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University of Pittsburgh: Pittsburgh, PA, US

2015-01-05 to present | Profesor (Computational and Systems Biology)
Employment
Source: Self-asserted source
Jianhua Xing

Works (50 of 62)

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Page 1 of 2

Long-range genomic loci stochastically assemble into combinatorial forms of chromosome skeleton

2025-02-10 | Preprint
Contributors: Jingyu Zhang; Siyuan Wang; Simon C Watkins; Jianhua Xing
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Crossref

GraphVelo allows for accurate inference of multimodal omics velocities and molecular mechanisms for single cells

2025-01-15 | Preprint
Contributors: Jianhua Xing; Yuhao Chen; Yan Zhang; Jiaqi Gan; Ke Ni; Ming Chen; Ivet Bahar
Source: check_circle
Crossref

GraphVelo allows for accurate inference of multimodal velocities and molecular mechanisms for single cells

2024-12-07 | Preprint
Contributors: Yuhao Chen; Yan Zhang; Jiaqi Gan; Ke Ni; Ming Chen; Ivet Bahar; Jianhua Xing
Source: check_circle
Crossref

Transiently Increased Coordination in Gene Regulation During Cell Phenotypic Transitions

PRX Life
2024-11-05 | Journal article
Contributors: Weikang Wang; Ke Ni; Dante Poe; Jianhua Xing
Source: check_circle
Crossref

Data‐ and theory‐driven approaches for understanding paths of epithelial–mesenchymal transition

genesis
2024-04 | Journal article
Contributors: Tian Hong; Jianhua Xing
Source: check_circle
Crossref

Mosaic-PICASSO: accurate crosstalk removal for multiplex fluorescence imaging

Bioinformatics
2024-01-02 | Journal article
Contributors: Hu Cang; Yang Liu; Jianhua Xing; Hanchuan Peng
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Crossref

Data from Targeting the Temporal Dynamics of Hypoxia-Induced Tumor-Secreted Factors Halts Tumor Migration

2023-03-31 | Preprint
Contributors: Manjulata Singh; Xiao-Jun Tian; Vera S. Donnenberg; Alan M. Watson; JingYu Zhang; Laura P. Stabile; Simon C. Watkins; Jianhua Xing; Shilpa Sant
Source: check_circle
Crossref

Data from Targeting the Temporal Dynamics of Hypoxia-Induced Tumor-Secreted Factors Halts Tumor Migration

2023-03-31 | Preprint
Contributors: Manjulata Singh; Xiao-Jun Tian; Vera S. Donnenberg; Alan M. Watson; JingYu Zhang; Laura P. Stabile; Simon C. Watkins; Jianhua Xing; Shilpa Sant
Source: check_circle
Crossref

Supplementary Data from Targeting the Temporal Dynamics of Hypoxia-Induced Tumor-Secreted Factors Halts Tumor Migration

2023-03-31 | Preprint
Contributors: Manjulata Singh; Xiao-Jun Tian; Vera S. Donnenberg; Alan M. Watson; JingYu Zhang; Laura P. Stabile; Simon C. Watkins; Jianhua Xing; Shilpa Sant
Source: check_circle
Crossref

Supplementary Data from Targeting the Temporal Dynamics of Hypoxia-Induced Tumor-Secreted Factors Halts Tumor Migration

2023-03-31 | Preprint
Contributors: Manjulata Singh; Xiao-Jun Tian; Vera S. Donnenberg; Alan M. Watson; JingYu Zhang; Laura P. Stabile; Simon C. Watkins; Jianhua Xing; Shilpa Sant
Source: check_circle
Crossref

Supplementary Data from Targeting the Temporal Dynamics of Hypoxia-Induced Tumor-Secreted Factors Halts Tumor Migration

2023-03-31 | Preprint
Contributors: Manjulata Singh; Xiao-Jun Tian; Vera S. Donnenberg; Alan M. Watson; JingYu Zhang; Laura P. Stabile; Simon C. Watkins; Jianhua Xing; Shilpa Sant
Source: check_circle
Crossref

Supplementary Data from Targeting the Temporal Dynamics of Hypoxia-Induced Tumor-Secreted Factors Halts Tumor Migration

2023-03-31 | Preprint
Contributors: Manjulata Singh; Xiao-Jun Tian; Vera S. Donnenberg; Alan M. Watson; JingYu Zhang; Laura P. Stabile; Simon C. Watkins; Jianhua Xing; Shilpa Sant
Source: check_circle
Crossref

Reconstructing data-driven governing equations for cell phenotypic transitions: integration of data science and systems biology

Physical Biology
2022-11-01 | Journal article
Contributors: Jianhua Xing
Source: check_circle
Crossref

