Personal information

Emails & domains

Verified email addresses

Activities

Collapse all

Employment (4)

China National Center for Bioinformation: Beijing, CN

2023-08 to present | Director
Employment
Source: Self-asserted source
Yun-Gui Yang

Beijing Institute of Genomics, Chinese Academy of Sciences, China National Center For Bioinformation: Beijing, CN: Beijing, CN

2023-08 to present | Director
Employment
Source: Self-asserted source
Yun-Gui Yang

Beijing Institute of Genomics, Chinese Academy of Sciences, China National Center For Bioinformation: Beijing, CN

2020-12 to 2023-08 | Deputy Director
Employment
Source: Self-asserted source
Yun-Gui Yang

Beijing Institute of Genomics Chinese Academy of Sciences: Beijing, Beijing, CN

2008 to 2020 | Deputy Director of CAS Key Laboratory (CAS Key Laboratory of Genomic and Precision Medicine)
Employment
Source: Self-asserted source
Yun-Gui Yang

Education and qualifications (5)

London Research Institute Clare Hall Laboratories: South Mimms, Hertfordshire, GB

2005 to 2008 | Postdcotor with Dr Tomas Lindahl
Qualification
Source: Self-asserted source
Yun-Gui Yang

International Agency for Research on Cancer: Lyon, Rhône-Alpes, FR

2003 to 2005 | Staff Scientist with Dr Zhao-Qi Wang
Qualification
Source: Self-asserted source
Yun-Gui Yang

International Agency for Research on Cancer: Lyon, Rhône-Alpes, FR

2000 to 2003 | Postodoctor with Dr Zhao-Qi Wang
Qualification
Source: Self-asserted source
Yun-Gui Yang

Shanghai Institute of Materia Medica Chinese Academy of Sciences: Shanghai, CN

1995 to 2000 | PhD candidate (Biochemistry and Molecular Biology)
Education
Source: Self-asserted source
Yun-Gui Yang

Fudan University: Shanghai, Shanghai, CN

1991 to 1995 | Bachelor (Colledge of Life Science)
Qualification
Source: Self-asserted source
Yun-Gui Yang

Professional activities (2)

Academia Europaea: Beijing, Beijing, CN

2020-08 to present | Foreign
Membership
Source: Self-asserted source
Yun-Gui Yang

The Chinese Society of Biochemistry and Molecular Biology，CSBMB: Shanghai, CN

2018 to present | Deputy Secretary-General
Service
Source: Self-asserted source
Yun-Gui Yang

Works (44)

Advanced Sequencing Techniques to Map RNA Methylation

Israel Journal of Chemistry
2024-04 | Journal article
DOI: 10.1002/ijch.202400003
Contributors: Ge‐Ge Song; Xiu Fan; Chun‐Chun Gao; Yong‐Liang Zhao; Yun‐Gui Yang
Source: check_circle
Crossref

A spatiotemporal gene expression and cell atlases of the developing rat ovary

Cell Proliferation
2023-12 | Journal article
DOI: 10.1111/cpr.13516
Contributors: Yong Shi; Yanjie Guo; Jiayi Zhou; Guanshen Cui; Jung‐Chien Cheng; Ying Wu; Yong‐Liang Zhao; Lanlan Fang; Xiao Han; Yun‐Gui Yang et al.
Source: check_circle
Crossref

Omics Views of Mechanisms for Cell Fate Determination in Early Mammalian Development

Genomics, Proteomics & Bioinformatics
2023-10-01 | Journal article
DOI: 10.1016/j.gpb.2023.03.001
Contributors: Lin-Fang Ju; Heng-Ji Xu; Yun-Gui Yang; Ying Yang
Source: check_circle
Crossref

RNA Structural Dynamics Modulate EGFR-TKI Resistance Through Controlling YRDC Translation in NSCLC Cells

Genomics, Proteomics & Bioinformatics
2023-08 | Journal article
DOI: 10.1016/j.gpb.2022.10.006
Contributors: Boyang Shi; Ke An; Yueqin Wang; Yuhan Fei; Caixia Guo; Qiangfeng Cliff Zhang; Yun-Gui Yang; Xin Tian; Quancheng Kan
Source: check_circle
Crossref

Characteristics of N 6-Methyladenosine Modification During Sexual Reproduction of Chlamydomonas Reinhardtii

Genomics, Proteomics & Bioinformatics
2023-08-01 | Journal article
DOI: 10.1016/j.gpb.2022.04.004
Contributors: Ying Lv; Fei Han; Mengxia Liu; Ting Zhang; Guanshen Cui; Jiaojiao Wang; Ying Yang; Yun-Gui Yang; Wenqiang Yang
Source: check_circle
Crossref

