Personal information

Activities

Employment (1)

University of Duisburg-Essen: Essen, DE

2009-10-01 to present (Medical Microbiology)
Employment
Source: Self-asserted source
Torben Knuschke

Education and qualifications (2)

University of Duisburg-Essen: Essen, DE

2009-10-01 to 2013-02-12 | Dr. rer. nat.
Education
Source: Self-asserted source
Torben Knuschke

University of Duisburg-Essen: Essen, DE

2007-10 to 2009-09 | M.Sc.
Education
Source: Self-asserted source
Torben Knuschke

Funding (1)

GRK 1949:  Immune Response in Infectious Diseases - Regulation between Innate and Adaptive Immunity

2014-01-01 to present | Grant
German Research Foundation (Bonn, DE)
GRANT_NUMBER: 231604701
Source: Self-asserted source
Torben Knuschke via DimensionsWizard

Works (26)

Influenza virus infection enhances tumour-specific CD8+ T-cell immunity, facilitating tumour control

PLOS Pathogens
2024-01-25 | Journal article
Contributors: Philine Steinbach; Peter Palese; Eva Pastille; Lara Kaumanns; Alexandra Adamczyk; Kathrin Sutter; Wiebke Hansen; Ulf Dittmer; Jan Buer; Astrid M. Westendorf et al.
Source: check_circle
Crossref

CD47 restricts antiviral function of alveolar macrophages during influenza virus infection

iScience
2022-12 | Journal article | Author
Part of ISSN: 2589-0042
Contributors: Christina Wenzek; Philine Steinbach; Florian Wirsdörfer; Kathrin Sutter; Julia D. Boehme; Robert Geffers; Robert Klopfleisch; Dunja Bruder; Verena Jendrossek; Jan Buer et al.
Source: Self-asserted source
Torben Knuschke

Immunotherapy With Interferon α11, But Not Interferon Beta, Controls Persistent Retroviral Infection

Frontiers in Immunology
2022-01-20 | Journal article
Part of ISSN: 1664-3224
Contributors: Mara Schwerdtfeger; Julia Dickow; Yasmin Schmitz; Sandra Francois; Zehra Karakoese; Anna Malyshkina; Torben Knuschke; Ulf Dittmer; Kathrin Sutter
Source: Self-asserted source
Torben Knuschke

A Combination of Anti-PD-L1 Treatment and Therapeutic Vaccination Facilitates Improved Retroviral Clearance via Reactivation of Highly Exhausted T Cells.

mBio
2021-02-02 | Journal article
Source: Self-asserted source
Torben Knuschke
grade
Preferred source (of 2)‎

In vivo biodistribution of calcium phosphate nanoparticles after intravascular, intramuscular, intratumoral, and soft tissue administration in mice investigated by small animal PET/CT

Acta Biomaterialia
2020-06 | Journal article
Part of ISSN: 1742-7061
Contributors: Sebastian Kollenda; Jasmin Klose; Torben Knuschke; Viktoriya Sokolova; Jochen Schmitz; Magdalena Staniszewska; Pedro Fragoso Costa; Ken Herrmann; Astrid M. Westendorf; Wolfgang P. Fendler et al.
Source: Self-asserted source
Torben Knuschke

Effective Activation of Human Antigen-Presenting Cells and Cytotoxic CD8<sup>+</sup> T Cells by a Calcium Phosphate-Based Nanoparticle Vaccine Delivery System

Vaccines
2020-03 | Journal article | Author
Contributors: Florian Scheffel; Torben Knuschke; Lucas Otto; Sebastian Kollenda; Viktoriya Sokolova; Christine Cosmovici; Jan Buer; Jörg Timm; Matthias Epple; Astrid M. Westendorf
Source: check_circle
Multidisciplinary Digital Publishing Institute
grade
Preferred source (of 2)‎

Combination immunotherapy with anti-PD-L1 antibody and depletion of regulatory T cells during acute viral infections results in improved virus control but lethal immunopathology

PLOS Pathogens
2020-03-30 | Journal article
Part of ISSN: 1553-7374
Contributors: Paul David; Malgorzata Drabczyk-Pluta; Eva Pastille; Torben Knuschke; Tanja Werner; Nadine Honke; Dominik Andre Megger; Ilseyar Akhmetzyanova; Namir Shaabani; Annette Eyking-Singer et al.
Source: Self-asserted source
Torben Knuschke

