Personal information

Activities

Employment (3)

UCSF Medical Center: San Francisco, CA, US

2020-09-14 to present | Assistant Professor (Cardiology)
Employment
Source: Self-asserted source
Connor O'Brien

Stanford University: Stanford, California, US

2019-07-01 to 2020-06-30 | Fellow (Allergy, Critical Care, and Pulmonary Medicine)
Employment
Source: Self-asserted source
Connor O'Brien

Stanford University: Palo Alto, CA, US

2018-07-01 to 2019-06-30 | Post-doctoral Fellow (Cardiovascular Medicine)
Employment
Source: Self-asserted source
Connor O'Brien

Education and qualifications (4)

Stanford Hospital and Clinics: Stanford, CA, US

2015 to 2018 | Fellowship (Cardiovascular Medicine)
Education
Source: Self-asserted source
Connor O'Brien

Stanford Hospital and Clinics: Stanford, CA, US

2012 to 2015 | Internship and Residency (Internal Medicine )
Education
Source: Self-asserted source
Connor O'Brien

Columbia University College of Physicians and Surgeons: New York, NY, US

2007 to 2012 | MD
Education
Source: Self-asserted source
Connor O'Brien

University of Pennsylvania: Philadelphia, PA, US

2001 to 2005 | BA (Double major, Biology and Biological Basis of Behavior)
Education
Source: Self-asserted source
Connor O'Brien

Professional activities (2)

American College of Cardiology: Washington, DC, US

2020-10 to present | Fellow
Invited position
Source: Self-asserted source
Connor O'Brien

Society of Critical Care Medicine: Mount Prospect, IL, US

2020-02 to present | Ultrasound Course Faculty
Service
Source: Self-asserted source
Connor O'Brien

Funding (1)

Using Exosomes to Preserve Viability and Function in Anthracycline Induced Cardiomyopathy Patient Specific Cardiomyocytes After Exposure to Doxorubicin

2017-08-01 to 2019-07-31 | Grant
National Heart Lung and Blood Institute (Bethesda, US)
GRANT_NUMBER: F32HL139046
Source: Self-asserted source
Connor O'Brien via DimensionsWizard

Works (43)

Dual Mechanism of Action: Exosomes from Human iPSC-Cardiomyocytes and Mesenchymal Stem Cells Restore Injured Myocardium

2024-05-30 | Preprint
Contributors: Eileen Tzng; Nathan Bayardo; Gentaro Ikeda; Hiroyuki Takashima; Jennifer Lyons; Mihoko Bennett; Connor G O’Brien; Phillip C. Yang
Source: check_circle
Crossref

Association between Obesity and Length of COVID-19 Hospitalization: Unexpected Insights from the American Heart Association National COVID-19 Registry

Journal of Obesity & Metabolic Syndrome
2022 | Journal article
Contributors: Collins, William J.; Chang, Andrew Y.; Weng, Yingjie; Dahlen, Alex; O'Brien, Connor G.; Hom, Jason; Ahuja, Neera; Rodriguez, Fatima; Rohatgi, Nidhi
Source: check_circle
Web of Science Researcher Profile Sync

Critical Care Cardiology Trials Network (CCCTN): a cohort profile

European Heart Journal - Quality of Care and Clinical Outcomes
2022 | Journal article
Contributors: Metkus, Thomas S.; Baird-Zars, Vivian M.; Alfonso, Carlos E.; Alviar, Carlos L.; Barnett, Christopher F.; Barsness, Gregory W.; Berg, David D.; Bertic, Mia; Bohula, Erin A.; Burke, James et al.
Source: check_circle
Web of Science Researcher Profile Sync

Impact of Bradyarrhythmias Requiring Pacing on Outcomes in Patients With COVID-19

JACC: Clinical Electrophysiology
2022 | Journal article
Contributors: Vasti, Elena C.; Ashland, Melanie D.; O'Donnell, Christian; Rodriguez, Fatima; Wang, Paul; O'Brien, Connor G.
Source: check_circle
Web of Science Researcher Profile Sync

Manganese-Enhanced MRI (MEMRI) Determines the Mechanistic Efficacy of Exosome Therapy in a Porcine Myocardial Infarction Model

Circulation
2022 | Journal article
Contributors: Takashima, Hiroyuki; Ikeda, Gentaro; Zhao, Chunli; Bayardo, Nathan; O'Brien, Connor; Yang, Phillip C.
Source: check_circle
Web of Science Researcher Profile Sync

