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Infectious Diseases, Communicable Diseases, Enteric Diseases, Public health microbiology
South Africa

Biography

This personal statement was updated on 26 January 2024. I am currently employed as a Principal Medical Scientist at the Centre for Enteric Diseases (CED), National Institute for Communicable Diseases (NICD), in Johannesburg, South Africa. I have a 34-year employment history with this institution. I obtained my PhD in molecular microbiology from the University of the Witwatersrand in May 1996. I hold joint staff appointments with University of Pretoria (Extraordinary Professor) and University of the Witwatersrand (Senior Research Officer). I have a 'B2' rating with the National Research Foundation (NRF) of South Africa; a rating category for 'researchers who enjoy considerable international recognition by their peers for the high quality and impact of their recent research outputs'. The CED is a reference centre in South Africa for human isolates of Salmonella species, Shigella species, Vibrio cholerae, Listeria monocytogenes and diarrhoeagenic Escherichia coli. I am a steering committee member of PulseNet International - PulseNet is a molecular subtyping network for global enteric disease surveillance. My current activities include diagnosis, surveillance and epidemiology of enteric bacterial pathogens in South Africa. I lecture and teach on the application of molecular techniques in the microbiology laboratory, including techniques related to laboratory identification and characterization of bacterial enteric pathogens. These techniques include PCR, whole-genome sequencing and metagenomics. I am also involved with supervision of post-graduate students and training of intern medical scientists. My supervision of post-graduate students includes 8 PhD students and 17 MSc students. Most of my published work is listed at: https://www.ncbi.nlm.nih.gov/myncbi/1vGRCoG6Yfq/bibliography/public/

Activities

Employment (1)

National Institute for Communicable Diseases: Johannesburg, ZA

1990-01-02 to present
Employment
Source: Self-asserted source
Anthony Smith

Education and qualifications (1)

University of the Witwatersrand: Johannesburg-Braamfontein, Gauteng, ZA

1986-01-02 to present
Education
Source: Self-asserted source
Anthony Smith

Works (19)

Expediting pathogen genomics adoption for enhanced foodborne disease surveillance in Africa

eBioMedicine
2025-01 | Journal article
Contributors: Aquillah M. Kanzi; Stella I. Smith; Chisomo Msefula; John Mwaba; Abraham Ajayi; Geoffrey Kwenda; Collins K. Tanui; Anthony M. Smith; Linda A. Bester; Firehiwot A. Derra et al.
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Detection of the epidemic Pseudomonas aeruginosa AUST‐03 (ST242) strain in people with cystic fibrosis in South Africa

Pediatric Pulmonology
2024-12 | Journal article
Contributors: Thabo Hamiwe; Debbie A. White; Stanford Kwenda; Arshad Ismail; Susan Klugman; Lore Van Bruwaene; Ameena Goga; Marleen M. Kock; Anthony M. Smith; Marthie M. Ehlers
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Genomics sequence data of a drug-resistant Pseudomonas aeruginosa producing Tripoli Metallo-β-lactamase 1 isolated from Sudan

Data in Brief
2024-12 | Journal article
Contributors: Sara E. Mohammed; Omnia Hamid; Mohammed Abdelrahim; Arshad Ismail; Anthony M. Smith; Mushal Allam
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Whole genome sequencing assisted outbreak investigation of Salmonella enteritidis, at a hospital in South Africa, September 2022

Access Microbiology
2024-12-01 | Journal article
Contributors: Brian Brümmer; Anthony Marius Smith; Motshabi Modise; Juno Thomas; Hetani Mdose; Ramasedi Mokoena; Dikeledi Baleni
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Whole-Genome Sequencing assisted outbreak investigation of Salmonella Enteritidis, at a hospital in South Africa, September 2022

2024-10-04 | Preprint
Contributors: Brian Brummer; Anthony Marius Smith; Motshabi Modise; Juno Thomas; Hetani Mdose; Ramasedi Mokoena; Dikeledi Baleni
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Metagenomics analysis of sewage for surveillance of antimicrobial resistance in South Africa

PLOS ONE
2024-08-26 | Journal article
Contributors: Anthony M. Smith; Mabel Kamweli Aworh; Masindi Ramudzulu; Patrick Munk; Baptiste J. P. Avot; Kerneels C. M. Esterhuyse; Nico van Blerk; Stanford Kwenda; Phuti Sekwadi
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Whole-Genome Sequencing of Human and Porcine Escherichia coli Isolates on a Commercial Pig Farm in South Africa

Antibiotics
2024-06-11 | Journal article
Contributors: Wilhelmina Strasheim; Michelle Lowe; Anthony M. Smith; Eric M. C. Etter; Olga Perovic
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Preferred source (of 2)‎

Whole Genome Sequencing of Human and Porcine <em>Escherichia coli </em>Isolates on a Commercial Pig Farm in South Africa

2024-05-15 | Preprint
Contributors: Wilhelmina Strasheim; Michelle Lowe; Anthony M Smith; Eric MC Etter; Olga Perovic
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Preferred source (of 2)‎

