Personal information

Activities

Employment (6)

Prinses Máxima Centrum voor Kinderoncologie: Utrecht, Utrecht, NL

2021-03 to present | Bioinformatician (Research)
Employment
Source: Self-asserted source
Minoo Ashtiani

Universität Heidelberg: Heidelberg, Baden-Württemberg, DE

2020-02-01 to 2020-11-30 | Research assistant
Employment
Source: Self-asserted source
Minoo Ashtiani

Ruprecht Karls Universität Heidelberg Medizinische Fakultät Heidelberg: Heidelberg, Baden-Württemberg, DE

2019-06-01 to 2020-01-31 | Research assistant
Employment
Source: Self-asserted source
Minoo Ashtiani

Pasteur Institute of Iran: Tehran, Tehran, IR

2014-10-01 to 2018-12-31 | Research assistant (Biotechnology)
Employment
Source: Self-asserted source
Minoo Ashtiani

Pasteur Institute of Iran: Tehran, IR

2017 to 2017 | Teaching assistant (R Software and Omics Application)
Employment
Source: Self-asserted source
Minoo Ashtiani

Amirkabir University of Technology: Tehran, IR

2017 to 2017 | Teaching assistant (An Introduction to R and RStudio Software)
Employment
Source: Self-asserted source
Minoo Ashtiani

Education and qualifications (5)

Princess Máxima Center: Utrecht, NL

2022 to present | Introduction to single-cell RNA sequencing data analysis
Qualification
Source: Self-asserted source
Minoo Ashtiani

Imam Khomeini International University: Qazvin, IR

2012-11-01 to 2017-06-17 | BSc (Faculty of Science)
Education
Source: Self-asserted source
Minoo Ashtiani

Tehran Institute of Technology: Tehran, Tehran, IR

2015 to 2015 | .NETframeworkapplicationdevelopmentfundamentals
Qualification
Source: Self-asserted source
Minoo Ashtiani

Tehran Institute of Technology: Tehran, IR

2015 to 2015 | Fundamentalsofprogrammingwith.NET (Tehran Institute of Technology)
Qualification
Source: Self-asserted source
Minoo Ashtiani

Tehran Institute of Technology: Tehran, IR

2014 to 2014 | SPSSsoftwareUsage
Qualification
Source: Self-asserted source
Minoo Ashtiani

Works (15)

RUNX1::RUNX1T1 Depletion Eliminates Stemness and Induces Bidirectional Differentiation of Acute Myeloid Leukemia

2025-02-17 | Preprint
Contributors: Polina K Derevyanko; Laura E. Swart; L. Daniel Mata Casimiro; Luca van den Brink; Anita T. van Oort; Minoo Ashtiani; C. Michel Zwaan; Anja Krippner-Heidenreich; Constanze Bonifer; Raymond Schiffelers et al.
Source: check_circle
Crossref

The MLL–Menin Interaction is a Therapeutic Vulnerability in NUP98-rearranged AML

HemaSphere
2023-08 | Journal article
Part of ISSN: 2572-9241
Contributors: Milad Rasouli; Helen Blair; Selina Troester; Katarzyna Szoltysek; Rachel Cameron; Minoo Ashtiani; Anja Krippner-Heidenreich; Florian Grebien; Gerard McGeehan; C. Michel Zwaan et al.
Source: Self-asserted source
Minoo Ashtiani

P437: EFFECTIVE IMMUNOTHERAPY OF PEDIATRIC T(8;21) ACUTE MYELOID LEUKEMIA BY REPURPOSING CD3XCD19 TARGETING BISPECIFIC ANTIBODIES

HemaSphere
2023-08-08 | Journal article
Part of ISSN: 2572-9241
Contributors: Noa Wijnen; Farnaz Barneh; Thomas Meulendijks; Kim Klein; Ester Duddebach; Annelisa Cornel; Noël Dautzenberg; Minoo Ashtiani; Anja Krippner-Heidenreich; Stefan Nierkens et al.
Source: Self-asserted source
Minoo Ashtiani

P444: SINGLE CELL RNASEQ UNCOVERING THE ROLE OF A LEUKEMIC DRIVER GENE FUSION CBFΒ::MYH11 IN THE LEUKEMIC–NICHE SIGNALING

HemaSphere
2023-08-08 | Journal article
Part of ISSN: 2572-9241
Contributors: Polina Derevyanko; Alexandra V Dolgikh; Minoo Ashtiani; Anja Krippner-Heidenreich; Ryan Nelson; John Bushweller; Yury Barbitoff; Alexander V Predeus; Olaf Heidenreich
Source: Self-asserted source
Minoo Ashtiani

