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Enhancing prediction of short linear protein motifs with Wregex 3.0

Computational and Structural Biotechnology Journal
2024-12 | Journal article
DOI: 10.1016/j.csbj.2024.07.013
Contributors: Gorka Prieto; Jose A. Rodríguez; Asier Fullaondo
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Crossref

Mutations of Key Functional Residues in CRM1/XPO1 Differently Alter Its Intranuclear Localization and the Nuclear Export of Endogenous Cargos

Biomolecules
2024-12-10 | Journal article
DOI: 10.3390/biom14121578
Contributors: Miren Josu Omaetxebarria; Maria Sendino; Liher Arrizabalaga; Irune Mota; Ana Maria Zubiaga; José Antonio Rodríguez
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Crossref
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High Throughput Fluorescence-Based In Vitro Experimental Platform for the Identification of Effective Therapies to Overcome Tumour Microenvironment-Mediated Drug Resistance in AML

Cancers
2023-03-27 | Journal article
DOI: 10.3390/cancers15071988
Contributors: Yoana Arroyo-Berdugo; Maria Sendino; David Greaves; Natalia Nojszewska; Orest Idilli; Chi Wai So; Lucy Di Silvio; Ruby Quartey-Papafio; Farzin Farzaneh; Jose Antonio Rodriguez et al.
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Crossref
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MARK4ren interakzioak USP21 deubikuitinasaren kokapen azpizelular dinamikoa erregulatzen du

EKAIA Euskal Herriko Unibertsitateko Zientzia eta Teknologia Aldizkaria
2021-11-18 | Journal article
DOI: 10.1387/ekaia.22644
Contributors: Iraia García-Santisteban; Anne Olazabal-Herrero; Jose Antonio Rodríguez
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Crossref

The dystrophia myotonica WD repeat‐containing protein DMWD and WDR20 differentially regulate USP12 deubiquitinase

The FEBS Journal
2021-10 | Journal article
DOI: 10.1111/febs.15875
Contributors: Anne Olazabal‐Herrero; Martin Bilbao‐Arribas; Onintza Carlevaris; Maria Sendino; Endika Varela‐Martinez; Begoña M. Jugo; Edurne Berra; Jose Antonio Rodriguez
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Crossref

Molecular Mechanisms Regulating the DNA Repair Protein APE1: A Focus on Its Flexible N-Terminal Tail Domain

International Journal of Molecular Sciences
2021-06-11 | Journal article
DOI: 10.3390/ijms22126308
Contributors: David J. López; José A. Rodríguez; Sonia Bañuelos
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RNAren N6-metiladenosina (m6A) modifikazioren rol berriak hesteko inflamazioaren garapenean eta tratamenduan

2021-06-08 | Conference paper
DOI: 10.26876/ikergazte.iv.04.19
Contributors: Ane Olazagoitia Garmendia; Maialen Sebastian de la Cruz; Iraia García Santisteban; Luis Manuel Mendoza Gomez; Alain Huerta Madrigal; Iñaki Xarles Irastorza Terradillos; Jose Antonio Rodriguez Perez; Jose Ramon Bilbao Catala; Ainara Castellanos Rubio
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Crossref

Konpartimentu-espezifikoko gertuko biotinilazioa: XPO1en esportazio-kargoak identifikatzeko hurbilketa berria

EKAIA Euskal Herriko Unibertsitateko Zientzia eta Teknologia Aldizkaria
2021-06-03 | Journal article
DOI: 10.1387/ekaia.22591
Contributors: Maria Sendino; Juanma Ramírez; Ugo Mayor; Gorka Prieto; Miren Josu Omaetxebarria; Jose Antonio Rodríguez
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Crossref

A Proteomic Approach for Systematic Mapping of Substrates of Human Deubiquitinating Enzymes

International Journal of Molecular Sciences
2021-05 | Journal article | Author
DOI: 10.3390/ijms22094851
Contributors: Juanma Ramirez; Gorka Prieto; Anne Olazabal-Herrero; Eva Borràs; Elvira Fernandez-Vigo; Unai Alduntzin; Nerea Osinalde; Javier Beaskoetxea; Benoît Lectez; Kerman Aloria et al.
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Multidisciplinary Digital Publishing Institute

The “STK38-XPO1 axis”: its general relevance and mechanistic underpinnings remain to be further characterized

Cellular and Molecular Life Sciences
2021-05-09 | Journal article
DOI: 10.1007/s00018-021-03778-x
Contributors: Jose Antonio Rodriguez
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Crossref

LUZP1 Controls Cell Division, Migration and Invasion Through Regulation of the Actin Cytoskeleton.