Whole-Genome Sequencing assisted outbreak investigation of Salmonella Enteritidis, at a hospital in South Africa, September 2022

2024-05-01 | Preprint
Contributors: Brian Brummer; Anthony Marius Smith; Motshabi Modise; Juno Thomas; Hetani Mdose; Ramasedi Mokoena; Dikeledi Baleni
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Crossref

Antimicrobial susceptibility profile ofNeisseria gonorrhoeaefrom patients attending a medical laboratory, Institut Pasteur de Madagascar between 2014 and 2020: phenotypical and genomic characterisation in a subset ofNeisseria gonorrhoeaeisolates

Sexually Transmitted Infections
2024-02 | Journal article
Contributors: Lala Fanomezantsoa Rafetrarivony; Mamitina Alain Noah Rabenandrasana; Elisoa Ratsima Hariniaina; Frédérique Randrianirina; Anthony Marius Smith; Tania Crucitti
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The genomic epidemiology of shigellosis in South Africa

Nature Communications
2023-11-24 | Journal article
Contributors: George E. Stenhouse; Karen H. Keddy; Rebecca J. Bengtsson; Neil Hall; Anthony M. Smith; Juno Thomas; Miren Iturriza-Gómara; Kate S. Baker
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Report of epidemic Pseudomonas aeruginosa AUST-03 (ST 242) strains and resistomes in South African cystic fibrosis patients

2023-10-23 | Preprint
Contributors: Thabo Hamiwe; Debbie White; Stanford Kwenda; Arshad Ismail; Susan Klugman; Lore Van Bruwaene; Ameena Goga; Marleen M. Kock; Anthony Smith; Marthie M. Ehlers
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Enteric fever cluster identification in South Africa using genomic surveillance of Salmonella enterica serovar Typhi

Microbial Genomics
2023-06-20 | Journal article
Contributors: Anthony Marius Smith; Linda Kathleen Erasmus; Nomsa Pauline Tau; Shannon Lucrecia Smouse; Hlengiwe Mimmy Ngomane; Bolele Disenyeng; Andrew Whitelaw; Charlene Ann Lawrence; Phuti Sekwadi; Juno Thomas
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Unlocking the Potential of Genomic Data to Inform Typhoid Fever Control Policy: Supportive Resources for Genomic Data Generation, Analysis, and Visualization

Open Forum Infectious Diseases
2023-06-02 | Journal article
Contributors: Megan E Carey; Zoe A Dyson; Silvia Argimón; Louise Cerdeira; Corin Yeats; David Aanensen; Gerald Mboowa; Stephen Baker; Sofonias K Tessema; Anthony M Smith et al.
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The genomic epidemiology of shigellosis in South Africa

2023-05-26 | Preprint
Contributors: George Stenhouse; Karen Keddy; Rebecca Bengtsson; Neil Hall; Anthony Smith; Juno Thomas; Mirren Iturriza-Gómara; Kate Baker
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Antimicrobial susceptibility and genomic profiling of Salmonella enterica from bloodstream infections at a tertiary referral hospital in Lusaka, Zambia, 2018–2019

IJID Regions
2022-06 | Journal article
Contributors: Kaunda Yamba; Christine Kapesa; Evans Mpabalwani; Lottie Hachaambwa; Anthony Marius Smith; Andrea Liezl Young; David Gally; Geoffrey Mainda; Mercy Mukuma; Mulemba Tillika Samutela et al.
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Whole-genome sequencing to investigate two concurrent outbreaks of Salmonella Enteritidis in South Africa, 2018

Journal of Medical Microbiology
2020-11-01 | Journal article
Contributors: Anthony M. Smith; Nomsa P. Tau; Hlengiwe M. Ngomane; Phuti Sekwadi; Ntsieni Ramalwa; Krishnee Moodley; Chetna Govind; Shameema Khan; Moherndran Archary; Juno Thomas
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Shiga toxin-producing Escherichia coli O26:H11 associated with a cluster of haemolytic uraemic syndrome cases in South Africa, 2017

Access Microbiology
2019-11-01 | Journal article
Contributors: Anthony M. Smith; Nomsa P. Tau; Bosco J. Kalule; Mark P. Nicol; Mignon McCulloch; Charlene A. Jacobs; Kerrigan M. McCarthy; Arshad Ismail; Mushal Allam; Jackie Kleynhans
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Virulence Characteristics and Antimicrobial Resistance Profiles of Shiga Toxin-Producing Escherichia coli Isolates from Humans in South Africa: 2006–2013

Toxins
2019-07-19 | Journal article
Contributors: Musafiri Karama; Beniamino T. Cenci-Goga; Mogaugedi Malahlela; Anthony M. Smith; Karen H. Keddy; Saeed El-Ashram; Lawan M. Kabiru; Alan Kalake
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Peer review (2 reviews for 2 publications/grants)

Review activity for Diagnostic microbiology and infectious disease. (1)
Review activity for PLOS global public health. (1)