NSUN2-Mediated mRNA m5C Modification Regulates the Progression of Hepatocellular Carcinoma

Genomics, Proteomics & Bioinformatics
2023-08-01 | Journal article
DOI: 10.1016/j.gpb.2022.09.007
Contributors: Dan Song; Ke An; Wenlong Zhai; Luyao Feng; Yingjie Xu; Ran Sun; Yueqin Wang; Yun-Gui Yang; Quancheng Kan; Xin Tian
Source: check_circle
Crossref

NSUN2-mediated mRNA m5C Modification Regulates the Progression of Hepatocellular Carcinoma

2022-06-09 | Preprint
DOI: 10.1101/2022.06.08.495406
Contributors: Dan Song; Ke An; Wen-Long Zhai; Lu-Yao Feng; Ying-Jie Xu; Ran Sun; Yue-Qin Wang; Yun-Gui Yang; Quan-Cheng Kan; Xin Tian
Source: check_circle
Crossref

Phase separation of Ddx3xb helicase regulates maternal-to-zygotic transition in zebrafish

Cell Research
2022-06-03 | Journal article
DOI: 10.1038/s41422-022-00655-5
Contributors: Boyang Shi; Jian Heng; Jia-Yi Zhou; Ying Yang; Wan-Ying Zhang; Magdalena J. Koziol; Yong-Liang Zhao; Pilong Li; Feng Liu; Yun-Gui Yang
Source: check_circle
Crossref

Characteristics of N6-methyladenosine modification during sexual reproduction of Chlamydomonas reinhardtii

2022-03-27 | Preprint
DOI: 10.1101/2022.03.26.485907
Contributors: Ying Lv; Fei Han; Mengxia Liu; Ting Zhang; Guanshen Cui; Jiaojiao Wang; Ying Yang; Yun-Gui Yang; Wenqiang Yang
Source: check_circle
Crossref

Dynamic transcriptomic m5C and its regulatory role in RNA processing

WIREs RNA
2021-07 | Journal article
DOI: 10.1002/wrna.1639
Contributors: Yu‐Sheng Chen; Wen‐Lan Yang; Yong‐Liang Zhao; Yun‐Gui Yang
Source: check_circle
Crossref

Differential transcriptomic landscapes of multiple organs from SARS-CoV-2 early infected rhesus macaques

2021-04-16 | Preprint
DOI: 10.21203/rs.3.rs-403788/v1
Contributors: Yun-Gui Yang; Chun-Chun Gao; Man Li; Wei Deng; Yusheng Chen; Yong-Qiao Sun; Wen-Jie Li; Bing Zhang; Yongliang Zhao; Lihong Sun et al.
Source: check_circle
Crossref

METTL3 counteracts premature aging via m6A-dependent stabilization of MIS12 mRNA

Nucleic Acids Research
2020-11-04 | Journal article
DOI: 10.1093/nar/gkaa816
Contributors: Zeming Wu; Yue Shi; Mingming Lu; Moshi Song; Zihui Yu; Jilu Wang; Si Wang; Jie Ren; Yun-Gui Yang; Guang-Hui Liu et al.
Source: check_circle
Crossref

5-Methylcytosine Analysis by RNA-BisSeq

Epitranscriptomics
2019 | Book chapter
DOI: 10.1007/978-1-4939-8808-2_18
Part of ISBN: 9781493988075
Part of ISBN: 9781493988082
Part of ISSN: 1064-3745
Part of ISSN: 1940-6029
Source: Self-asserted source
Yun-Gui Yang

An alternative CTCF isoform antagonizes canonical CTCF occupancy and changes chromatin architecture to promote apoptosis

Nature Communications
2019-12 | Journal article
DOI: 10.1038/s41467-019-08949-w
Part of ISSN: 2041-1723
Source: Self-asserted source
Yun-Gui Yang

m6A modification suppresses ocular melanoma through modulating HINT2 mRNA translation

Molecular Cancer
2019-12 | Journal article
DOI: 10.1186/s12943-019-1088-x
Contributors: Ruobing Jia; Peiwei Chai; Shanzheng Wang; Baofa Sun; Yangfan Xu; Ying Yang; Shengfang Ge; Renbing Jia; Yun-Gui Yang; Xianqun Fan
Source: check_circle
Crossref

Dynamic methylome of internal mRNA N7-methylguanosine and its regulatory role in translation