Frontiers in cell and developmental biology
2021-04-01 | Journal article
DOI: 10.3389/fcell.2021.624089
PMID: 33869174
Source: Self-asserted source
Jose Antonio Rodriguez

The multifunctional role of SPANX-A/D protein subfamily in the promotion of pro-tumoural processes in human melanoma.

Scientific reports
2021-02-11 | Journal article
DOI: 10.1038/s41598-021-83169-1
PMID: 33574425
PMC: PMC7878863
Source: Self-asserted source
Jose Antonio Rodriguez

Gluten-induced RNA methylation changes regulate intestinal inflammation via allele-specific <i>XPO1</i> translation in epithelial cells.

Gut
2021-02-01 | Journal article
DOI: 10.1136/gutjnl-2020-322566
PMID: 33526437
Source: Self-asserted source
Jose Antonio Rodriguez

The strength of a NES motif in the nucleocapsid protein of human coronaviruses is related to genus, but not to pathogenic capacity

2020-10-06 | Preprint
DOI: 10.1101/2020.10.06.328138
Contributors: Maria Sendino; Miren Josu Omaetxebarria; Jose Antonio Rodriguez
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Crossref

Nucleophosmin, a multifunctional nucleolar organizer with a role in DNA repair.

Biochimica et biophysica acta. Proteins and proteomics
2020-08-25 | Journal article
DOI: 10.1016/j.bbapap.2020.140532
PMID: 32853771
Source: Self-asserted source
Jose Antonio Rodriguez

Using a simple cellular assay to map NES motifs in cancer-related proteins, gain insight into CRM1-mediated NES export, and search for NES-harbouring micropeptides

2020-08-04 | Other
DOI: 10.1101/2020.08.04.234948
Contributors: Maria Sendino; Miren Josu Omaetxebarria; Gorka Prieto; Jose Antonio Rodriguez
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Crossref

LUZP1, a novel regulator of primary cilia and the actin cytoskeleton, is a contributing factor in Townes-Brocks Syndrome.

eLife
2020-06-18 | Journal article
DOI: 10.7554/elife.55957
PMID: 32553112
PMC: PMC7363444
Source: Self-asserted source
Jose Antonio Rodriguez

SPANX-A/D protein subfamily plays a key role in nuclear organisation, metabolism and flagellar motility of human spermatozoa

Scientific Reports
2020-03-27 | Journal article
DOI: 10.1038/s41598-020-62389-x
Part of ISSN: 2045-2322
Source: Self-asserted source
Jose Antonio Rodriguez

Altered Nuclear Export Signal Recognition as a Driver of Oncogenesis.

Cancer discovery
2019-07 | Journal article
DOI: 10.1158/2159-8290.cd-19-0298
PMID: 31285298
Contributors: Taylor J; Sendino M; Gorelick AN; Pastore A; Chang MT; Penson AV; Gavrila EI; Stewart C; Melnik EM; Herrejon Chavez F et al.
Source: Self-asserted source
Jose Antonio Rodriguez via Europe PubMed Central

Detailed Dissection of UBE3A-Mediated DDI1 Ubiquitination.

Frontiers in physiology
2019-05 | Journal article
DOI: 10.3389/fphys.2019.00534
PMID: 31130875
PMC: PMC6509411
Contributors: Elu N; Osinalde N; Beaskoetxea J; Ramirez J; Lectez B; Aloria K; Rodriguez JA; Arizmendi JM; Mayor U
Source: Self-asserted source
Jose Antonio Rodriguez via Europe PubMed Central

WDR20 regulates shuttling of the USP12 deubiquitinase complex between the plasma membrane, cytoplasm and nucleus

European Journal of Cell Biology
2018-11-03 | Journal article
DOI: 10.1016/j.ejcb.2018.10.003
Source: Self-asserted source
Jose Antonio Rodriguez

Hitting a moving target: inhibition of the nuclear export receptor XPO1/CRM1 as a therapeutic approach in cancer

Cancer Drug Resistance
2018-09-19 | Journal article
DOI: 10.20517/cdr.2018.09
Source: Self-asserted source
Jose Antonio Rodriguez

Truncated SALL1 Impedes Primary Cilia Function in Townes-Brocks Syndrome.

