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Employment (1)

Tianjin Medical University Cancer Institute and Hospital: Tianjin, CN

2017-02-01 to present
Employment
Source: Self-asserted source
Xiangchun Li

Education and qualifications (2)

Chinese University of Hong Kong: New Territories, HK

2012-08-01 to 2016-12-01 | PhD
Education
Source: Self-asserted source
Xiangchun Li

Huazhong University of Science and Technology: Wuhan, Hubei, CN

2006-09-01 to 2010-07-01
Education
Source: Self-asserted source
Xiangchun Li

Works (27)

Generative pretraining from large-scale transcriptomes for single-cell deciphering

iScience
2023-05 | Journal article
DOI: 10.1016/j.isci.2023.106536
Part of ISSN: 2589-0042
Contributors: Hongru Shen; Jilei Liu; Jiani Hu; Xilin Shen; Chao Zhang; Dan Wu; Mengyao Feng; Meng Yang; Yang Li; Yichen Yang et al.
Source: Self-asserted source
Xiangchun Li

A single-cell analysis reveals tumor heterogeneity and immune environment of acral melanoma

Nature Communications
2022-11-25 | Journal article | Author
DOI: 10.1038/s41467-022-34877-3
Part of ISSN: 2041-1723
Contributors: Zhang Chao; Hongru Shen; Tielong Yang; Ting Li; Xinyue Liu; Jin Wang; Zhichao Liao; Junqiang Wei; Jia Lu; Haotian Liu et al.
Source: Self-asserted source
Xiangchun Li

Scalable batch-correction approach for integrating large-scale single-cell transcriptomes

Briefings in Bioinformatics
2022-09-20 | Journal article | Author
DOI: 10.1093/bib/bbac327
Part of ISSN: 1467-5463
Part of ISSN: 1477-4054
Contributors: Xilin Shen; Hongru Shen; Dan Wu; Mengyao Feng; Jiani Hu; Jilei Liu; Yichen Yang; Meng Yang; Yang Li; Lei Shi et al.
Source: Self-asserted source
Xiangchun Li

Deep learning to diagnose Hashimoto’s thyroiditis from sonographic images

Nature Communications
2022-06-29 | Journal article | Author
DOI: 10.1038/s41467-022-31449-3
Part of ISSN: 2041-1723
Contributors: Qiang Zhang; Sheng Zhang; Yi Pan; Lin Sun; Jianxin Li; Yu Qiao; Jing Zhao; Xiaoqing Wang; Yixing Feng; Yanhui Zhao et al.
Source: Self-asserted source
Xiangchun Li

A universal approach for integrating super large-scale single-cell transcriptomes by exploring gene rankings

Briefings in Bioinformatics
2022-01-20 | Journal article
DOI: 10.1093/bib/bbab573
Part of ISSN: 1467-5463
Part of ISSN: 1477-4054
Source: Self-asserted source
Xiangchun Li

Improved diagnosis of thyroid cancer aided with deep learning applied to sonographic text reports: a retrospective, multi-cohort, diagnostic study

Cancer Biology and Medicine
2021 | Journal article
DOI: 10.20892/j.issn.2095-3941.2020.0509
Part of ISSN: 2095-3941
Source: Self-asserted source
Xiangchun Li

Miscell: An efficient self-supervised learning approach for dissecting single-cell transcriptome

iScience
2021-11 | Journal article
DOI: 10.1016/j.isci.2021.103200
Part of ISSN: 2589-0042
Source: Self-asserted source
Xiangchun Li

Transcriptomic Analysis Identified Two Subtypes of Brain Tumor Characterized by Distinct Immune Infiltration and Prognosis

Frontiers in Oncology
2021-10-15 | Journal article
DOI: 10.3389/fonc.2021.734407
Part of ISSN: 2234-943X
Source: Self-asserted source
Xiangchun Li

Development of an AI system for accurately diagnose hepatocellular carcinoma from computed tomography imaging data

British Journal of Cancer
2021-10-12 | Journal article
DOI: 10.1038/s41416-021-01511-w
Part of ISSN: 0007-0920
Part of ISSN: 1532-1827
Source: Self-asserted source
Xiangchun Li
grade
Preferred source (of 2)‎

Diagnostic evaluation of a deep learning model for optical diagnosis of colorectal cancer

Nature Communications
2020-12 | Journal article
DOI: 10.1038/s41467-020-16777-6
Part of ISSN: 2041-1723
Source: Self-asserted source
Xiangchun Li

Analysis of immune-related signatures of lung adenocarcinoma identified two distinct subtypes: implications for immune checkpoint blockade therapy

Aging
2020-02-24 | Journal article
DOI: 10.18632/aging.102814
Part of ISSN: 1945-4589
Source: Self-asserted source
Xiangchun Li

The new identified biomarkers determine sensitivity to immune check-point blockade therapies in melanoma

OncoImmunology
2019-08-03 | Journal article
DOI: 10.1080/2162402x.2019.1608132
Part of ISSN: 2162-402X
Source: Self-asserted source
Xiangchun Li

Diagnosis of thyroid cancer using deep convolutional neural network models applied to sonographic images: a retrospective, multicohort, diagnostic study.

