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University of Zurich: Zurich, CH

(Dept. Biochemistry)
Employment
Source: Self-asserted source
Raimund Dutzler

Works (50 of 71)

Items per page:
Page 1 of 2

Heteromeric LRRC8 channel assemblies and their impact on channel activity

Biophysical journal
2023 | Journal article
EID:

2-s2.0-85148055802

Part of ISSN: 15420086
Contributors: Lehmann, E.F.; Rutz, S.; Deneka, D.; Dittmann, A.; Sawicka, M.; Dutzler, R.
Source: Self-asserted source
Raimund Dutzler via Scopus - Elsevier

Structure of a volume-regulated heteromeric LRRC8A/C channel

Nature Structural and Molecular Biology
2023 | Journal article
EID:

2-s2.0-85143971971

Part of ISSN: 15459985 15459993
Contributors: Rutz, S.; Deneka, D.; Dittmann, A.; Sawicka, M.; Dutzler, R.
Source: Self-asserted source
Raimund Dutzler via Scopus - Elsevier

Structures of ferroportin in complex with its specific inhibitor vamifeport

eLife
2023 | Journal article
EID:

2-s2.0-85150671030

Part of ISSN: 2050084X
Contributors: Lehmann, E.F.; Liziczai, M.; Drożdżyk, K.; Altermatt, P.; Langini, C.; Manolova, V.; Sundstrom, H.; Dürrenberger, F.; Dutzler, R.; Manatschal, C.
Source: Self-asserted source
Raimund Dutzler via Scopus - Elsevier

Inhibition mechanism of the chloride channel TMEM16A by the pore blocker 1PBC

ResearchSquare
2022 | Other
EID:

2-s2.0-85134137305

Contributors: Dutzler, R.; Lam, A.K.M.; Rutz, S.
Source: Self-asserted source
Raimund Dutzler via Scopus - Elsevier

Inhibition mechanism of the chloride channel TMEM16A by the pore blocker 1PBC

Nature Communications
2022 | Journal article
EID:

2-s2.0-85130357764

Part of ISSN: 20411723
Contributors: Lam, A.K.M.; Rutz, S.; Dutzler, R.
Source: Self-asserted source
Raimund Dutzler via Scopus - Elsevier

Regulators of cell volume: The structural and functional properties of anion channels of the LRRC8 family

Current Opinion in Structural Biology
2022 | Journal article
EID:

2-s2.0-85129044886

Part of ISSN: 1879033X 0959440X
Contributors: Sawicka, M.; Dutzler, R.
Source: Self-asserted source
Raimund Dutzler via Scopus - Elsevier

Structural and functional properties 1 of a magnesium transporter of the SLC11/NRAMP family

eLife
2022 | Journal article
EID:

2-s2.0-85124030483

Part of ISSN: 2050084X
Contributors: Ramanadane, K.; Straub, M.S.; Dutzler, R.; Manatschal, C.
Source: Self-asserted source
Raimund Dutzler via Scopus - Elsevier

Structural and functional properties of a plant NRAMP related aluminum transporter

bioRxiv
2022 | Other
EID:

2-s2.0-85147157557

Part of ISSN: 26928205
Contributors: Ramanadane, K.; Liziczai, M.; Markovic, D.; Straub, M.S.; Rosalen, G.T.; Udovcic, A.; Dutzler, R.; Manatschal, C.
Source: Self-asserted source
Raimund Dutzler via Scopus - Elsevier

Structural basis for the activation of the lipid scramblase TMEM16F

Nature Communications
2022 | Journal article
EID:

2-s2.0-85141384641

Part of ISSN: 20411723
Contributors: Arndt, M.; Alvadia, C.; Straub, M.S.; Clerico Mosina, V.; Paulino, C.; Dutzler, R.
Source: Self-asserted source
Raimund Dutzler via Scopus - Elsevier

Structure of a volume-regulated heteromeric LRRC8A/C channel

bioRxiv
2022 | Other
EID:

2-s2.0-85140782470

Part of ISSN: 26928205
Contributors: Rutz, S.; Deneka, D.; Dittmann, A.; Sawicka, M.; Dutzler, R.
Source: Self-asserted source
Raimund Dutzler via Scopus - Elsevier

