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Employment (1)

Columbia University: New York, New York, US

Employment
Source: Self-asserted source
X Shawn Liu

Works (30)

DNA Methylation in Long-term Memory

Physiology
2025-02-05 | Journal article
Contributors: Xinyue Chen; Yueqing Peng; X. Shawn Liu
Source: check_circle
Crossref

A genetically encoded actuator boosts L-type calcium channel function in diverse physiological settings

Science Advances
2024-11 | Journal article
Contributors: Pedro J. del Rivero Morfin; Diego Scala Chavez; Srinidhi Jayaraman; Lin Yang; Stefanie M. Geisler; Audrey L. Kochiss; Petronel Tuluc; Henry M. Colecraft; Steven O. Marx; X. Shawn Liu et al.
Source: check_circle
Crossref

Chronic activation of a negative engram induces behavioral and cellular abnormalities

eLife
2024-07-11 | Journal article
Contributors: Alexandra L Jellinger; Rebecca L Suthard; Bingbing Yuan; Michelle Surets; Evan A Ruesch; Albit J Caban; Shawn Liu; Monika Shpokayte; Steve Ramirez
Source: check_circle
Crossref

Chronic activation of a negative engram induces behavioral and cellular abnormalities

eLife
2024-07-11 | Journal article
Contributors: Alexandra L Jellinger; Rebecca L Suthard; Bingbing Yuan; Michelle Surets; Evan A Ruesch; Albit J Caban; Shawn Liu; Monika Shpokayte; Steve Ramirez
Source: check_circle
Crossref

Chronic activation of a negative engram induces behavioral and cellular abnormalities

2024-07-02 | Preprint
Contributors: Alexandra L. Jellinger; Rebecca L. Suthard; Bingbing Yuan; Michelle Surets; Evan A. Ruesch; Albit J. Caban; Shawn Liu; Monika Shpokayte; Steve Ramirez
Source: check_circle
Crossref

Chronic activation of a negative engram induces behavioral and cellular abnormalities

2024-04-17 | Preprint
Contributors: Alexandra L. Jellinger; Rebecca L. Suthard; Bingbing Yuan; Michelle Surets; Evan A. Ruesch; Albit J. Caban; Shawn Liu; Monika Shpokayte; Steve Ramirez
Source: check_circle
Crossref

Chronic activation of a negative engram induces behavioral and cellular abnormalities

2023-11-17 | Preprint
Contributors: Alexandra L. Jellinger; Rebecca L. Suthard; Bingbing Yuan; Michelle Surets; Evan A. Ruesch; Albit J. Caban; Shawn Liu; Monika Shpokayte; Steve Ramirez
Source: check_circle
Crossref

Multiplex epigenome editing of MECP2 to rescue Rett syndrome neurons

Science Translational Medicine
2023-01-18 | Journal article
Contributors: Junming Qian; Xiaonan Guan; Bing Xie; Chuanyun Xu; Jacqueline Niu; Xin Tang; Charles H. Li; Henry M. Colecraft; Rudolf Jaenisch; X. Shawn Liu
Source: check_circle
Crossref

Hippocampal cells segregate positive and negative engrams

Communications Biology
2022-09-26 | Journal article
Contributors: Monika Shpokayte; Olivia McKissick; Xiaonan Guan; Bingbing Yuan; Bahar Rahsepar; Fernando R. Fernandez; Evan Ruesch; Stephanie L. Grella; John A. White; X. Shawn Liu et al.
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Crossref

Fragile X Syndrome Patient-Derived Neurons Developing in the Mouse Brain Show FMR1-Dependent Phenotypes.

Biological psychiatry
2022-08-28 | Journal article
Contributors: Marine Anais Krzisch; Wu H; Yuan B; Troy Whitfield; Liu XS; Fu D; Garrett-Engele CM; Khalil AS; Lungjangwa T; Shih J et al.
Source: Self-asserted source
X Shawn Liu

MeCP2 links heterochromatin condensates and neurodevelopmental disease.

Nature
2020-07-22 | Journal article
Contributors: Charles Han Li; Eliot Coffey; Dall'Agnese A; Hannett NM; Tang X; Jonathan Henninger; Platt JM; Oksuz O; Zamudio AV; Afeyan LK et al.
Source: Self-asserted source
X Shawn Liu

Editing the Epigenome to Tackle Brain Disorders.

Trends in neurosciences
2019-11-07 | Journal article
Contributors: Liu XS; Jaenisch R
Source: Self-asserted source
X Shawn Liu

Pharmacological enhancement of KCC2 gene expression exerts therapeutic effects on human Rett syndrome neurons and Mecp2 mutant mice.

Science translational medicine
2019-07-01 | Journal article
Contributors: Xin Tang; Drotar J; Keji Li; Cullen Clairmont; Brumm AS; Austin Sullins; Wu H; Liu XS; Wang J; Gray NS et al.
Source: Self-asserted source
X Shawn Liu

Rescue of Fragile X Syndrome Neurons by DNA Methylation Editing of the FMR1 Gene.

Cell
2018-02-15 | Journal article
Contributors: Liu XS; Wu H; Marine Anais Krzisch; Wu X; Graef J; Julien Muffat; Denes Hnisz; Li CH; Yuan B; Xu C et al.
Source: Self-asserted source
X Shawn Liu

Editing DNA Methylation in the Mammalian Genome.