Cell Research
2019-09-13 | Journal article
DOI: 10.1038/s41422-019-0230-z
Part of ISSN: 1001-0602
Part of ISSN: 1748-7838
Source: Self-asserted source
Yun-Gui Yang
grade
Preferred source (of 2)‎

RNA 5-Methylcytosine Facilitates the Maternal-to-Zygotic Transition by Preventing Maternal mRNA Decay

Molecular Cell
2019-08 | Journal article
DOI: 10.1016/j.molcel.2019.06.033
Part of ISSN: 1097-2765
Source: Self-asserted source
Yun-Gui Yang

5-methylcytosine promotes pathogenesis of bladder cancer through stabilizing mRNAs

Nature Cell Biology
2019-07-29 | Journal article
DOI: 10.1038/s41556-019-0361-y
Part of ISSN: 1465-7392
Part of ISSN: 1476-4679
Source: Self-asserted source
Yun-Gui Yang

m6A Regulates Neurogenesis and Neuronal Development by Modulating Histone Methyltransferase Ezh2

Genomics, Proteomics & Bioinformatics
2019-05 | Journal article
DOI: 10.1016/j.gpb.2018.12.007
Part of ISSN: 1672-0229
Source: Self-asserted source
Yun-Gui Yang

Identification of entacapone as a chemical inhibitor of FTO mediating metabolic regulation through FOXO1

Science Translational Medicine
2019-04-17 | Journal article
DOI: 10.1126/scitranslmed.aau7116
ISSN: 1946-6234
ISSN: 1946-6242
Source: Self-asserted source
Yun-Gui Yang

Insight into novel RNA-binding activities via large-scale analysis of lncRNA-bound proteome and IDH1-bound transcriptome

Nucleic Acids Research
2019-03-18 | Journal article
DOI: 10.1093/nar/gkz032
Part of ISSN: 0305-1048
Part of ISSN: 1362-4962
Source: Self-asserted source
Yun-Gui Yang

Idarubicin Stimulates Cell Cycle- and TET2-Dependent Oxidation of DNA 5-Methylcytosine in Cancer Cells

Chemical Research in Toxicology
2019-03-11 | Journal article
DOI: 10.1021/acs.chemrestox.9b00012
Part of ISSN: 0893-228X
Part of ISSN: 1520-5010
Source: Self-asserted source
Yun-Gui Yang

A novel m6A reader Prrc2a controls oligodendroglial specification and myelination

Cell Research
2019-01 | Journal article
DOI: 10.1038/s41422-018-0113-8
ISSN: 1001-0602
ISSN: 1748-7838
Source: Self-asserted source
Yun-Gui Yang

METTL3-mediated N6-methyladenosine mRNA modification enhances long-term memory consolidation

Cell Research
2018-11 | Journal article
DOI: 10.1038/s41422-018-0092-9
Part of ISSN: 1001-0602
Part of ISSN: 1748-7838
Source: Self-asserted source
Yun-Gui Yang

5-Hydroxymethylome in Circulating Cell-free DNA as A Potential Biomarker for Non-small-cell Lung Cancer

Genomics, Proteomics & Bioinformatics
2018-06 | Journal article
DOI: 10.1016/j.gpb.2018.06.002
Part of ISSN: 1672-0229
Source: Self-asserted source
Yun-Gui Yang

Dynamic transcriptomic m6A decoration: writers, erasers, readers and functions in RNA metabolism

Cell Research
2018-06 | Journal article
DOI: 10.1038/s41422-018-0040-8
Part of ISSN: 1001-0602
Part of ISSN: 1748-7838
Source: Self-asserted source
Yun-Gui Yang

METTL3-mediated m6A modification is required for cerebellar development

PLOS Biology
2018-06-07 | Journal article
DOI: 10.1371/journal.pbio.2004880
Part of ISSN: 1545-7885
Source: Self-asserted source
Yun-Gui Yang

Circulating tumor DNA 5-hydroxymethylcytosine as a novel diagnostic biomarker for esophageal cancer

Cell Research
2018-05 | Journal article
DOI: 10.1038/s41422-018-0014-x
Part of ISSN: 1001-0602
Part of ISSN: 1748-7838
Source: Self-asserted source
Yun-Gui Yang

Endothelial-specific m6A modulates mouse hematopoietic stem and progenitor cell development via Notch signaling

Cell Research
2018-02 | Journal article
DOI: 10.1038/cr.2017.143
Part of ISSN: 1001-0602
Part of ISSN: 1748-7838
Source: Self-asserted source
Yun-Gui Yang

m6A modulates haematopoietic stem and progenitor cell specification

Nature
2017-09 | Journal article
DOI: 10.1038/nature23883
Part of ISSN: 0028-0836
Part of ISSN: 1476-4687
Source: Self-asserted source
Yun-Gui Yang

