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Aging, Age-related Diseases, Hypothalamus, Caloric restriction, Ghrelin, NPY, Autophagy, Neurodegeneration, Neuroinflammation, Neurogenesis, Blood-brain barriers, Metabolism, Diabetes

Biography

Célia Aveleira got her BSc degree in Biology in 2002 at the Faculty of Sciences and Technology, University of Coimbra, Portugal. In 2003, she received a FCT Research Fellowship to work at Retinal Dysfunction Group, Centre of Ophthalmology and Vision Sciences, IBILI, Faculty of Medicine, University of Coimbra, in a project entitled “Mechanisms of cell degeneration in diabetic retinopathy”. In 2005, she got a FCT PhD Fellowship to develop her PhD research in the same group. She spent 2 years at the Penn State Hershey Retina Research Group, Department of Cellular and Molecular Physiology, Penn State University College of Medicine, Hershey, Pennsylvania, USA, to develop complementary studies for her PhD. Célia got her PhD degree in Biomedical Sciences at the Faculty of Medicine, University of Coimbra, in 2010. After that, Célia Aveleira became a postdoctoral researcher at the Center for Neuroscience and Cell Biology, University of Coimbra. Her research was focused on the role of caloric restriction mimetics as therapeutics targets to delay the aging process of normal and premature aging diseases, such as Hutchinson-Gilford progeria syndrome (HGPS). In 2011, Célia Aveleira was granted with a FCT Post-Doctoral fellowship to study the potential role of neuropeptide Y (NPY) as a mimetic of caloric restriction to reduce aging and ameliorate age-related diseases. In 2013 she got a position at CNC, as an Invited Scientist under the project “Aging, Stress and Chronic Diseases: From Mechanisms to Therapeutics”, supported by QREN - Mais Centro: Programa Operacional Regional do Centro. In line with her research, Celia was awarded in April 2015 with an Innovator Research Grant as Principal Investigator from Progeria Research Foundation (USA) to study the therapeutic potential of ghrelin to rescue HGPS premature aging phenotype. In January 2017 Célia was enrolled in the FCT Investigator Programme and started her appointment as Assistant Investigator (equivalent to Assistant Professor with no teaching load) at CNC. For the past years, Celia has been working within the Aging and Neuroscience fields, particularly focused on aging mechanisms and how the hypothalamus regulates whole-body aging as well as on the potential of neuroendocrine peptides to delay the aging process of normal and age-related diseases. In April 2022 Celia joined Multidisciplinary Institute of Ageing (MIA-Portugal), University of Coimbra, as an Assistant investigator. Her research has been focused on understanding the mechanisms underlying brain ageing and neurodegenerative diseases. The ultimate goal is to develop novel therapeutic strategies to delay/ameliorate age-related diseases and improve quality of life.
Célia A. Aveleira is the author/co-author of 25 scientific articles (7 as 1st and 3 as senior author; 19 published in Q1 journals, 2275 citations, and h-factor 16 (Scopus). She is also co-author of 2 book chapters. As an important component of the dissemination of her research outputs, she participated in several national and international meetings being an author/coauthor of 138 presentations: 60 oral communications (22 as 1st author and 11 as senior author) and 82 poster presentations (29 as 1st author and 13 as senior author). She has participated in 18 research projects (2 as PI and 1 as Co-PI) and has been responsible for student training and supervision: 5 MSc and 4 BSc students as principal supervisor, 4 PhD (ongoing) and 4 MSc students as co-supervisor, and collaborated in the supervision of 2 PhD, 2 MSc, and 7 undergraduate students. Célia A. Aveleira was granted 13 awards/grants. She has participated as a lecturer in several MSc and PhD programs of the University of Coimbra and other Portuguese Universities and in several academic examining committees of MSc and PhD Thesis. She is a Review Editor of Frontiers in Aging and peer-reviewed in several international journals. In addition to her scientific activity, Célia has also participated in several science communication activities, particularly, in Brain Awareness Week, European Researchers Night, and Ciência Viva summer program, as well as other activities related to science dissemination to high school students and teachers.
In 2020 Celia become a mother of twins and had a career break due to high-risk pregnancy leave and maternity leave which impacted her scientific productivity.

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Activities

Employment (9)

MIA-Portugal, University of Coimbra: Coimbra, PT

2022-04-01 to present | Assistant Investigator
Employment
Source: Self-asserted source
Aveleira CA

Center for Neuroscience and Cell Biology, University of Coimbra: Coimbra, PT

2017-01-01 to 2021-12-31 | Assistant Investigator
Employment
Source: Self-asserted source
Aveleira CA

Center for Neuroscience and Cell Biology, University of Coimbra: Coimbra, PT

2015-10-01 to 2016-12-31 | Post-doc Research Fellow
Employment
Source: Self-asserted source
Aveleira CA

Center for Neuroscience and Cell Biology (CNCB)/Institute for Interdisciplinary Research (IIIUC), University of Coimbra: Coimbra, PT