Mitochondria-Rich Extracellular Vesicles From Stem Cell-Derived Cardiomyocytes Restore Cardiac Energy Metabolism of Ischemic Myocardium in a Preclinical Pig Model

Circulation
2022 | Journal article
Contributors: Ikeda, Gentaro; Takashima, Hiroyuki; Zhao, Chunli; Bayardo, Nathan; Lyins, Jennifer; O'Brien, Connor; Yang, Phillip C.
Source: check_circle
Web of Science Researcher Profile Sync

The shock team: a multidisciplinary approach to early patient phenotyping and appropriate care escalation in cardiogenic shock

Current Opinion in Cardiology
2022 | Journal article
Contributors: Brusca, Samuel B.; Caughron, Hope; Njoroge, Joyce N.; Cheng, Richard; O'Brien, Connor G.; Barnett, Christopher F.
Source: check_circle
Web of Science Researcher Profile Sync

Training in Critical Care Cardiology Within Critical Care Medicine Fellowship: A Novel Pathway.

Journal of the American College of Cardiology
2022-02-01 | Journal article
Source: Self-asserted source
Connor O'Brien
grade
Preferred source (of 2)‎

Critical care management of the patient with pulmonary hypertension.

European heart journal. Acute cardiovascular care
2022-01-01 | Journal article
Source: Self-asserted source
Connor O'Brien

N-Terminal Pro-B-Type Natriuretic Peptide as a Biomarker for the Severity and Outcomes With COVID-19 in a Nationwide Hospitalized Cohort.

Journal of the American Heart Association
2021-12-10 | Journal article
WOSUID:

MEDLINE:34889112

Part of ISSN: 2047-9980
Contributors: O'Donnell, Christian; Ashland, Melanie D.; Vasti, Elena C.; Lu, Ying; Chang, Andrew Y.; Wang, Paul; Daniels, Lori B.; de Lemos, James A.; Morrow, David A.; Rodriguez, Fatima et al.
Source: check_circle
Stanford University
grade
Preferred source (of 2)‎

The Use of Factor Eight Inhibitor Bypass Activity (FEIBA) for the Treatment of Perioperative Hemorrhage in Left Ventricular Assist Device Implantation

Journal of Cardiothoracic and Vascular Anesthesia
2021-09 | Journal article
Contributors: Christian O'Donnell; Alexander J. Rodriguez; Jai Madhok; Husham Sharifi; Hanjay Wang; Connor G. O'Brien; Jack Boyd; William Hiesinger; Joe Hsu; Charles C. Hill
Source: check_circle
Crossref
grade
Preferred source (of 3)‎

Mitochondria-Rich Extracellular Vesicles Rescue Patient-Specific Cardiomyocytes From Doxorubicin Injury

JACC: CardioOncology
2021-07 | Journal article
Part of ISSN: 2666-0873
Source: Self-asserted source
Connor O'Brien
grade
Preferred source (of 2)‎

EXOSOMES FROM HUMAN INDUCED PLURIPOTENT STEM CELL-DERIVED CARDIOMYOCYTES (ICMS) AND MESENCHYMAL STEM CELLS (MSCS) RECOVER HEART FUNCTION IN PORCINE ACUTE MYOCARDIAL INFARCTION (MI) MODEL

2021-05-11 | Conference paper
WOSUID:

WOS:000647487500020

Part of ISSN: 1558-3597
Part of ISSN: 0735-1097
Contributors: Bayardo, Nathan; O'Brien, Connor; Vaskova, Evgeniya; Lyons, Jennifer; Tada, Yuko; Yang, Phillip
Source: check_circle
Stanford University
grade
Preferred source (of 2)‎

A Phase II study of autologous mesenchymal stromal cells and c-kit positive cardiac cells, alone or in combination, in patients with ischaemic heart failure: the CCTRN CONCERT-HF trial.

European journal of heart failure
2021-04-03 | Journal article
Source: Self-asserted source
Connor O'Brien
grade
Preferred source (of 3)‎

miR-106a-363 cluster in extracellular vesicles promotes endogenous myocardial repair via Notch3 pathway in ischemic heart injury.

Basic research in cardiology
2021-03-19 | Journal article
Source: Self-asserted source
Connor O'Brien
grade
Preferred source (of 3)‎

Mitochondria-Rich Extracellular Vesicles From Autologous Stem Cell-Derived Cardiomyocytes Restore Energetics of Ischemic Myocardium.

Journal of the American College of Cardiology
2021-03-01 | Journal article
Source: Self-asserted source
Connor O'Brien
grade
Preferred source (of 3)‎

Worldwide Survey of COVID-19-Associated Arrhythmias.