American journal of human genetics
2018-02 | Journal article
DOI: 10.1016/j.ajhg.2017.12.017
PMID: 29395072
Contributors: Bozal-Basterra L; Martín-Ruíz I; Pirone L; Liang Y; Sigurðsson JO; Gonzalez-Santamarta M; Giordano I; Gabicagogeascoa E; de Luca A; Rodríguez JA et al.
Source: Self-asserted source
Jose Antonio Rodriguez via Europe PubMed Central

Conformational stabilization as a strategy to prevent nucleophosmin mislocalization in leukemia

Scientific Reports
2017 | Journal article
DOI: 10.1038/s41598-017-14497-4
OTHER-ID:

UPV/EHU:5040080
Contributors: Urbaneja,M. A.; Skjærven,L.; Aubi,O.; Underhaug,J.; López,D. J.; Arregi,I.; Alonso-Mariño,M.; Cuevas,A.; Rodríguez,J. A.; Martinez,A. et al.
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Universidad del País Vasco

Therapeutic effects of XPO1 inhibition in thymic epithelial tumors

Cancer Research
2017 | Journal article
DOI: 10.1158/0008-5472.CAN-17-1323
OTHER-ID:

UPV/EHU:5040236
Contributors: Conforti,F.; Zhang,X.; Rao,G.; De Pas,T.; Yonemori,Y.; Rodriguez,J. A.; McCutcheon,J. N.; Rahhal,R.; Alberobello,A. T.; Wang,Y. et al.
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Universidad del País Vasco

USP1 deubikitinasa pankrea-minbiziaren aurkako itu terapeutiko gisa

2017-05-07 | Conference paper
DOI: 10.26876/ikergazte.ii.04.07
Contributors: Jose Antonio Rodriguez Perez; Elisa Giovannetti; J. Peters Godefridus; Maria Sendino Mouliet; Anne Olazabal Herrero
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Crossref

A cellular reporter to evaluate CRM1 nuclear export activity: functional analysis of the cancer-related mutant E571K

Cellular and Molecular Life Sciences
2016 | Journal article
DOI: 10.1007/s00018-016-2292-0
OTHER-ID:

UPV/EHU:5039975
Contributors: García-Santisteban,I.; Arregi,I.; Alonso-Mariño,M.; Urbaneja,M. A.; Garcia-Vallejo,J. J.; Bañuelos,S.; Rodríguez,J. A.
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Universidad del País Vasco

Description of USP12 nuclear export sequence

Proceedings of the National Academy of Sciences of the United States of America
2016 | Conference paper
DOI: 10.1073/pnas.1606081113
OTHER-ID:

UPV/EHU:5039987
Contributors: Rodriguez,J. A.
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Universidad del País Vasco
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Mutations in the "Fingers" subdomain of the deubiquitinase USP1 modulate its function and activity

The FEBS journal
2016 | Journal article
DOI: 10.1111/febs.13648
OTHER-ID:

UPV/EHU:5039980
Contributors: Olazabal-Herrero,A.; García-Santisteban,I.; Rodríguez,J. A.
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Universidad del País Vasco

Proteome-wide search for functional motifs altered in tumors: Prediction of nuclear export signals inactivated by cancer-related mutations

Scientific Reports
2016 | Journal article
DOI: 10.1038/srep25869
OTHER-ID:

UPV/EHU:5039984
Contributors: Prieto,G.; Fullaondo,A.; Rodríguez,J. A.
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Universidad del País Vasco

Leukemia-associated mutations in nucleophosmin alter recognition by CRM1: molecular basis of aberrant transport

PLoS ONE
2015 | Journal article
DOI: 10.1371/journal.pone.0130610
OTHER-ID:

UPV/EHU:5039970
Contributors: Arregi,I.; Falces,J.; Olazabal-Herrero,A.; Alonso-Mariño,M.; Taneva,S. G.; Rodríguez,J. A.; Urbaneja,M. A.; Bañuelos,S.
Source: check_circle
Universidad del País Vasco