Structures of ferroportin in complex with its specific inhibitor vamifeport

bioRxiv
2022 | Other
EID:

2-s2.0-85141129679

Part of ISSN: 26928205
Contributors: Lehmann, E.F.; Liziczai, M.; Drożdżyk, K.; Altermatt, P.; Manolova, V.; Sundstrom, H.; Dürrenberger, F.; Dutzler, R.; Manatschal, C.
Source: Self-asserted source
Raimund Dutzler via Scopus - Elsevier

The Structural Basis for Metal Ion Transport in the SLC11/NRAMP Family

Chimia
2022 | Journal article
EID:

2-s2.0-85147782245

Part of ISSN: 00094293
Contributors: Manatschal, C.; Dutzler, R.
Source: Self-asserted source
Raimund Dutzler via Scopus - Elsevier

Allosteric modulation of LRRC8 channels by targeting their cytoplasmic domains

Nature Communications
2021 | Journal article
EID:

2-s2.0-85115213352

Part of ISSN: 20411723
Contributors: Deneka, D.; Rutz, S.; Hutter, C.A.J.; Seeger, M.A.; Sawicka, M.; Dutzler, R.
Source: Self-asserted source
Raimund Dutzler via Scopus - Elsevier

Cryo-EM structures of the Caspase activated protein XKR9 involved in apoptotic lipid scrambling

bioRxiv
2021 | Other
EID:

2-s2.0-85109021819

Part of ISSN: 26928205
Contributors: Straub, M.S.; Alvadia, C.; Sawicka, M.; Dutzler, R.
Source: Self-asserted source
Raimund Dutzler via Scopus - Elsevier

Cryo-em structures of the caspase-activated protein xkr9 involved in apoptotic lipid scrambling

eLife
2021 | Journal article
EID:

2-s2.0-85111461958

Part of ISSN: 2050084X
Contributors: Straub, M.S.; Alvadia, C.; Sawicka, M.; Dutzler, R.
Source: Self-asserted source
Raimund Dutzler via Scopus - Elsevier

Cryo-EM structures of the TTYH family reveal a novel architecture for lipid interactions

Nature Communications
2021 | Journal article
EID:

2-s2.0-85112686879

Part of ISSN: 20411723
Contributors: Sukalskaia, A.; Straub, M.S.; Deneka, D.; Sawicka, M.; Dutzler, R.
Source: Self-asserted source
Raimund Dutzler via Scopus - Elsevier

Gating the pore of the calcium-activated chloride channel TMEM16A

Nature Communications
2021 | Journal article
EID:

2-s2.0-85100545548

Part of ISSN: 20411723
Contributors: Lam, A.K.M.; Rheinberger, J.; Paulino, C.; Dutzler, R.
Source: Self-asserted source
Raimund Dutzler via Scopus - Elsevier

Mechanism of pore opening in the calcium-activated chloride channel TMEM16A

Nature Communications
2021 | Journal article
EID:

2-s2.0-85100544098

Part of ISSN: 20411723
Contributors: Lam, A.K.M.; Dutzler, R.
Source: Self-asserted source
Raimund Dutzler via Scopus - Elsevier

Structural and functional properties of a magnesium transporter of the SLC11/NRAMP family

bioRxiv
2021 | Other
EID:

2-s2.0-85119498056

Part of ISSN: 26928205
Contributors: Ramanadane, K.; Straub, M.S.; Dutzler, R.; Manatschal, C.
Source: Self-asserted source
Raimund Dutzler via Scopus - Elsevier

Alternative chloride transport pathways as pharmacological targets for the treatment of cystic fibrosis

Journal of Cystic Fibrosis
2020 | Journal article
EID:

2-s2.0-85074436556

Part of ISSN: 18735010 15691993
Contributors: Quesada, R.; Dutzler, R.
Source: Self-asserted source
Raimund Dutzler via Scopus - Elsevier

Cryo-EM structures and functional properties of calhm channels of the human placenta

eLife
2020 | Journal article
EID:

2-s2.0-85085265172

Part of ISSN: 2050084X
Contributors: Drożdżyk, K.; Sawicka, M.; Bahamonde-Santos, M.-I.; Jonas, Z.; Deneka, D.; Albrecht, C.; Dutzler, R.
Source: Self-asserted source
Raimund Dutzler via Scopus - Elsevier

