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Works (21)

Application of fluorescent dextrans to the brain surface under constant pressure reveals AQP4-independent solute uptake

Journal of General Physiology
2021-08-02 | Journal article
DOI: 10.1085/jgp.202112898
Contributors: Alex J. Smith; Gokhan Akdemir; Meetu Wadhwa; Dan Song; Alan S. Verkman
Source: check_circle
Crossref

Aquaporin-4 reduces neuropathology in a mouse model of Alzheimer’s disease by remodeling peri-plaque astrocyte structure

Acta Neuropathologica Communications
2019-12 | Journal article
DOI: 10.1186/s40478-019-0728-0
Contributors: Alex J. Smith; Tianjiao Duan; Alan S. Verkman
Source: check_circle
Crossref

CrossTalk opposing view: Going against the flow: interstitial solute transport in brain is diffusive and aquaporin‐4 independent

The Journal of Physiology
2019-09 | Journal article
DOI: 10.1113/JP277636
Contributors: Alex J. Smith; Alan S. Verkman
Source: check_circle
Crossref

Rebuttal from Alex J. Smith and Alan S. Verkman

The Journal of Physiology
2019-09 | Journal article
DOI: 10.1113/JP278461
Contributors: Alex J. Smith; Alan S. Verkman
Source: check_circle
Crossref

Test of the 'glymphatic' hypothesis demonstrates diffusive and aquaporin-4-independent solute transport in rodent brain parenchyma

eLife
2017-08-21 | Journal article
DOI: 10.7554/eLife.27679
Contributors: Alex J Smith; Xiaoming Yao; James A Dix; Byung-Ju Jin; Alan S Verkman
Source: check_circle
Crossref

Aquaporin Water Channels and Hydrocephalus.

2016-12 | Journal article
PMID: 27978530
Contributors: Verkman AS; Tradtrantip L; Smith AJ; Yao X
Source: Self-asserted source
Alex Smith via Europe PubMed Central

Spatial model of convective solute transport in brain extracellular space does not support a "glymphatic" mechanism.

2016-12 | Journal article
DOI: 10.1085/jgp.201611684
PMID: 27836940
Contributors: Jin BJ; Smith AJ; Verkman AS
Source: Self-asserted source
Alex Smith via Europe PubMed Central

Superresolution Imaging of Aquaporin-4 Cluster Size in Antibody-Stained Paraffin Brain Sections.

2015-12 | Journal article
DOI: 10.1016/j.bpj.2015.10.047
PMID: 26682810
PMC: PMC4699884
Contributors: Smith AJ; Verkman AS
Source: Self-asserted source
Alex Smith via Europe PubMed Central

Aquaporin-4 regulates the velocity and frequency of cortical spreading depression in mice.

2015-10 | Journal article
DOI: 10.1002/glia.22853
PMID: 25944186
Contributors: Yao X; Smith AJ; Jin BJ; Zador Z; Manley GT; Verkman AS
Source: Self-asserted source
Alex Smith via Europe PubMed Central

Muddying the water in brain edema?

2015-06 | Journal article
DOI: 10.1016/j.tins.2015.04.006
PMID: 25980601
Contributors: Smith AJ; Jin BJ; Verkman AS
Source: Self-asserted source
Alex Smith via Europe PubMed Central

Human immunoglobulin G reduces the pathogenicity of aquaporin-4 autoantibodies in neuromyelitis optica.

2014-05 | Journal article
DOI:

10.1016/j.expneurol.2014.03.004

PMID:

24636863
Contributors: Ratelade J; Smith AJ; Verkman AS
Source: Self-asserted source
Alex Smith via Europe PubMed Central

Aggregation state determines the localization and function of M1- and M23-aquaporin-4 in astrocytes.

2014-02 | Journal article
DOI:

10.1083/jcb.201308118

PMID:

24515349

PMC:

PMC3926963
Contributors: Smith AJ; Jin BJ; Ratelade J; Verkman AS
Source: Self-asserted source
Alex Smith via Europe PubMed Central

Cholesterol and F-actin are required for clustering of recycling synaptic vesicle proteins in the presynaptic plasma membrane.

2014-02 | Journal article
DOI:

10.1113/jphysiol.2013.265447

PMID:

24297851
Contributors: Dason JS; Smith AJ; Marin L; Charlton MP
Source: Self-asserted source
Alex Smith via Europe PubMed Central

Vesicular sterols are essential for synaptic vesicle cycling.

2010-11 | Journal article
DOI:

10.1523/JNEUROSCI.4132-10.2010

PMID:

21106824
Contributors: Dason JS; Smith AJ; Marin L; Charlton MP
Source: Self-asserted source
Alex Smith via Europe PubMed Central

Cholesterol-dependent kinase activity regulates transmitter release from cerebellar synapses.

2010-04 | Journal article
DOI:

10.1523/JNEUROSCI.0170-10.2010

PMID:

20427669
Contributors: Smith AJ; Sugita S; Charlton MP
Source: Self-asserted source
Alex Smith via Europe PubMed Central

Facilitating exchange: activity-dependent regulation of presynaptic Na+/Ca2+ exchange.

2008-04 | Journal article
DOI:

10.1113/jphysiol.2008.151837

PMID:

18308821
Contributors: Silverman-Gavrila LB; Smith AJ
Source: Self-asserted source
Alex Smith via Europe PubMed Central

Reaction diffusion modeling of calcium dynamics with realistic ER geometry.

2006-07 | Journal article
DOI:

10.1529/biophysj.105.075036

PMID:

16617072

PMC:

PMC1483115
Contributors: Means S; Smith AJ; Shepherd J; Shadid J; Fowler J; Wojcikiewicz RJ; Mazel T; Smith GD; Wilson BS
Source: Self-asserted source
Alex Smith via Europe PubMed Central

Dysregulated FcepsilonRI signaling and altered Fyn and SHIP activities in Lyn-deficient mast cells.

2004-07 | Journal article
DOI:

10.4049/jimmunol.173.1.100

PMID:

15210764
Contributors: Hernandez-Hansen V; Smith AJ; Surviladze Z; Chigaev A; Mazel T; Kalesnikoff J; Lowell CA; Krystal G; Sklar LA; Wilson BS et al.
Source: Self-asserted source
Alex Smith via Europe PubMed Central

Microtubule-dependent transport of secretory vesicles in RBL-2H3 cells.

2003-05 | Journal article
DOI:

10.1034/j.1600-0854.2003.00084.x

PMID:

12713658
Contributors: Smith AJ; Pfeiffer JR; Zhang J; Martinez AM; Griffiths GM; Wilson BS
Source: Self-asserted source
Alex Smith via Europe PubMed Central

p110beta and p110delta phosphatidylinositol 3-kinases up-regulate Fc(epsilon)RI-activated Ca2+ influx by enhancing inositol 1,4,5-trisphosphate production.

2001-05 | Journal article
DOI:

10.1074/jbc.M100417200

PMID:

11279065
Contributors: Smith AJ; Surviladze Z; Gaudet EA; Backer JM; Mitchell CA; Wilson BS
Source: Self-asserted source
Alex Smith via Europe PubMed Central

Calcium-dependent clustering of inositol 1,4,5-trisphosphate receptors.

1998-06 | Journal article
DOI:

10.1091/mbc.9.6.1465

PMID:

9614187

PMC:

PMC25370
Contributors: Wilson BS; Pfeiffer JR; Smith AJ; Oliver JM; Oberdorf JA; Wojcikiewicz RJ
Source: Self-asserted source
Alex Smith via Europe PubMed Central
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