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Works (31)

DNA G-Quadruplexes as Targets for Natural Product Drug Discovery

Engineering
2024-07 | Journal article
DOI: 10.1016/j.eng.2024.03.015
Contributors: Kai-Bo Wang; Yingying Wang; Jonathan Dickerhoff; Danzhou Yang
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Design, Synthesis, and Investigation of the Pharmacokinetics and Anticancer Activities of Indenoisoquinoline Derivatives That Stabilize the G-Quadruplex in the MYC Promoter and Inhibit Topoisomerase I

Journal of Medicinal Chemistry
2024-05-09 | Journal article
DOI: 10.1021/acs.jmedchem.3c02303
Contributors: Yichen Han; Adam Buric; Venkat Chintareddy; Mercedes DeMoss; Luying Chen; Jonathan Dickerhoff; Robyn De Dios; Pooran Chand; Randall Riggs; Danzhou Yang et al.
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Negative Electron Transfer Collision-Induced Dissociation of G-Quadruplexes: Uncovering the Guanine Radical Anion Loss Pathway

Journal of the American Society for Mass Spectrometry
2024-04-03 | Journal article
DOI: 10.1021/jasms.3c00443
Contributors: Nicole M. Brundridge; Jordan M. Fritz; Jonathan Dickerhoff; Danzhou Yang; Scott A. McLuckey
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Gas-Phase Fragmentation as a Probe of G-Quadruplex Formation

Analytical Chemistry
2023-10-10 | Journal article
DOI: 10.1021/acs.analchem.3c03143
Contributors: Nicole M. Brundridge; Jonathan Dickerhoff; Danzhou Yang; Scott A. McLuckey
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DNA G-Quadruplex in Human Telomeres and Oncogene Promoters: Structures, Functions, and Small Molecule Targeting

Accounts of Chemical Research
2022-09-20 | Journal article
DOI: 10.1021/acs.accounts.2c00337
Contributors: Luying Chen; Jonathan Dickerhoff; Saburo Sakai; Danzhou Yang
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Oxidative Damage Induces a Vacancy G-Quadruplex That Binds Guanine Metabolites: Solution Structure of a cGMP Fill-in Vacancy G-Quadruplex in the Oxidized BLM Gene Promoter

Journal of the American Chemical Society
2022-04-13 | Journal article
DOI: 10.1021/jacs.2c00435
Contributors: Kai-Bo Wang; Yushuang Liu; Yipu Li; Jonathan Dickerhoff; Jinzhu Li; Ming-Hua Yang; Danzhou Yang; Ling-Yi Kong
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Crossref

Berberine Molecular Recognition of the Parallel MYC G-Quadruplex in Solution

Journal of Medicinal Chemistry
2021-11-11 | Journal article
DOI: 10.1021/acs.jmedchem.1c01508
Contributors: Jonathan Dickerhoff; Nicole Brundridge; Scott A. McLuckey; Danzhou Yang
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Solution Structure of Ternary Complex of Berberine Bound to a dGMP–Fill-In Vacancy G-Quadruplex Formed in the PDGFR-β Promoter

Journal of the American Chemical Society
2021-10-13 | Journal article
DOI: 10.1021/jacs.1c06200
Contributors: Kai-Bo Wang; Jonathan Dickerhoff; Danzhou Yang
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Evaluating Molecular Docking Software for Small Molecule Binding to G-Quadruplex DNA

International Journal of Molecular Sciences
2021-10-06 | Journal article
DOI: 10.3390/ijms221910801
Contributors: Jonathan Dickerhoff; Kassandra R. Warnecke; Kaibo Wang; Nanjie Deng; Danzhou Yang
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Novel DNA Bis-Intercalator XR5944 as a Potent Anticancer Drug—Design and Mechanism of Action

Molecules
2021-07-07 | Journal article
DOI: 10.3390/molecules26144132
Contributors: Adam J. Buric; Jonathan Dickerhoff; Danzhou Yang
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Structural recognition of the MYC promoter G-quadruplex by a quinoline derivative: insights into molecular targeting of parallel G-quadruplexes.