2013-10-01 to 2015-09-30 | Invited Scientist
Employment
Source: Self-asserted source
Aveleira CA

Center for Neuroscience and Cell Biology, University of Coimbra: Coimbra, PT

2010-04-01 to 2013-09-30 | Post-doc Research Fellow
Employment
Source: Self-asserted source
Aveleira CA

Center of Ophthalmology and Vision Sciences, IBILI, Faculty of Medicine: Coimbra, PT

2005-02-01 to 2010-01-21 | PhD student (FCT fellowship SFRH/BD/18727/2004)
Employment
Source: Self-asserted source
Aveleira CA

Pennsylvania State University: Hershey, US

2007-03 to 2009-12 | Visiting PhD student (Department of Cellular and Molecular Physiology, Penn State College of Medicine)
Employment
Source: Self-asserted source
Aveleira CA

Center of Ophthalmology and Vision Sciences, IBILI, Faculty of Medicine, University of Coimbra: Coimbra, PT

2003-03-01 to 2005-01-31 | Research fellow
Employment
Source: Self-asserted source
Aveleira CA

Department of Medical Genetics, Faculty of Medicine, University of Coimbra: Coimbra, PT

2001-09 to 2002-09 | Undergraduate research trainee
Employment
Source: Self-asserted source
Aveleira CA

Education and qualifications (2)

University of Coimbra: Coimbra, PT

2010-01 | PhD in Biomedical Sciences (Faculty of Medicine)
Education
Source: Self-asserted source
Aveleira CA

University of Coimbra: Coimbra, PT

2002-07 | B.Sc. in Biology (Faculty of Sciences and Technology)
Education
Source: Self-asserted source
Aveleira CA

Funding (21)

Centro de Inovação em Biomedicina e Biotecnologia - Laboratório Associado

2021-01-01 to 2025-12-31 | Grant
Fundação para a Ciência e Tecnologia (Lisbon, PT)
GRANT_NUMBER:

168189UID

Source: Self-asserted source
Aveleira CA via DimensionsWizard
grade
Preferred source (of 2)‎

CIBB (Center for Innovative Biotecnology and Biomedicine) - Institutional Strategic Project

2020-01 to 2023-12 | Contract
N/A (N/A, PT)
GRANT_NUMBER:

UIDB/04539/2020

Source: check_circle
CIÊNCIAVITAE

Ostructive Sleep Apnea early diagnosis as a new strategy to delay ageing

2018-07 to 2021-07 | Contract
Fundação para a Ciência e a Tecnologia (Lisboa, PT)
GRANT_NUMBER:

PTDC/MEC-MCI/29002/2017

Source: check_circle
CIÊNCIAVITAE

NiNjA - New Neuroendocrine Strategy for healthy Aging

2018-06 to 2021-05 | Grant
Fundação para a Ciência e a Tecnologia (Lisbon, PT)
GRANT_NUMBER:

POCI-01-0145-FEDER-030167

Source: Self-asserted source
Aveleira CA
grade
Preferred source (of 2)‎

Ghrelin: a new therapeutic strategy to delay aging through hypothalamic control

2017-01 to 2021-12 | Contract
Fundação para a Ciência e a Tecnologia (Lisboa, PT)
GRANT_NUMBER:

IF/00825/2015

Source: check_circle
CIÊNCIAVITAE

HEALTHY AGING 2020

2017-01 to 2020-12 | Grant
Centro2020 - Programa Operacional Centro 2020 (FEDER/FSE) (Coimbra, PT)
GRANT_NUMBER:

CENTRO-01-0145-FEDER-000012

Source: Self-asserted source
Aveleira CA
grade
Preferred source (of 2)‎

Imaging Gene Therapy in the Brain

2016-06 to 2019-12 | Contract
Fundação para a Ciência e a Tecnologia (Lisboa, PT)
GRANT_NUMBER:

PTDC/BBB-NAN/0932/2014

Source: check_circle
CIÊNCIAVITAE

Ghrelin: a new therapeutic strategy to delay aging through hypothalamic control

2016-01 to 2016-12 | Grant
Fundação para a Ciência e a Tecnologia (Lisboa, PT)
GRANT_NUMBER:

SFRH/BPD/111710/2015

Source: check_circle
CIÊNCIAVITAE

Ghrelin: a novel therapeutic intervention to rescue the phenotype of Hutchinson‐Gilford Progeria Syndrome

2015-04 to 2016-12 | Grant
Progeria Research Foundation (Boston, MA, US)
GRANT_NUMBER: PRF2014-53
Source: Self-asserted source
Aveleira CA
grade
Preferred source (of 2)‎

CNC.IBILI - Institutional strategic project

2015-01 to 2018-12 | Contract
N/A (N/A, PT)
GRANT_NUMBER:

POCI-01-0145-FEDER-007440

Source: check_circle
CIÊNCIAVITAE

Aging, Stress and Chronic Diseases: From Mechanisms to Therapeutics

2013-10 to 2015-09 | Grant
QREN - Mais Centro: Programa Operacional Regional do Centro 2007-2013 (Coimbra, PT)
GRANT_NUMBER:

CENTRO-07-ST24-FEDER-002006

Source: Self-asserted source
Aveleira CA
grade
Preferred source (of 2)‎

Heatlh Sciences (Institutional strategic project)

2013-01 to 2014-12 | Grant
N/A (N/A, PT)
GRANT_NUMBER:

PEst-C/SAU/LA0001/2013e2014

Source: check_circle
CIÊNCIAVITAE

Neuropeptide Y as a caloric restriction mimetic: a new target for aging?

