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City of Hope Faculty Proile

Other IDs

Scopus Author ID: 57215597329
Scopus Author ID: 56135076500

Keywords

Stem cells in neurogenesis and neurological diseases, Stem cell biology, Regenerative medicine

Activities

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Employment (1)

Beckman Research Institute, City of Hope: Duarte, CA, US

Employment
Source: Self-asserted source
Yanhong Shi

Education and qualifications (2)

Salk Institute for Biological Studies: La Jolla, CA, US

Education
Source: Self-asserted source
Yanhong Shi

Northwestern University: Evanston, Illinois, US

Education
Source: Self-asserted source
Yanhong Shi

Works (50 of 71)

Items per page:
Page 1 of 2

Human iPSC-derived microglial cells protect neurons from neurodegeneration in long-term cultured adhesion brain organoids

Communications Biology
2025-01-09 | Journal article
DOI: 10.1038/s42003-024-07401-0
Contributors: Xianwei Chen; Guoqiang Sun; Lizhao Feng; E Tian; Yanhong Shi
Source: check_circle
Crossref

Microglial APOE3 Christchurch protects neurons from Tau pathology in a human iPSC-based model of Alzheimer’s disease

Cell Reports
2024-12 | Journal article
DOI: 10.1016/j.celrep.2024.114982
Contributors: Guoqiang George Sun; Cheng Wang; Randall C. Mazzarino; Paula Andrea Perez-Corredor; Hayk Davtyan; Mathew Blurton-Jones; Francisco Lopera; Joseph F. Arboleda-Velasquez; Yanhong Shi
Source: check_circle
Crossref

Induced pluripotent stem cells (iPSCs): molecular mechanisms of induction and applications

Signal Transduction and Targeted Therapy
2024-04-26 | Journal article
DOI: 10.1038/s41392-024-01809-0
Contributors: Jonas Cerneckis; Hongxia Cai; Yanhong Shi
Source: check_circle
Crossref

Modeling Sporadic Alzheimer's Disease in Human Brain Organoids under Serum Exposure

Advanced Science
2021-09 | Journal article
DOI: 10.1002/advs.202101462
Contributors: Xianwei Chen; Guoqiang Sun; E Tian; Mingzi Zhang; Hayk Davtyan; Thomas G. Beach; Eric M. Reiman; Mathew Blurton‐Jones; David M. Holtzman; Yanhong Shi
Source: check_circle
Crossref

Chlorotoxin-directed CAR T cells for specific and effective targeting of glioblastoma

Science translational medicine
2020 | Journal article
DOI: 10.1126/scitranslmed.aaw2672
EID:

2-s2.0-85081393844
Contributors: Wang, D.; Starr, R.; Chang, W.-C.; Aguilar, B.; Alizadeh, D.; Wright, S.L.; Yang, X.; Brito, A.; Sarkissian, A.; Ostberg, J.R. et al.
Source: Self-asserted source
Yanhong Shi via Scopus - Elsevier

Modeling Human Cytomegalovirus-Induced Microcephaly in Human iPSC-Derived Brain Organoids

Cell Reports Medicine
2020-03 | Journal article
DOI: 10.1016/j.xcrm.2020.100002
Part of ISSN: 2666-3791
Source: Self-asserted source
Yanhong Shi

Chlorotoxin Redirects Chimeric Antigen Receptor T Cells for Specific and Effective Targeting of Glioblastoma

bioRxiv
2020-01-25 | Preprint
DOI: 10.1101/2020.01.24.918888
Source: Self-asserted source
Yanhong Shi

Modeling microcephaly with cerebral organoids reveals a WDR62–CEP170–KIF2A pathway promoting cilium disassembly in neural progenitors

Nature Communications
2019 | Journal article
DOI: 10.1038/s41467-019-10497-2
EID:

2-s2.0-85067291861
Contributors: Zhang, W.; Yang, S.-L.; Yang, M.; Herrlinger, S.; Shao, Q.; Collar, J.L.; Fierro, E.; Shi, Y.; Liu, A.; Lu, H. et al.
Source: Self-asserted source
Yanhong Shi via Scopus - Elsevier

Treatment of canavan disease

2019-10-10 | Patent
PAT:

20190307808A1
Source: Self-asserted source
Yanhong Shi

Targeting glioblastoma stem cells through the tlx-tet3 axis

US Patent Office
2019-01-31 | Patent
PAT:

US 2019 / 0032055 A1
Source: Self-asserted source
Yanhong Shi

GFAP Mutations in Astrocytes Impair Oligodendrocyte Progenitor Proliferation and Myelination in an hiPSC Model of Alexander Disease

