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Employment (2)

University of Southern California Keck School of Medicine: Los Angeles, CA, US

2020-07-01 to present | Associate Professor of Research (Department of Biochemistry and Molecular Medicine)
Employment
Source: Self-asserted source
Yifan Liu

University of Michigan: Ann Arbor, MI, US

2007 to 2020-06-30 | Research Assistant Professor (Department of Pathology)
Employment
Source: Self-asserted source
Yifan Liu

Education and qualifications (2)

Rockefeller University: New York, NY, US

2003 to 2007 | Postdoctoral fellow (Allis Lab)
Education
Source: Self-asserted source
Yifan Liu

University of Rochester: Rochester, NY, US

1997 to 2003 | Ph.D. (Department of Biology)
Education
Source: Self-asserted source
Yifan Liu

Works (35)

A Polycomb repressive complex is required for RNAi-mediated heterochromatin formation and dynamic distribution of nuclear bodies.

Nucleic acids research
2021-06-01 | Journal article
DOI: 10.1093/nar/gkaa1262
PMID: 33412588
PMC: PMC8191774
Source: Self-asserted source
Yifan Liu

Functional analysis of the methyltransferase SMYD in the single-cell model organism Tetrahymena thermophila

Marine Life Science & Technology
2020-05 | Journal article
DOI: 10.1007/s42995-019-00025-y
Part of ISSN: 2096-6490
Part of ISSN: 2662-1746
Source: Self-asserted source
Yifan Liu

A distinct class of eukaryotic MT-A70 methyltransferases maintain symmetric DNA N6-adenine methylation at the ApT dinucleotides as an epigenetic mark associated with transcription.

Nucleic acids research
2019-12-01 | Journal article
DOI: 10.1093/nar/gkz1053
PMID: 31722409
PMC: PMC7145601
Source: Self-asserted source
Yifan Liu

Transcription Regulation: Tales of a Divergent Mediator.

Current biology : CB
2019-07-01 | Journal article
DOI: 10.1016/j.cub.2019.06.033
PMID: 31336084
Source: Self-asserted source
Yifan Liu

Hidden genomic evolution in a morphospecies-The landscape of rapidly evolving genes in Tetrahymena.

PLoS biology
2019-06-03 | Journal article
DOI: 10.1371/journal.pbio.3000294
PMID: 31158217
PMC: PMC6564038
Source: Self-asserted source
Yifan Liu

RNAi-dependent <i>Polycomb</i> repression controls transposable elements in <i>Tetrahymena</i>.

Genes & development
2019-02-26 | Journal article
DOI: 10.1101/gad.320796.118
PMID: 30808657
PMC: PMC6411011
Source: Self-asserted source
Yifan Liu

Re-SET for Transcription.

Molecular cell
2018-06-01 | Journal article
DOI: 10.1016/j.molcel.2018.06.010
PMID: 29932907
Source: Self-asserted source
Yifan Liu

N6-adenine DNA methylation is associated with the linker DNA of H2A.Z-containing well-positioned nucleosomes in Pol II-transcribed genes in Tetrahymena.

Nucleic acids research
2017-11-01 | Journal article
DOI: 10.1093/nar/gkx883
PMID: 29036602
PMC: PMC5714169
Source: Self-asserted source
Yifan Liu

A germline-limited piggyBac transposase gene is required for precise excision in Tetrahymena genome rearrangement.

Nucleic acids research
2017-09-01 | Journal article
DOI: 10.1093/nar/gkx652
PMID: 28934495
PMC: PMC5766162
Source: Self-asserted source
Yifan Liu

Negative Regulators of an RNAi-Heterochromatin Positive Feedback Loop Safeguard Somatic Genome Integrity in Tetrahymena.

Cell reports
2017-03-01 | Journal article
DOI: 10.1016/j.celrep.2017.02.024
PMID: 28273462
PMC: PMC5357732
Source: Self-asserted source
Yifan Liu

N<sup>6</sup>-methyladenine DNA modification in the unicellular eukaryotic organism Tetrahymena thermophila.