Mapping transcriptomic vector fields of single cells

Cell
2022-02 | Journal article
Part of ISSN: 0092-8674
Source: Self-asserted source
Jianhua Xing

Epithelial-to-mesenchymal transition proceeds through directional destabilization of multidimensional attractor

eLife
2022-02-21 | Journal article
Contributors: Weikang Wang; Dante Poe; Yaxuan Yang; Thomas Hyatt; Jianhua Xing
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Crossref

Normal mode analysis of membrane protein dynamics using the vibrational subsystem analysis

The Journal of Chemical Physics
2021-05-21 | Journal article
Contributors: Yan Zhang; She Zhang; Jianhua Xing; Ivet Bahar
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Crossref

Live-cell imaging and analysis reveal cell phenotypic transition dynamics inherently missing in snapshot data

Science Advances
2020-09-04 | Journal article
Contributors: Weikang Wang; Diana Douglas; Jingyu Zhang; Sangeeta Kumari; Metewo Selase Enuameh; Yan Dai; Callen T. Wallace; Simon C. Watkins; Weiguo Shu; Jianhua Xing
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Crossref

Sequential Wnt Agonist Then Antagonist Treatment Accelerates Tissue Repair and Minimizes Fibrosis

iScience
2020-05 | Journal article
Contributors: Xiao-Jun Tian; Dong Zhou; Haiyan Fu; Rong Zhang; Xiaojie Wang; Sui Huang; Youhua Liu; Jianhua Xing
Source: check_circle
Crossref

Bidirectional interplay between physical and biological approaches on studying the epithelial-to-mesenchymal transition

Physical Biology
2020-02-28 | Journal article
Contributors: Jianhua Xing
Source: check_circle
Crossref

Targeting the Temporal Dynamics of Hypoxia-Induced Tumor-Secreted Factors Halts Tumor Migration

Cancer Research
2019-06-01 | Journal article
Contributors: Manjulata Singh; Xiao-Jun Tian; Vera S. Donnenberg; Alan M. Watson; JingYu Zhang; Laura P. Stabile; Simon C. Watkins; Jianhua Xing; Shilpa Sant
Source: check_circle
Crossref

Investigating epithelial-to-mesenchymal transition with integrated computational and experimental approaches

Physical Biology
2019-03-07 | Journal article
Contributors: Jianhua Xing; Xiao-Jun Tian
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Crossref

Spatial clustering and common regulatory elements correlate with coordinated gene expression

PLOS Computational Biology
2019-03-01 | Journal article
Contributors: Jingyu Zhang; Ilya Ioshikhes; Hengyu Chen; Ruoyan Li; David A. Taft; Guang Yao; Fan Bai; Jianhua Xing
Source: check_circle
Crossref

Pathway crosstalk enables cells to interpret TGF-β duration

npj Systems Biology and Applications
2018-05-28 | Journal article
Contributors: Jingyu Zhang; Xiao-Jun Tian; Yi-Jiun Chen; Weikang Wang; Simon Watkins; Jianhua Xing
Source: check_circle
Crossref

Targeting temporal dynamics of microenvironmental factors halts tumor migration and alleviates effects of dynamic tumor heterogeneity

2017-09-20 | Preprint
Contributors: Manjulata Singh; Xiao-Jun Tian; Vera S. Donnenberg; Alan M Watson; Jingyu Zhang; Laura P. Stabile; Simon C. Watkins; Jianhua Xing; Shilpa Sant
Source: check_circle
Crossref

Signal Transduction Pathways of EMT Induced by TGF-β, SHH, and WNT and Their Crosstalks

Journal of Clinical Medicine
2016-03 | Journal article
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Multidisciplinary Digital Publishing Institute
grade
Preferred source (of 2)‎

Mathematical models of the transitions between endocrine therapy responsive and resistant states in breast cancer.

Journal of the Royal Society, Interface / the Royal Society
2014 | Journal article
DOI:

10.1098/rsif.2014.0206

Part of ISSN:

1742-5662

Contributors: Chen, Chun; Baumann, William T; Xing, Jianhua; Xu, Lingling; Clarke, Robert; Tyson, John J
Source: Self-asserted source
Jianhua Xing via ResearcherID

Statistical Mechanics Model for the Dynamics of Collective Epigenetic Histone Modification

Physical Review Letters
2014 | Journal article
DOI:

10.1103/PhysRevLett.112.068101

Part of ISSN:

0031-9007;1079-7114

Contributors: Zhang, Hang; Tian, Xiao-Jun; Mukhopadhyay, Abhishek; Kim, K. S.; Xing, Jianhua
Source: Self-asserted source
Jianhua Xing via ResearcherID

Systematic reverse engineering of network topologies: a case study of resettable bistable cellular responses.