Cell Stem Cell
2018 | Journal article
DOI: 10.1016/j.stem.2018.07.009
EID:

2-s2.0-85050478274
Contributors: Li, L.; Tian, E.; Chen, X.; Chao, J.; Klein, J.; Qu, Q.; Sun, G.; Sun, G.; Huang, Y.; Warden, C.D. et al.
Source: Self-asserted source
Yanhong Shi via Scopus - Elsevier

Modeling neurological diseases using iPSC-derived neural cells: iPSC modeling of neurological diseases

Cell and Tissue Research
2018 | Journal article
DOI: 10.1007/s00441-017-2713-x
EID:

2-s2.0-85032513565
Contributors: Li, L.; Chao, J.; Shi, Y.
Source: Self-asserted source
Yanhong Shi via Scopus - Elsevier

The Anticancer Activity of a First-in-class Small-molecule Targeting PCNA

Clinical Cancer Research
2018 | Journal article
DOI: 10.1158/1078-0432.CCR-18-0592
EID:

2-s2.0-85057780234
Contributors: Gu, L.; Lingeman, R.; Yakushijin, F.; Sun, E.; Cui, Q.; Chao, J.; Hu, W.; Li, H.; Hickey, R.J.; Stark, J.M. et al.
Source: Self-asserted source
Yanhong Shi via Scopus - Elsevier

Enhancers of induced pluripotent stem cell reprogramming

US Patent Office
2018-04-24 | Patent
PAT:

9951316
Source: Self-asserted source
Yanhong Shi

Ablation of BAF170 in Developing and Postnatal Dentate Gyrus Affects Neural Stem Cell Proliferation, Differentiation, and Learning

Molecular Neurobiology
2017 | Journal article
DOI: 10.1007/s12035-016-9948-5
EID:

2-s2.0-84978173491
Contributors: Tuoc, T.; Dere, E.; Radyushkin, K.; Pham, L.; Nguyen, H.; Tonchev, A.B.; Sun, G.; Ronnenberg, A.; Shi, Y.; Staiger, J.F. et al.
Source: Self-asserted source
Yanhong Shi via Scopus - Elsevier

Induced pluripotent stem cell technology: A decade of progress

Nature Reviews Drug Discovery
2017 | Journal article
DOI: 10.1038/nrd.2016.245
EID:

2-s2.0-85006285022
Contributors: Shi, Y.; Inoue, H.; Wu, J.C.; Yamanaka, S.
Source: Self-asserted source
Yanhong Shi via Scopus - Elsevier

m<sup>6</sup>A RNA Methylation Regulates the Self-Renewal and Tumorigenesis of Glioblastoma Stem Cells

Cell Reports
2017 | Journal article
DOI: 10.1016/j.celrep.2017.02.059
EID:

2-s2.0-85015194429
Contributors: Cui, Q.; Shi, H.; Ye, P.; Li, L.; Qu, Q.; Sun, G.; Sun, G.; Lu, Z.; Huang, Y.; Yang, C.-G. et al.
Source: Self-asserted source
Yanhong Shi via Scopus - Elsevier

Nuclear Receptor TLX in Development and Diseases

Current Topics in Developmental Biology
2017 | Book chapter
DOI: 10.1016/bs.ctdb.2016.12.003
EID:

2-s2.0-85010941402
Contributors: Sun, G.; Cui, Q.; Shi, Y.
Source: Self-asserted source
Yanhong Shi via Scopus - Elsevier

Downregulation of TLX induces TET3 expression and inhibits glioblastoma stem cell self-renewal and tumorigenesis

Nature Communications
2016 | Journal article
DOI: 10.1038/ncomms10637
EID:

2-s2.0-84957546014
Contributors: Cui, Q.; Yang, S.; Ye, P.; Tian, E.; Sun, G.; Zhou, J.; Sun, G.; Liu, X.; Chen, C.; Murai, K. et al.
Source: Self-asserted source
Yanhong Shi via Scopus - Elsevier

Small-Molecule-Based Lineage Reprogramming Creates Functional Astrocytes

Cell Reports
2016 | Journal article
DOI: 10.1016/j.celrep.2016.06.042
EID:

2-s2.0-84989912774
Contributors: Tian, E.; Sun, G.; Sun, G.; Chao, J.; Ye, P.; Warden, C.; Riggs, A.D.; Shi, Y.
Source: Self-asserted source
Yanhong Shi via Scopus - Elsevier

The TLX-miR-219 cascade regulates neural stem cell proliferation in neurodevelopment and schizophrenia iPSC model

Nature Communications
2016 | Journal article
DOI: 10.1038/ncomms10965
EID:

2-s2.0-84961709637
Contributors: Murai, K.; Sun, G.; Ye, P.; Tian, E.; Yang, S.; Cui, Q.; Sun, G.; Trinh, D.; Sun, O.; Hong, T. et al.
Source: Self-asserted source
Yanhong Shi via Scopus - Elsevier

Differentially expressed microrna molecules for the treatment and diagnosis of cancer

2016-12-15 | Patent
PAT:

20160362689A1
Source: Self-asserted source
Yanhong Shi

Differentially expressed microRNA molecules for the treatment and diagnosis of cancer

US Patent Office
2016-04-19 | Patent
PAT:

9315809
Source: Self-asserted source
Yanhong Shi

Breast-cancer-secreted miR-122 reprograms glucose metabolism in premetastatic niche to promote metastasis

Nature Cell Biology
2015 | Journal article
DOI: 10.1038/ncb3094
EID:

2-s2.0-84923194150
Contributors: Fong, M.Y.; Zhou, W.; Liu, L.; Alontaga, A.Y.; Chandra, M.; Ashby, J.; Chow, A.; O'Connor, S.T.F.; Li, S.; Chin, A.R. et al.
Source: Self-asserted source
Yanhong Shi via Scopus - Elsevier

Enhancer analysis unveils genetic interactions between TLX and SOX2 in neural stem cells and in vivo reprogramming

Stem Cell Reports
2015 | Journal article
DOI: 10.1016/j.stemcr.2015.09.015
EID:

2-s2.0-84946738385
Contributors: Islam, M.M.; Smith, D.K.; Niu, W.; Fang, S.; Iqbal, N.; Sun, G.; Shi, Y.; Zhang, C.-L.
Source: Self-asserted source
Yanhong Shi via Scopus - Elsevier

MicroRNAs: Small molecules with big roles in neurodevelopment and diseases

Experimental Neurology
2015 | Journal article
DOI: 10.1016/j.expneurol.2014.08.005
EID:

2-s2.0-84930652644
Contributors: Sun, E.; Shi, Y.
Source: Self-asserted source
Yanhong Shi via Scopus - Elsevier

Direct Reprogramming Facilitated by Small Molecules

Journal of Stem Cell and Transplantation Biology
2015-05-22 | Journal article
DOI: 10.19104/jstb.2015.103
Part of ISSN: 2469-5157
Source: Self-asserted source
Yanhong Shi

142. Evolution of Cell-Specific RNA Aptamers Against Glioblastoma Cancer Stem Cells Via Live Cell-Based SELEX

Molecular Therapy
2015-05-01 | Journal article
DOI: 10.1016/s1525-0016(16)33747-9
Part of ISSN: 1525-0016
Source: Self-asserted source
Yanhong Shi

Enhancers of induced pluripotent stem cell reprogramming

2015-02-24 | Patent
PAT:

USOO8962322B2
Source: Self-asserted source
Yanhong Shi

Adaptive amphiphilic dendrimer-based nanoassemblies as robust and versatile siRNA delivery systems

Angewandte Chemie - International Edition
2014 | Journal article
DOI: 10.1002/anie.201406764
EID:

2-s2.0-84919388693
Contributors: Liu, X.; Zhou, J.; Yu, T.; Chen, C.; Cheng, Q.; Sengupta, K.; Huang, Y.; Li, H.; Liu, C.; Wang, Y. et al.
Source: Self-asserted source
Yanhong Shi via Scopus - Elsevier

Nuclear receptor TLX stimulates hippocampal neurogenesis and enhances learning and memory in a transgenic mouse model

Proceedings of the National Academy of Sciences of the United States of America
2014 | Journal article
DOI: 10.1073/pnas.1406779111
EID:

2-s2.0-84903445816
Contributors: Murai, K.; Qu, Q.; Sun, G.; Ye, P.; Li, W.; Asuelime, G.; Sun, E.; Tsai, G.E.; Shi, Y.
Source: Self-asserted source
Yanhong Shi via Scopus - Elsevier

MicroRNA let-7d regulates the TLX/microRNA-9 cascade to control neural cell fate and neurogenesis

Scientific Reports
2013 | Journal article
DOI: 10.1038/srep01329
EID:

2-s2.0-84880917178
Contributors: Zhao, C.; Sun, G.; Ye, P.; Li, S.; Shi, Y.
Source: Self-asserted source
Yanhong Shi via Scopus - Elsevier

Tet1 regulates adult hippocampal neurogenesis and cognition

Cell Stem Cell
2013 | Journal article
DOI: 10.1016/j.stem.2013.05.006
EID:

