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Loop profile: 782003
Scopus Author ID: 57191922655

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Employment (1)

The Wistar Institute: Philadelphia, Pennsylvania, US

2015-11-01 to present
Employment
Source: Self-asserted source
Shuai Wu

Education and qualifications (1)

Shanghai Institutes for Biological Sciences: Shanghai, Shanghai, CN

2005-09 to 2011-06
Education
Source: Self-asserted source
Shuai Wu

Works (45)

Data from HDAC6 Inhibition Synergizes with Anti-PD-L1 Therapy in ARID1A-Inactivated Ovarian Cancer

2023-03-31 | Preprint
DOI: 10.1158/0008-5472.c.6512272
Contributors: Takeshi Fukumoto; Nail Fatkhutdinov; Joseph A. Zundell; Evgenii N. Tcyganov; Timothy Nacarelli; Sergey Karakashev; Shuai Wu; Qin Liu; Dmitry I. Gabrilovich; Rugang Zhang
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Crossref

Data from HDAC6 Inhibition Synergizes with Anti-PD-L1 Therapy in ARID1A-Inactivated Ovarian Cancer

2023-03-31 | Preprint
DOI: 10.1158/0008-5472.c.6512272.v1
Contributors: Takeshi Fukumoto; Nail Fatkhutdinov; Joseph A. Zundell; Evgenii N. Tcyganov; Timothy Nacarelli; Sergey Karakashev; Shuai Wu; Qin Liu; Dmitry I. Gabrilovich; Rugang Zhang
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Crossref

Data from Targeting the IRE1α/XBP1 Endoplasmic Reticulum Stress Response Pathway in <i>ARID1A</i>-Mutant Ovarian Cancers

2023-03-31 | Preprint
DOI: 10.1158/0008-5472.c.6513601
Contributors: Joseph A. Zundell; Takeshi Fukumoto; Jianhuang Lin; Nail Fatkhudinov; Timothy Nacarelli; Andrew V. Kossenkov; Qin Liu; Joel Cassel; Chih-Chi Andrew Hu; Shuai Wu et al.
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Data from Targeting the IRE1α/XBP1 Endoplasmic Reticulum Stress Response Pathway in <i>ARID1A</i>-Mutant Ovarian Cancers

2023-03-31 | Preprint
DOI: 10.1158/0008-5472.c.6513601.v1
Contributors: Joseph A. Zundell; Takeshi Fukumoto; Jianhuang Lin; Nail Fatkhudinov; Timothy Nacarelli; Andrew V. Kossenkov; Qin Liu; Joel Cassel; Chih-Chi Andrew Hu; Shuai Wu et al.
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Crossref

Figure S1 from HDAC6 Inhibition Synergizes with Anti-PD-L1 Therapy in ARID1A-Inactivated Ovarian Cancer

2023-03-31 | Preprint
DOI: 10.1158/0008-5472.22426255
Contributors: Takeshi Fukumoto; Nail Fatkhutdinov; Joseph A. Zundell; Evgenii N. Tcyganov; Timothy Nacarelli; Sergey Karakashev; Shuai Wu; Qin Liu; Dmitry I. Gabrilovich; Rugang Zhang
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Figure S1 from HDAC6 Inhibition Synergizes with Anti-PD-L1 Therapy in ARID1A-Inactivated Ovarian Cancer

2023-03-31 | Preprint
DOI: 10.1158/0008-5472.22426255.v1
Contributors: Takeshi Fukumoto; Nail Fatkhutdinov; Joseph A. Zundell; Evgenii N. Tcyganov; Timothy Nacarelli; Sergey Karakashev; Shuai Wu; Qin Liu; Dmitry I. Gabrilovich; Rugang Zhang
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Figure S1 from Targeting the IRE1α/XBP1 Endoplasmic Reticulum Stress Response Pathway in <i>ARID1A</i>-Mutant Ovarian Cancers

