans, C.; García-Celma, M.J.
Source: Self-asserted source
0000-0002-2009-5911 via Scopus - Elsevier

Quantifying the bioadhesive properties of surface-modified polyurethane-urea nanoparticles in the vascular network

Colloids and Surfaces B: Biointerfaces
2014 | Journal article
DOI: 10.1016/j.colsurfb.2014.03.041
EID:

2-s2.0-84900794528
Contributors: Melgar-Lesmes, P.; Morral-Ruíz, G.; Solans, C.; García-Celma, M.J.
Source: Self-asserted source
0000-0002-2009-5911 via Scopus - Elsevier

Factors involved in extracellular matrix turnover in human derived cardiomyocytes

Cellular Physiology and Biochemistry
2013 | Journal article
DOI: 10.1159/000354513
EID:

2-s2.0-84890728617
Contributors: Casals, G.; Fernández-Varo, G.; Melgar-Lesmes, P.; Marfà, S.; Reichenbach, V.; Morales-Ruiz, M.; Jiménez, W.
Source: Self-asserted source
0000-0002-2009-5911 via Scopus - Elsevier

Increased nitric oxide production in lymphatic endothelial cells causes impairment of lymphatic drainage in cirrhotic rats

Gut
2013 | Journal article
DOI: 10.1136/gutjnl-2011-300703
EID:

2-s2.0-84871129149
Contributors: Ribera, J.; Pauta, M.; Melgar-Lesmes, P.; Tugues, S.; Fernández-Varo, G.; Held, K.F.; Soria, G.; Tudela, R.; Planas, A.M.; Fernández-Hernando, C. et al.
Source: Self-asserted source
0000-0002-2009-5911 via Scopus - Elsevier

Multifunctional polyurethane-urea nanoparticles to target and arrest inflamed vascular environment: A potential tool for cancer therapy and diagnosis

Journal of Controlled Release
2013 | Journal article
DOI: 10.1016/j.jconrel.2013.06.027
EID:

2-s2.0-84881166445
Contributors: Morral-Ruíz, G.; Melgar-Lesmes, P.; Solans, C.; García-Celma, M.J.
Source: Self-asserted source
0000-0002-2009-5911 via Scopus - Elsevier

Adenoviral dominant-negative soluble PDGFRβ improves hepatic collagen, systemic hemodynamics, and portal pressure in fibrotic rats

Journal of Hepatology
2012 | Journal article
DOI: 10.1016/j.jhep.2012.07.012
EID:

2-s2.0-84867574469
Contributors: Reichenbach, V.; Fernández-Varo, G.; Casals, G.; Oró, D.; Ros, J.; Melgar-Lesmes, P.; Weiskirchen, R.; Morales-Ruiz, M.; Jiménez, W.
Source: Self-asserted source
0000-0002-2009-5911 via Scopus - Elsevier

Design of biocompatible surface-modified polyurethane and polyurea nanoparticles

Polymer (United Kingdom)
2012 | Journal article
DOI: 10.1016/j.polymer.2012.10.039
EID:

2-s2.0-84870255395
Contributors: Morral-Ruíz, G.; Melgar-Lesmes, P.; García, M.L.; Solans, C.; García-Celma, M.J.
Source: Self-asserted source
0000-0002-2009-5911 via Scopus - Elsevier

Prevention of fibrosis progression in CCl <sub>4</sub>-Treated rats: Role of the hepatic endocannabinoid and apelin systems

Journal of Pharmacology and Experimental Therapeutics
2012 | Journal article
DOI: 10.1124/jpet.111.188078
EID:

2-s2.0-84857311013

Part of ISSN: 00223565 15210103
Contributors: Reichenbach, V.; Ros, J.; Fernández-Varo, G.; Casals, G.; Melgar-Lesmes, P.; Campos, T.; Makriyannis, A.; Morales-Ruiz, M.; Jiménez, W.
Source: Self-asserted source
0000-0002-2009-5911 via Scopus - Elsevier