Cryo-EM structures and functional properties of CALHM channels of the human placenta

bioRxiv
2020 | Other
EID:

2-s2.0-85098831908

Part of ISSN: 26928205
Contributors: Drożdżyk, K.; Sawicka, M.; Santos, M.-I.B.; Zaugg, J.; Deneka, D.; Albrecht, C.; Dutzler, R.
Source: Self-asserted source
Raimund Dutzler via Scopus - Elsevier

Cryo-EM structures and functional characterization of murine Slc26a9 reveal mechanism of uncoupled chloride transport

eLife
2019 | Journal article
EID:

2-s2.0-85070469907

Part of ISSN: 2050084X
Contributors: Walter, J.D.; Sawicka, M.; Dutzler, R.
Source: Self-asserted source
Raimund Dutzler via Scopus - Elsevier

Cryo-EM structures and functional characterization of the murine lipid scramblase TMEM16F

eLife
2019 | Journal article
EID:

2-s2.0-85062865630

Part of ISSN: 2050084X
Contributors: Alvadia, C.; Lim, N.K.; Mosina, V.C.; Oostergetel, G.T.; Dutzler, R.; Paulino, C.
Source: Self-asserted source
Raimund Dutzler via Scopus - Elsevier

Mechanistic basis of the inhibition of slc11/nramp-mediated metal ion transport by bis-isothiourea substituted compounds

eLife
2019 | Journal article
EID:

2-s2.0-85077544093

Part of ISSN: 2050084X
Contributors: Manatschal, C.; Pujol-Giménez, J.; Poirier, M.; Reymond, J.-L.; Hediger, M.A.; Dutzler, R.
Source: Self-asserted source
Raimund Dutzler via Scopus - Elsevier

Stepwise activation mechanism of the scramblase nhtmem16 revealed by cryo- em

eLife
2019 | Journal article
EID:

2-s2.0-85062846849

Part of ISSN: 2050084X
Contributors: Kalienkova, V.; Mosina, V.C.; Bryner, L.; Oostergetel, G.T.; Dutzler, R.; Paulino, C.
Source: Self-asserted source
Raimund Dutzler via Scopus - Elsevier

Calcium-dependent electrostatic control of anion access to the pore of the calcium-activated chloride channel TMEM16A

eLife
2018 | Journal article
EID:

2-s2.0-85055077330

Part of ISSN: 2050084X
Contributors: Lam, A.K.M.; Dutzler, R.
Source: Self-asserted source
Raimund Dutzler via Scopus - Elsevier

Cryo-EM structures and functional characterization of the lipid scramblase TMEM16F

bioRxiv
2018 | Other
EID:

2-s2.0-85095635130

Part of ISSN: 26928205
Contributors: Alvadia, C.; Lim, N.K.; Mosina, V.C.; Oostergetel, G.T.; Dutzler, R.; Paulino, C.
Source: Self-asserted source
Raimund Dutzler via Scopus - Elsevier

Stepwise activation mechanism of the scramblase nhTMEM16 revealed by cryo-EM

bioRxiv
2018 | Other
EID:

2-s2.0-85095645847

Part of ISSN: 26928205
Contributors: Kalienkova, V.; Mosina, V.C.; Bryner, L.; Oostergetel, G.T.; Dutzler, R.; Paulino, C.
Source: Self-asserted source
Raimund Dutzler via Scopus - Elsevier

Structure of a volume-regulated anion channel of the LRRC8 family

Nature
2018 | Journal article
EID:

2-s2.0-85048498326

Part of ISSN: 14764687 00280836
Contributors: Deneka, D.; Sawicka, M.; Lam, A.K.M.; Paulino, C.; Dutzler, R.
Source: Self-asserted source
Raimund Dutzler via Scopus - Elsevier

Activation mechanism of the calcium-activated chloride channel TMEM16A revealed by cryo-EM

Nature
2017 | Journal article
EID:

2-s2.0-85040008006

Part of ISSN: 14764687 00280836
Contributors: Paulino, C.; Kalienkova, V.; Lam, A.K.M.; Neldner, Y.; Dutzler, R.
Source: Self-asserted source
Raimund Dutzler via Scopus - Elsevier

