Personal information

Activities

Employment (3)

Albany Medical College: Albany, NY, US

2001-03-01 to present | Professor (Depts Surgery and Regenerative & Cancer Cell Biology)
Employment
Source: Self-asserted source
Livingston Van De Water

Massachusetts General Hospital and Shriners Hospital: Boston, MA, US

1996-07-01 to 2001-02-28 | Assistant and Associate Professor, Harvard Med. (Surgery )
Employment
Source: Self-asserted source
Livingston Van De Water

Beth Israel Deaconess Medical Center: Boston, MA, US

1981-09-01 to 1996-06-30 | Instructor, Assistant Professor (Pathology)
Employment
Source: Self-asserted source
Livingston Van De Water

Education and qualifications (2)

Massachusetts Institute of Technology: Cambridge, MA, US

1979-09-01 to 1981-08-31 | Postdoc (Center for Cancer Research, Dept Biology)
Qualification
Source: Self-asserted source
Livingston Van De Water

University of Rochester: Rochester, NY, US

1973-09-01 to 1979-08-31 | Ph.D. (Biology)
Education
Source: Self-asserted source
Livingston Van De Water

Funding (4)

Keratinocyte Integrin Crosstalk During Wound Healing

2013-02-20 to 2018-12-31 | Grant
National Institute of Arthritis and Musculoskeletal and Skin Diseases (Bethesda, US)
GRANT_NUMBER: R01AR063778
Source: Self-asserted source
Livingston Van De Water via DimensionsWizard

Matrix Regulation of Cell Function During Wound Healing

1997-08-01 to 2012-08-31 | Grant
National Institute of General Medical Sciences (Bethesda, US)
GRANT_NUMBER: R01GM056442
Source: Self-asserted source
Livingston Van De Water via DimensionsWizard

FIBRONECTINS IN CHRONIC WOUND HEALING

1994-09-21 to 1996-09-20 | Grant
National Institute of General Medical Sciences (Bethesda, US)
GRANT_NUMBER: R55GM052552
Source: Self-asserted source
Livingston Van De Water via DimensionsWizard

PATHOBIOLOGY OF MACROPHAGE-FIBRONECTIN INTERACTIONS

1986-12-01 to 1994-11-30 | Grant
National Institute of General Medical Sciences (Bethesda, US)
GRANT_NUMBER: R01GM036812
Source: Self-asserted source
Livingston Van De Water via DimensionsWizard

Works (50 of 67)

Items per page:
Page 1 of 2

Loss of Integrin α9β1 on Tumor Keratinocytes Enhances the Stromal Vasculature and Growth of Cutaneous Tumors

Journal of Investigative Dermatology
2022-07 | Journal article
Contributors: Scott D. Varney; Lei Wu; Whitney M. Longmate; C. Michael DiPersio; Livingston Van De Water
Source: check_circle
Crossref

Integrin α4β1 is required for IL‐1α‐ and Nrf2‐dependent, Cox‐2 induction in fibroblasts, supporting a mechanism that suppresses α‐SMA expression

Wound Repair and Regeneration
2021-07 | Journal article
Contributors: Rui Zheng; Scott D. Varney; Lei Wu; C. Michael DiPersio; Livingston Van De Water
Source: check_circle
Crossref

Epidermal Integrin α3β1 Regulates Tumor-Derived Proteases BMP-1, Matrix Metalloprotease-9, and Matrix Metalloprotease-3

JID Innovations
2021-06 | Journal article
Contributors: Whitney M. Longmate; Rakshitha Pandulal Miskin; Livingston Van De Water; C. Michael DiPersio
Source: check_circle
Crossref

Integrin α3β1 on Tumor Keratinocytes Is Essential to Maintain Tumor Growth and Promotes a Tumor-Supportive Keratinocyte Secretome

Journal of Investigative Dermatology
2021-01 | Journal article
Contributors: Whitney M. Longmate; Scott Varney; Derek Power; Rakshitha Pandulal Miskin; Karl E. Anderson; Lori DeFreest; Livingston Van De Water; C. Michael DiPersio
Source: check_circle
Crossref