Circulation. Arrhythmia and electrophysiology
2021-02-07 | Journal article
Source: Self-asserted source
Connor O'Brien
grade
Preferred source (of 3)‎

Exosomes From Induced Pluripotent Stem Cell-Derived Cardiomyocytes vs Mesenchymal Stem Cells Demonstrate Differential Restoration of Myocardial Function in a Porcine Ischemia Reperfusion Injury Model

Circulation
2020 | Journal article
Contributors: OBrien, Connor G.; Vaskova, Evgeniya; Tada, Yuko; Jung, Jihye; Ikeda, Gentaro; Santoso, Michelle; Yang, Phillip C.
Source: check_circle
Web of Science Researcher Profile Sync

Mesenchymal Stem Cells Rescue Patient-Specific Cardiomyocyte Viability and Function Following Doxorubicin Injury via Microvesicle Mediated Mitochondrial Transfer to Recapitulate Human Clinical Trial Results

Circulation
2020 | Journal article
Contributors: OBrien, Connor G.; Ozen, Mehmet O.; Vaskova, Evgeniya; Jung, Jihye; Santoso, Michelle; Shi, Liye; Wahlquist, Christine A.; Jiang, Zewen; Jung, Yunshin; Ikeda, Gentaro et al.
Source: check_circle
Web of Science Researcher Profile Sync

Allogeneic Mesenchymal Cell Therapy in Anthracycline-Induced Cardiomyopathy Heart Failure Patients

JACC: CardioOncology
2020-09 | Journal article
Part of ISSN: 2666-0873
Source: Self-asserted source
Connor O'Brien
grade
Preferred source (of 4)‎

Electrical Storm in COVID-19.

JACC. Case reports
2020-05 | Journal article
Contributors: O'Brien C; Ning N; McAvoy J; Mitchell JE; Kalwani N; Wang P; Nguyen D; Reejhsinghani R; Rogers A; Lorenzo J
Source: Self-asserted source
Connor O'Brien via Europe PubMed Central
grade
Preferred source (of 2)‎

COVID-19 and Disruptive Modifications to Cardiac Critical Care Delivery: JACC Review Topic of the Week.

Journal of the American College of Cardiology
2020-04 | Journal article
Contributors: Katz JN; Sinha SS; Alviar CL; Dudzinski DM; Gage A; Brusca SB; Flanagan MC; Welch T; Geller BJ; Miller PE et al.
Source: Self-asserted source
Connor O'Brien via Europe PubMed Central
grade
Preferred source (of 4)‎

MITOCHONDRIA CONTAINING EXTRACELLULAR VESICLES FROM AUTOLOGOUS INDUCED PLURIPOTENT STEM CELL DERIVED CARDIOMYOCYTES RESTORE BIOENERGETICS IN ISCHEMIC MYOCARDIUM

2020-03-24 | Conference paper
WOSUID:

WOS:000522979103444

Part of ISSN: 1558-3597
Part of ISSN: 0735-1097
Contributors: Ikeda, Gentaro; Santoso, Michelle; Tada, Yuko; Vaskova, Evgeniya; O'Brien, Connor G.; Jung, Ji Hye; Yang, Phillip C.
Source: check_circle
Stanford University
grade
Preferred source (of 2)‎

Induced Pluripotent Stem Cell Derived Cardiomyocyte Exosomes Preserve Myocardial Viability and Reduce Negative Remodeling in a Porcine Model of Ischemia Reperfusion

Circulation
2019 | Journal article
Contributors: Obrien, Connor G.; Tada, Yuko; Santoso, Michelle; Lyons, Jennifer; Jung, Jihye; Jang, Albert; Vaskova, Evgeniya; Yang, Phillip C.
Source: check_circle
Web of Science Researcher Profile Sync

Microvesicles Rescue Cardiomyocytes From Doxorubicin Injury via Mitochondrial Transfer in a Patient Specific Model of Anthracycline Induced Cardiomyopathy

Circulation
2019 | Journal article
Contributors: Obrien, Connor G.; Ozen, Mehmet O.; Vaskova, Evgenia; Santoso, Michelle; Wahlquist, Christine; Jung, Ji Hye; Ikeda, Gentaro; Shi, Liye; Demirci, Utkan; Mercola, Mark et al.
Source: check_circle
Web of Science Researcher Profile Sync

Mitochondria Containing Extracellular Vesicles From Autologous Induced Pluripotent Stem Cell (iPSC)-Derived Cardiomyocytes (iCMs) Restore Bioenergetics in Ischemic Myocardium

Circulation
2019 | Journal article
Contributors: Ikeda, Gentaro; Santoso, Michelle; Vaskova, Evgeniya; Tada, Yuko; O'Brien, Connor; Jung, Ji Hye; Yang, Phillip C.
Source: check_circle
Web of Science Researcher Profile Sync

Cardiogenic Shock: Reflections at the Crossroad Between Perfusion, Tissue Hypoxia, and Mitochondrial Function.