2011-04 to 2013-09 | Grant
Fundação para a Ciência e a Tecnologia (Lisboa, PT)
GRANT_NUMBER:

SFRH/BPD/73942/2010

Source: check_circle
CIÊNCIAVITAE

Heatlh Sciences (Institutional strategic project)

2011-01 to 2012-12 | Grant
N/A (N/A, PT)
GRANT_NUMBER:

PEst-C/SAU/LA0001/2011

Source: check_circle
CIÊNCIAVITAE

Impact of methamphetamine on the blood-brain barrier: unmasking the underlying mechanisms and the role of neuroinflammation

2010-04 to 2013-09 | Contract
Universidade do Algarve Faculdade de Ciências e Tecnologia (Faro, PT)
Source: check_circle
CIÊNCIAVITAE

Caloric restriction increases lifespan: role of neuropeptide Y on autophagy

2010-04 to 2013-07 | Contract
Fundação para a Ciência e a Tecnologia (Lisboa, PT)
GRANT_NUMBER:

PTDC/SAU-FCF/099082/2008

Source: check_circle
CIÊNCIAVITAE

Regulation of AMPA receptors by hyperglycemia in the retina

2007-06 to 2010-12 | Contract
Fundação para a Ciência e a Tecnologia (Lisboa, PT)
GRANT_NUMBER:

PTDC/SAU-NEU/71228/2006

Source: check_circle
CIÊNCIAVITAE

Neuropeptide Y in the retina: Why? What for?

2007-03 to 2010-04 | Grant
Fundação para a Ciência e a Tecnologia, I.P. (Lisboa, PT)
GRANT_NUMBER:

PTDC/SAU-NEU/73119/2006

Source: Self-asserted source
Aveleira CA
grade
Preferred source (of 2)‎

The role of interleukin-1 beta in blood-retinal barrier breakdown in the early stages of Diabetic Retinopathy

2005-02 to 2009-01 | Grant
Fundação para a Ciência e a Tecnologia (Lisboa, PT)
GRANT_NUMBER:

SFRH/BD/18727/2004

Source: check_circle
CIÊNCIAVITAE

Regulation of the expression of the type I IL-1 receptor in the retina

2005-01 to 2005-12 | Grant
Faculdade de Medicina, Universidade de Coimbra (Coimbra, PT)
GRANT_NUMBER:

GAI 10/05

Source: Self-asserted source
Aveleira CA
grade
Preferred source (of 2)‎

Mechanisms of cell degeneration in diabetic retinopathy

2002-10 to 2005-12 | Grant
Fundação para a Ciência e a Tecnologia, I.P. (Lisboa, PT)
GRANT_NUMBER:

POCTI/CBO/38545/2001

Source: Self-asserted source
Aveleira CA
grade
Preferred source (of 2)‎

Works (50 of 103)

Items per page:
Page 1 of 3

Ataxin-2 in the hypothalamus at the crossroads between metabolism and clock genes

Journal of Molecular Endocrinology
2023 | Journal article
EID:

2-s2.0-85143645604

Part of ISSN: 14796813 09525041
Contributors: Carmo-Silva, S.; Ferreira-Marques, M.; Nóbrega, C.; Botelho, M.; Costa, D.; Aveleira, C.A.; Pulst, S.M.; de Almeida, L.P.; Cavadas, C.
Source: Self-asserted source
Aveleira CA via Scopus - Elsevier
grade
Preferred source (of 2)‎

Cellular Senescence: From Mechanisms to Current Biomarkers and Senotherapies

Pharmacological Reviews
2023 | Journal article
EID:

2-s2.0-85163864527

Part of ISSN: 15210081 00316997
Contributors: Lucas, V.; Cavadas, C.; Aveleira, C.A.
Source: Self-asserted source
Aveleira CA via Scopus - Elsevier
grade
Preferred source (of 2)‎

Ghrelin delays premature aging in Hutchinson-Gilford progeria syndrome

Aging Cell
2023 | Journal article
EID:

2-s2.0-85174420928

Part of ISSN: 14749726 14749718
Contributors: Ferreira-Marques, M.; Carvalho, A.; Franco, A.C.; Leal, A.; Botelho, M.; Carmo-Silva, S.; Águas, R.; Cortes, L.; Lucas, V.; Real, A.C. et al.
Source: Self-asserted source
Aveleira CA via Scopus - Elsevier
grade
Preferred source (of 2)‎

