Joel E. López-Meza (0000-0002-3269-9202)

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Behind anticancer molecules: lactoferricin dimeric peptides with fast, selective, persistent and broad-spectrum cytotoxic effect

Exploration of Drug Science

2025-02-26 | Journal article

DOI: 10.37349/eds.2025.100891

Contributors: Karen Johanna Cárdenas-Martínez; Juan Esteban Reyes-Calderon; Claudia Marcela Parra-Giraldo; Yerly Vargas-Casanova; Andrea Carolina Barragán-Cárdenas; Ricardo Fierro-Medina; Joel E. Lopez-Meza; Luis Fernando Ospina-Giraldo; Zuly Jenny Rivera-Monroy; Javier Eduardo García-Castañeda

Joel E. López-Meza

https://orcid.org/0000-0002-3269-9202

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Works (50 of 98)

Behind anticancer molecules: lactoferricin dimeric peptides with fast, selective, persistent and broad-spectrum cytotoxic effect

Antioxidant and Antifungal Activities and Characterization of Phenolic Compounds Using Ultra-High Performance Liquid Chromatography and Mass Spectrometry (UPLC-MS) of Aqueous Extracts and Fractions from Verbesina sphaerocephala Stems

The GPR30 Receptor Is Involved in IL-6-Induced Metastatic Properties of MCF-7 Luminal Breast Cancer Cells

The GPR30 Receptor is Involved in IL-6-Induced Metastatic Properties in MCF-7 Luminal Breast Cancer Cells

Enhanced breast cancer cell targeting: RGD integrin ligand potentiates RWQWRWQWR’s cytotoxicity and inhibits migration

Facile synthesis of gold nanoflowers and their application in glycerol electro-oxidation

GPER: An Estrogen Receptor Key in Metastasis and Tumoral Microenvironments

The plant defensins PaDef and γ-thionin inhibit the endothelial cell response to VEGF

The Antimicrobial Peptide γ-Thionin from Habanero Chile (Capsicum chinense) Induces Caspase-Independent Apoptosis on Human K562 Chronic Myeloid Leukemia Cells and Regulates Epigenetic Marks

Changes in Length and Positive Charge of Palindromic Sequence RWQWRWQWR Enhance Cytotoxic Activity against Breast Cancer Cell Lines

Antifungal Activity of Avocado Seed Recombinant GASA/Snakin PaSn

Prolactin regulates H3K9ac and H3K9me2 epigenetic marks and miRNAs expression in bovine mammary epithelial cells challenged with Staphylococcus aureus

LfcinB-Derived Peptides: Specific and punctual change of an amino acid in monomeric and dimeric sequences increase selective cytotoxicity in colon cancer cell lines

Biological Activities of Organic Extracts of the Genus Aristolochia: A Review from 2005 to 2021

PaDef (Persea americana var. drymifolia), a Plant Antimicrobial Peptide, Triggers Apoptosis, and Induces Global Epigenetic Modifications on Histone 3 in an Acute Lymphoid Leukemia Cell Line

In vitro cytotoxic potential of extracts from Aristolochia foetida Kunth against MCF-7 and bMECs cell lines

Defensin γ-thionin from Capsicum chinense improves butyrate cytotoxicity on human colon adenocarcinoma cell line Caco-2

Cytotoxicity of a Lipid-Rich Extract from Native Mexican Avocado Seed (Persea americana var. drymifolia) on Canine Osteosarcoma D-17 Cells and Synergistic Activity with Cytostatic Drugs

Bioactive Molecules From Native Mexican Avocado Fruit (Persea americana var. drymifolia): A Review

Two Oleosins Expressed in the Mesocarp of Native Mexican Avocado, Key Genes in the Oil Content

Analysis of virulence traits of Staphylococcus aureus isolated from bovine mastitis in semi-intensive and family dairy farms

Lipid-rich extract from Mexican avocado (Persea americana var. drymifolia) induces apoptosis and modulates the inflammatory response in Caco-2 human colon cancer cells