Keratinocyte Integrin α3β1 Promotes Secretion of IL-1α to Effect Paracrine Regulation of Fibroblast Gene Expression and Differentiation

Journal of Investigative Dermatology
2019-09 | Journal article
Contributors: Rui Zheng; Whitney M. Longmate; Lori DeFreest; Scott Varney; Lei Wu; C. Michael DiPersio; Livingston Van De Water
Source: check_circle
Crossref

Opposing Roles of Epidermal Integrins α3β1 and α9β1 in Regulation of mTLD/BMP-1–Mediated Laminin-γ2 Processing during Wound Healing

Journal of Investigative Dermatology
2018 | Journal article
EID:

2-s2.0-85041664062

Contributors: Longmate, W.M.; Lyons, S.P.; DeFreest, L.; Van De Water, L.; DiPersio, C.M.
Source: Self-asserted source
Livingston Van De Water via Scopus - Elsevier

Suppression of integrin α3β1 by α9β1 in the epidermis controls the paracrine resolution of wound angiogenesis

Journal of Cell Biology
2017 | Journal article
EID:

2-s2.0-85021841641

Contributors: Longmate, W.M.; Lyons, S.P.; Chittur, S.V.; Pumiglia, K.M.; Van De Water, L.; DiPersio, C.M.
Source: Self-asserted source
Livingston Van De Water via Scopus - Elsevier

Hic-5 is required for myofibroblast differentiation by regulating mechanically dependent MRTF-A nuclear accumulation

Journal of Cell Science
2016 | Journal article
EID:

2-s2.0-84961219361

Contributors: Varney, S.D.; Betts, C.B.; Zheng, R.; Wu, L.; Hinz, B.; Zhou, J.; Van De Water, L.
Source: Self-asserted source
Livingston Van De Water via Scopus - Elsevier

Integrin-mediated regulation of epidermal wound functions

Cell and Tissue Research
2016 | Journal article
EID:

2-s2.0-84976339043

Contributors: DiPersio, C.M.; Zheng, R.; Kenney, J.; Van De Water, L.
Source: Self-asserted source
Livingston Van De Water via Scopus - Elsevier

Control of cell migration through mRNA localization and local translation

Wiley Interdisciplinary Reviews: RNA
2015 | Journal article
EID:

2-s2.0-84916599802

Contributors: Liao, G.; Mingle, L.; Van De Water, L.; Liu, G.
Source: Self-asserted source
Livingston Van De Water via Scopus - Elsevier

Matrix compliance and the regulation of cytokinesis

Biology Open
2015 | Journal article
EID:

2-s2.0-84979763323

Contributors: Sambandamoorthy, S.; Mathew-Steiner, S.; Varney, S.; Zuidema, J.M.; Gilbert, R.J.; Van Water, L.D.; LaFlamme, S.E.
Source: Self-asserted source
Livingston Van De Water via Scopus - Elsevier

The α4β1 integrin and the EDA domain of fibronectin regulate a profibrotic phenotype in dermal fibroblasts

Matrix Biology
2015 | Journal article
EID:

2-s2.0-84922746881

Contributors: Shinde, A.V.; Kelsh, R.; Peters, J.H.; Sekiguchi, K.; Van De Water, L.; McKeown-Longo, P.J.
Source: Self-asserted source
Livingston Van De Water via Scopus - Elsevier

The group A streptococcal collagen-like protein-1, Scl1, mediates biofilm formation by targeting the extra domain A-containing variant of cellular fibronectin expressed in wounded tissue

Molecular Microbiology
2013 | Journal article
EID:

2-s2.0-84873056871

Contributors: Oliver-Kozup, H.; Martin, K.H.; Schwegler-Berry, D.; Green, B.J.; Betts, C.; Shinde, A.V.; Van De Water, L.; Lukomski, S.
Source: Self-asserted source
Livingston Van De Water via Scopus - Elsevier

Transforming growth factor-β1-induced transcript 1 protein, a novel marker for smooth muscle contractile phenotype, is regulated by serum response factor/myocardin protein

Journal of Biological Chemistry
2011 | Journal article
EID:

2-s2.0-82355171907

Contributors: Wang, X.; Hu, G.; Betts, C.; Harmon, E.Y.; Keller, R.S.; Van De Water, L.; Zhou, J.
Source: Self-asserted source
Livingston Van De Water via Scopus - Elsevier

Loss of integrin alpha9beta1 results in defects in proliferation, causing poor re-epithelialization during cutaneous wound healing.