Nuclear aging in polyglutamine-induced neurodegeneration

bioRxiv
2023 | Other
EID:

2-s2.0-85165916137

Part of ISSN: 26928205
Contributors: Pereira, D.; Cunha-Santos, J.; Vasconcelos-Ferreira, A.; Duarte-Neves, J.; Onofre, I.; Carmona, V.; Aveleira, C.A.; Lopes, S.M.; Lobo, D.D.; Martins, I.M. et al.
Source: Self-asserted source
Aveleira CA via Scopus - Elsevier
grade
Preferred source (of 2)‎

Skin senescence: mechanisms and impact on whole-body aging

Trends in Molecular Medicine
2022 | Journal article
EID:

2-s2.0-85122623473

Part of ISSN: 1471499X 14714914
Contributors: Franco, A.C.; Aveleira, C.; Cavadas, C.
Source: Self-asserted source
Aveleira CA via Scopus - Elsevier
grade
Preferred source (of 2)‎

PI3K/AKT/MTOR and ERK1/2-MAPK signaling pathways are involved in autophagy stimulation induced by caloric restriction or caloric restriction mimetics in cortical neurons

Aging
2021 | Journal article
EID:

2-s2.0-85103994461

Part of ISSN: 19454589
Contributors: Ferreira-Marques, M.; Carvalho, A.; Cavadas, C.; Aveleira, C.A.
Source: Self-asserted source
Aveleira CA via Scopus - Elsevier
grade
Preferred source (of 2)‎

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Autophagy
2021-02-08 | Journal article
SOURCE-WORK-ID:

cv-prod-id-2362234

Contributors: Klionsky D J; Abdel-Aziz A K; ...; Aveleira C
Source: check_circle
CIÊNCIAVITAE

Caloric Restriction, and Caloric Restriction Mimetics Induce Autophagy In Cortical Neurons Through PI3K/AKT And ERK1/2-MAPK Signaling Pathways

Virtual Keystone eSymposia, Autophagy: Mechanisms and Disease
2020-10 | Conference poster
SOURCE-WORK-ID:

cv-prod-id-2362325

Contributors: Ferreira-Marques, Marisa; Carvalho, André; Botelho, Mariana; Carmo-Silva, Sara; Aveleira, Célia A (651B-75AE-BD02); Cavadas, Cláudia (D413-2E77-4BDE)
Source: check_circle
CIÊNCIAVITAE

Neuropeptide Y Enhances Progerin Clearance and Ameliorates the Senescent Phenotype of Human Hutchinson-Gilford Progeria Syndrome Cells.

The Journals of Gerontology: Series A
2020-02-03 | Journal article
SOURCE-WORK-ID:

cv-prod-id-1465626

Contributors: Aveleira, Célia A; Ferreira-Marques, Marisa; Cortes, Luísa; Valero, Jorge; Pereira, Dina; Pereira de Almeida, Luís; Cavadas, Cláudia
Source: check_circle
CIÊNCIAVITAE

Role of Mitochondrial Dysfunction in Human Obesity.

Handbook of Mitochondrial Dysfunction: a volume in the Evolutionary Cell Biology Series
2019 | Book chapter
SOURCE-WORK-ID:

cv-prod-id-1471708

Contributors: Albuquerque, David; Carmo-Silva, Sara; Álvarez-Vaca D; Aveleira C; Nóbrega, Clévio
Source: check_circle
CIÊNCIAVITAE

A neuroendocrine strategy to slow down the clock on skin aging.

BEB day 2019, University of Coimbra, Coimbra, Portugal
2019-12 | Conference poster
SOURCE-WORK-ID:

cv-prod-id-1644699

Contributors: Franco, Ana Catarina da Silva; Ferreira-Marques, Marisa; Carvalho, André; Carmo-Silva, Sara; Botelho, Mariana; Cavadas, Claudia; Aveleira, Célia
Source: check_circle
CIÊNCIAVITAE

Neuroendocrine peptide as a novel therapeutic strategy to delay skin aging.

Centre of Innovative Biomedicine and Biotechnology (CIBB) Annual Meeting, University of Coimbra, Coimbra, Portugal.
2019-12 | Conference poster
SOURCE-WORK-ID:

cv-prod-id-1604175

Contributors: Franco, Ana Catarina da Silva; Ferreira-Marques, Marisa; Carvalho, André; Carmo-Silva, Sara; Botelho, Mariana; Claudia Cavadas; Aveleira, Célia
Source: check_circle
CIÊNCIAVITAE

Targeting the neuroendocrine system to delay aging phenotype in Progeria.

Centre of Innovative Biomedicine and Biotechnology (CIBB) Annual Meeting, University of Coimbra, Coimbra, Portugal.
2019-12 | Conference poster
SOURCE-WORK-ID:

cv-prod-id-1603771

Contributors: Ferreira-Marques, Marisa; Carvalho, André; Franco, Ana Catarina da Silva; Carmo-Silva, Sara; Botelho, Mariana; Cavadas, Claudia; Aveleira, Célia
Source: check_circle
CIÊNCIAVITAE

Neuroendocrine peptide as a novel strategy to delay aging in HGPS.