2023-03-31 | Preprint
DOI: 10.1158/0008-5472.22430368
Contributors: Joseph A. Zundell; Takeshi Fukumoto; Jianhuang Lin; Nail Fatkhudinov; Timothy Nacarelli; Andrew V. Kossenkov; Qin Liu; Joel Cassel; Chih-Chi Andrew Hu; Shuai Wu et al.
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Figure S1 from Targeting the IRE1α/XBP1 Endoplasmic Reticulum Stress Response Pathway in <i>ARID1A</i>-Mutant Ovarian Cancers

2023-03-31 | Preprint
DOI: 10.1158/0008-5472.22430368.v1
Contributors: Joseph A. Zundell; Takeshi Fukumoto; Jianhuang Lin; Nail Fatkhudinov; Timothy Nacarelli; Andrew V. Kossenkov; Qin Liu; Joel Cassel; Chih-Chi Andrew Hu; Shuai Wu et al.
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Figure S2 from HDAC6 Inhibition Synergizes with Anti-PD-L1 Therapy in ARID1A-Inactivated Ovarian Cancer

2023-03-31 | Preprint
DOI: 10.1158/0008-5472.22426252
Contributors: Takeshi Fukumoto; Nail Fatkhutdinov; Joseph A. Zundell; Evgenii N. Tcyganov; Timothy Nacarelli; Sergey Karakashev; Shuai Wu; Qin Liu; Dmitry I. Gabrilovich; Rugang Zhang
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Crossref

Figure S2 from HDAC6 Inhibition Synergizes with Anti-PD-L1 Therapy in ARID1A-Inactivated Ovarian Cancer

2023-03-31 | Preprint
DOI: 10.1158/0008-5472.22426252.v1
Contributors: Takeshi Fukumoto; Nail Fatkhutdinov; Joseph A. Zundell; Evgenii N. Tcyganov; Timothy Nacarelli; Sergey Karakashev; Shuai Wu; Qin Liu; Dmitry I. Gabrilovich; Rugang Zhang
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Figure S2 from Targeting the IRE1α/XBP1 Endoplasmic Reticulum Stress Response Pathway in <i>ARID1A</i>-Mutant Ovarian Cancers

2023-03-31 | Preprint
DOI: 10.1158/0008-5472.22430365
Contributors: Joseph A. Zundell; Takeshi Fukumoto; Jianhuang Lin; Nail Fatkhudinov; Timothy Nacarelli; Andrew V. Kossenkov; Qin Liu; Joel Cassel; Chih-Chi Andrew Hu; Shuai Wu et al.
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Figure S2 from Targeting the IRE1α/XBP1 Endoplasmic Reticulum Stress Response Pathway in <i>ARID1A</i>-Mutant Ovarian Cancers

2023-03-31 | Preprint
DOI: 10.1158/0008-5472.22430365.v1
Contributors: Joseph A. Zundell; Takeshi Fukumoto; Jianhuang Lin; Nail Fatkhudinov; Timothy Nacarelli; Andrew V. Kossenkov; Qin Liu; Joel Cassel; Chih-Chi Andrew Hu; Shuai Wu et al.
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Crossref

Figure S3 from HDAC6 Inhibition Synergizes with Anti-PD-L1 Therapy in ARID1A-Inactivated Ovarian Cancer

2023-03-31 | Preprint
DOI: 10.1158/0008-5472.22426249
Contributors: Takeshi Fukumoto; Nail Fatkhutdinov; Joseph A. Zundell; Evgenii N. Tcyganov; Timothy Nacarelli; Sergey Karakashev; Shuai Wu; Qin Liu; Dmitry I. Gabrilovich; Rugang Zhang
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Crossref

Figure S3 from HDAC6 Inhibition Synergizes with Anti-PD-L1 Therapy in ARID1A-Inactivated Ovarian Cancer

2023-03-31 | Preprint
DOI: 10.1158/0008-5472.22426249.v1
Contributors: Takeshi Fukumoto; Nail Fatkhutdinov; Joseph A. Zundell; Evgenii N. Tcyganov; Timothy Nacarelli; Sergey Karakashev; Shuai Wu; Qin Liu; Dmitry I. Gabrilovich; Rugang Zhang
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Crossref

Figure S3 from Targeting the IRE1α/XBP1 Endoplasmic Reticulum Stress Response Pathway in <i>ARID1A</i>-Mutant Ovarian Cancers