CD19-Targeted immunotherapies for Treatment of Pediatric t(8;21) Leukemia

Klinische Pädiatrie
2023-05 | Conference abstract
Part of ISSN: 1439-3824
Contributors: F Barneh; T Meulendijks; N Wijnen; J Koedijk; M Ashtiani; A Krippner-Heidenreich; E Dunnebach; S Nierkens; G Kaspers; O Heidenreich
Source: Self-asserted source
Minoo Ashtiani

Nanoparticle-mediated targeting of the fusion gene RUNX1/ETO in t(8;21)-positive acute myeloid leukaemia

Leukemia
2023-04 | Journal article
Part of ISSN: 0887-6924
Part of ISSN: 1476-5551
Contributors: Hasan Issa; Laura E. Swart; Milad Rasouli; Minoo Ashtiani; Sirintra Nakjang; Nidhi Jyotsana; Konstantin Schuschel; Michael Heuser; Helen Blair; Olaf Heidenreich
Source: Self-asserted source
Minoo Ashtiani

Inhibition of the Menin-MLL1 Interaction in <i>MLL</i>-Rearranged Primary Mixed-Phenotype Acute Leukemia Samples Promotes Leukemic Differentiation

Blood
2022-11-15 | Journal article
Part of ISSN: 0006-4971
Part of ISSN: 1528-0020
Contributors: Katarzyna Szoltysek; Rachel L. Cameron; Anja Krippner-Heidenreich; Milad Rasouli; Jayne Y. Hehir-Kwa; Elizabeth K. Schweighart; Minoo Ashtiani; Janine Stutterheim; Josef Vormoor; Olaf Heidenreich
Source: Self-asserted source
Minoo Ashtiani

Epigenetic regulator genes direct lineage switching in <i>MLL/AF4</i> leukaemia

Blood
2022-07-15 | Journal article
Part of ISSN: 0006-4971
Part of ISSN: 1528-0020
Contributors: Minoo Ashtiani
Source: Self-asserted source
Minoo Ashtiani

P465: A LIPID NANOPARTICLE DELIVERY SYSTEM FOR TARGETING THE LEUKAEMIC FUSION GENE RUNX1/ETO BY SIRNA

HemaSphere
2022-06-23 | Journal article
Part of ISSN: 2572-9241
Contributors: L. Swart; P. Derevyanko; A. van Oort; M. Ashtiani; A. Krippner-Heidenreich; A. Koekman; C. Seinen; H. Issa; H. Blair; R. Schiffelers et al.
Source: Self-asserted source
Minoo Ashtiani

Epigenetic modifiers direct lineage switch in MLL-AF4 leukemia

Klinische Pädiatrie
2022-05 | Conference abstract
Part of ISSN: 1439-3824
Contributors: K Szoltysek; R Tirtakusuma; M Ashtiani; S Nakjang; V V Grinev; J Hehir-Kwa; EK Schweighart; S Bomken; O Heidenreich
Source: Self-asserted source
Minoo Ashtiani

Silencing the leukaemic fusion gene RUNX1/ETO by siRNA-loaded lipid nanoparticles restores myeloid differentiation

Klinische Pädiatrie
2022-05 | Conference abstract
Part of ISSN: 1439-3824
Contributors: L Swart; A van Oort; M Ashtiani; A Krippner-Heidenreich; S Kooijmans; D Tuk; A Koekman; C Seinen; H Issa; H Blair et al.
Source: Self-asserted source
Minoo Ashtiani

IMMAN: an R/Bioconductor package for Interolog protein network reconstruction, mapping and mining analysis

BMC Bioinformatics
2019-12 | Journal article
Part of ISSN: 1471-2105
Contributors: Minoo Ashtiani
Source: Self-asserted source
Minoo Ashtiani

CINNA: an R/CRAN package to decipher Central Informative Nodes in Network Analysis

Bioinformatics
2019-04-15 | Journal article
Part of ISSN: 1367-4803
Part of ISSN: 1460-2059
Contributors: Minoo Ashtiani
Source: Self-asserted source
Minoo Ashtiani

A systematic survey of centrality measures for protein-protein interaction networks

BMC Systems Biology
2018-12 | Journal article
Part of ISSN: 1752-0509
Contributors: Minoo Ashtiani
Source: Self-asserted source
Minoo Ashtiani

Valproic acid inhibits the protective effects of stromal cells against chemotherapy in breast cancer: Insights from proteomics and systems biology

Journal of Cellular Biochemistry
2018-11 | Journal article
Part of ISSN: 0730-2312
Part of ISSN: 1097-4644
Contributors: Minoo Ashtiani
Source: Self-asserted source
Minoo Ashtiani