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Employment (3)

Genentech: South San Francisco, California, US

2022-10-10 to present | Principal Scientist and Group Leader (Structural Biology)
Employment
Source: Self-asserted source
John Nicoludis

Invitae Corporation: San Francisco, CA, US

2020-03-23 to 2022-09-18 | Computational Biologist and Team Lead (Knowledge and Inference) (Clinical Science & Interpretation)
Employment
Source: Self-asserted source
John Nicoludis

University of California San Francisco: San Francisco, CA, US

2018-05-07 to 2020-03-16 | Postdoctoral fellow (Pharmaceutical Chemistry)
Employment
Source: Self-asserted source
John Nicoludis

Education and qualifications (2)

Harvard University: Cambridge, MA, US

2012-09-01 to 2018-05-25 | PhD (Chemistry and Chemical Biology)
Education
Source: Self-asserted source
John Nicoludis

Swarthmore College: Swarthmore, PA, US

2008-09-01 to 2012-06-01 | BA in Biochemistry (Chemistry and Biochemistry)
Education
Source: Self-asserted source
John Nicoludis

Works (15)

Transient water wires mediate selective proton transport in designed channel proteins

Nature Chemistry
2023-07 | Journal article
DOI: 10.1038/s41557-023-01210-4
Contributors: Huong T. Kratochvil; Laura C. Watkins; Marco Mravic; Jessica L. Thomaston; John M. Nicoludis; Noah H. Somberg; Lijun Liu; Mei Hong; Gregory A. Voth; William F. DeGrado
Source: check_circle
Crossref

Crystal structure of a three-tetrad, parallel, K+-stabilized human telomeric G-quadruplex at 1.35 Å resolution

Acta Crystallographica Section F Structural Biology Communications
2023-06-01 | Journal article
DOI: 10.1107/S2053230X23003977
Contributors: E. V. Chen; J. M. Nicoludis; B. M. Powell; K. S. Li; L. A. Yatsunyk
Source: check_circle
Crossref

Interaction specificity of clustered protocadherins inferred from sequence covariation and structural analysis

Proceedings of the National Academy of Sciences
2019-09-03 | Journal article
DOI: 10.1073/pnas.1821063116
Contributors: John M. Nicoludis; Anna G. Green; Sanket Walujkar; Elizabeth J. May; Marcos Sotomayor; Debora S. Marks; Rachelle Gaudet
Source: check_circle
Crossref

Structures in multiple conformations reveal distinct transition metal and proton pathways in an Nramp transporter

eLife
2019-02-04 | Journal article
DOI: 10.7554/eLife.41124
Contributors: Aaron T Bozzi; Christina M Zimanyi; John M Nicoludis; Brandon K Lee; Casey H Zhang; Rachelle Gaudet
Source: check_circle
Crossref

Interaction specificity of clustered protocadherins inferred from sequence covariation and structural analysis

2018-12-11 | Other
DOI: 10.1101/493106
Contributors: John M. Nicoludis; Anna G. Green; Sanket Walujkar; Elizabeth J. May; Marcos Sotomayor; Debora S. Marks; Rachelle Gaudet
Source: check_circle
Crossref

Structures in multiple conformations reveal distinct transition metal and proton pathways in an Nramp transporter

2018-08-29 | Other
DOI: 10.1101/403014
Contributors: Aaron T. Bozzi; Christina M. Zimanyi; John M. Nicoludis; Brandon K. Lee; Casey H. Zhang; Rachelle Gaudet
Source: check_circle
Crossref

Applications of sequence coevolution in membrane protein biochemistry.