Generation and Characterization of Anti-VGLUT Nanobodies Acting as Inhibitors of Transport

Biochemistry
2017 | Journal article
EID:

2-s2.0-85026639640

Part of ISSN: 15204995 00062960
Contributors: Schenck, S.; Kunz, L.; Sahlender, D.; Pardon, E.; Geertsma, E.R.; Savtchouk, I.; Suzuki, T.; Neldner, Y.; Štefanić, S.; Steyaert, J. et al.
Source: Self-asserted source
Raimund Dutzler via Scopus - Elsevier

Structural and mechanistic basis of proton-coupled metal ion transport in the SLC11/NRAMP family

Nature Communications
2017 | Journal article
EID:

2-s2.0-85008675507

Part of ISSN: 20411723
Contributors: Ehrnstorfer, I.A.; Manatschal, C.; Arnold, F.M.; Laederach, J.; Dutzler, R.
Source: Self-asserted source
Raimund Dutzler via Scopus - Elsevier

Structural basis for anion conduction in the calcium-activated chloride channel TMEM16A

eLife
2017 | Journal article
EID:

2-s2.0-85020482426

Part of ISSN: 2050084X
Contributors: Paulino, C.; Neldner, Y.; Lam, A.K.M.; Kalienkova, V.; Brunner, J.D.; Schenck, S.; Dutzler, R.
Source: Self-asserted source
Raimund Dutzler via Scopus - Elsevier

Erratum: Structure of a prokaryotic fumarate transporter reveals the architecture of the SLC26 family (Nature Structural and Molecular Biology (2015) 22 (803-808))

Nature Structural and Molecular Biology
2016 | Journal article
EID:

2-s2.0-84966378361

Part of ISSN: 15459985 15459993
Contributors: Geertsma, E.R.; Chang, Y.-N.; Shaik, F.R.; Neldner, Y.; Pardon, E.; Steyaert, J.; Dutzler, R.
Source: Self-asserted source
Raimund Dutzler via Scopus - Elsevier

Independent activation of ion conduction pores in the double-barreled calcium-activated chloride channel TMEM16A

Journal of General Physiology
2016 | Journal article
EID:

2-s2.0-84995920367

Part of ISSN: 15407748 00221295
Contributors: Lim, N.K.; Lam, A.K.M.; Dutzler, R.
Source: Self-asserted source
Raimund Dutzler via Scopus - Elsevier

Signal Transduction at the Domain Interface of Prokaryotic Pentameric Ligand-Gated Ion Channels

PLoS Biology
2016 | Journal article
EID:

2-s2.0-84962164539

Part of ISSN: 15457885 15449173
Contributors: Bertozzi, C.; Zimmermann, I.; Engeler, S.; Hilf, R.J.C.; Dutzler, R.
Source: Self-asserted source
Raimund Dutzler via Scopus - Elsevier

Structural basis for phospholipid scrambling in the TMEM16 family

Current Opinion in Structural Biology
2016 | Journal article
EID:

2-s2.0-84973330914

Part of ISSN: 1879033X 0959440X
Contributors: Brunner, J.D.; Schenck, S.; Dutzler, R.
Source: Self-asserted source
Raimund Dutzler via Scopus - Elsevier

Structure of a prokaryotic fumarate transporter reveals the architecture of the SLC26 family

Nature Structural and Molecular Biology
2015 | Journal article
EID:

2-s2.0-84943390515

Part of ISSN: 15459985 15459993
Contributors: Geertsma, E.R.; Chang, Y.-N.; Shaik, F.R.; Neldner, Y.; Pardon, E.; Steyaert, J.; Dutzler, R.
Source: Self-asserted source
Raimund Dutzler via Scopus - Elsevier

Crystal structure of a SLC11 (NRAMP) transporter reveals the basis for transition-metal ion transport

Nature Structural and Molecular Biology
2014 | Journal article
EID:

2-s2.0-84908885748

Part of ISSN: 15459985 15459993
Contributors: Ehrnstorfer, I.A.; Geertsma, E.R.; Pardon, E.; Steyaert, J.; Dutzler, R.
Source: Self-asserted source
Raimund Dutzler via Scopus - Elsevier