The Journal of investigative dermatology
2009 | Journal article
EID:

2-s2.0-58149332702

Contributors: Singh, P.; Chen, C.; Pal-Ghosh, S.; Stepp, M.A.; Sheppard, D.; Van De Water, L.
Source: Self-asserted source
Livingston Van De Water via Scopus - Elsevier

Hic-5 promotes the hypertrophic scar myofibroblast phenotype by regulating the TGF-β1 autocrine loop

Journal of Investigative Dermatology
2008 | Journal article
EID:

2-s2.0-51749095919

Contributors: Dabiri, G.; Tumbarello, D.A.; Turner, C.E.; Van De Water, L.
Source: Self-asserted source
Livingston Van De Water via Scopus - Elsevier

Identification of the peptide sequences within the EIIIA (EDA) segment of fibronectin that mediate integrin α9β1-dependent cellular activities

Journal of Biological Chemistry
2008 | Journal article
EID:

2-s2.0-41449111120

Contributors: Shinde, A.V.; Bystroff, C.; Wang, C.; Vogelezang, M.G.; Vincent, P.A.; Hynes, R.O.; Van De Water, L.
Source: Self-asserted source
Livingston Van De Water via Scopus - Elsevier

TGF-β1 slows the growth of pathogenic myofibroblasts through a mechanism requiring the focal adhesion protein, Hic-5

Journal of Investigative Dermatology
2008 | Journal article
EID:

2-s2.0-38149081248

Contributors: Dabiri, G.; Tumbarello, D.A.; Turner, C.E.; Van De Water, L.
Source: Self-asserted source
Livingston Van De Water via Scopus - Elsevier

Manganese superoxide dismutase enhances the invasive and migratory activity of tumor cells

Cancer Research
2007 | Journal article
EID:

2-s2.0-35948936350

Contributors: Connor, K.M.; Hempel, N.; Nelson, K.K.; Dabiri, G.; Gamarra, A.; Belarmino, J.; Van De Water, L.; Mian, B.M.; Melendez, J.A.
Source: Self-asserted source
Livingston Van De Water via Scopus - Elsevier

The fibronectin synergy site modulates TGF-β-dependent fibroblast contraction

Biochemical and Biophysical Research Communications
2007 | Journal article
EID:

2-s2.0-34447558364

Contributors: Meckmongkol, T.T.; Harmon, R.; McKeown-Longo, P.; Van De Water, L.
Source: Self-asserted source
Livingston Van De Water via Scopus - Elsevier

A TGF-β1-dependent autocrine loop regulates the structure of focal adhesions in hypertrophic scar fibroblasts

Journal of Investigative Dermatology
2006 | Journal article
EID:

2-s2.0-33646159983

Contributors: Dabiri, G.; Campaner, A.; Morgan, J.R.; Van De Water, L.
Source: Self-asserted source
Livingston Van De Water via Scopus - Elsevier

Erratum: Influence of insulin therapy on burn wound healing in rats (Journal of Surgical Research (2003) 109 (92) DOI: 10.1016/S0022-4804(02)00036- 7)

Journal of Surgical Research
2005 | Journal article
EID:

2-s2.0-27144555324

Contributors: Madihally, S.V.; Solomon, V.; Mitchell, R.N.; Van De Water, L.; Yarmush, M.L.; Toner, M.
Source: Self-asserted source
Livingston Van De Water via Scopus - Elsevier

The spatial and temporal expression patterns of integrin α9β1 and one of its ligands, the EIIIA segment of fibronectin, in cutaneous wound healing