The Lancet. Oncology
2018-12-21 | Journal article
DOI: 10.1016/s1470-2045(18)30762-9
PMID: 30583848
Source: Self-asserted source
Xiangchun Li

Association of MUC16 Mutation With Tumor Mutation Load and Outcomes in Patients With Gastric Cancer.

JAMA oncology
2018-12-01 | Journal article
DOI: 10.1001/jamaoncol.2018.2805
PMID: 30098163
Source: Self-asserted source
Xiangchun Li

Oncogenes expand during evolution to withstand somatic amplification.

Annals of oncology : official journal of the European Society for Medical Oncology
2018-11-01 | Journal article
DOI: 10.1093/annonc/mdy397
PMID: 30204835
Source: Self-asserted source
Xiangchun Li

Translational genomics in pancreatic ductal adenocarcinoma: A review with re-analysis of TCGA dataset.

Seminars in cancer biology
2018-04-26 | Journal article
DOI: 10.1016/j.semcancer.2018.04.004
PMID: 29705685
Source: Self-asserted source
Xiangchun Li

A mutational signature associated with alcohol consumption and prognostically significantly mutated driver genes in esophageal squamous cell carcinoma.

Annals of oncology : official journal of the European Society for Medical Oncology
2018-04-01 | Journal article
DOI: 10.1093/annonc/mdy011
PMID: 29351612
PMC: PMC5913594
Source: Self-asserted source
Xiangchun Li
grade
Preferred source (of 2)‎

Genomic analysis of liver cancer unveils novel driver genes and distinct prognostic features.

Theranostics
2018-02-12 | Journal article
DOI: 10.7150/thno.22010
PMID: 29556353
PMC: PMC5858179
Source: Self-asserted source
Xiangchun Li

Characterizing genomic differences of human cancer stratified by the TP53 mutation status.

Molecular genetics and genomics : MGG
2018-01-12 | Journal article
DOI: 10.1007/s00438-018-1416-7
PMID: 29330617
Source: Self-asserted source
Xiangchun Li

Oncogenes without a Neighboring Tumor-Suppressor Gene Are More Prone to Amplification.

Molecular biology and evolution
2017-04-01 | Journal article
DOI: 10.1093/molbev/msw295
PMID: 28087780
PMC: PMC5400371
Source: Self-asserted source
Xiangchun Li

Distinct Subtypes of Gastric Cancer Defined by Molecular Characterization Include Novel Mutational Signatures with Prognostic Capability.

Cancer research
2016-02-08 | Journal article
DOI: 10.1158/0008-5472.can-15-2443
PMID: 26857262
Source: Self-asserted source
Xiangchun Li

Gut mucosal microbiome across stages of colorectal carcinogenesis.

Nature communications
2015-10-30 | Journal article
DOI: 10.1038/ncomms9727
PMID: 26515465
PMC: PMC4640069
Source: Self-asserted source
Xiangchun Li

Whole Exome Sequencing Identifies Frequent Somatic Mutations in Cell-Cell Adhesion Genes in Chinese Patients with Lung Squamous Cell Carcinoma.

Scientific reports
2015-10-27 | Journal article
DOI: 10.1038/srep14237
PMID: 26503331
PMC: PMC4621504
Source: Self-asserted source
Xiangchun Li

Comparative genomic analysis reveals bilateral breast cancers are genetically independent.

Oncotarget
2015-10-01 | Journal article
DOI: 10.18632/oncotarget.5569
PMID: 26378809
PMC: PMC4741642
Source: Self-asserted source
Xiangchun Li

Mutational landscape of gastric adenocarcinoma in Chinese: implications for prognosis and therapy.

Proceedings of the National Academy of Sciences of the United States of America
2015-01-12 | Journal article
DOI: 10.1073/pnas.1422640112
PMID: 25583476
PMC: PMC4313862
Source: Self-asserted source
Xiangchun Li

Novel recurrently mutated genes and a prognostic mutation signature in colorectal cancer.

Gut
2014-06-20 | Journal article
DOI: 10.1136/gutjnl-2013-306620
PMID: 24951259
PMC: PMC4392212
Source: Self-asserted source
Xiangchun Li

Identification of genomic alterations in oesophageal squamous cell cancer.

Nature
2014-03-16 | Journal article
DOI: 10.1038/nature13176
PMID: 24670651
Source: Self-asserted source
Xiangchun Li
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