1st Annual Meeting in Pharmaceutical Sciences, Faculty of Pharmacy, University of Coimbra, Coimbra, Portugal.
2019-11 | Conference poster
SOURCE-WORK-ID:

cv-prod-id-1604522

Contributors: Ferreira-Marques, Marisa; Carvalho, André; Franco, Ana Catarina da Silva; Carmo-Silva, Sara; Botelho, Mariana; Cavadas, Claudia; Aveleira, Célia
Source: check_circle
CIÊNCIAVITAE

Neuroendocrine peptide as a novel strategy to delay skin aging.

1st Annual Meeting in Pharmaceutical Sciences, Faculty of Pharmacy, University of Coimbra, Coimbra, Portugal.
2019-11 | Conference poster
SOURCE-WORK-ID:

cv-prod-id-1604624

Contributors: Franco, Ana Catarina da Silva; Ferreira-Marques, Marisa; Carvalho, André; Carmo-Silva, Sara; Botelho, Mariana; Cavadas, Claudia; Aveleira, Célia
Source: check_circle
CIÊNCIAVITAE

A new neuroendocrine strategy to delay aging in HGPS.

3rd Molecular Biology of Ageing Meeting, European Research Institute for the Biology of Ageing (ERIBA), University Medical Center Groningen, Groningen, The Netherlands.
2019-10 | Conference poster
SOURCE-WORK-ID:

cv-prod-id-1604737

Contributors: Ferreira-Marques, Marisa; Carvalho, André; Franco, Ana Catarina da Silva; Carmo-Silva, Sara; Botelho, Mariana; Cavadas, Claudia; Aveleira, Célia
Source: check_circle
CIÊNCIAVITAE

Hutchinson-Gilford Progeria Syndrome (HGPS): exploring a neuroendocrine strategy to delay aging.

Ageing: models, mechanisms and therapies Conference, Faculty of Medicine, University of Coimbra, Coimbra, Portugal.
2019-10 | Conference poster
SOURCE-WORK-ID:

cv-prod-id-1605138

Contributors: Ferreira-Marques, Marisa; Carvalho, André; Carmo-Silva, Sara; Botelho, Mariana; Cavadas, Claudia; Aveleira, Célia
Source: check_circle
CIÊNCIAVITAE

Neuropeptide Y enhances progerin clearance and delays cellular senescence in human Hutchinson-Gilford Progeria Syndrome cells.

3rd Molecular Biology of Ageing Meeting, European Research Institute for the Biology of Ageing (ERIBA), University Medical Center Groningen, Groningen, The Netherlands.
2019-10 | Conference poster
SOURCE-WORK-ID:

cv-prod-id-1604675

Contributors: Aveleira, Célia; Ferreira-Marques, Marisa; Cortes, Luísa; Valero, Jorge; Pereira, Dina; Pereira de Almeida, Luis Fernando Morgado; Cavadas, Claudia
Source: check_circle
CIÊNCIAVITAE

Ghrelin as a potential therapeutic strategy to delay skin aging and hair loss in Hutchinson-Gilford Progeria Syndrome.

Ageing: models, mechanisms and therapies Conference, Faculty of Medicine, University of Coimbra, Coimbra, Portugal.
2019-06 | Conference poster
SOURCE-WORK-ID:

cv-prod-id-1605214

Contributors: Franco, Ana Catarina da Silva; Ferreira-Marques, Marisa; Carvalho, André; Carmo-Silva, Sara; Botelho, Mariana; Cavadas, Claudia; Aveleira, Célia
Source: check_circle
CIÊNCIAVITAE

Gut alterations in a mouse model of Progeria.

Ageing: models, mechanisms and therapies Conference, Faculty of Medicine, University of Coimbra, Coimbra, Portugal.
2019-06 | Conference poster
SOURCE-WORK-ID:

cv-prod-id-1605298

Contributors: Ferreira, Inês João Dinis; Ferreira-Marques, Marisa; Carvalho, André; Carmo-Silva, Sara; Botelho, Mariana; Aveleira, Célia; Cavadas, Claudia
Source: check_circle
CIÊNCIAVITAE

Neuropeptide Y ameliorates the aging phenotype of Hutchinson-Gilford Progeria Syndrome cells.

