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Loop profile: 887765

Biography

Dr. Selvaskandan is a clinical research fellow and a higher specialist nephrology trainee with an interest in glomerular diseases, medical technology and artificial intelligence in kidney disease. His research with the Mayer IgA nephropathy laboratories utilises methods including digital spatial profiling, laser capture micro-dissection, fluorescence-activated cell sorting and RNA-seq. Dr. Selvaskandan also has interests in applying artificial intelligence and machine learning methods to solve problems in clinical nephrology, and is developing skillsets in bioinformatics, python and R. Dr. Selvaskandan has secured over £700,000 in competitive funding for research, and has published widely in his fields of interest.

Dr. Selvaskandan supports a variety of clinical trials for kidney disease with Leicester's Renal Clinical Research Team, was chair of the College of Life Science's Fellows Forum, is an executive committee member of the UK Kidney Association's Renal SpR Club, and is on the executive board of the UK Kidney MedTech Network.

Activities

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Employment (7)

University of Leicester: Leicester, GB

2023-11-21 to present | Clinical Research Fellow (Cardiovascular Sciences)
Employment
Source: Self-asserted source
Haresh Selvaskandan

University Hospitals of Leicester NHS Trust: Leicester, Leicestershire, GB

2018-08-04 to present | Higher Specialist Nephrology Trainee (John Walls Renal Unit)
Employment
Source: Self-asserted source
Haresh Selvaskandan

University of Leicester: Leicester, Leicestershire, GB

2020-02-04 to 2023-08-31 | Kidney Research UK Clinical Research Training Fellow (Department of Cardiovascular Sciences)
Employment
Source: Self-asserted source
Haresh Selvaskandan

University of Leicester: Leicester, Leicestershire, GB

2015-08-04 to 2020-02-04 | Honorary Clinical Fellow (Infection, Immunity and Inflammation)
Employment
Source: Self-asserted source
Haresh Selvaskandan

University Hospitals of Leicester NHS Trust: Leicester, Leicester, GB

2015-08-04 to 2018-08-04 | NIHR Academic Clinical Fellow
Employment
Source: Self-asserted source
Haresh Selvaskandan

University Hospitals of Leicester NHS Trust: Leicester, Leicester, GB

2014-08-04 to 2015-08-04 | Academic Foundation Year Two Doctor
Employment
Source: Self-asserted source
Haresh Selvaskandan

Kettering General Hospital NHS Trust: Kettering, Northamptonshire, GB

2013-08-04 to 2014-08-04 | Foundation Year One Doctor
Employment
Source: Self-asserted source
Haresh Selvaskandan

Education and qualifications (7)

Royal College of Physicians : London, London, GB

2020 | Speciality Certificate Examination (Nephrology)
Education
Source: Self-asserted source
Haresh Selvaskandan

University of Leicester: Leicester, Leicestershire, GB

2015 to 2018 | Masters of Research Methods (MRes) (Infection, Immunity and Inflammation)
Education
Source: Self-asserted source
Haresh Selvaskandan

Royal College of Physicians: London, London, GB

2016-09 | MRCP (UK)
Education
Source: Self-asserted source
Haresh Selvaskandan

Swansea University: Swansea, Swansea, GB

2014 to 2015 | Post-graduate Certificate (Leadership and Management)
Education
Source: Self-asserted source
Haresh Selvaskandan

Cardiff University: Cardiff, Cardiff, GB

2013 to 2014 | Post-graduate Certificate (Medical Education)
Education
Source: Self-asserted source
Haresh Selvaskandan

University of Leicester: Leicester, Leicester, GB

2007-09 to 2013-07 | Bachelor of Medicine and Surgery (Hons) (Medical School)
Education
Source: Self-asserted source
Haresh Selvaskandan

University of Leicester: Leicester, Leicester, GB

2010-09 to 2011-07 | Bachelor of Science (Hons) (MRC Toxicology Unit)
Education
Source: Self-asserted source
Haresh Selvaskandan

Professional activities (8)

Renal Assosciation UK Renal SpR Club: Leicester, GB

2020-08 to present | East Midlands Representative/Communications Officer
Service
Source: Self-asserted source
Haresh Selvaskandan

UK Kidney Association: Cardiff, GB

2023 | UK Kidney Week 2023: Best Poster Prize (AKI category)
Distinction
Source: Self-asserted source
Haresh Selvaskandan

UK Kidney Association: Cardiff, GB

2023 | UK Kidney Week: Best poster prize (glomerular diseases)
Distinction
Source: Self-asserted source
Haresh Selvaskandan

Kidney Research UK: Peterborough, GB

2023 | Driving Discoveries: Best oral presentation prize
Distinction
Source: Self-asserted source
Haresh Selvaskandan

East Midlands Endocrinology Society: Leicester, GB

2020-09 | Best Presentation Prize
Distinction
Source: Self-asserted source
Haresh Selvaskandan