2014 | Journal article
DOI:

10.1371/journal.pone.0105833

PMID:

25170839

PMC:

PMC4149494

Contributors: Mondal D; Dougherty E; Mukhopadhyay A; Carbo A; Yao G; Xing J
Source: Self-asserted source
Jianhua Xing via Europe PubMed Central

TGF-β–induced epithelial-to-mesenchymal transition proceeds through stepwise activation of multiple feedback loops

Science Signaling
2014-09-30 | Journal article
DOI:

10.1126/scisignal.2005304

Source: Self-asserted source
Jianhua Xing

Coupled Reversible and Irreversible Bistable Switches Underlying TGF beta-induced Epithelial to Mesenchymal Transition

Biophysical Journal
2013 | Journal article
DOI:

10.1016/j.bpj.2013.07.011

Part of ISSN:

0006-3495

Contributors: Tian, Xiao-Jun; Zhang, Hang; Xing, Jianhua
Source: Self-asserted source
Jianhua Xing via ResearcherID

Tumor-Specific Chromosome Mis-Segregation Controls Cancer Plasticity by Maintaining Tumor Heterogeneity

Plos One
2013 | Journal article
DOI:

10.1371/journal.pone.0080898

Part of ISSN:

1932-6203

Contributors: Hu, Yuanjie; Ru, Ning; Xiao, Huasheng; Chaturbedi, Abhishek; Hoa, Neil T.; Tian, Xiao-Jun; Zhang, Hang; Ke, Chao; Yan, Fengrong; Nelson, Jodi et al.
Source: Self-asserted source
Jianhua Xing via ResearcherID

A simple theoretical framework for understanding heterogeneous differentiation of CD4(+) T cells

Bmc Systems Biology
2012 | Journal article
DOI:

10.1186/1752-0509-6-66

Part of ISSN:

1752-0509

Contributors: Hong, Tian; Xing, Jianhua; Li, Liwu; Tyson, John J.
Source: Self-asserted source
Jianhua Xing via ResearcherID

A strategy to study pathway cross-talks of cells under repetitive exposure to stimuli

Bmc Systems Biology
2012 | Journal article
DOI:

10.1186/1752-0509-6-S3-S6

Part of ISSN:

1752-0509

Contributors: Fu, Yan; Jiang, Xiaoshan; Zhang, Hang; Xing, Jianhua
Source: Self-asserted source
Jianhua Xing via ResearcherID

Comparative Studies of Microtubule Mechanics with Two Competing Models Suggest Functional Roles of Alternative Tubulin Lateral Interactions

Biophysical Journal
2012 | Journal article
DOI:

10.1016/j.bpj.2012.05.003

Contributors: Wu, Zhanghan; Nogales, Eva; Xing, Jianhua
Source: Self-asserted source
Jianhua Xing via ResearcherID

Fluctuation-dissipation relations for steady-state systems

Epl
2012 | Journal article
DOI:

10.1209/0295-5075/100/20001

Part of ISSN:

0295-5075

Contributors: Xing, Jianhua; Mu, Weihua; Ou-Yang, Zhongcan
Source: Self-asserted source
Jianhua Xing via ResearcherID

Functional Roles of Slow Enzyme Conformational Changes in Network Dynamics

Biophysical Journal
2012 | Journal article
DOI:

10.1016/j.bpj.2012.08.008

Part of ISSN:

0006-3495

Contributors: Wu, Zhanghan; Xing, Jianhua
Source: Self-asserted source
Jianhua Xing via ResearcherID

Molecular Mechanism Underlying Persistent Induction of LCN2 by Lipopolysaccharide in Kidney Fibroblasts

Plos One
2012 | Journal article
DOI:

10.1371/journal.pone.0034633

Contributors: Glaros, Trevor; Fu, Yan; Xing, Jianhua; Li, Liwu
Source: Self-asserted source
Jianhua Xing via ResearcherID

Network Topologies and Dynamics Leading to Endotoxin Tolerance and Priming in Innate Immune Cells

Biophysical Journal
2012 | Journal article
Part of ISSN:

0006-3495

Contributors: Fu, Yan; Glaros, Trevor; Zhu, Meng; Wang, Ping; Wu, Zhanghan; Tyson, John; Li, Liwu; Xing, Jianhua
Source: Self-asserted source
Jianhua Xing via ResearcherID

Reconciling heterogeneous differentiation of CD4+T cells by systems-level modeling

Journal of Immunology
2012 | Journal article
Part of ISSN:

0022-1767

Contributors: Hong, Tian; Xing, Jianhua; Li, Liwu; Tyson, John
Source: Self-asserted source
Jianhua Xing via ResearcherID