2023-03-31 | Preprint
DOI: 10.1158/0008-5472.22430362
Contributors: Joseph A. Zundell; Takeshi Fukumoto; Jianhuang Lin; Nail Fatkhudinov; Timothy Nacarelli; Andrew V. Kossenkov; Qin Liu; Joel Cassel; Chih-Chi Andrew Hu; Shuai Wu et al.
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Figure S3 from Targeting the IRE1α/XBP1 Endoplasmic Reticulum Stress Response Pathway in <i>ARID1A</i>-Mutant Ovarian Cancers

2023-03-31 | Preprint
DOI: 10.1158/0008-5472.22430362.v1
Contributors: Joseph A. Zundell; Takeshi Fukumoto; Jianhuang Lin; Nail Fatkhudinov; Timothy Nacarelli; Andrew V. Kossenkov; Qin Liu; Joel Cassel; Chih-Chi Andrew Hu; Shuai Wu et al.
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Figure S4 from Targeting the IRE1α/XBP1 Endoplasmic Reticulum Stress Response Pathway in <i>ARID1A</i>-Mutant Ovarian Cancers

2023-03-31 | Preprint
DOI: 10.1158/0008-5472.22430359
Contributors: Joseph A. Zundell; Takeshi Fukumoto; Jianhuang Lin; Nail Fatkhudinov; Timothy Nacarelli; Andrew V. Kossenkov; Qin Liu; Joel Cassel; Chih-Chi Andrew Hu; Shuai Wu et al.
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Figure S4 from Targeting the IRE1α/XBP1 Endoplasmic Reticulum Stress Response Pathway in <i>ARID1A</i>-Mutant Ovarian Cancers

2023-03-31 | Preprint
DOI: 10.1158/0008-5472.22430359.v1
Contributors: Joseph A. Zundell; Takeshi Fukumoto; Jianhuang Lin; Nail Fatkhudinov; Timothy Nacarelli; Andrew V. Kossenkov; Qin Liu; Joel Cassel; Chih-Chi Andrew Hu; Shuai Wu et al.
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Figure S5 from Targeting the IRE1α/XBP1 Endoplasmic Reticulum Stress Response Pathway in <i>ARID1A</i>-Mutant Ovarian Cancers

2023-03-31 | Preprint
DOI: 10.1158/0008-5472.22430356
Contributors: Joseph A. Zundell; Takeshi Fukumoto; Jianhuang Lin; Nail Fatkhudinov; Timothy Nacarelli; Andrew V. Kossenkov; Qin Liu; Joel Cassel; Chih-Chi Andrew Hu; Shuai Wu et al.
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Figure S5 from Targeting the IRE1α/XBP1 Endoplasmic Reticulum Stress Response Pathway in <i>ARID1A</i>-Mutant Ovarian Cancers

2023-03-31 | Preprint
DOI: 10.1158/0008-5472.22430356.v1
Contributors: Joseph A. Zundell; Takeshi Fukumoto; Jianhuang Lin; Nail Fatkhudinov; Timothy Nacarelli; Andrew V. Kossenkov; Qin Liu; Joel Cassel; Chih-Chi Andrew Hu; Shuai Wu et al.
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Figure S6 from Targeting the IRE1α/XBP1 Endoplasmic Reticulum Stress Response Pathway in <i>ARID1A</i>-Mutant Ovarian Cancers

2023-03-31 | Preprint
DOI: 10.1158/0008-5472.22430353
Contributors: Joseph A. Zundell; Takeshi Fukumoto; Jianhuang Lin; Nail Fatkhudinov; Timothy Nacarelli; Andrew V. Kossenkov; Qin Liu; Joel Cassel; Chih-Chi Andrew Hu; Shuai Wu et al.
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Figure S6 from Targeting the IRE1α/XBP1 Endoplasmic Reticulum Stress Response Pathway in <i>ARID1A</i>-Mutant Ovarian Cancers