X-ray structure of a calcium-activated TMEM16 lipid scramblase

Nature
2014 | Journal article
EID:

2-s2.0-84918807150

Part of ISSN: 14764687 00280836
Contributors: Brunner, J.D.; Lim, N.K.; Schenck, S.; Duerst, A.; Dutzler, R.
Source: Self-asserted source
Raimund Dutzler via Scopus - Elsevier

Functional characterization of a CIC transporter by solid-supported membrane electrophysiology

Journal of General Physiology
2013 | Journal article
EID:

2-s2.0-84878651582

Part of ISSN: 00221295 15407748
Contributors: Garcia-Celma, J.; Szydelko, A.; Dutzler, R.
Source: Self-asserted source
Raimund Dutzler via Scopus - Elsevier

Inhibition of the Prokaryotic Pentameric Ligand-Gated Ion Channel ELIC by Divalent Cations

PLoS Biology
2012 | Journal article
EID:

2-s2.0-84870266525

Part of ISSN: 15449173 15457885
Contributors: Zimmermann, I.; Marabelli, A.; Bertozzi, C.; Sivilotti, L.G.; Dutzler, R.
Source: Self-asserted source
Raimund Dutzler via Scopus - Elsevier

A versatile and efficient high-throughput cloning tool for structural biology

Biochemistry
2011 | Journal article
EID:

2-s2.0-79953845449

Part of ISSN: 00062960 15204995
Contributors: Geertsma, E.R.; Dutzler, R.
Source: Self-asserted source
Raimund Dutzler via Scopus - Elsevier

Ligand activation of the Prokaryotic Pentameric ligand-gated ion channel ELIC

PLoS Biology
2011 | Journal article
EID:

2-s2.0-79959775185

Part of ISSN: 15449173 15457885
Contributors: Zimmermann, I.; Dutzler, R.
Source: Self-asserted source
Raimund Dutzler via Scopus - Elsevier

Channels and transporters

Chimia
2010 | Journal article
EID:

2-s2.0-77957771524

Part of ISSN: 00094293
Contributors: Dutzler, R.; Ernst, B.; Hediger, M.A.; Keppler, D.; Mohr, P.; Neidhart, W.; Märki, H.P.
Source: Self-asserted source
Raimund Dutzler via Scopus - Elsevier

Structural basis of open channel block in a prokaryotic pentameric ligand-gated ion channel

Nature Structural and Molecular Biology
2010 | Journal article
EID:

2-s2.0-78549271990

Part of ISSN: 15459993 15459985
Contributors: Hilf, R.J.C.; Bertozzi, C.; Zimmermann, I.; Reiter, A.; Trauner, D.; Dutzler, R.
Source: Self-asserted source
Raimund Dutzler via Scopus - Elsevier

A prokaryotic perspective on pentameric ligand-gated ion channel structure

Current Opinion in Structural Biology
2009 | Journal article
EID:

2-s2.0-69249088472

Part of ISSN: 0959440X
Contributors: Hilf, R.J.; Dutzler, R.
Source: Self-asserted source
Raimund Dutzler via Scopus - Elsevier

Structure of a potentially open state of a proton-activated pentameric ligand-gated ion channel

Nature
2009 | Journal article
EID:

2-s2.0-58149242730

Part of ISSN: 14764687 00280836
Contributors: Hilf, R.J.C.; Dutzler, R.
Source: Self-asserted source
Raimund Dutzler via Scopus - Elsevier

X-ray Structure of the C-Terminal Domain of a Prokaryotic Cation-Chloride Cotransporter

Structure
2009 | Journal article
EID:

2-s2.0-64049117335

Part of ISSN: 09692126
Contributors: Warmuth, S.; Zimmermann, I.; Dutzler, R.
Source: Self-asserted source
Raimund Dutzler via Scopus - Elsevier
Items per page:
Page 1 of 2

Peer review (13 reviews for 7 publications/grants)

Review activity for eLife (1)
Review activity for EMBO journal. (2)
Review activity for Nature (2)
Review activity for Nature chemical biology. (1)
Review activity for Nature communications (4)
Review activity for Nature methods. (1)
Review activity for Nature structural & molecular biology. (2)