Molecular pathways: Anticancer activity by inhibition of nucleocytoplasmic shuttling

Clinical Cancer Research
2015 | Journal article
DOI: 10.1158/1078-0432.CCR-15-0408
OTHER-ID:

UPV/EHU:5039972
Contributors: Conforti,F.; Wang,Y.; Rodriguez,J. A.; Alberobello,A. T.; Zhang,Y. -W; Giaccone,G.
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Universidad del País Vasco

Structure-function analysis of USP1: insights into the role of Ser313 phosphorylation site and the effect of cancer-associated mutations on autocleavage

Molecular Cancer
2015 | Journal article
DOI: 10.1186/s12943-015-0311-7
OTHER-ID:

UPV/EHU:5039981
Contributors: Olazabal-Herrero,Anne; Garcia-Santisteban,Iraia; Antonio Rodriguez,Jose
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Universidad del País Vasco

Interplay between nuclear transport and ubiquitin/SUMO modifications in the regulation of cancer-related proteins

Seminars in Cancer Biology
2014 | Journal article
DOI: 10.1016/j.semcancer.2014.03.005
OTHER-ID:

UPV/EHU:5039988
Contributors: Rodríguez,J. A.
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Universidad del País Vasco

Prediction of nuclear export signals using weighted regular expressions (Wregex)

Bioinformatics
2014 | Journal article
DOI: 10.1093/bioinformatics/btu01
OTHER-ID:

UPV/EHU:5039983
Contributors: Prieto,G.; Fullaondo,A.; Rodriguez,J. A.
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Universidad del País Vasco

USP1 (ubiquitin specific peptidase 1)

Atlas of Genetics and Cytogenetics in Oncology and Haematology
2014 | Journal article
DOI: 10.4267/2042/53649
OTHER-ID:

UPV/EHU:5040234
Contributors: García-Santisteban,Iraia; Peters,Godefridus J.; Rodriguez,J. A.; Giovannetti,E.
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Universidad del País Vasco

E2F2 and CREB cooperatively regulate transcriptional activity of cell cycle genes

Nucleic acids research
2013 | Journal article
DOI: 10.1093/nar/gkt821
OTHER-ID:

UPV/EHU:5039979
Contributors: Laresgoiti,U.; Apraiz,A.; Olea,M.; Mitxelena,J.; Osinalde,N.; Rodriguez,J. A.; Fullaondo,A.; Zubiaga,A. M.
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Universidad del País Vasco

The nuclear protein ALY binds to and modulates the activity of transcription factor E2F2

Molecular and Cellular Proteomics
2013 | Journal article
DOI: 10.1074/mcp.M112.024158
OTHER-ID:

UPV/EHU:5039982
Contributors: Osinalde,N.; Olea,M.; Mitxelena,J.; Aloria,K.; Rodriguez,J. A.; Fullaondo,A.; Arizmendi,J. M.; Zubiaga,A. M.
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Universidad del País Vasco

USP1 deubiquitinase: Cellular functions, regulatory mechanisms and emerging potential as target in cancer therapy

Molecular Cancer
2013 | Journal article
DOI: 10.1186/1476-4598-12-91
OTHER-ID:

UPV/EHU:5039977
Contributors: García-Santisteban,I.; Peters,G. J.; Giovannetti,E.; Rodríguez,J. A.
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Universidad del País Vasco

A global survey of CRM1-dependent nuclear export sequences in the human deubiquitinase family

Biochemical Journal
2012 | Journal article
DOI: 10.1042/BJ20111300
OTHER-ID:

UPV/EHU:5039976
Contributors: García-Santisteban,I.; Bañuelos,S.; Rodríguez,J. A.
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Universidad del País Vasco

Absence of COCH gene mutations in patients with superior semicircular canal dehiscence

American Journal of Medical Genetics Part A
2012 | Journal article
DOI: 10.1002/ajmg.a.34377
OTHER-ID:

UPV/EHU:5039973
Contributors: Crovetto,Miguel A.; Whyte,Jaime; Sarasola,Esther; Rodriguez,Jose A.; Garcia-Barcina,Maria J.
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Universidad del País Vasco