The Canadian journal of cardiology
2019-11 | Journal article
Contributors: O'Brien C; Beaubien-Souligny W; Amsallem M; Denault A; Haddad F
Source: Self-asserted source
Connor O'Brien via Europe PubMed Central
grade
Preferred source (of 4)‎

Meta-analysis of short- and long-term efficacy of mononuclear cell transplantation in patients with myocardial infarction.

American heart journal
2019-11 | Journal article
Contributors: Yang D; O'Brien CG; Ikeda G; Traverse JH; Taylor DA; Henry TD; Bolli R; Yang PC
Source: Self-asserted source
Connor O'Brien via Europe PubMed Central
grade
Preferred source (of 4)‎

Large-Scale Assessment of a Smartwatch to Identify Atrial Fibrillation

New England Journal of Medicine
2019-11-14 | Journal article
Source: Self-asserted source
Connor O'Brien
grade
Preferred source (of 2)‎

MICROVESICLES LARGER THAN 200NM RESCUE CARDIOMYOCYTES FROM DOXORUBICIN INJURY IN A PATIENT-SPECIFIC MODEL OF ANTHRACYCLINE INDUCED CARDIOMYOPATHY

2019-03-12 | Conference paper
WOSUID:

WOS:000460565900688

Part of ISSN: 1558-3597
Part of ISSN: 0735-1097
Contributors: O'Brien, Connor; Shi, Liye; Ozgun, Mehmet; Vaskova, Evgeniya; Santoso, Michelle; Jung, Ji Hye; Ikeda, Gentaro; Demirci, Utkan; Yang, Phillip
Source: check_circle
Stanford University
grade
Preferred source (of 2)‎

Microvesicles Rescue Cardiomyocytes From Doxorubicin Injury in a Patient Specific Model of Anthracycline Induced Cardiomyopathy

Circulation
2018 | Journal article
Contributors: O'Brien, Connor G.; Shi, Liye; Santoso, Michelle R.; Jung, Ji-Hye; Vaskova, Evgeniya; Ikeda, Gentaro; Ozen, Mehmet O.; Demirci, Utkan; Yang, Phillip C.
Source: check_circle
Web of Science Researcher Profile Sync

Routine Indwelling Urethral Catheterization in Acute Heart Failure Patients Is Associated With Increased Urinary Tract Complications Without Improved Heart Failure Outcomes

CIRCULATION JOURNAL
2018-06-01 | Journal article
WOSUID:

WOS:000433142200027

Part of ISSN: 1347-4820
Part of ISSN: 1346-9843
Contributors: Jang, Albert Youngwoo; O'Brien, Connor; Chung, Wook-Jin; Oh, Pyung Chun; Yu, Jongwook; Lee, Kyounghoon; Kang, Woong Chol; Moon, Jeonggeun
Source: check_circle
Stanford University

Alternative therapies for chronic Hepatitis B patients with partial virological response to standard entecavir monotherapy

Journal of Clinical Gastroenterology
2016 | Journal article
EID:

2-s2.0-84949579946

Contributors: Chaung, K.T.; O'Brien, C.; Ha, N.B.; Nguyen, N.H.; Trinh, H.N.; Nguyen, M.H.
Source: Self-asserted source
Connor O'Brien via Scopus - Elsevier
grade
Preferred source (of 3)‎

Stem cells

Journal of Clinical Investigation
2015 | Journal article
EID:

2-s2.0-84936791706

Contributors: Neofytou, E.; O'Brien, C.G.; Couture, L.A.; Wu, J.C.
Source: Self-asserted source
Connor O'Brien via Scopus - Elsevier
grade
Preferred source (of 3)‎

Current treatment guidelines for chronic hepatitis B and their applications

Journal of Clinical Gastroenterology
2014 | Journal article
EID:

2-s2.0-84926005505

Contributors: Uribe, L.A.; O'Brien, C.G.; Wong, R.J.; Gish, R.R.; Tsai, N.; Nguyen, M.H.
Source: Self-asserted source
Connor O'Brien via Scopus - Elsevier
grade
Preferred source (of 3)‎