Biochimica et biophysica acta. Biomembranes
2017-10 | Journal article
DOI: 10.1016/j.bbamem.2017.10.004
PMID: 28993150
Contributors: Nicoludis JM; Gaudet R
Source: Self-asserted source
John Nicoludis via Europe PubMed Central

Antiparallel protocadherin homodimers use distinct affinity- and specificity-mediating regions in cadherin repeats 1-4.

eLife
2016-07 | Journal article
DOI: 10.7554/eLife.18449
PMID: 27472898
PMC: PMC5001838
Contributors: Nicoludis JM; Vogt BE; Green AG; Schärfe CP; Marks DS; Gaudet R
Source: Self-asserted source
John Nicoludis via Europe PubMed Central

Investigation of the interactions between Pt(II) and Pd(II) derivatives of 5,10,15,20-tetrakis (N-methyl-4-pyridyl) porphyrin and G-quadruplex DNA.

Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry
2016-01 | Journal article
DOI: 10.1007/s00775-015-1325-8
PMID: 26748794
PMC: PMC4801998
Contributors: Sabharwal NC; Mendoza O; Nicoludis JM; Ruan T; Mergny JL; Yatsunyk LA
Source: Self-asserted source
John Nicoludis via Europe PubMed Central

Structure and Sequence Analyses of Clustered Protocadherins Reveal Antiparallel Interactions that Mediate Homophilic Specificity.

Structure (London, England : 1993)
2015-10 | Journal article
DOI: 10.1016/j.str.2015.09.005
PMID: 26481813
PMC: PMC4635037
Contributors: Nicoludis JM; Lau SY; Schärfe CP; Marks DS; Weihofen WA; Gaudet R
Source: Self-asserted source
John Nicoludis via Europe PubMed Central

N-methylmesoporphyrin IX fluorescence as a reporter of strand orientation in guanine quadruplexes.

The FEBS journal
2014-02 | Journal article
DOI: 10.1111/febs.12734
PMID: 24494857
PMC: PMC4163640
Contributors: Sabharwal NC; Savikhin V; Turek-Herman JR; Nicoludis JM; Szalai VA; Yatsunyk LA
Source: Self-asserted source
John Nicoludis via Europe PubMed Central

Optimized end-stacking provides specificity of N-methyl mesoporphyrin IX for human telomeric G-quadruplex DNA.

Journal of the American Chemical Society
2012-12 | Journal article
DOI: 10.1021/ja3088746
PMID: 23181361
Contributors: Nicoludis JM; Miller ST; Jeffrey PD; Barrett SP; Rablen PR; Lawton TJ; Yatsunyk LA
Source: Self-asserted source
John Nicoludis via Europe PubMed Central

Interaction of human telomeric DNA with N-methyl mesoporphyrin IX.

Nucleic acids research
2012-02 | Journal article
DOI: 10.1093/nar/gks152
PMID: 22362740
PMC: PMC3384297
Contributors: Nicoludis JM; Barrett SP; Mergny JL; Yatsunyk LA
Source: Self-asserted source
John Nicoludis via Europe PubMed Central

Induction of G-quadruplex DNA structure by Zn(II) 5,10,15,20-tetrakis(N-methyl-4-pyridyl)porphyrin.

Biochimie
2011-06 | Journal article
DOI: 10.1016/j.biochi.2011.05.038
PMID: 21679743
Contributors: Bhattacharjee AJ; Ahluwalia K; Taylor S; Jin O; Nicoludis JM; Buscaglia R; Brad Chaires J; Kornfilt DJ; Marquardt DG; Yatsunyk LA
Source: Self-asserted source
John Nicoludis via Europe PubMed Central

Rudimentary G-quadruplex-based telomere capping in Saccharomyces cerevisiae.

Nature structural & molecular biology
2011-03 | Journal article
DOI: 10.1038/nsmb.2033
PMID: 21399640
PMC: PMC3119813
Contributors: Smith JS; Chen Q; Yatsunyk LA; Nicoludis JM; Garcia MS; Kranaster R; Balasubramanian S; Monchaud D; Teulade-Fichou MP; Abramowitz L et al.
Source: Self-asserted source
John Nicoludis via Europe PubMed Central
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