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ResearcherID: H-1977-2013
Scopus Author ID: 57191897719
Scopus Author ID: 57203943387

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Australia

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Employment (3)

School of Biomedical Sciences, University of Queensland: Brisbane, Queensland, AU

2016-10 to present | Postdoctoral research fellow
Employment
Source: Self-asserted source
Lei Qian

Queensland Brain Institute, University of Queensland: Brisbane, QLD, AU

2013-07 to present | Postdoctoral Research Fellow
Employment
Source: Self-asserted source
Lei Qian

GlaxoSmithKline Research and Development China: Shanghai, Shanghai, CN

2007-12 to 2013-06 | Scientist (Neurodegeneration Discovery Performance Unit)
Employment
Source: Self-asserted source
Lei Qian

Education and qualifications (1)

Institute of Neuroscience Chinese Academy of Sciences: Shanghai, Shanghai, CN

2004-09 to 2008-03 | Ph. D. in Neurobiology
Education
Source: Self-asserted source
Lei Qian

Works (12)

Somatostatin neurons in the central amygdala mediate anxiety by disinhibition of the central sublenticular extended amygdala

Molecular Psychiatry
2023-10 | Journal article
DOI: 10.1038/s41380-020-00894-1
Contributors: Yajie Sun; Lei Qian; Li Xu; Sarah Hunt; Pankaj Sah
Source: check_circle
Crossref
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Cholinergic basal forebrain degeneration due to sleep-disordered breathing exacerbates pathology in a mouse model of Alzheimer’s disease

Nature Communications
2022-11-02 | Journal article
DOI: 10.1038/s41467-022-33624-y
Contributors: Lei Qian; Oliver Rawashdeh; Leda Kasas; Michael R. Milne; Nicholas Garner; Kornraviya Sankorrakul; Nicola Marks; Matthew W. Dean; Pu Reum Kim; Aanchal Sharma et al.
Source: check_circle
Crossref

Is there a role for the p75 neurotrophin receptor in mediating degeneration during oxidative stress and after hypoxia?

Journal of Neurochemistry
2021-09 | Journal article
DOI: 10.1111/jnc.15451
Contributors: Kornraviya Sankorrakul; Lei Qian; Wipawan Thangnipon; Elizabeth J. Coulson
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Crossref
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Cholinergic basal forebrain degeneration due to obstructive sleep apnoea increases Alzheimer's pathology in mice

bioRxiv
2020 | Other
DOI: 10.1101/2020.03.12.989848
EID:

2-s2.0-85102722358

Part of ISSN: 26928205
Contributors: Qian, L.; Kasas, L.; Milne, M.R.; Rawashdeh, O.; Marks, N.; Sharma, A.; Bellingham, M.C.; Coulson, E.J.
Source: Self-asserted source
Lei Qian via Scopus - Elsevier

p110δ PI 3-kinase inhibition perturbs APP and TNFα trafficking, reduces plaque burden, dampens neuroinflammation and prevents cognitive decline in an Alzheimer's disease mouse model.

The Journal of Neuroscience
2019-07-30 | Journal article
DOI: 10.1523/jneurosci.0674-19.2019
PMID: 31363064
Source: Self-asserted source
Lei Qian
grade
Preferred source (of 3)‎

Downregulation of SNX27 expression does not exacerbate amyloidogenesis in the APP/PS1 Alzheimer's disease mouse model.

Neurobiology of aging
2019-01-25 | Journal article
DOI: 10.1016/j.neurobiolaging.2019.01.011
PMID: 30797171
Source: Self-asserted source
Lei Qian
grade
Preferred source (of 2)‎

Removal of p75 Neurotrophin Receptor Expression from Cholinergic Basal Forebrain Neurons Reduces Amyloid-β Plaque Deposition and Cognitive Impairment in Aged APP/PS1 Mice.

Molecular neurobiology
2018-10-29 | Journal article
DOI: 10.1007/s12035-018-1404-2
PMID: 30374941
Source: Self-asserted source
Lei Qian
grade
Preferred source (of 2)‎

Cholinergic basal forebrain neurons regulate fear extinction consolidation through p75 neurotrophin receptor signaling

Translational Psychiatry
2018-09-21 | Journal article
DOI: 10.1038/s41398-018-0248-x
Contributors: Zoran Boskovic; Michael R. Milne; Lei Qian; Hamish D. Clifton; Alice E. McGovern; Marion T. Turnbull; Stuart B. Mazzone; Elizabeth J. Coulson
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Crossref
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Sirt1 Overexpression in Neurons Promotes Neurite Outgrowth and Cell Survival Through Inhibition of the mTOR Signaling

Journal of Neuroscience Research
2011 | Journal article
DOI:

10.1002/jnr.22725

Part of ISSN:

0360-4012
Contributors: Chen, Tongsheng; Guo, Wenjing; Hayes, Philip; Morrison, Alastair; Qian, Lei; Wilson, Steve; Zhang, Jing; Zhang, Wei; Zhao, Jie
Source: Self-asserted source
Lei Qian via ResearcherID
grade
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Wnt/beta-catenin signaling suppresses Rapsyn expression and inhibits acetylcholine receptor clustering at the neuromuscular junction

Journal of Biological Chemistry
2008 | Journal article
DOI:

10.1074/jbc.M709939200

Part of ISSN:

0021-9258
Contributors: Chen, Fei; Lei, Wen-Liang; Luo, Zhen-Ge; Qian, Lei; Ruan, Nan-Jie; Wang, Jia
Source: Self-asserted source
Lei Qian via ResearcherID
grade
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Dishevelled promotes axon differentiation by regulating atypical protein kinase C

Nature Cell Biology
2007 | Journal article
DOI:

10.1038/ncb1603

Part of ISSN:

1465-7392
Contributors: Chen, Fei; Chen, Yan-Min; Hu, Han-Song; Luo, Zhen-Ge; Qian, Lei; Tao, Yu; Wang, Qing-Jie; Wang, Tong; Yang, Guo-Ying; Zhang, Xian et al.
Source: Self-asserted source
Lei Qian via ResearcherID
grade
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Rapsyn interaction with calpain stabilizes AChR clusters at the neuromuscular junction

Neuron
2007 | Journal article
DOI:

10.1016/j.neuron.2007.06.031

Part of ISSN:

0896-6273
Contributors: Chen, Fei; Ding, Yu-Qiang; Huang, Ying; Luo, Zhen-Ge; Mei, Lin; Ngo, Shyuan T.; Noakes, Peter G.; Qian, Lei; Ruan, Nan-Jie; Schneider, Claudio et al.
Source: Self-asserted source
Lei Qian via ResearcherID
grade
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Peer review (1 review for 1 publication/grant)

Review activity for Molecular brain (1)
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