Ageing: models, mechanisms and therapies Conference, Faculty of Medicine, University of Coimbra, Coimbra, Portugal.
2019-06 | Conference poster
SOURCE-WORK-ID:

cv-prod-id-1605103

Contributors: Aveleira, Célia; Ferreira-Marques, Marisa; Cortes, Luísa; Valero, Jorge; Pereira, Dina; Pereira de Almeida, Luis Fernando Morgado; Cavadas, Claudia
Source: check_circle
CIÊNCIAVITAE

Role of mitochondrial dysfunction in human obesity

HANDBOOK OF MITOCHONDRIAL DYSFUNCTION
2019-06-15 | Book chapter
Part of ISBN: 9781138336087
Source: Self-asserted source
Aveleira CA

Elevated Glucose and Interleukin-1 β Differentially Affect Retinal Microglial Cell Proliferation

Mediators of Inflammation
2017 | Journal article
EID:

2-s2.0-85019972449

Contributors: Baptista, F.I.; Aveleira, C.A.; Castilho, Á.F.; Ambrósio, A.F.
Source: Self-asserted source
Aveleira CA via Scopus - Elsevier
grade
Preferred source (of 2)‎

Caloric restriction stimulates autophagy in rat cortical neurons through neuropeptide Y and ghrelin receptors activation

Aging
2016 | Journal article
EID:

2-s2.0-85014143445

Contributors: Ferreira-Marques, M.; Aveleira, C.A.; Carmo-Silva, S.; Botelho, M.; de Almeida, L.P.; Cavadas, C.
Source: Self-asserted source
Aveleira CA via Scopus - Elsevier
grade
Preferred source (of 2)‎

The pathophysiology of defective proteostasis in the hypothalamus - From obesity to ageing

Nature Reviews Endocrinology
2016 | Journal article
EID:

2-s2.0-84978056025

Contributors: Cavadas, C.; Aveleira, C.A.; Souza, G.F.P.; Velloso, L.A.
Source: Self-asserted source
Aveleira CA via Scopus - Elsevier
grade
Preferred source (of 2)‎

Neuropeptide Y1 and Y5 receptors activation stimulate autophagic flux in mouse hypothalamic neurons.

11th NPY-PYY-PP International Meeting
2016-08 | Conference paper
SOURCE-WORK-ID:

cv-prod-id-1607303

Contributors: Botelho, Mariana; Aveleira, Célia; Carmo-Silva, Sara; Pascoal, Jorge; Ferreira-Marques, Marisa; Nóbrega, Clévio; Cortes, Luísa; et al.
Source: check_circle
CIÊNCIAVITAE

Neuropeptide Y rescues the senescent phenotype of human Hutchinson-Gilford Progeria Syndrome cells.

Cell Symposia – Aging and Metabolism, Sitges, Spain.
2016-07 | Conference poster
SOURCE-WORK-ID:

cv-prod-id-1605341

Contributors: Aveleira, Célia; Botelho, Mariana; Cortes, Luísa; Valero, Jorge; Pereira, Dina; Pereira de Almeida, Luis Fernando Morgado; Cavadas, Claudia
Source: check_circle
CIÊNCIAVITAE

Ghrelin enhances progerin clearance and rescues the senescent phenotype of human Hutchinson-Gilford Progeria Syndrome cells.

8th Progeria Research Foundation International Scientific Workshop – Across the Table, Around the Globe, Cambridge, MA, USA.
2016-05 | Conference poster
SOURCE-WORK-ID:

cv-prod-id-1605498

Contributors: Aveleira, Célia; Cortes, Luísa; Ferreira-Marques, Marisa; Leal, Ana; Valero, Jorge; Pereira, Dina; Pereira de Almeida, Luis Fernando Morgado; Cavadas, Claudia
Source: check_circle
CIÊNCIAVITAE

Hypothalamic ataxin-2: a new player in central regulation of regulation of energy balance.

EMBO Workshop – Neural control of metabolism and eating behavior, Cascais, Portugal.
2016-05 | Conference poster
SOURCE-WORK-ID:

cv-prod-id-1605446

Contributors: Carmo-Silva, Sara; Nóbrega, Clévio; Ferreira-Marques, Marisa; Botelho, Mariana; Aveleira, Célia; Pulst, Stefan; Pereira de Almeida, Luis Fernando Morgado; Cavadas, Claudia
Source: check_circle
CIÊNCIAVITAE

Impaired adrenal medullary function in a mouse model of depression induced by unpredictable chronic stress

European Neuropsychopharmacology
2015 | Journal article
EID:

2-s2.0-84943267584

Contributors: Santana, M.M.; Rosmaninho-Salgado, J.; Cortez, V.; Pereira, F.C.; Kaster, M.P.; Aveleira, C.A.; Ferreira, M.; Álvaro, A.R.; Cavadas, C.
Source: Self-asserted source
Aveleira CA via Scopus - Elsevier
grade
Preferred source (of 2)‎

Long-term exposure to high glucose increases the content of several exocytotic proteins and of vesicular GABA transporter in cultured retinal neural cells

Neuroscience Letters
2015 | Journal article
EID:

2-s2.0-84936870832

Contributors: Baptista, F.I.; Castilho, A.F.; Gaspar, J.M.; Liberal, J.T.; Aveleira, C.A.; Ambrósio, A.F.
Source: Self-asserted source
Aveleira CA via Scopus - Elsevier
grade
Preferred source (of 2)‎

Neuropeptide Y rescues the aging phenotype of a mouse model of human premature aging.