2023-03-31 | Preprint
DOI: 10.1158/0008-5472.22430353.v1
Contributors: Joseph A. Zundell; Takeshi Fukumoto; Jianhuang Lin; Nail Fatkhudinov; Timothy Nacarelli; Andrew V. Kossenkov; Qin Liu; Joel Cassel; Chih-Chi Andrew Hu; Shuai Wu et al.
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Supplementary Figure Legends from HDAC6 Inhibition Synergizes with Anti-PD-L1 Therapy in ARID1A-Inactivated Ovarian Cancer

2023-03-31 | Preprint
DOI: 10.1158/0008-5472.22426246
Contributors: Takeshi Fukumoto; Nail Fatkhutdinov; Joseph A. Zundell; Evgenii N. Tcyganov; Timothy Nacarelli; Sergey Karakashev; Shuai Wu; Qin Liu; Dmitry I. Gabrilovich; Rugang Zhang
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Crossref

Supplementary Figure Legends from HDAC6 Inhibition Synergizes with Anti-PD-L1 Therapy in ARID1A-Inactivated Ovarian Cancer

2023-03-31 | Preprint
DOI: 10.1158/0008-5472.22426246.v1
Contributors: Takeshi Fukumoto; Nail Fatkhutdinov; Joseph A. Zundell; Evgenii N. Tcyganov; Timothy Nacarelli; Sergey Karakashev; Shuai Wu; Qin Liu; Dmitry I. Gabrilovich; Rugang Zhang
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Crossref

Targeting the IRE1α/XBP1 Endoplasmic Reticulum Stress Response Pathway in ARID1A-Mutant Ovarian Cancers

Cancer Research
2021-10-15 | Journal article
DOI: 10.1158/0008-5472.CAN-21-1545
Contributors: Joseph A. Zundell; Takeshi Fukumoto; Jianhuang Lin; Nail Fatkhudinov; Timothy Nacarelli; Andrew V. Kossenkov; Qin Liu; Joel Cassel; Chih-Chi Andrew Hu; Shuai Wu et al.
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Targeting the IRE1α/XBP1s pathway suppresses CARM1-expressing ovarian cancer

Nature Communications
2021-09-07 | Journal article
DOI: 10.1038/s41467-021-25684-3
Contributors: Jianhuang Lin; Heng Liu; Takeshi Fukumoto; Joseph Zundell; Qingqing Yan; Chih-Hang Anthony Tang; Shuai Wu; Wei Zhou; Dajiang Guo; Sergey Karakashev et al.
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Crossref

Targeting glutamine dependence through GLS1 inhibition suppresses ARID1A-inactivated clear cell ovarian carcinoma

Nature Cancer
2021-01-11 | Journal article
DOI: 10.1038/s43018-020-00160-x
Contributors: Shuai Wu; Takeshi Fukumoto; Jianhuang Lin; Timothy Nacarelli; Yemin Wang; Dionzie Ong; Heng Liu; Nail Fatkhutdinov; Joseph A. Zundell; Sergey Karakashev et al.
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Crossref

ARID1A spatially partitions interphase chromosomes

Science Advances
2019 | Journal article
DOI: 10.1126/sciadv.aaw5294
EID:

2-s2.0-85066314843
Contributors: Wu, S.; Fatkhutdinov, N.; Rosin, L.; Luppino, J.M.; Iwasaki, O.; Tanizawa, H.; Tang, H.-Y.; Kossenkov, A.V.; Gardini, A.; Noma, K.-I. et al.
Source: Self-asserted source
Shuai Wu via Scopus - Elsevier
grade
Preferred source (of 2)‎

N<sup>6</sup>-methylation of adenosine of FZD10 mRNA contributes to PARP inhibitor resistance

Cancer Research
2019 | Journal article
DOI: 10.1158/0008-5472.CAN-18-3592
EID:

2-s2.0-85066481083
Contributors: Fukumoto, T.; Zhu, H.; Nacarelli, T.; Karakashev, S.; Fatkhutdinov, N.; Wu, S.; Liu, P.; Kossenkov, A.V.; Showe, L.C.; Jean, S. et al.
Source: Self-asserted source
Shuai Wu via Scopus - Elsevier
grade
Preferred source (of 2)‎

NAD <sup>+</sup> metabolism governs the proinflammatory senescence-associated secretome