Hypoxia and proinflammatory factors upregulate apelin receptor expression in human stellate cells and hepatocytes

Gut
2011 | Journal article
DOI: 10.1136/gut.2010.234690
EID:

2-s2.0-80052585243
Contributors: Melgar-Lesmes, P.; Pauta, M.; Reichenbach, V.; Casals, G.; Ros, J.; Bataller, R.; Morales-Ruiz, M.; Jiménez, W.
Source: Self-asserted source
0000-0002-2009-5911 via Scopus - Elsevier

Apelin mediates the induction of profibrogenic genes in human hepatic stellate cells

Endocrinology
2010 | Journal article
DOI: 10.1210/en.2010-0754
EID:

2-s2.0-78049503283
Contributors: Melgar-Lesmes, P.; Casals, G.; Pauta, M.; Ros, J.; Reichenbach, V.; Bataller, R.; Morales-Ruiz, M.; Jimenez, W.
Source: Self-asserted source
0000-0002-2009-5911 via Scopus - Elsevier

Inactivation of extrahepatic vascular Akt improves systemic hemodynamics and sodium excretion in cirrhotic rats

Journal of Hepatology
2010 | Journal article
DOI: 10.1016/j.jhep.2010.05.031
EID:

2-s2.0-78049458666
Contributors: Fernández-Varo, G.; Melgar-Lesmes, P.; Casals, G.; Pauta, M.; Arroyo, V.; Morales-Ruiz, M.; Ros, J.; Jiménez, W.
Source: Self-asserted source
0000-0002-2009-5911 via Scopus - Elsevier

Ras pathway activation in hepatocellular carcinoma and anti-tumoral effect of combined sorafenib and rapamycin in vivo

Journal of Hepatology
2009 | Journal article
DOI: 10.1016/j.jhep.2009.03.028
EID:

2-s2.0-69949129964
Contributors: Newell, P.; Toffanin, S.; Villanueva, A.; Chiang, D.Y.; Minguez, B.; Cabellos, L.; Savic, R.; Hoshida, Y.; Lim, K.H.; Melgar-Lesmes, P. et al.
Source: Self-asserted source
0000-0002-2009-5911 via Scopus - Elsevier

Vascular endothelial growth factor and angiopoietin-2 play a major role in the pathogenesis of vascular leakage in cirrhotic rats

Gut
2009 | Journal article
DOI: 10.1136/gut.2008.155028
EID:

2-s2.0-58849114178
Contributors: Melgar-Lesmes, P.; Tugues, S.; Ros, J.; Fernández-Varo, G.; Morales-Ruiz, M.; Rodés, J.; Jiménez, W.
Source: Self-asserted source
0000-0002-2009-5911 via Scopus - Elsevier

The hepatic apelin system: A new therapeutic target for liver disease

Hepatology
2008 | Journal article
DOI: 10.1002/hep.22467
EID:

2-s2.0-54449100784
Contributors: Principe, A.; Melgar-Lesmes, P.; Fernández-Varo, G.; del Arbol, L.R.; Ros, J.; Morales-Ruiz, M.; Bernardi, M.; Arroyo, V.; Jiménez, W.
Source: Self-asserted source
0000-0002-2009-5911 via Scopus - Elsevier

Ascites from cirrhotic patients induces angiogenesis through the phosphoinositide 3-kinase/Akt signaling pathway

Journal of Hepatology
2005 | Journal article
DOI: 10.1016/j.jhep.2005.01.035
EID:

2-s2.0-20444410027
Contributors: Morales-Ruiz, M.; Tugues, S.; Cejudo-Martín, P.; Ros, J.; Melgar-Lesmes, P.; Fernández-Llama, P.; Arroyo, V.; Rodés, J.; Jiménez, W.
Source: Self-asserted source
0000-0002-2009-5911 via Scopus - Elsevier

Peer review (1 review for 1 publication/grant)

Review activity for Journal of medicinal chemistry. (1)
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