XII CNC Annual Meeting, Coimbra, Portugal
2015 | Conference poster
SOURCE-WORK-ID:

cv-prod-id-1644840

Contributors: Aveleira, Célia; Carmo-Silva, Sara; Botelho, Mariana; Ferreira-Marques, Marisa; Nóbrega, Clévio; López-Otín, Carlos; Pereira de Almeida, Luis Fernando Morgado; Cavadas, Claudia
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CIÊNCIAVITAE

Neuropeptide Y stimulates autophagy in hypothalamic neurons

Proceedings of the National Academy of Sciences of the United States of America
2015 | Journal article
EID:

2-s2.0-84926180461

Contributors: Aveleira, C.A.; Botelho, M.; Carmo-Silva, S.; Pascoal, J.F.; Ferreira-Marques, M.; Nóbrega, C.; Cortes, L.; Valero, J.; Sousa-Ferreira, L.; Álvaro, A.R. et al.
Source: Self-asserted source
Aveleira CA via Scopus - Elsevier
grade
Preferred source (of 2)‎

NPY/neuropeptide Y enhances autophagy in the hypothalamus: A mechanism to delay aging?

Autophagy
2015 | Journal article
EID:

2-s2.0-84943781953

Contributors: Aveleira, C.A.; Botelho, M.; Cavadas, C.
Source: Self-asserted source
Aveleira CA via Scopus - Elsevier
grade
Preferred source (of 2)‎

Ataxin-2 in the hypothalamus: a novel regulator of energy balance and metabolism.

XIII CNC Annual Meeting, Coimbra, Portugal.
2015-12 | Conference poster
SOURCE-WORK-ID:

cv-prod-id-1605996

Contributors: Carmo-Silva, Sara; Nóbrega, Clévio; Ferreira-Marques, Marisa; Botelho, Mariana; Aveleira, Célia; Álvaro, Ana Rita ; Pulst, Stefan; Pereira de Almeida, Luis Fernando Morgado; Cavadas, Claudia
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CIÊNCIAVITAE

Neuropeptide Y rescues the senescent phenotype of human Hutchinson-Gilford Progeria Syndrome cells.

XIII CNC Annual Meeting, Coimbra, Portugal.
2015-12 | Conference poster
SOURCE-WORK-ID:

cv-prod-id-1605673

Contributors: Aveleira, Célia; Cortes, Luísa; Pereira, Joana; Leal, Ana; Pereira, Dina; Valero, Jorge; Pereira de Almeida, Luis Fernando Morgado; Cavadas, Claudia
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CIÊNCIAVITAE

Neuropeptide Y1 and Y5 receptors activation stimulate autophagic flux in mouse hypothalamic neurons.

11th NPY-PYY-PP International Meeting, Leipzig, Germany.
2015-08 | Conference poster
SOURCE-WORK-ID:

cv-prod-id-1606099

Contributors: Botelho, Mariana; Aveleira, Célia; Carmo-Silva, Sara; Pascoal, Jorge; Ferreira-Marques, Marisa; Nóbrega, Clévio; Cortes, Luísa; et al.
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CIÊNCIAVITAE

Autophagy in the hypothalamus: the role of Neuropeptide Y.

9th IBRO World Congress on Neuroscience, Rio de Janeiro, Brazil.
2015-07 | Conference poster
SOURCE-WORK-ID:

cv-prod-id-1606145

Contributors: Botelho, Mariana; Aveleira, Célia; Carmo-Silva, Sara; Pascoal, Jorge; Ferreira-Marques, Marisa; Nóbrega, Clévio; Cortes, Luísa; et al.
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CIÊNCIAVITAE

Impact of hypothalamic ataxin-2 on energy balance and metabolic profile.

9th IBRO World Congress on Neuroscience, Rio de Janeiro, Brazil.
2015-07 | Conference poster
SOURCE-WORK-ID:

cv-prod-id-1606251

Contributors: Carmo-Silva, Sara; Nóbrega, Clévio; Ferreira-Marques, Marisa; Botelho, Mariana; Álvaro, Ana Rita ; Aveleira, Célia; Pulst, Stefan; Pereira de Almeida, Luis Fernando Morgado; Cavadas, Claudia
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CIÊNCIAVITAE

Neuropeptide Y enhances progerin clearance and rescues the senescent phenotype of human Hutchinson-Gilford Progeria Syndrome fibroblasts.

The Translational Science of Aging: From Functional Pathways to Interventions Gordon Research Conference on Biology of Aging, Sunday River, Newry, USA.
2015-07 | Conference poster
SOURCE-WORK-ID:

cv-prod-id-1606445

Contributors: Aveleira, Célia; Cortes, Luísa; Valero, Jorge; Pereira, Dina; Pereira de Almeida, Luis Fernando Morgado; Cavadas, Claudia
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CIÊNCIAVITAE

Neuropeptide Y rescues the aging phenotype of a mouse model of human premature aging.