A Tumor-Peptide–Based Nanoparticle Vaccine Elicits Efficient Tumor Growth Control in Antitumor Immunotherapy

Molecular Cancer Therapeutics
2019-04-08 | Journal article
Part of ISSN: 1535-7163
Contributors: Carolin Heße; Sebastian Kollenda; Olga Rotan; Eva Pastille; Alexandra Adamczyk; Christina Wenzek; Wiebke Hansen; Matthias Epple; Jan Buer; Astrid M. Westendorf et al.
Source: Self-asserted source
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Session 5: Biomaterials - Inorganic

Biomedical Engineering / Biomedizinische Technik
2019-02-01 | Journal article
Part of ISSN: 1862-278X
Contributors: V. Sokolova; Z. Shi; S. Huang; Y. Du; M. Kopp; A. Frede; T. Knuschke; J. Buer; D. Yang; A. M. Westendorf et al.
Source: Self-asserted source
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A systematic electron microscopic study on the uptake of barium sulphate nano-, submicro-, microparticles by bone marrow-derived phagocytosing cells

Acta Biomaterialia
2018-10 | Journal article
Part of ISSN: 1742-7061
Contributors: V. Sokolova; K. Loza; T. Knuschke; J. Heinen-Weiler; H. Jastrow; M. Hasenberg; J. Buer; A.M. Westendorf; M. Gunzer; M. Epple
Source: Self-asserted source
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Induction of Type I Interferons by Therapeutic Nanoparticle-Based Vaccination Is Indispensable to Reinforce Cytotoxic CD8+ T Cell Responses During Chronic Retroviral Infection

Frontiers in Immunology
2018-04 | Journal article
Part of ISSN: 1664-3224
Contributors: Torben Knuschke; Olga Rotan; Wibke Bayer; Sebastian Kollenda; Julia Dickow; Kathrin Sutter; Wiebke Hansen; Ulf Dittmer; Karl S. Lang; Matthias Epple et al.
Source: Self-asserted source
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Delivery of the TLR ligand poly(I:C) to liver cells in vitro and in vivo by calcium phosphate nanoparticles leads to a pronounced immunostimulation

Acta Biomaterialia
2017 | Journal article
Part of ISSN: 1742-7061
Contributors: Viktoriya Sokolova; Zou Shi; Shunmei Huang; Yanqin Du; Mathis Kopp; Annika Frede; Torben Knuschke; Jan Buer; Dongliang Yang; Jun Wu et al.
Source: Self-asserted source
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Local delivery of siRNA-loaded calcium phosphate nanoparticles abates pulmonary inflammation

Nanomedicine: Nanotechnology, Biology and Medicine
2017-11 | Journal article
Part of ISSN: 1549-9634
Contributors: Annika Frede; Bernhard Neuhaus; Torben Knuschke; Munisch Wadwa; Sebastian Kollenda; Robert Klopfleisch; Wiebke Hansen; Jan Buer; Dunja Bruder; Matthias Epple et al.
Source: Self-asserted source
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Avidin-conjugated calcium phosphate nanoparticles as a modular targeting system for the attachment of biotinylated molecules in vitro and in vivo

Acta Biomaterialia
2017-07 | Journal article
Part of ISSN: 1742-7061
Contributors: Selina Beatrice van der Meer; Torben Knuschke; Annika Frede; Nina Schulze; Astrid M. Westendorf; Matthias Epple
Source: Self-asserted source
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Combination of nanoparticle-based therapeutic vaccination and transient ablation of regulatory T cells enhances anti-viral immunity during chronic retroviral infection

Retrovirology
2016-04 | Journal article
Part of ISSN: 1742-4690
Contributors: Torben Knuschke; Olga Rotan; Wibke Bayer; Viktoriya Sokolova; Wiebke Hansen; Tim Sparwasser; Ulf Dittmer; Matthias Epple; Jan Buer; Astrid M. Westendorf
Source: Self-asserted source
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Virus-Induced Type I Interferon Deteriorates Control of Systemic <b><i>Pseudomonas Aeruginosa</i></b> Infection

Cellular Physiology and Biochemistry
2015-07 | Journal article
Part of ISSN: 1015-8987
Contributors: Katja Merches; Vishal Khairnar; Torben Knuschke; Namir Shaabani; Nadine Honke; Vikas Duhan; Mike Recher; Alexander A. Navarini; Cornelia Hardt; Dieter Häussinger et al.
Source: Self-asserted source
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Prophylactic and therapeutic vaccination with a nanoparticle-based peptide vaccine induces efficient protective immunity during acute and chronic retroviral infection