Plant Defensin γ-Thionin Induces MAPKs and Activates Histone Deacetylases in Bovine Mammary Epithelial Cells Infected With Staphylococcus aureus

Production and characterization of a monoclonal antibody against the sialidase of Gardnerella vaginalis using a synthetic peptide in a MAP8 format

Pyrolytic oils from Amphipterygium adstringens bark inhibit IL-8 production of IL-17-stimulated HaCaT keratinocytes

The Nonapeptide RWQWRWQWR: A Promising Molecule for Breast Cancer Therapy

Prolactin and Estradiol are Epigenetic Modulators in Bovine Mammary Epithelial Cells during Staphylococcus aureus Infection

Peptides Derived from (RRWQWRMKKLG)2-K-Ahx Induce Selective Cellular Death in Breast Cancer Cell Lines through Apoptotic Pathway

Molecular characterization of bacterial microbiota associated with infectious bovine keratoconjunctivitis in Michoacán, Mexico

Immunomodulatory molecules regulate adhesin gene expression in Staphylococcus aureus: Effect on bacterial internalization into bovine mammary epithelial cells

In vitro and in vivo anti-fungal effect of chitosan on post-harvest strawberry pathogens,Efecto antifúngico in vitro e in vivo de quitosano sobre patógenos de fresa en postcosecha

The tetrameric peptide LfcinB (20–25)4 derived from bovine lactoferricin induces apoptosis in the MCF-7 breast cancer cell line

Lipid-Rich Extract from Mexican Avocado Seed (Persea americana var. drymifolia) Reduces Staphylococcus aureus Internalization and Regulates Innate Immune Response in Bovine Mammary Epithelial Cells

Antimicrobial activity of broccoli (Brassica oleracea var. italica) cultivar Avenger against pathogenic bacteria, phytopathogenic filamentous fungi and yeast

Immunomodulatory effects of thionin Thi2.1 from Arabidopsis thaliana on bovine mammary epithelial cells

PaDef defensin from avocado (Persea americana var. drymifolia) is cytotoxic to K562 chronic myeloid leukemia cells through extrinsic apoptosis

Immunomodulatory Effects of 17β-Estradiol on Epithelial Cells during Bacterial Infections

Antioxidant activity of the essential oil and its major terpenes of Satureja macrostema (Moc. and Sessé ex Benth.) Briq.

Arabidopsis thaliana sucrose phosphate synthase (sps) genes are expressed differentially in organs and tissues, and their transcription is regulated by osmotic stress

Expression analysis of the Arabidopsis thaliana AtSpen2 gene, and its relationship with other plant genes encoding spen proteins

Sodium octanoate modulates the innate immune response of bovine mammary epithelial cells through the TLR2/P38/JNK/ERK1/2 pathway: Implications during Staphylococcus aureus internalization

A new allele of γ-kafirin gene coding for a protein with high lysine content in Mexican white sorghum germplasm

Anti-inflammatory and antimicrobial effects of estradiol in bovine mammary epithelial cells during staphylococcus aureus internalization

Defensin γ-thionin from Capsicum chinense has immunomodulatory effects on bovine mammary epithelial cells during Staphylococcus aureus internalization

The defensin from avocado (Persea americana var. drymifolia) PaDef induces apoptosis in the human breast cancer cell line MCF-7

Transcriptome (ESTs) of native Mexican avocado fruit is dominated by stress and innate immunity genes

A plasmid-encoded UmuD homologue regulates expression of pseudomonas aeruginosa SOS genes

Antimicrobial Peptides: Current and Potential Applications in Biomedical Therapies

Non-classical effects of prolactin on the innate immune response of bovine mammary epithelial cells: Implications during Staphylococcus aureus internalization

Plant Antimicrobial Peptides as Potential Anticancer Agents

Peer review (8 reviews for 3 publications/grants)