Nature Cell Biology
2019 | Journal article
DOI: 10.1038/s41556-019-0287-4
EID:

2-s2.0-85061731316
Contributors: Nacarelli, T.; Lau, L.; Fukumoto, T.; Zundell, J.; Fatkhutdinov, N.; Wu, S.; Aird, K.M.; Iwasaki, O.; Kossenkov, A.V.; Schultz, D. et al.
Source: Self-asserted source
Shuai Wu via Scopus - Elsevier

HDAC6 Inhibition Synergizes with Anti-PD-L1 Therapy in ARID1A-Inactivated Ovarian Cancer

Cancer Research
2019-11-01 | Journal article
DOI: 10.1158/0008-5472.CAN-19-1302
Contributors: Takeshi Fukumoto; Nail Fatkhutdinov; Joseph A. Zundell; Evgenii N. Tcyganov; Timothy Nacarelli; Sergey Karakashev; Shuai Wu; Qin Liu; Dmitry I. Gabrilovich; Rugang Zhang
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Crossref

CARM1-expressing ovarian cancer depends on the histone methyltransferase EZH2 activity

Nature Communications
2018 | Journal article
DOI: 10.1038/s41467-018-03031-3
EID:

2-s2.0-85042019205
Contributors: Karakashev, S.; Zhu, H.; Wu, S.; Yokoyama, Y.; Bitler, B.G.; Park, P.-H.; Lee, J.-H.; Kossenkov, A.V.; Gaonkar, K.S.; Yan, H. et al.
Source: Self-asserted source
Shuai Wu via Scopus - Elsevier

Repurposing Pan-HDAC Inhibitors for ARID1A-Mutated Ovarian Cancer

Cell Reports
2018 | Journal article
DOI: 10.1016/j.celrep.2018.03.019
EID:

2-s2.0-85043984145
Contributors: Fukumoto, T.; Park, P.H.; Wu, S.; Fatkhutdinov, N.; Karakashev, S.; Nacarelli, T.; Kossenkov, A.V.; Speicher, D.W.; Jean, S.; Zhang, L. et al.
Source: Self-asserted source
Shuai Wu via Scopus - Elsevier

SWI/SNF catalytic subunits’ switch drives resistance to EZH2 inhibitors in ARID1A-mutated cells

Nature Communications
2018 | Journal article
DOI: 10.1038/s41467-018-06656-6
EID:

2-s2.0-85054581280
Contributors: Wu, S.; Fatkhutdinov, N.; Fukumoto, T.; Bitler, B.G.; Park, P.H.; Kossenkov, A.V.; Trizzino, M.; Tang, H.-Y.; Zhang, L.; Gardini, A. et al.
Source: Self-asserted source
Shuai Wu via Scopus - Elsevier

The Tumor Suppressor ARID1A Controls Global Transcription via Pausing of RNA Polymerase II

Cell Reports
2018 | Journal article
DOI: 10.1016/j.celrep.2018.05.097
EID:

2-s2.0-85048889208
Contributors: Trizzino, M.; Barbieri, E.; Petracovici, A.; Wu, S.; Welsh, S.A.; Owens, T.A.; Licciulli, S.; Zhang, R.; Gardini, A.
Source: Self-asserted source
Shuai Wu via Scopus - Elsevier

A potent in Vivo antitumor efficacy of novel recombinant type i interferon

Clinical Cancer Research
2017 | Journal article
DOI: 10.1158/1078-0432.CCR-16-1386
EID:

2-s2.0-85018442077
Contributors: Zhang, K.-J.; Yin, X.-F.; Yang, Y.-Q.; Li, H.-L.; Xu, Y.-N.; Chen, L.-Y.; Liu, X.-J.; Yuan, S.-J.; Fang, X.-L.; Xiao, J. et al.
Source: Self-asserted source
Shuai Wu via Scopus - Elsevier

ARID1A-mutated ovarian cancers depend on HDAC6 activity

Nature Cell Biology
2017 | Journal article
DOI: 10.1038/ncb3582
EID:

2-s2.0-85026446470
Contributors: Bitler, B.G.; Wu, S.; Park, P.H.; Hai, Y.; Aird, K.M.; Wang, Y.; Zhai, Y.; Kossenkov, A.V.; Vara-Ailor, A.; Rauscher, F.J. et al.
Source: Self-asserted source
Shuai Wu via Scopus - Elsevier

Harnessing mutual exclusivity between TP53 and ARID1 A mutations

Cell Cycle
2017 | Journal article
DOI: 10.1080/15384101.2017.1377503
EID:

2-s2.0-85039152066
Contributors: Wu, S.; Fatkhutdinov, N.; Zhang, R.
Source: Self-asserted source
Shuai Wu via Scopus - Elsevier

SNORD126 promotes HCC and CRC cell growth by activating the PI3K-AKT pathway through FGFR2

Journal of Molecular Cell Biology
2017 | Journal article
DOI: 10.1093/jmcb/mjw048
EID:

2-s2.0-85021366096
Contributors: Fang, X.; Yang, D.; Luo, H.; Wu, S.; Dong, W.; Xiao, J.; Yuan, S.; Ni, A.; Zhang, K.-J.; Liu, X.-Y. et al.
Source: Self-asserted source
Shuai Wu via Scopus - Elsevier

Arid1a controls tissue regeneration

Stem Cell Investigation
2016 | Journal article
DOI: 10.21037/sci.2016.07.07
EID:

2-s2.0-84994881445
Contributors: Wu, S.; Zhang, R.; Bitler, B.G.
Source: Self-asserted source
Shuai Wu via Scopus - Elsevier

Transmembrane domain is crucial to the subcellular localization and function of Myc target 1

Journal of Cellular and Molecular Medicine
2016 | Journal article
DOI: 10.1111/jcmm.12747
EID:

2-s2.0-84958631737
Contributors: Wu, S.; Gui, J.; Yin, X.; Pan, Q.; Liu, X.; Chu, L.
Source: Self-asserted source
Shuai Wu via Scopus - Elsevier

RGD-modifided oncolytic adenovirus exhibited potent cytotoxic effect on CAR-negative bladder cancer-initiating cells

Cell Death and Disease
2015 | Journal article
DOI: 10.1038/cddis.2015.128
EID:

2-s2.0-84970917194
Contributors: Yang, Y.; Xu, H.; Shen, J.; Yang, Y.; Wu, S.; Xiao, J.; Xu, Y.; Liu, X.-Y.; Chu, L.
Source: Self-asserted source
Shuai Wu via Scopus - Elsevier

Survive or die? c-MYC has the last word

Cell death &amp; disease
2015 | Journal article
DOI: 10.1038/cddis.2015.366
EID:

2-s2.0-85020318200
Contributors: Wu, S.; Yin, X.; Liu, X.; Chu, L.
Source: Self-asserted source
Shuai Wu via Scopus - Elsevier

Lithium down-regulates histone deacetylase 1 (HDAC1) and induces degradation of mutant huntingtin

Journal of Biological Chemistry
2013 | Journal article
DOI: 10.1074/jbc.M113.479865
EID:

2-s2.0-84894355071
Contributors: Wu, S.; Zheng, S.-D.; Huang, H.-L.; Yan, L.-C.; Yin, X.-F.; Xu, H.-N.; Zhang, K.-J.; Gui, J.-H.; Chu, L.; Liu, X.-Y.
Source: Self-asserted source
Shuai Wu via Scopus - Elsevier

A new oncolytic adenoviral vector carrying dual tumour suppressor genes shows potent anti-tumour effect

Journal of Cellular and Molecular Medicine
2012 | Journal article
DOI: 10.1111/j.1582-4934.2011.01396.x
EID:

2-s2.0-84861569599
Contributors: Liu, X.-R.; Cai, Y.; Cao, X.; Wei, R.-C.; Li, H.-L.; Zhou, X.-M.; Zhang, K.-J.; Wu, S.; Qian, Q.-J.; Cheng, B. et al.
Source: Self-asserted source
Shuai Wu via Scopus - Elsevier

Peer review (24 reviews for 2 publications/grants)

Review activity for Biochemical genetics. (1)
Review activity for Cancer cell international. (23)
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