The Translational Science of Aging: From Functional Pathways to Interventions Gordon Research Conference on Biology of Aging, Sunday River, Newry, USA.
2015-07 | Conference poster
SOURCE-WORK-ID:

cv-prod-id-1606520

Contributors: Aveleira, Célia; Carmo-Silva, Sara; Botelho, Mariana; Ferreira-Marques, Marisa; Nóbrega, Clévio; López-Ótin, Carlos; Pereira de Almeida, Luis Fernando Morgado; Cavadas, Claudia
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CIÊNCIAVITAE

Hypothalamic ataxin-2 regulates energy balance and metabolism.

Neural Control of Metabolic Physiology and Diseases Keystone Symposia on Molecular and Cellular Biology, Snowbird, Utah, USA.
2015-04 | Conference poster
SOURCE-WORK-ID:

cv-prod-id-1607876

Contributors: Carmo-Silva, Sara; Nóbrega, Clévio; Botelho, Mariana; Ferreira-Marques, Marisa; Aveleira, Célia; Pulst, Stefan; Pereira de Almeida, Luis Fernando Morgado; Cavadas, Claudia
Source: check_circle
CIÊNCIAVITAE

Alterations in phospholipidomic profile in the brain of mouse model of depression induced by chronic unpredictable stress

Neuroscience
2014 | Journal article
EID:

2-s2.0-84901323540

Contributors: Faria, R.; Santana, M.M.; Aveleira, C.A.; Simões, C.; Maciel, E.; Melo, T.; Santinha, D.; Oliveira, M.M.; Peixoto, F.; Domingues, P. et al.
Source: Self-asserted source
Aveleira CA via Scopus - Elsevier
grade
Preferred source (of 2)‎

Fluoxetine induces proliferation and inhibits differentiation of hypothalamic neuroprogenitor cells in vitro

PLoS ONE
2014 | Journal article
EID:

2-s2.0-84897138484

Contributors: Sousa-Ferreira, L.; Aveleira, C.; Botelho, M.; Álvaro, A.R.; Pereira De Almeida, L.; Cavadas, C.
Source: Self-asserted source
Aveleira CA via Scopus - Elsevier

A differential effect of neuropeptide y and caloric restriction on hypothalamus neurogenesis.

XII CNC Annual Meeting, Coimbra, Portugal
2014-12 | Conference poster
SOURCE-WORK-ID:

cv-prod-id-1644883

Contributors: Álvaro, Ana Rita ; Aveleira, Célia; Martins, Helena; Sousa-Ferreira, Lígia; Botelho, Mariana; Carmo-Silva, Sara; Cavadas, Claudia
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CIÊNCIAVITAE

Neuropeptide Y stimulates autophagy in hypothalamic neurons.

FENS Forum 2014, Milan, Italy
2014-07 | Conference poster
SOURCE-WORK-ID:

cv-prod-id-1645077

Contributors: Botelho, Mariana; Aveleira, Célia; Pascoal, Jorge; Carmo-Silva, Sara; Nóbrega, Clévio; Cortes, Luísa; Valero, Jorge; et al.
Source: check_circle
CIÊNCIAVITAE

Beclin 1 mitigates motor and neuropathological deficits in genetic mouse models of Machado-Joseph disease

Brain
2013 | Journal article
EID:

2-s2.0-84879899999

Contributors: Nascimento-Ferreira, I.; Nóbrega, C.; Vasconcelos-Ferreira, A.; Onofre, I.; Albuquerque, D.; Aveleira, C.; Hirai, H.; Déglon, N.; Pereira De Almeida, L.
Source: Self-asserted source
Aveleira CA via Scopus - Elsevier
grade
Preferred source (of 2)‎

Chronic Unpredictable Stress Induces Catecholaminergic System Changes in Mouse Adrenal Gland

Catecholamine Research in the 21st Century: Abstracts and Graphical Abstracts, 10th International Catecholamine Symposium, 2012
2013 | Book
EID:

2-s2.0-84902053928

Contributors: Santana, M.M.; Cortez, V.; Aveleira, C.; Kaster, M.; Rosmaninho-Salgado, J.; Cavadas, C.
Source: Self-asserted source
Aveleira CA via Scopus - Elsevier
grade
Preferred source (of 2)‎

Neuropeptide Y receptors Y<inf>1</inf> and Y<inf>2</inf> are present in neurons and glial cells in rat retinal cells in culture

Investigative Ophthalmology and Visual Science
2013 | Journal article
EID:

2-s2.0-84874719907

Contributors: Santos-Carvalho, A.; Aveleira, C.A.; Elvas, F.; Ambrósio, A.F.; Cavadas, C.
Source: Self-asserted source
Aveleira CA via Scopus - Elsevier
grade
Preferred source (of 2)‎

Effects of high glucose and interleukin-1ß in the different retinal neural cells in culture.

European Retina Meeting 2013, Alicante, Spain
2013-10 | Conference poster
SOURCE-WORK-ID:

cv-prod-id-1645127

Contributors: Ambrósio, António F.; Baptista, Filipa I.; Aveleira, Célia; Castilho, Áurea F.; Fernandes, Carolina; Simões, Núria
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CIÊNCIAVITAE
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