University Hospitals of Leicester NHS Trust: Leicester, Leicester, GB

2017-07 | David Ives Prize (1st Runner Up) (Department of Medicine)
Distinction
Source: Self-asserted source
Haresh Selvaskandan

University of Leicester Medical School: Leicester, Leicester, GB

2013-05 | Frank Harris Prize
Distinction
Source: Self-asserted source
Haresh Selvaskandan

University of Leicester: Leicester, Leicestershire, GB

2012 | Peer Assisted Learning Award
Distinction
Source: Self-asserted source
Haresh Selvaskandan

Funding (3)

Understanding the role of monocytes and glomerular endothelial cells in the formation of endocapillary hypercellularity in IgA nephropathy

2020-02 to 2023-07 | Grant
Kidney Research UK (Peterborough, GB)
GRANT_NUMBER:

TF_009_20181123
Source: Self-asserted source
Haresh Selvaskandan

East Midlands Trainee Bursary Award

2018-02 to 2018-02 | Award
University Hospitals of Leicester NHS Trust (Leicester, GB)
Source: Self-asserted source
Haresh Selvaskandan

Renal Association Student Bursary

2013-07 to 2013-08 | Award
Renal Assosciation United Kingdom (Leicester, GB)
Source: Self-asserted source
Haresh Selvaskandan

Works (34)

Distinct Neutralising and Complement-Fixing Antibody Responses Can Be Induced to the Same Antigen in Haemodialysis Patients After Immunisation with Different Vaccine Platforms

Vaccines
2024-12 | Journal article | Author
DOI: 10.3390/vaccines13010007
Contributors: Nadezhda Wall; Rachel Lamerton; Fiona Ashford; Marisol Perez-Toledo; Aleksandra Jasiulewicz; Gemma D Banham; Maddy L. Newby; Sian Faustini; Alex Richter; Haresh Selvaskandan et al.
Source: check_circle
Multidisciplinary Digital Publishing Institute

Novel Treatment Paradigms: Primary IgA Nephropathy

Kidney International Reports
2023-12 | Journal article
DOI: 10.1016/j.ekir.2023.11.026
Part of ISSN: 2468-0249
Contributors: Haresh Selvaskandan; Jonathan Barratt; Chee Kay Cheung
Source: Self-asserted source
Haresh Selvaskandan

#3979 DIGITAL SPATIAL PROFILING CAN BE USED TO STUDY GLOMERULAR ENDOTHELIAL CELLS IN IGA NEPHROPATHY

Nephrology Dialysis Transplantation
2023-06-14 | Journal article
DOI: 10.1093/ndt/gfad063c_3979
Part of ISSN: 0931-0509
Part of ISSN: 1460-2385
Contributors: Haresh Selvaskandan; Charlotte Boys; Izabella Pawluczyk; Jonathan Barratt
Source: Self-asserted source
Haresh Selvaskandan

Clinical application of microRNAs in glomerular diseases.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
2023-05-01 | Journal article | Author
DOI: 10.1093/ndt/gfac230
PMID: 35906877
Contributors: Haresh Selvaskandan; Pawluczyk I; Jonathan Barratt
Source: Self-asserted source
Haresh Selvaskandan

WCN23-0066 Identifying druggable pathways in IgA Nephropathy using spatial transcriptomics

Kidney International Reports
2023-03 | Journal article
DOI: 10.1016/j.ekir.2023.02.113
Part of ISSN: 2468-0249
Contributors: H. SELVASKANDAN; I. Pawluczyk; J. Barratt
Source: Self-asserted source
Haresh Selvaskandan

WCN23-0139 Leveraging modern machine learning tools to predict outcomes of in-patient acute kidney injury

Kidney International Reports
2023-03 | Journal article
DOI: 10.1016/j.ekir.2023.02.220
Part of ISSN: 2468-0249
Contributors: H. SELVASKANDAN; T. Gaultney; D. Heath; S. Linfoot; G. Xu
Source: Self-asserted source
Haresh Selvaskandan

IgA nephropathy: an overview of drug treatments in clinical trials.

Expert opinion on investigational drugs
2022-12-01 | Journal article | Author
DOI: 10.1080/13543784.2022.2160315
PMID: 36588457
Contributors: Haresh Selvaskandan; Gonzalez-Martin G; Jonathan Barratt; Chee Kay Cheung
Source: Self-asserted source
Haresh Selvaskandan

Risk factors associated with COVID-19 severity among patients on maintenance haemodialysis: a retrospective multicentre cross-sectional study in the UK.