Cell
2016-09-01 | Journal article
Contributors: Liu XS; Wu H; xiong ji; Stelzer Y; Wu X; Czauderna S; Shu J; Dadon D; 0000-0001-8855-8647; Jaenisch R
Source: Self-asserted source
X Shawn Liu

Stromal response to Hedgehog signaling restrains pancreatic cancer progression.

Proceedings of the National Academy of Sciences of the United States of America
2014-07-14 | Journal article
Contributors: Lee JJ; Perera RM; Wang H; Wu DC; Liu XS; Han S; Fitamant J; Jones PD; Krishna Ghanta; Kawano S et al.
Source: Self-asserted source
X Shawn Liu

Plk1 phosphorylation of orc2 and hbo1 contributes to gemcitabine resistance in pancreatic cancer.

Molecular cancer therapeutics
2012-11-27 | Journal article
Contributors: Song B; Liu XS; Rice SJ; Shihuan Kuang; Elzey BD; Konieczny SF; Ratliff TL; Tony Hazbun; Chiorean EG; Liu X
Source: Self-asserted source
X Shawn Liu

Plk1 phosphorylates Sgt1 at the kinetochores to promote timely kinetochore-microtubule attachment.

Molecular and cellular biology
2012-08-06 | Journal article
Contributors: Liu XS; Song B; Tang J; Liu W; Shihuan Kuang; Liu X
Source: Self-asserted source
X Shawn Liu

Hypoxia promotes satellite cell self-renewal and enhances the efficiency of myoblast transplantation.

Development (Cambridge, England)
2012-07-04 | Journal article
Contributors: Liu W; Yefei Wen; PENGPENG BI; Lai X; Liu XS; Liu X; Shihuan Kuang
Source: Self-asserted source
X Shawn Liu

Chemical visualization of phosphoproteomes on membrane.

Molecular & cellular proteomics : MCP
2012-05-16 | Journal article
Contributors: Anton Iliuk; Liu XS; Liang Xue; Liu X; Tao WA
Source: Self-asserted source
X Shawn Liu

Polo-like kinase 1 (Plk1): an Unexpected Player in DNA Replication.

Cell division
2012-02-06 | Journal article
Contributors: Song B; Liu XS; Liu X
Source: Self-asserted source
X Shawn Liu

Plk1 phosphorylation of Orc2 promotes DNA replication under conditions of stress.

Molecular and cellular biology
2011-09-26 | Journal article
Contributors: Song B; Liu XS; Davis K; Liu X
Source: Self-asserted source
X Shawn Liu

Polo-like kinase 1 facilitates loss of Pten tumor suppressor-induced prostate cancer formation.

The Journal of biological chemistry
2011-09-02 | Journal article
Contributors: Liu XS; Song B; Elzey BD; Ratliff TL; Konieczny SF; Cheng L; Ahmad N; Liu X
Source: Self-asserted source
X Shawn Liu

Inhibition of Polo-like kinase 1 reduces beta-amyloid-induced neuronal cell death in Alzheimer's disease.

Aging
2011-09-01 | Journal article
Contributors: Song B; Davis K; Liu XS; Lee HG; Smith M; Liu X
Source: Self-asserted source
X Shawn Liu

Targeting Plk1 in cutaneous T-cell lymphomas (CTCLs).

Cell cycle (Georgetown, Tex.)
2011-05-15 | Journal article
Contributors: Liu XS; Liu X
Source: Self-asserted source
X Shawn Liu

The substrates of Plk1, beyond the functions in mitosis.

Protein & cell
2010-11-01 | Journal article
Contributors: Liu XS; Song B; Liu X
Source: Self-asserted source
X Shawn Liu

Polo-like kinase 1 phosphorylation of p150Glued facilitates nuclear envelope breakdown during prophase.

Proceedings of the National Academy of Sciences of the United States of America
2010-08-02 | Journal article
Contributors: Li H; Liu XS; Yang X; Song B; Wang Y; Liu X
Source: Self-asserted source
X Shawn Liu

Phosphorylation of CLIP-170 by Plk1 and CK2 promotes timely formation of kinetochore-microtubule attachments.

The EMBO journal
2010-07-27 | Journal article
Contributors: Li H; Liu XS; Yang X; Wang Y; Wang Y; Turner JR; Liu X
Source: Self-asserted source
X Shawn Liu

Polo-like kinase 1 phosphorylation of G2 and S-phase-expressed 1 protein is essential for p53 inactivation during G2 checkpoint recovery.

EMBO reports
2010-06-25 | Journal article
Contributors: Liu XS; Li H; Song B; Liu X
Source: Self-asserted source
X Shawn Liu

Cdc2-mediated phosphorylation of CLIP-170 is essential for its inhibition of centrosome reduplication.

The Journal of biological chemistry
2009-08-17 | Journal article
Contributors: Yang X; Li H; Liu XS; Deng A; Liu X
Source: Self-asserted source
X Shawn Liu

Peer review (10 reviews for 9 publications/grants)

Review activity for Biological psychiatry. (1)
Review activity for Cell discovery. (1)
Review activity for EMBO molecular medicine. (1)
Review activity for Molecular psychiatry. (1)
Review activity for Nature (1)
Review activity for Nature cell biology (1)
Review activity for Nature communications (2)
Review activity for Neuron. (1)
Review activity for Science. (1)