European journal of protistology
2016-12-23 | Journal article
DOI: 10.1016/j.ejop.2016.12.003
PMID: 28135687
Source: Self-asserted source
Yifan Liu

Retrieving Quantitative Information of Histone PTMs by Mass Spectrometry.

Methods in enzymology
2016-12-07 | Journal article
DOI: 10.1016/bs.mie.2016.10.017
PMID: 28137562
Source: Self-asserted source
Yifan Liu

Histone methyltransferase TXR1 is required for both H3 and H3.3 lysine 27 methylation in the well-known ciliated protist Tetrahymena thermophila.

Science China. Life sciences
2016-10-17 | Journal article
DOI: 10.1007/s11427-016-0183-1
PMID: 27761696
Source: Self-asserted source
Yifan Liu

Enzymatic and chemical mapping of nucleosome distribution in purified micro- and macronuclei of the ciliated model organism, Tetrahymena thermophila.

Science China. Life sciences
2016-08-25 | Journal article
DOI: 10.1007/s11427-016-5102-x
PMID: 27568393
Source: Self-asserted source
Yifan Liu

Dissecting relative contributions of cis- and trans-determinants to nucleosome distribution by comparing Tetrahymena macronuclear and micronuclear chromatin.

Nucleic acids research
2016-08-03 | Journal article
DOI: 10.1093/nar/gkw684
PMID: 27488188
PMC: PMC5137421
Source: Self-asserted source
Yifan Liu

Methylation of histone H3K23 blocks DNA damage in pericentric heterochromatin during meiosis.

eLife
2014-08-26 | Journal article
DOI: 10.7554/elife.02996
PMID: 25161194
PMC: PMC4141274
Source: Self-asserted source
Yifan Liu

Bioinformatic and proteomic analysis of bulk histones reveals PTM crosstalk and chromatin features.

Journal of proteome research
2014-06-13 | Journal article
DOI: 10.1021/pr5001829
PMID: 24894457
PMC: PMC4096215
Source: Self-asserted source
Yifan Liu

Quantitative proteomics reveals histone modifications in crosstalk with H3 lysine 27 methylation.

Molecular & cellular proteomics : MCP
2014-01-01 | Journal article
DOI: 10.1074/mcp.m113.029025
PMID: 24382802
PMC: PMC3945906
Source: Self-asserted source
Yifan Liu

Impaired replication elongation in Tetrahymena mutants deficient in histone H3 Lys 27 monomethylation.

Genes & development
2013-07-24 | Journal article
DOI: 10.1101/gad.218966.113
PMID: 23884606
PMC: PMC3744725
Source: Self-asserted source
Yifan Liu

Quantification of histone modifications using ¹⁵N metabolic labeling.

Methods (San Diego, Calif.)
2013-02-27 | Journal article
DOI: 10.1016/j.ymeth.2013.02.004
PMID: 23454290
PMC: PMC3700598
Source: Self-asserted source
Yifan Liu

Quantitative proteomics reveals that the specific methyltransferases Txr1p and Ezl2p differentially affect the mono-, di- and trimethylation states of histone H3 lysine 27 (H3K27).

Molecular & cellular proteomics : MCP
2012-11-13 | Journal article
DOI: 10.1074/mcp.m112.021733
PMID: 23150054
PMC: PMC3675822
Source: Self-asserted source
Yifan Liu

Intercepting noncoding messages between germline and soma.

Genes & development
2012-08-01 | Journal article
DOI: 10.1101/gad.199992.112
PMID: 22895251
PMC: PMC3426757
Source: Self-asserted source
Yifan Liu

The nonhistone, N-terminal tail of an essential, chimeric H2A variant regulates mitotic H3-S10 dephosphorylation.