BMJ open
2022-05-30 | Journal article | Author
DOI: 10.1136/bmjopen-2021-054869
PMID: 35636784
PMC: PMC9152624
Contributors: Haresh Selvaskandan; Katherine Leigh Hull; Sherna Adenwalla; Ahmed S; Cusu MC; Matthew Graham-Brown; Gray L; Hall M; Hamer R; Kanbar A et al.
Source: Self-asserted source
Haresh Selvaskandan

Regional variations in nephrology trainee confidence with clinical skills may relate to the availability of local training opportunities in the UK: results from a national survey.

Clinical and experimental nephrology
2022-05-07 | Journal article | Author
DOI: 10.1007/s10157-022-02228-7
PMID: 35524893
PMC: PMC9077353
Contributors: Haresh Selvaskandan; Baharani J; Hamer R
Source: Self-asserted source
Haresh Selvaskandan

Acute respiratory distress syndrome driven by severe hypercalcemia and acute kidney injury: A case report and literature review of a rare, life-threatening complication.

Clinical nephrology. Case studies
2022-01-24 | Journal article
DOI: 10.5414/cncs110464
PMID: 35106272
PMC: PMC8802067
Contributors: Selvaskandan H; Hull K; Gregory R; Daniel Pan; Macriyiannis T; Briggs J; Richards C; Mason C; Jesus-Silva J; Bell R
Source: Self-asserted source
Haresh Selvaskandan

Burnout and long COVID among the UK nephrology workforce: results from a national survey investigating the impact of COVID-19 on working lives.

Clinical kidney journal
2021-12-13 | Journal article
DOI: 10.1093/ckj/sfab264
PMID: 35198158
PMC: PMC8754810
Contributors: Selvaskandan H; Ailish Nimmo; Manuela Savino; Afuwape S; Brand S; Graham-Brown M; Medcalf J; Paul Cockwell; Hannah Beckwith
Source: Self-asserted source
Haresh Selvaskandan

Immunological drivers of IgA nephropathy: Exploring the mucosa-kidney link.

International journal of immunogenetics
2021-11-24 | Journal article | Author
DOI: 10.1111/iji.12561
PMID: 34821031
Contributors: Haresh Selvaskandan; Jonathan Barratt; Chee Kay Cheung
Source: Self-asserted source
Haresh Selvaskandan

New Insights into the Pathogenesis and Treatment Strategies in IgA Nephropathy.

Glomerular diseases
2021-10-01 | Journal article
DOI: 10.1159/000519973
PMID: 36751267
PMC: PMC9677740
Contributors: Scionti K; Molyneux K; Selvaskandan H; Jonathan Barratt; Chee Kay Cheung
Source: Self-asserted source
Haresh Selvaskandan

A Pilot Study to Predict Risk of IgA Nephropathy Progression Based on miR-204 Expression.

Kidney international reports
2021-06-05 | Journal article
DOI: 10.1016/j.ekir.2021.05.018
PMID: 34386667
PMC: PMC8343780
Contributors: Pawluczyk I; Nicholson M; Barbour S; Er L; Selvaskandan H; Bhachu JS; Jonathan Barratt
Source: Self-asserted source
Haresh Selvaskandan

The Non-Coding RNA Landscape in IgA Nephropathy-Where Are We in 2021?

Journal of clinical medicine
2021-05-28 | Journal article
DOI: 10.3390/jcm10112369
PMID: 34071162
PMC: PMC8198207
Contributors: Pawluczyk IZA; Selvaskandan H; Jonathan Barratt
Source: Self-asserted source
Haresh Selvaskandan

An Ethnic Variation in the Acceptance of Biological Disease-Modifying Therapies: A University Hospital Experience.

Cureus
2021-05-27 | Journal article
DOI: 10.7759/cureus.15270
PMID: 34194874
PMC: PMC8234561
Contributors: Selvaskandan H; Moorthy A
Source: Self-asserted source
Haresh Selvaskandan

Seroprevalence of antibody to S1 spike protein following vaccination against COVID-19 in patients receiving hemodialysis: a call to arms.

Kidney international
2021-04-20 | Journal article
DOI: 10.1016/j.kint.2021.04.008
PMID: 33887316
PMC: PMC8055918
Source: Self-asserted source
Haresh Selvaskandan

Impact of the COVID-19 Pandemic on Training, Morale and Well-Being Among the UK Renal Workforce.

Kidney international reports
2021-03-15 | Journal article
DOI: 10.1016/j.ekir.2021.03.004
PMID: 34013121
PMC: PMC8116903
Contributors: Hannah Beckwith; Ailish Nimmo; Manuela Savino; Selvaskandan H; Matthew Graham-Brown; Medcalf J; Paul Cockwell; UK Renal SpR Club and Renal Association
Source: Self-asserted source
Haresh Selvaskandan

Monitoring Immune Responses in IgA Nephropathy: Biomarkers to Guide Management.