Journal of Investigative Dermatology
2004 | Journal article
EID:

2-s2.0-9744274523

Contributors: Singh, P.; Reimer, C.L.; Peters, J.H.; Stepp, M.A.; Hynes, R.O.; Van De Water, L.
Source: Self-asserted source
Livingston Van De Water via Scopus - Elsevier

Influence of insulin therapy on burn wound healing in rats

Journal of Surgical Research
2003 | Journal article
EID:

2-s2.0-0037297448

Contributors: Madibally, S.V.; Solomon, V.; Mitchell, R.N.; Van De Water, L.; Yarmush, M.L.; Toner, M.
Source: Self-asserted source
Livingston Van De Water via Scopus - Elsevier

Stimulation of extracellular matrix remodelling by the first type III repeat in fibronectin

Journal of Cell Science
2003 | Journal article
EID:

2-s2.0-0345328658

Contributors: Klein, R.M.; Zheng, M.; Ambesi, A.; Van De Water, L.; McKeown-Longo, P.J.
Source: Self-asserted source
Livingston Van De Water via Scopus - Elsevier

Myofibroblast activity in an animal model for human hypertrophic scar

American Society of Mechanical Engineers, Heat Transfer Division, (Publication) HTD
2002 | Conference paper
EID:

2-s2.0-0347514918

Contributors: Affonce, D.A.; Sojka, E.S.; Van De Water, L.; Sheridan, R.; Fowler, A.J.
Source: Self-asserted source
Livingston Van De Water via Scopus - Elsevier

The EIIIA segment of fibronectin is a ligand for integrins α9β1 and α9β1 providing a novel mechanism for regulating cell adhesion by alternative splicing

Journal of Biological Chemistry
2002 | Journal article
EID:

2-s2.0-0037177894

Contributors: Liao, Y.-F.; Gotwals, P.J.; Koteliansky, V.E.; Sheppard, D.; Van Water, L.D.
Source: Self-asserted source
Livingston Van De Water via Scopus - Elsevier

Fibrinogen and fibrin are anti-adhesive for keratinocytes: A mechanism for fibrin eschar slough during wound repair

Journal of Investigative Dermatology
2001 | Journal article
EID:

2-s2.0-0035671644

Contributors: Kubo, M.; Van De Water, L.; Plantefaber, L.C.; Mosesson, M.W.; Simon, M.; Tonnesen, M.G.; Taichman, L.; Clark, R.A.F.
Source: Self-asserted source
Livingston Van De Water via Scopus - Elsevier

Plasmin triggers rapid contraction and degradation of fibroblast- populated collagen lattices

Journal of Investigative Dermatology
2000 | Journal article
EID:

2-s2.0-0033993710

Contributors: Pins, G.D.; Collins-Pavao, M.E.; Van De Water, L.; Yarmush, M.L.; Morgan, J.R.
Source: Self-asserted source
Livingston Van De Water via Scopus - Elsevier

Simple devices to facilitate the analysis of collagen contraction by cells

BioTechniques
2000 | Journal article
EID:

2-s2.0-0033823088

Contributors: Tilles, A.W.; Classen, J.M.; Toner, M.; Van de Water, L.
Source: Self-asserted source
Livingston Van De Water via Scopus - Elsevier

VEGF expression by epithelial and stromal cell compartments

American Journal of Pathology
2000 | Journal article
EID:

2-s2.0-0033869868

Contributors: Senger, D.R.; Van De Water, L.
Source: Self-asserted source
Livingston Van De Water via Scopus - Elsevier

Identification of two amino acids within the EIIIA (ED-A) segment of fibronectin constituting the epitope for two function-blocking monoclonal antibodies

Journal of Biological Chemistry
1999 | Journal article
EID:

2-s2.0-0033580939

Contributors: Liao, Y.-F.; Wieder, K.G.; Classen, J.M.; Van De Water, L.
Source: Self-asserted source
Livingston Van De Water via Scopus - Elsevier

Vascular stroma formation in carcinoma in situ, invasive carcinoma, and metastatic carcinoma of the breast