Nanomedicine: Nanotechnology, Biology and Medicine
2014-11 | Journal article
Part of ISSN: 1549-9634
Contributors: Torben Knuschke; Wibke Bayer; Olga Rotan; Viktoriya Sokolova; Munisch Wadwa; Carsten J. Kirschning; Wiebke Hansen; Ulf Dittmer; Matthias Epple; Jan Buer et al.
Source: Self-asserted source
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The type of adjuvant strongly influences the T-cell response during nanoparticle-based immunization

Human Vaccines & Immunotherapeutics
2013-08 | Journal article
Part of ISSN: 2164-5515
Contributors: Torben Knuschke; Matthias Epple; Astrid M Westendorf
Source: Self-asserted source
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Mechanism of the uptake of cationic and anionic calcium phosphate nanoparticles by cells

Acta Biomaterialia
2013-07 | Journal article
Part of ISSN: 1742-7061
Contributors: Viktoriya Sokolova; Diana Kozlova; Torben Knuschke; Jan Buer; Astrid M. Westendorf; Matthias Epple
Source: Self-asserted source
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Immunization with Biodegradable Nanoparticles Efficiently Induces Cellular Immunity and Protects against Influenza Virus Infection

The Journal of Immunology
2013-05-10 | Journal article
Part of ISSN: 0022-1767
Contributors: Torben Knuschke; Viktoriya Sokolova; Olga Rotan; Munisch Wadwa; Matthias Tenbusch; Wiebke Hansen; Peter Staeheli; Matthias Epple; Jan Buer; Astrid M. Westendorf
Source: Self-asserted source
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Cell targeting by antibody-functionalized calcium phosphatenanoparticles

J. Mater. Chem.
2012 | Journal article
Part of ISSN: 0959-9428
Contributors: Diana Kozlova; Svitlana Chernousova; Torben Knuschke; Jan Buer; Astrid M. Westendorf; Matthias Epple
Source: Self-asserted source
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Calcium phosphate nanoparticles as versatile carrier for small and large molecules across cell membranes

Journal of Nanoparticle Research
2012-06-04 | Journal article
Part of ISSN: 1388-0764
Contributors: Viktoriya Sokolova; Olga Rotan; Jan Klesing; Perihan Nalbant; Jan Buer; Torben Knuschke; Astrid M. Westendorf; Matthias Epple
Source: Self-asserted source
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Quantitative determination of the composition of multi-shell calcium phosphate–oligonucleotide nanoparticles and their application for the activation of dendritic cells

Acta Biomaterialia
2011-11 | Journal article
Part of ISSN: 1742-7061
Contributors: V. Sokolova; T. Knuschke; J. Buer; A.M. Westendorf; M. Epple
Source: Self-asserted source
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CD8+ T-Cell Response Promotes Evolution of Hepatitis C Virus Nonstructural Proteins

Gastroenterology
2011-06 | Journal article
Part of ISSN: 0016-5085
Contributors: Marianne Ruhl; Torben Knuschke; Kevin Schewior; Lejla Glavinic; Christoph Neumann-Haefelin; Dae-In Chang; Marina Klein; Falko M. Heinemann; Hannelore Tenckhoff; Manfred Wiese et al.
Source: Self-asserted source
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Generation and function of immunosuppressive human and murine CD8+ T cells by transforming growth factor-β and retinoic acid

Immunology
2011-06 | Journal article
Part of ISSN: 0019-2805
Contributors: Diana Fleissner; Annika Frede; Markus Knott; Torben Knuschke; Robert Geffers; Wiebke Hansen; Gustav Dobos; Jost Langhorst; Jan Buer; Astrid M. Westendorf
Source: Self-asserted source
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CD8+ T cell selection pressure is a major driving force for evolution of hepatitis C virus nonstructural proteins

Zeitschrift für Gastroenterologie
2011-01 | Journal article
Part of ISSN: 0044-2771
Contributors: M Ruhl; T Knuschke; K Schewior; M Wiese; H Tenckhoff; U Spengler; J Nattermann; D Hoffmann; J Timm
Source: Self-asserted source
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Peer review (6 reviews for 4 publications/grants)

Review activity for ACS applied materials & interfaces. (1)
Review activity for ACS nano. (2)
Review activity for Cancer immunology and immunotherapy. (2)
Review activity for Naunyn-Schmiedeberg's archives of pharmacology (1)