Frontiers in immunology
2020-10-06 | Journal article
DOI: 10.3389/fimmu.2020.572754
PMID: 33123151
PMC: PMC7572847
Contributors: Selvaskandan H; Shi S; Twaij S; Chee Kay Cheung; Jonathan Barratt
Source: Self-asserted source
Haresh Selvaskandan

The Exclusion of Patients with CKD in Prospectively Registered Interventional Trials for COVID-19-a Rapid Review of International Registry Data.

Journal of the American Society of Nephrology : JASN
2020-09-08 | Journal article
DOI: 10.1681/asn.2020060877
PMID: 32900842
Source: Self-asserted source
Haresh Selvaskandan

Macrophage interactions with collecting duct epithelial cells are capable of driving tubulointerstitial inflammation and fibrosis in immunoglobulin A nephropathy.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
2020-08-23 | Journal article
DOI: 10.1093/ndt/gfaa079
PMID: 32830258
Source: Self-asserted source
Haresh Selvaskandan

Inhibition of the Lectin Pathway of the Complement System as a Novel Approach in the Management of IgA Vasculitis-Associated Nephritis.

Nephron
2020-07-28 | Journal article
DOI: 10.1159/000508841
PMID: 32721954
Source: Self-asserted source
Haresh Selvaskandan

Diabetic myonecrosis: A case series of two dialysis-dependent patients.

Clinical nephrology. Case studies
2019-07-12 | Journal article
DOI: 10.5414/cncs109626
PMID: 31321201
PMC: PMC6637392
Source: Self-asserted source
Haresh Selvaskandan

High-dose oral linezolid achieved rapid clinical and microbiological recovery in a severely overweight male with long-standing infected ulcers.

The Journal of antimicrobial chemotherapy
2019-06-01 | Journal article
DOI: 10.1093/jac/dkz071
PMID: 30783670
Source: Self-asserted source
Haresh Selvaskandan

The Case | Microangiopathic hemolytic anemia in a young female.

Kidney international
2019-05-01 | Journal article
DOI: 10.1016/j.kint.2018.11.020
PMID: 31010484
Source: Self-asserted source
Haresh Selvaskandan

New strategies and perspectives on managing IgA nephropathy.

Clinical and experimental nephrology
2019-02-13 | Journal article
DOI: 10.1007/s10157-019-01700-1
PMID: 30756248
PMC: PMC6469670
Source: Self-asserted source
Haresh Selvaskandan

Macrophage-Derived Products Induce Pro-Inflammatory and Pro-Fibrotic Responses in Renal Collecting Ducts: A Potential Role in the Pathogenesis of IgA Nephropathy?

Kidney Diseases
2018 | Conference abstract
DOI: 10.1159/000492806
Part of ISSN: 2296-9381
Part of ISSN: 2296-9357
Source: Self-asserted source
Haresh Selvaskandan

083 Is there an ethnic variation in acceptance of biologic therapy among axial spondyloathropathy patients? A university teaching hospital experience

Rheumatology
2018-04-01 | Conference abstract
DOI: 10.1093/rheumatology/key075.307
Part of ISSN: 1462-0324
Part of ISSN: 1462-0332
Source: Self-asserted source
Haresh Selvaskandan

MicroRNAs: a new avenue to understand, investigate and treat immunoglobulin A nephropathy?

Clinical kidney journal
2017-09-23 | Journal article
DOI: 10.1093/ckj/sfx096
PMID: 29423198
PMC: PMC5798124
Source: Self-asserted source
Haresh Selvaskandan

IgA nephropathy: driving innovation with a rare renal disease registry

Journal of Kidney Care
2017-07-02 | Journal article
DOI: 10.12968/jokc.2017.2.4.205
Part of ISSN: 2397-9534
Part of ISSN: 2397-9542
Source: Self-asserted source
Haresh Selvaskandan

Acoustic trauma slows AMPA receptor-mediated EPSCs in the auditory brainstem, reducing GluA4 subunit expression as a mechanism to rescue binaural function.

The Journal of physiology
2016-06-09 | Journal article
DOI: 10.1113/jp271929
PMID: 27104476
PMC: PMC4929335
Source: Self-asserted source
Haresh Selvaskandan

Smartphones and medical education.

The clinical teacher
2014-10-01 | Journal article
DOI: 10.1111/tct.12169
PMID: 25212943
Source: Self-asserted source
Haresh Selvaskandan

The prescribing skills assessment.

The clinical teacher
2014-02-01 | Journal article
DOI: 10.1111/tct.12133
PMID: 24405922
Source: Self-asserted source
Haresh Selvaskandan

The importance of counseling in young, female epileptic patients.

Journal of pediatric neurosciences
2013-09-01 | Journal article
DOI: 10.4103/1817-1745.123720
PMID: 24470836
PMC: PMC3888059
Source: Self-asserted source
Haresh Selvaskandan

Peer review (1 review for 1 publication/grant)

Review activity for The Lancet. (1)
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