Mettl3-mediated m6A regulates spermatogonial differentiation and meiosis initiation

Cell Research
2017-09 | Journal article
DOI: 10.1038/cr.2017.100
Part of ISSN: 1001-0602
Part of ISSN: 1748-7838
Source: Self-asserted source
Yun-Gui Yang

5-methylcytosine promotes mRNA export — NSUN2 as the methyltransferase and ALYREF as an m5C reader

Cell Research
2017-05 | Journal article
DOI: 10.1038/cr.2017.55
Part of ISSN: 1001-0602
Part of ISSN: 1748-7838
Source: Self-asserted source
Yun-Gui Yang

Cytoplasmic m6A reader YTHDF3 promotes mRNA translation

Cell Research
2017-03 | Journal article
DOI: 10.1038/cr.2017.10
Part of ISSN: 1001-0602
Part of ISSN: 1748-7838
Source: Self-asserted source
Yun-Gui Yang

ATPase activity tightly regulates RecA nucleofilaments to promote homologous recombination

Cell Discovery
2017-01-17 | Journal article
DOI: 10.1038/celldisc.2016.53
Contributors: Bailin Zhao; Dapeng Zhang; Chengmin Li; Zheng Yuan; Fangzhi Yu; Shangwei Zhong; Guibin Jiang; Yun-Gui Yang; X Chris Le; Michael Weinfeld et al.
Source: check_circle
Crossref

Nuclear m 6 A Reader YTHDC1 Regulates mRNA Splicing

Molecular Cell
2016-02 | Journal article
DOI: 10.1016/j.molcel.2016.01.012
Part of ISSN: 1097-2765
Source: Self-asserted source
Yun-Gui Yang

m6A RNA Methylation Is Regulated by MicroRNAs and Promotes Reprogramming to Pluripotency

Cell Stem Cell
2015-03 | Journal article
DOI: 10.1016/j.stem.2015.01.016
Part of ISSN: 1934-5909
Source: Self-asserted source
Yun-Gui Yang

FTO-dependent demethylation of N6-methyladenosine regulates mRNA splicing and is required for adipogenesis

Cell Research
2014-12 | Journal article
DOI: 10.1038/cr.2014.151
Part of ISSN: 1001-0602
Part of ISSN: 1748-7838
Source: Self-asserted source
Yun-Gui Yang
grade
Preferred source (of 2)‎

FTO and Obesity: Mechanisms of Association

Current Diabetes Reports
2014-05 | Journal article
DOI: 10.1007/s11892-014-0486-0
Part of ISSN: 1534-4827
Part of ISSN: 1539-0829
Source: Self-asserted source
Yun-Gui Yang

Mammalian WTAP is a regulatory subunit of the RNA N6-methyladenosine methyltransferase

Cell Research
2014-02 | Journal article
DOI: 10.1038/cr.2014.3
Part of ISSN: 1001-0602
Part of ISSN: 1748-7838
Source: Self-asserted source
Yun-Gui Yang

Redox-active quinones induces genome-wide DNA methylation changes by an iron-mediated and Tet-dependent mechanism

Nucleic Acids Research
2014-02 | Journal article
DOI: 10.1093/nar/gkt1090
Part of ISSN: 1362-4962
Part of ISSN: 0305-1048
Source: Self-asserted source
Yun-Gui Yang

Sprouts of RNA epigenetics

RNA Biology
2013-06 | Journal article
DOI: 10.4161/rna.24711
Part of ISSN: 1547-6286
Part of ISSN: 1555-8584
Source: Self-asserted source
Yun-Gui Yang

N6-methyl-adenosine (m6A) in RNA: An Old Modification with A Novel Epigenetic Function

Genomics, Proteomics & Bioinformatics
2013-02 | Journal article
DOI: 10.1016/j.gpb.2012.12.002
Part of ISSN: 1672-0229
Source: Self-asserted source
Yun-Gui Yang

ALKBH5 Is a Mammalian RNA Demethylase that Impacts RNA Metabolism and Mouse Fertility

Molecular Cell
2013-01 | Journal article
DOI: 10.1016/j.molcel.2012.10.015
Part of ISSN: 1097-2765
Source: Self-asserted source
Yun-Gui Yang

N6-Methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO

Nature Chemical Biology
2011-12 | Journal article
DOI: 10.1038/nchembio.687
Part of ISSN: 1552-4450
Part of ISSN: 1552-4469
Source: Self-asserted source
Yun-Gui Yang
How many people are using ORCID?