Etsaia ezagutzen

Elhuyar: zientzia eta teknika
2012 | Magazine article
OTHER-ID:

https://dialnet.unirioja.es/servlet/extart?codigo=3918655

OTHER-ID:

UPV/EHU:5040237
Contributors: Rodríguez Pérez,Jose Antonio
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Universidad del País Vasco

Two nuclear localization signals in USP1 mediate nuclear import of the USP1/UAF1 complex

PLoS ONE
2012 | Journal article
DOI: 10.1371/journal.pone.0038570
OTHER-ID:

UPV/EHU:5039978
Contributors: Garcia-Santisteban,I.; Zorroza,K.; Rodriguez,J. A.
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Universidad del País Vasco

A short in-frame deletion in NTRK1 tyrosine kinase domain caused by a novel splice site mutation in a patient with congenital insensitivity to pain with anhidrosis

BMC Medical Genetics
2011 | Journal article
DOI: 10.1186/1471-2350-12-86
OTHER-ID:

UPV/EHU:5039989
Contributors: Sarasola,E.; Rodríguez,J. A.; Garrote,E.; Arístegui,J.; García-Barcina,M. J.
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Universidad del País Vasco

Laborategitik klinikara

Elhuyar: zientzia eta teknika
2011 | Magazine article
OTHER-ID:

https://dialnet.unirioja.es/servlet/extart?codigo=3793131

OTHER-ID:

UPV/EHU:5040238
Contributors: Rodríguez Pérez,Jose Antonio
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Universidad del País Vasco

Combined assessment of EGFR pathway-related molecular markers and prognosis of NSCLC patients

British Journal of Cancer
2009 | Journal article
DOI: 10.1038/sj.bjc.6604781
OTHER-ID:

UPV/EHU:5040074
Contributors: Ruiz,M. I. G.; Floor,K.; Steinberg,S. M.; Grünberg,K.; Thunnissen,F. B. J. M.; Belien,J. A. M.; Meijer,G. A.; Peters,G. J.; Smit,E. F.; Rodriguez,J. A. et al.
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Universidad del País Vasco

Comparative proteomics analysis of caspase-9-protein complexes in untreated and cytochrome c/dATP stimulated lysates of NSCLC cells

Journal of Proteomics
2009 | Journal article
DOI: 10.1016/j.jprot.2008.11.016
OTHER-ID:

UPV/EHU:5040044
Contributors: Checinska,A.; Giaccone,G.; Rodriguez,J. A.; Kruyt,F. A. E.; Jimenez,C. R.
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Universidad del País Vasco

Apoptosis pathways and new anticancer agents

Principles of Molecular Oncology: Third Edition
2008 | Book chapter
DOI: 10.1007/978-1-59745-470-4_12
OTHER-ID:

UPV/EHU:5040062
Contributors: Kruyt,F. A. E.; Rodriguez,J. A.; Giaccone,G.
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Universidad del País Vasco

Genotype analysis of the VNTR polymorphism in the SMYD3 histone methyltransferase gene: Lack of correlation with the level of histone H3 methylation in NSCLC tissues or with the risk of NSCLC

International Journal of Cancer
2008 | Journal article
DOI: 10.1002/ijc.23227
OTHER-ID:

UPV/EHU:5039971
Contributors: Barlési,F.; Giaccone,G.; Gallegos-Ruiz,M. I.; Span,S. W.; Lefesvre,P.; Kruyt,F. A. E.; Rodriguez,J. A.
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Universidad del País Vasco

Integration of gene dosage and gene expression in non-small cell lung cancer, identification of HSP90 as potential target

PLoS ONE
2008 | Journal article
DOI: 10.1371/journal.pone.0001722
OTHER-ID:

UPV/EHU:5040052
Contributors: Gallegos Ruiz,M. I.; Floor,K.; Roepman,P.; Rodriguez,J. A.; Meijer,G. A.; Mooi,W. J.; Jassem,E.; Niklinski,J.; Muley,T.; van Zandwijk,N. et al.
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Universidad del País Vasco
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Peer review (3 reviews for 3 publications/grants)

Review activity for Cellular and molecular life sciences (1)
Review activity for Cellular oncology. (1)
Review activity for Nature reviews. (1)
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