Clinical Cancer Research
1999 | Journal article
EID:

2-s2.0-0032933778

Contributors: Brown, L.F.; Guidi, A.J.; Schnitt, S.J.; Van De Water, L.; Iruela-Arispe, M.L.; Yeo, T.-K.; Tognazzi, K.; Dvorak, H.F.
Source: Self-asserted source
Livingston Van De Water via Scopus - Elsevier

Blockade of very late antigen-4 integrin binding to fibronectin in allograft recipients: I. Treatment with connecting segment-1 peptides prevents acute rejection by suppressing intragraft mononuclear cell accumulation, endothelial activation, and cytokine expression

Transplantation
1998 | Journal article
EID:

2-s2.0-0032520802

Contributors: Coito, A.J.; Korom, S.; Graser, E.; Volk, H.-D.; Van De Water, L.; Kupiec-Weglinski, J.W.
Source: Self-asserted source
Livingston Van De Water via Scopus - Elsevier

Distinct fibronectin splicing variants: Potential targets for therapeutic immunomodulation in organ allograft recipients

Transplantation Proceedings
1997 | Journal article
EID:

2-s2.0-0030946678

Contributors: Coito, A.J.; Korom, S.; Van De Water, L.; Kupiec-Weglinski, J.W.
Source: Self-asserted source
Livingston Van De Water via Scopus - Elsevier

Expression of fibronectin splicing variants in organ transplantation: A differential pattern between rat cardiac allografts and isografts

American Journal of Pathology
1997 | Journal article
EID:

2-s2.0-0030988946

Contributors: Coito, A.J.; Brown, L.F.; Peters, J.H.; Kupiec-Weglinski, J.W.; Van De Water, L.
Source: Self-asserted source
Livingston Van De Water via Scopus - Elsevier

Extracellular matrix proteins and their interactions with the cellular repertoire of transplant recipients

Transplantation Proceedings
1997 | Journal article
EID:

2-s2.0-0030779883

Contributors: Kupiec-Weglinski, J.W.; Coito, A.J.; Van De Water, L.
Source: Self-asserted source
Livingston Van De Water via Scopus - Elsevier

Mechanisms by which fibrin and fibronectin appear in healing wounds: Implications for Peyronie's disease

Journal of Urology
1997 | Journal article
EID:

2-s2.0-0031060410

Contributors: Van De Water, L.
Source: Self-asserted source
Livingston Van De Water via Scopus - Elsevier

Role of endothelial selectins in wound repair

American Journal of Pathology
1997 | Journal article
EID:

2-s2.0-0030999872

Contributors: Subramaniam, M.; Saffaripour, S.; Van De Water, L.; Frenette, P.S.; Mayadas, T.N.; Hynes, R.O.; Wagner, D.D.
Source: Self-asserted source
Livingston Van De Water via Scopus - Elsevier

Anti-TNF-α treatment down-regulates the expression of fibronectin and decreases cellular infiltration of cardiac allografts in rats

Journal of Immunology
1995 | Journal article
EID:

2-s2.0-0028986028

Contributors: Coito, A.J.; Binder, J.; Brown, L.F.; De Sousa, M.; Van de Water, L.; Kupiec- Weglinski, J.W.
Source: Self-asserted source
Livingston Van De Water via Scopus - Elsevier

Balloon catheterization induces arterial expression of embryonic fibronectins

Arteriosclerosis, Thrombosis, and Vascular Biology
1995 | Journal article
EID:

2-s2.0-0028970944

Contributors: Dubin, D.; Peters, J.H.; Brown, L.F.; Logan, B.; Kent, K.C.; Berse, B.; Berven, S.; Cercek, B.; Sharifi, B.G.; Pratt, R.E. et al.
Source: Self-asserted source
Livingston Van De Water via Scopus - Elsevier

Keratinocyte-derived vascular permeability factor (vascular endothelial growth factor) is a potent mitogen for dermal microvascular endothelial cells

Journal of Investigative Dermatology
1995 | Journal article
EID:

2-s2.0-0029129814

Contributors: Detmar, M.; Yeo, K.-T.; Nagy, J.A.; Van de Water, L.; Brown, L.F.; Berse, B.; Elicker, B.M.; Ledbetter, S.; Dvorak, H.F.
Source: Self-asserted source
Livingston Van De Water via Scopus - Elsevier

Osteopontin at the Tumor/Host Interface: Functional Regulation by Thrombin‐Cleavage and Consequences for Cell Adhesion

Annals of the New York Academy of Sciences
1995 | Book
EID:

2-s2.0-0029085507

Contributors: Senger, D.R.; Brown, L.F.; Perruzzi, C.A.; Papadopoulos‐Sergiou, A.; Van De Water, L.
Source: Self-asserted source
Livingston Van De Water via Scopus - Elsevier

Overexpression of vascular permeability factor (VPF/VEGF) and its endothelial cell receptors in delayed hypersensitivity skin reactions

Journal of Immunology
1995 | Journal article
EID:

2-s2.0-0028959545

Contributors: Brown, L.F.; Olbricht, S.M.; Berse, B.; Jackman, R.W.; Matsueda, G.; Tognazzi, K.A.; Manseau, E.J.; Dvorak, H.F.; Van de Water, L.
Source: Self-asserted source
Livingston Van De Water via Scopus - Elsevier

TNF-α upregulates the expression of fibronectin in acutely rejecting rat cardiac allografts

Transplantation Proceedings
1995 | Journal article
EID:

2-s2.0-0028817455

Contributors: Coito, A.J.; Binder, J.; Brown, L.F.; De Sousa, M.; Van De Water, L.; Kupiec- Weglinski, J.W.
Source: Self-asserted source
Livingston Van De Water via Scopus - Elsevier

Vascular permeability factor/ vascular endothelial growth factor: An important mediator of angiogenesis in malignancy and inflammation

International Archives of Allergy and Immunology
1995 | Journal article
EID:

2-s2.0-0029047695

Contributors: Dvorak, H.F.; Detmar, M.; Claffey, K.P.; Nagy, J.A.; Van De Water, L.; Senger, D.R.
Source: Self-asserted source
Livingston Van De Water via Scopus - Elsevier

Adhesive properties of osteopontin: Regulation by a naturally occurring thrombin-cleavage in close proximity to the GRGDS cell-binding domain

Molecular Biology of the Cell
1994 | Journal article
EID:

2-s2.0-0028228866

Contributors: Senger, D.R.; Perruzzi, C.A.; Papadopoulos-Sergiou, A.; Van De Water, L.
Source: Self-asserted source
Livingston Van De Water via Scopus - Elsevier

Macrophages and fibroblasts express embryonic fibronectins during cutaneous wound healing

American Journal of Pathology
1993 | Journal article
EID:

2-s2.0-0027715980

Contributors: Brown, L.F.; Dubin, D.; Lavigne, L.; Logan, B.; Dvorak, H.F.; Van de Water, L.
Source: Self-asserted source
Livingston Van De Water via Scopus - Elsevier

Vascular permeability factor (VPF, VEGF) in tumor biology

Cancer and Metastasis Reviews
1993 | Journal article
EID:

2-s2.0-0027359953

Contributors: Senger, D.R.; Van De Water, L.; Brown, L.F.; Nagy, J.A.; Yeo, K.-T.; Yeo, T.-K.; Berse, B.; Jackman, R.W.; Dvorak, A.M.; Dvorak, H.F.
Source: Self-asserted source
Livingston Van De Water via Scopus - Elsevier

Expression and distribution of osteopontin in human tissues: Widespread association with luminal epithelial surfaces

Molecular Biology of the Cell
1992 | Journal article
EID:

2-s2.0-0027096666

Contributors: Brown, L.F.; Berse, B.; Van de Water, L.; Papadopoulos-Sergiou, A.; Perruzzi, C.A.; Manseau, E.J.; Dvorak, H.F.; Senger, D.R.
Source: Self-asserted source
Livingston Van De Water via Scopus - Elsevier
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