Genes & development
2012-03-01 | Journal article
DOI: 10.1101/gad.182683.111
PMID: 22426537
PMC: PMC3315122
Source: Self-asserted source
Yifan Liu

Gene network landscape of the ciliate Tetrahymena thermophila.

PloS one
2011-05-26 | Journal article
DOI: 10.1371/journal.pone.0020124
PMID: 21637855
PMC: PMC3102692
Source: Self-asserted source
Yifan Liu

An Ash2L/RbBP5 heterodimer stimulates the MLL1 methyltransferase activity through coordinated substrate interactions with the MLL1 SET domain.

PloS one
2010-11-23 | Journal article
DOI: 10.1371/journal.pone.0014102
PMID: 21124902
PMC: PMC2990719
Source: Self-asserted source
Yifan Liu

Dicer independent small RNAs associate with telomeric heterochromatin.

RNA (New York, N.Y.)
2009-05-21 | Journal article
DOI: 10.1261/rna.1423309
PMID: 19460867
PMC: PMC2704082
Source: Self-asserted source
Yifan Liu

Microarray analyses of gene expression during the Tetrahymena thermophila life cycle.

PloS one
2009-02-10 | Journal article
DOI: 10.1371/journal.pone.0004429
PMID: 19204800
PMC: PMC2636879
Source: Self-asserted source
Yifan Liu

Refined annotation and assembly of the Tetrahymena thermophila genome sequence through EST analysis, comparative genomic hybridization, and targeted gap closure.

BMC genomics
2008-11-26 | Journal article
DOI: 10.1186/1471-2164-9-562
PMID: 19036158
PMC: PMC2612030
Source: Self-asserted source
Yifan Liu

RNAi-dependent H3K27 methylation is required for heterochromatin formation and DNA elimination in Tetrahymena.

Genes & development
2007-06-01 | Journal article
DOI: 10.1101/gad.1544207
PMID: 17575054
PMC: PMC1891430
Source: Self-asserted source
Yifan Liu

Long-distance combinatorial linkage between methylation and acetylation on histone H3 N termini.

Proceedings of the National Academy of Sciences of the United States of America
2007-02-06 | Journal article
DOI: 10.1073/pnas.0610993104
PMID: 17284592
PMC: PMC1892956
Source: Self-asserted source
Yifan Liu

Deposition and function of histone H3 variants in Tetrahymena thermophila.

Molecular and cellular biology
2006-08-14 | Journal article
DOI: 10.1128/mcb.01139-06
PMID: 16908532
PMC: PMC1636873
Source: Self-asserted source
Yifan Liu

The H1 phosphorylation state regulates expression of CDC2 and other genes in response to starvation in Tetrahymena thermophila.

Molecular and cellular biology
2005-05-01 | Journal article
DOI: 10.1128/mcb.25.10.3914-3922.2005
PMID: 15870266
PMC: PMC1087734
Source: Self-asserted source
Yifan Liu

Elimination of foreign DNA during somatic differentiation in Tetrahymena thermophila shows position effect and is dosage dependent.

Eukaryotic cell
2005-02-01 | Journal article
DOI: 10.1128/ec.4.2.421-431.2005
PMID: 15701804
PMC: PMC549336
Source: Self-asserted source
Yifan Liu

Histone H3 lysine 9 methylation is required for DNA elimination in developing macronuclei in Tetrahymena.

Proceedings of the National Academy of Sciences of the United States of America
2004-01-30 | Journal article
DOI: 10.1073/pnas.0305421101
PMID: 14755052
PMC: PMC341817
Source: Self-asserted source
Yifan Liu

Phosphorylation and an ATP-dependent process increase the dynamic exchange of H1 in chromatin.

The Journal of cell biology
2002-09-01 | Journal article
DOI: 10.1083/jcb.200202131
PMID: 12356861
PMC: PMC2173238
Source: Self-asserted source
Yifan Liu

Peer review (2 reviews for 1 publication/grant)

Review activity for EMBO journal. (2)
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