A Mathematical Model for the Reciprocal Differentiation of T Helper 17 Cells and Induced Regulatory T Cells

Plos Computational Biology
2011 | Journal article
DOI:

e1002122 10.1371/journal.pcbi.1002122

Part of ISSN:

1553-734X

Contributors: Hong, Tian; Xing, Jianhua; Li, Liwu; Tyson, John J.
Source: Self-asserted source
Jianhua Xing via ResearcherID

Application of the projection operator formalism to non-Hamiltonian dynamics

Journal of Chemical Physics
2011 | Journal article
DOI:

044132 10.1063/1.3530071

Part of ISSN:

0021-9606

Contributors: Xing, Jianhua; Kim, K. S.
Source: Self-asserted source
Jianhua Xing via ResearcherID

Mapping between dissipative and Hamiltonian systems

Journal of Physics a-Mathematical and Theoretical
2010 | Journal article
DOI:

375003 10.1088/1751-8113/43/37/375003

Part of ISSN:

1751-8113

Contributors: Xing, Jianhua
Source: Self-asserted source
Jianhua Xing via ResearcherID

Resonant activation: a strategy against bacterial persistence

Physical Biology
2010 | Journal article
DOI:

016013 10.1088/1478-3975/7/1/016013

Part of ISSN:

1478-3967

Contributors: Fu, Yan; Zhu, Meng; Xing, Jianhua
Source: Self-asserted source
Jianhua Xing via ResearcherID

Amplification and Detection of Single-Molecule Conformational Fluctuation through a Protein Interaction Network with Bimodal Distributions

Journal of Physical Chemistry B
2009 | Journal article
DOI:

10.1021/jp903548d

Part of ISSN:

1520-6106

Contributors: Wu, Zhanghan; Elgart, Vlad; Qian, Hong; Xing, Jianhua
Source: Self-asserted source
Jianhua Xing via ResearcherID

Model Studies of the Dynamics of Bacterial Flagellar Motors

Biophysical Journal
2009 | Journal article
DOI:

10.1016/j.bpj.2009.01.023

Part of ISSN:

0006-3495

Contributors: Bai, Fan; Lo, Chien-Jung; Berry, Richard M.; Xing, Jianhua
Source: Self-asserted source
Jianhua Xing via ResearcherID

Simulations of Tubulin Sheet Polymers as Possible Structural Intermediates in Microtubule Assembly

Plos One
2009 | Journal article
DOI:

e7291 10.1371/journal.pone.0007291

Part of ISSN:

1932-6203

Contributors: Wu, Zhanghan; Wang, Hong-Wei; Mu, Weihua; Ouyang, Zhongcan; Nogales, Eva; Xing, Jianhua
Source: Self-asserted source
Jianhua Xing via ResearcherID

Stochastic bifurcation, slow fluctuations, and bistability as an origin of biochemical complexity

Physical Chemistry Chemical Physics
2009 | Journal article
DOI:

10.1039/b900335p

Part of ISSN:

1463-9076

Contributors: Qian, Hong; Shi, Pei-Zhe; Xing, Jianhua
Source: Self-asserted source
Jianhua Xing via ResearcherID

The Goldbeter-Koshland Switch in the First-Order Region and Its Response to Dynamic Disorder

Plos One
2008 | Journal article
DOI:

10.1371/journal.pone.0002140

Contributors: Xing, Jianhua; Chen, Jing
Source: Self-asserted source
Jianhua Xing via ResearcherID

Nonequilibrium dynamic mechanism for allosteric effect

Physical Review Letters
2007 | Journal article
DOI:

10.1103/PhysRevLett.99.168103

Part of ISSN:

0031-9007

Contributors: Xing, Jianhua
Source: Self-asserted source
Jianhua Xing via ResearcherID

Protein fluctuations and breakdown of time-scale separation in rate theories

Physical Review E
2006 | Journal article
DOI:

10.1103/PhysRevE.74.061911

Part of ISSN:

1539-3755

Contributors: Xing, Jianhua; Kim, K. S.
Source: Self-asserted source
Jianhua Xing via ResearcherID
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Peer review (17 reviews for 14 publications/grants)

Review activity for Advanced science. (1)
Review activity for Biophysical journal. (1)
Review activity for BMC biology. (1)
Review activity for Cell reports. (1)
Review activity for Cell reports. (1)
Review activity for Computational and Structural Biotechnology Journal (2)
Review activity for Genome biology. (1)
Review activity for Journal of Advanced Research (1)
Review activity for Multiscale modeling & simulation : (2)
Review activity for Nature communications (2)
Review activity for Nature methods. (1)
Review activity for npj systems biology and applications. (1)
Review activity for PLoS computational biology. (1)
Review activity for Review Commons (1)