Evidence for pyronaridine as a highly effective partner drug for treatment of artemisinin-resistant malaria in a rodent model

Antimicrobial Agents and Chemotherapy
2014 | Journal article
EID:

2-s2.0-84891548917

Contributors: Henrich, P.P.; O'Brien, C.; Sáenz, F.E.; Cremers, S.; Kyle, D.E.; Fidock, D.A.
Source: Self-asserted source
Connor O'Brien via Scopus - Elsevier
grade
Preferred source (of 3)‎

Rescue Therapy With Entecavir (ETV) Plustenofovir (TDF) Combination Therapy Compared to ETV Monotherapy in Chronic Hepatitis B (CHB) Patients With Partial Response to ETV 0.5 mg Daily

Gastroenterology
2014 | Journal article
Contributors: O'Brien, Connor G.; Ha, Nghiem B.; Trinh, Huy N.; Li, Jiayi; Nguyen, Huy A.; Nguyen, Mindie H.
Source: check_circle
Web of Science Researcher Profile Sync

Tuberculosis associated with transient hemolytic anemia responsive to tuberculosis chemotherapy: A case report

Brazilian Journal of Infectious Diseases
2013 | Journal article
EID:

2-s2.0-84873175203

Contributors: Safe, I.P.; O'brien, C.; Ferreira, F.R.L.; de Souza, M.L.V.D.; Ramasawmy, R.
Source: Self-asserted source
Connor O'Brien via Scopus - Elsevier
grade
Preferred source (of 2)‎

Pfatp6 molecular profile of Plasmodium falciparum isolates in the western Brazilian Amazon

Malaria Journal
2012 | Journal article
EID:

2-s2.0-84859502319

Contributors: Brasil, L.W.; Areas, A.L.; Melo, G.C.; Oliveira, C.M.; C Alecrim, M.G.; G Lacerda, M.V.; O'Brien, C.; Oelemann, W.M.; Zalis, M.G.
Source: Self-asserted source
Connor O'Brien via Scopus - Elsevier
grade
Preferred source (of 3)‎

Risk factors and characterization of plasmodium vivax-associated admissions to pediatric intensive care units in the brazilian amazon

PLoS ONE
2012 | Journal article
EID:

2-s2.0-84859867064

Contributors: Lança, E.F.C.; Magalhães, B.M.L.; Vitor-Silva, S.; Siqueira, A.M.; Benzecry, S.G.; Alexandre, M.A.A.; O'Brien, C.; Bassat, Q.; Lacerda, M.V.G.
Source: Self-asserted source
Connor O'Brien via Scopus - Elsevier
grade
Preferred source (of 3)‎

In vitro and in vivo activity of frenolicin B against Plasmodium falciparum and P berghei

Journal of Antibiotics
2011 | Journal article
EID:

2-s2.0-84255195154

Contributors: Fitzgerald, J.T.; Henrich, P.P.; O'Brien, C.; Krause, M.; Ekland, E.H.; Mattheis, C.; Sá, J.M.; Fidock, D.; Khosla, C.
Source: Self-asserted source
Connor O'Brien via Scopus - Elsevier
grade
Preferred source (of 3)‎

In vivo and in vitro antimalarial properties of azithromycin-chloroquine combinations that include the resistance reversal agent amlodipine

Antimicrobial Agents and Chemotherapy
2011 | Journal article
EID:

2-s2.0-79959227019

Contributors: Pereira, M.R.; Henrich, P.P.; Sidhu, A.B.S.; Johnson, D.; Hardink, J.; Van Deusen, J.; Lin, J.; Gore, K.; O'Brien, C.; Wele, M. et al.
Source: Self-asserted source
Connor O'Brien via Scopus - Elsevier
grade
Preferred source (of 3)‎

Recent clinical and molecular insights into emerging artemisinin resistance in Plasmodium falciparum

Current Opinion in Infectious Diseases
2011 | Journal article
EID:

2-s2.0-80054973132

Contributors: O'Brien, C.; Henrich, P.P.; Passi, N.; Fidock, D.A.
Source: Self-asserted source
Connor O'Brien via Scopus - Elsevier
grade
Preferred source (of 3)‎

Peer review (18 reviews for 8 publications/grants)

Review activity for All Life (1)
Review activity for Critical ultrasound Journal. (1)
Review activity for European heart journal. (8)
Review activity for JACC. (2)
Review activity for JACC. (3)
Review activity for Journal of cardiac failure. (1)
Review activity for Journal of the American College of Cardiology (1)
Review activity for Journal of the American Society of Echocardiography : (1)