Nucleic acids research
2021-05-12 | Journal article
DOI: 10.1093/nar/gkab330
PMID: 33978746
Source: Self-asserted source
Jonathan Dickerhoff

PDGFR-β Promoter Forms a Vacancy G-Quadruplex that Can Be Filled in by dGMP: Solution Structure and Molecular Recognition of Guanine Metabolites and Drugs

Journal of the American Chemical Society
2020-03-18 | Journal article
DOI: 10.1021/jacs.9b12770
Contributors: Kai-Bo Wang; Jonathan Dickerhoff; Guanhui Wu; Danzhou Yang
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Sugar Puckering Drives G‐Quadruplex Refolding: Implications for V‐Shaped Loops

Chemistry – A European Journal
2020-01-07 | Journal article
DOI: 10.1002/chem.201904044
Contributors: Linn Haase; Jonathan Dickerhoff; Klaus Weisz
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Solution Structure of a MYC Promoter G-Quadruplex with 1:6:1 Loop Length

ACS Omega
2019-02-28 | Journal article
DOI: 10.1021/acsomega.8b03580
Contributors: Jonathan Dickerhoff; Buket Onel; Luying Chen; Yuwei Chen; Danzhou Yang
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DNA–RNA Hybrid Quadruplexes Reveal Interactions that Favor RNA Parallel Topologies

Chemistry – A European Journal
2018-10-12 | Journal article
DOI: 10.1002/chem.201803367
Contributors: Linn Haase; Jonathan Dickerhoff; Klaus Weisz
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Crossref

Fluorine‐Mediated Editing of a G‐Quadruplex Folding Pathway

ChemBioChem
2018-05-04 | Journal article
DOI: 10.1002/cbic.201800099
Contributors: Jonathan Dickerhoff; Klaus Weisz
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Crossref

Ligand‐Induced Dimerization of a Truncated Parallel MYC G‐Quadruplex

ChemBioChem
2018-03-02 | Journal article
DOI: 10.1002/cbic.201700593
Contributors: Andrea Funke; Beatrice Karg; Jonathan Dickerhoff; Darko Balke; Sabine Müller; Klaus Weisz
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Nonconventional C–H···F Hydrogen Bonds Support a Tetrad Flip in Modified G-Quadruplexes

The Journal of Physical Chemistry Letters
2017-10-19 | Journal article
DOI: 10.1021/acs.jpclett.7b02428
Contributors: Jonathan Dickerhoff; Klaus Weisz
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Crossref

Selective Targeting of G-Quadruplex Structures by a Benzothiazole-Based Binding Motif.

2017-03 | Journal article
DOI: 10.1002/chem.201700298
PMID: 28276093
Contributors: Buchholz I; Karg B; Dickerhoff J; Sievers-Engler A; Lämmerhofer M; Weisz K
Source: Self-asserted source
Jonathan Dickerhoff via Europe PubMed Central
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Tracing Effects of Fluorine Substitutions on G-Quadruplex Conformational Changes.

2017-03 | Journal article
DOI: 10.1021/acschembio.6b01096
PMID: 28318229
Contributors: Dickerhoff J; Haase L; Langel W; Weisz K
Source: Self-asserted source
Jonathan Dickerhoff via Europe PubMed Central

Observation of a Dynamic G-Tetrad Flip in Intramolecular G-Quadruplexes

Biochemistry
2016-11 | Journal article
DOI: 10.1021/acs.biochem.6b00925
Contributors: Beatrice Karg; Linn Haase; Andrea Funke; Jonathan Dickerhoff; Klaus Weisz
Source: Self-asserted source
Jonathan Dickerhoff via Crossref Metadata Search

Sugar-Edge Interactions in a DNA-RNA G-Quadruplex: Evidence of Sequential C-H⋅⋅⋅O Hydrogen Bonds Contributing to RNA Quadruplex Folding.

