Mario Buffelli (0000-0002-3709-013X)

Personal information

Biography

Personal Statement

I am an Associate Professor of Physiology, and my research is focused on the molecular, structural and functional mechanisms regulating neuronal plasticity in physiological and pathological conditions. In particular, I am investigating: 1) the mechanisms underlying dendritic spine formation and turnover, which are crucial to all aspects of neuronal morphology and function, in cortex and in hippocampus in animal models of Alzheimer’s disease, autism and other neurological diseases; 2) the role of glia (microglia and astrocytes) in the formation of synaptic contacts, axonal growth, neurogenesis, neurodegeneration, neoplastic growth and apoptosis.

I have a broad background in vitro, ex vivo and in vivo studies. As PI or co-Investigator I received research funding from Italian Ministry of Education, University and Research, Italian Ministry of Health, University of Verona, and private foundations as Telethon-Italy, Fondazione Cariverona-Italy, Fondazione Fibrosi Cistica-Italy, and Alzheimer’s Association-US. In summary, I have the expertise, leadership, training, expertise and motivation necessary to collaborate on the proposed research project.

Activities

Collapse all

University of Verona: Verona, IT

2006 to present | Associate professor of physiology (Dept. of Neurological Sciences)

Employment

Mario Buffelli

https://orcid.org/0000-0002-3709-013X

Personal information

Websites & social links

Other IDs

Keywords

Countries

Biography

Activities

Employment (3)

University of Verona: Verona, IT

University of Verona: Verona, IT

Washington University: Saint Louis, US

Education and qualifications (2)

University of Verona: Verona, IT

University of Verona: Verona, IT

Works (50 of 65)

Stable ubiquitin conjugation for biological interrogation of ubiquitinated tau repeat domain

Increased Expression of Autophagy-Related Genes in Alzheimer’s Disease—Type 2 Diabetes Mellitus Comorbidity Models in Cells

Editorial: Non-invasive brain stimulation techniques in neurological and neuropsychiatric disorders: Physiological and molecular evidence

In vivo morphological alterations of TAMs during KCa3.1 inhibition—by using in vivo two-photon time-lapse technology

High-frequency rTMS modulates emotional behaviors and structural plasticity in layers II/III and V of the mPFC

Early Application of Ipsilateral Cathodal-tDCS in a Mouse Model of Brain Ischemia Results in Functional Improvement and Perilesional Microglia Modulation

High-frequency repetitive transcranial magnetic stimulation enhances layer II/III morphological dendritic plasticity in mouse primary motor cortex

Therapeutic targeting of Lyn kinase to treat chorea-acanthocytosis.

An improved and simplified protocol to combine Golgi-Cox staining with immunofluorescence and transmission electron microscopy techniques

The Effects of 1-Hz rTMS on Emotional Behavior and Dendritic Complexity of Mature and Newly Generated Dentate Gyrus Neurons in Male Mice

Intranasal delivery of mesenchymal stem cell‐derived extracellular vesicles exerts immunomodulatory and neuroprotective effects in a 3xTg model of Alzheimer's disease

Transcranial direct current stimulation of the mouse prefrontal cortex modulates serotonergic neural activity of the dorsal raphe nucleus

Neurodegeneration-Associated Proteins in Human Olfactory Neurons Collected by Nasal Brushing

Glucocorticoid receptors modulate dendritic spine plasticity and microglia activity in an animal model of Alzheimer's disease

Cystic fibrosis transmembrane conductance regulator functional evaluations in a G542X+/- IVS8Tn:T7/9 patient with acute recurrent pancreatitis

Can Single Shell Diffusion MRI Detect Synaptic Plasticity in Mice?

Allosteric sodium binding cavity in GPR3: a novel player in modulation of Aβ production

Rac1 activation links tau hyperphosphorylation and Aβ dysmetabolism in Alzheimer’s disease

Autism-associated 16p11.2 microdeletion impairs prefrontal functional connectivity in mouse and human

Activity-dependent vs. neurotrophic modulation of acetylcholine receptor expression: Evidence from rat soleus and extensor digitorum longus muscles confirms the exclusive role of activity

Effective delivery of recombinant proteins to rod photoreceptors via lipid nanovesicles

Challenging the diagnosis of Cystic Fibrosis in a patient carrying the 186-8T/C allelic variant in the CF Transmembrane Conductance Regulator gene

Detection of CFTR protein in human leukocytes by flow cytometry

Distribution of different isoforms of receptor protein tyrosine phosphatase γ (Ptprg-RPTP γ) in adult mouse brain: Upregulation during neuroinflammation

Electrophysiological evaluation of Cystic Fibrosis Conductance Transmembrane Regulator (CFTR) expression in human monocytes

The Potential Role of Rho GTPases in Alzheimer's Disease Pathogenesis

Rescue of cognitive-aging by administration of a neurogenic and/or neurotrophic compound

HOMECAT: Consensus homologs mapping for interspecific knowledge transfer and functional genomic data integration

Impaired CFTR function in mild cystic fibrosis associated with the S977F/T5TG12complex allele in trans with F508del mutation

Rac1 Selective Activation Improves Retina Ganglion Cell Survival and Regeneration

Rho GTPase-dependent plasticity of dendritic spines in the adult brain

Two-Photon Microscopy Imaging of thy1GFP-M Transgenic Mice: A Novel Animal Model to Investigate Brain Dendritic Cell Subsets In Vivo

β-Amyloid-aluminum complex alters cytoskeletal stability and increases ROS production in cortical neurons

Glutamatergic neurons induce expression of functional glutamatergic synapses in primary myotubes

Mouse transgenic lines that selectively label type I, type IIa, and types IIX+B skeletal muscle fibers

Defective CFTR expression and function are detectable in blood monocytes: Development of a new blood test for cystic fibrosis

Astrocytes regulate the expression of insulin-like growth factor 1 receptor (IGF1-R) in primary cortical neurons during in vitro senescence

Brain plasticity and functionality explored by nonlinear optical microscopy

The timing of impulse activity shapes the process of synaptic competition at the neuromuscular junction

Developmental axonal pruning and synaptic plasticity

Genetic perturbation of postsynaptic activity regulates synapse elimination in developing cerebellum

Glutamatergic reinnervation and assembly of glutamatergic synapses in adult rat skeletal muscle occurs at cholinergic endplates

On the mechanism of action of muscle fibre activity in synapse competition and elimination at the mammalian neuromuscular junction

Impaired nerve regeneration in reeler mice after peripheral nerve injury

In vivo multi-photon nanosurgery on cortical neurons: Focusing on network organization

In vivo micro-lesion of single dendrite with femtosecond laser pulses

In vivo micro-lesion of single dendrite with femtosecond laser pulses

In vivo multiphoton nanosurgery on cortical neurons

Laser-induced microlesion of single dendrites in living mice

Synapse formation and elimination: Role of activity studied in different models of adult muscle reinnervation