2016-11 | Journal article
DOI: 10.1002/anie.201608275
PMID: 27860177
Contributors: Dickerhoff J; Appel B; Müller S; Weisz K
Source: Self-asserted source
Jonathan Dickerhoff via Europe PubMed Central

Zuckerseitige Wechselwirkungen in einem DNA-RNA-G-Quadruplex: Hinweise auf sequentielle C−H⋅⋅⋅O-Wasserstoffbrücken als Beitrag zur RNA-Quadruplex-Faltung

Angewandte Chemie
2016-11-07 | Journal article
DOI: 10.1002/ange.201608275
Contributors: Jonathan Dickerhoff; Bettina Appel; Sabine Müller; Klaus Weisz
Source: Self-asserted source
Jonathan Dickerhoff via Crossref Metadata Search

Towards the Development of Structure-Selective G-Quadruplex-Binding Indolo[3,2-b]quinolines

Chemistry - A European Journal
2016-01 | Journal article
DOI: 10.1002/chem.201504416
Contributors: Andrea Funke; Jonathan Dickerhoff; Klaus Weisz
Source: Self-asserted source
Jonathan Dickerhoff via Crossref Metadata Search
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Exploration of the Substrate Promiscuity of Biosynthetic Tailoring Enzymes as a New Source of Structural Diversity for Polyene Macrolide Antifungals

ChemCatChem
2015 | Journal article
DOI: https://doi.org/10.1002/cctc.201402773
Source: Self-asserted source
Jonathan Dickerhoff

Selective Access to All Four Diastereomers of a 1,3-Amino Alcohol by Combination of a Keto Reductase- and an Amine Transaminase-Catalysed Reaction

Advanced Synthesis & Catalysis
2015 | Journal article
DOI: https://doi.org/10.1002/adsc.201500214
Source: Self-asserted source
Jonathan Dickerhoff

Two subtle amino Acid changes in a transaminase substantially enhance or invert enantiopreference in cascade syntheses.

2015-05 | Journal article
DOI: 10.1002/cbic.201500074
PMID: 25801772
Contributors: Skalden L; Peters C; Dickerhoff J; Nobili A; Joosten HJ; Weisz K; Höhne M; Bornscheuer UT
Source: Self-asserted source
Jonathan Dickerhoff via Europe PubMed Central

Structure and catalytic mechanism of the evolutionarily unique bacterial chalcone isomerase.

2015-04 | Journal article
DOI: 10.1107/s1399004715001935
PMID: 25849401
Contributors: Thomsen M; Tuukkanen A; Dickerhoff J; Palm GJ; Kratzat H; Svergun DI; Weisz K; Bornscheuer UT; Hinrichs W
Source: Self-asserted source
Jonathan Dickerhoff via Europe PubMed Central

Flipping a G-Tetrad in a Unimolecular Quadruplex Without Affecting Its Global Fold

Angewandte Chemie International Edition
2015-03 | Journal article
DOI: 10.1002/anie.201411887
Contributors: Jonathan Dickerhoff; Klaus Weisz
Source: Self-asserted source
Jonathan Dickerhoff via Crossref Metadata Search

Flipping a G-Tetrad in a Unimolecular Quadruplex Without Affecting Its Global Fold

Angewandte Chemie
2015-03 | Journal article
DOI: 10.1002/ange.201411887
Contributors: Jonathan Dickerhoff; Klaus Weisz
Source: Self-asserted source
Jonathan Dickerhoff via Crossref Metadata Search

Exploring multiple binding sites of an indoloquinoline in triple-helical DNA: A paradigm for DNA triplex-selective intercalators

Biochimie
2014 | Journal article
DOI: 10.1016/j.biochi.2014.09.022
Contributors: Jonathan Dickerhoff; Fanny Riechert-Krause; Jenny Seifert; Klaus Weisz
Source: Self-asserted source
Jonathan Dickerhoff via Crossref Metadata Search
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