2-s2.0-84881178902
Contributors: Zhang, R.-R.; Cui, Q.-Y.; Murai, K.; Lim, Y.C.; Smith, Z.D.; Jin, S.; Ye, P.; Rosa, L.; Lee, Y.K.; Wu, H.-P. et al.
Source: Self-asserted source
Yanhong Shi via Scopus - Elsevier

Wnt7a Regulates Multiple Steps of Neurogenesis

Molecular and Cellular Biology
2013 | Journal article
DOI: 10.1128/MCB.00325-13
EID:

2-s2.0-84880682287
Contributors: Qu, Q.; Sun, G.; Murai, K.; Ye, P.; Li, W.; Asuelime, G.; Cheung, Y.-T.; Shi, Y.
Source: Self-asserted source
Yanhong Shi via Scopus - Elsevier

A case of cellular alchemy: Lineage reprogramming and its potential in regenerative medicine

Journal of Molecular Cell Biology
2012 | Journal article
DOI: 10.1093/jmcb/mjs005
EID:

2-s2.0-84864306472
Contributors: Asuelime, G.E.; Shi, Y.
Source: Self-asserted source
Yanhong Shi via Scopus - Elsevier

Characterization of TLX Expression in Neural Stem Cells and Progenitor Cells in Adult Brains

PLoS ONE
2012 | Journal article
DOI: 10.1371/journal.pone.0043324
EID:

2-s2.0-84865603437
Contributors: Li, S.; Sun, G.; Murai, K.; Ye, P.; Shi, Y.
Source: Self-asserted source
Yanhong Shi via Scopus - Elsevier

Dynamic roles of microRNAs in neurogenesis

Frontiers in Neuroscience
2012 | Journal article
DOI: 10.3389/fnins.2012.00071
EID:

2-s2.0-84862215678
Contributors: Lang, M.-F.; Shi, Y.
Source: Self-asserted source
Yanhong Shi via Scopus - Elsevier

Genome-wide profiling identified a set of miRNAs that are differentially expressed in glioblastoma stem cells and normal neural stem cells

PLoS ONE
2012 | Journal article
DOI: 10.1371/journal.pone.0036248
EID:

2-s2.0-84860448293
Contributors: Lang, M.-F.; Yang, S.; Zhao, C.; Sun, G.; Murai, K.; Wu, X.; Wang, J.; Gao, H.; Brown, C.E.; Liu, X. et al.
Source: Self-asserted source
Yanhong Shi via Scopus - Elsevier

Identification of Oct4-activating compounds that enhance reprogramming efficiency

Proceedings of the National Academy of Sciences of the United States of America
2012 | Journal article
DOI: 10.1073/pnas.1219181110
EID:

2-s2.0-84871385001
Contributors: Li, W.; Tian, E.; Chen, Z.-X.; Sun, G.; Ye, P.; Yang, S.; Lu, D.; Xie, J.; Ho, T.-V.; Tsark, W.M. et al.
Source: Self-asserted source
Yanhong Shi via Scopus - Elsevier

The little molecules that could: a story about microRNAs in neural stem cells and neurogenesis

Frontiers in Neuroscience
2012-12-07 | Journal article
DOI: 10.3389/fnins.2012.00176
Part of ISSN: 1662-453X
Source: Self-asserted source
Yanhong Shi

Histone deacetylases in neural stem cells and induced pluripotent stem cells

Journal of Biomedicine and Biotechnology
2011 | Journal article
DOI: 10.1155/2011/835968
EID:

2-s2.0-80053519269
Contributors: Shi, Y.; Sun, G.; Fu, C.; Shen, C.
Source: Self-asserted source
Yanhong Shi via Scopus - Elsevier

MiR-137 forms a regulatory loop with nuclear receptor TLX and LSD1 in neural stem cells

Nature Communications
2011 | Journal article
DOI: 10.1038/ncomms1532
EID:

2-s2.0-82555196537
Contributors: Sun, G.; Ye, P.; Murai, K.; Lang, M.-F.; Li, S.; Zhang, H.; Li, W.; Fu, C.; Yin, J.; Wang, A. et al.
Source: Self-asserted source
Yanhong Shi via Scopus - Elsevier

Current Status of Induced Pluripotent Stem Cells

Tissue Engineering in Regenerative Medicine
2011-07-27 | Book chapter
DOI: 10.1007/978-1-61779-322-6_3
Part of ISBN: 9781617793219
Part of ISBN: 9781617793226
Source: Self-asserted source
Yanhong Shi

Histone demethylase LSD1 regulates neural stem cell proliferation

Molecular and Cellular Biology
2010 | Journal article
DOI: 10.1128/MCB.01116-09
EID:

2-s2.0-77950675541
Contributors: Sun, G.; Alzayady, K.; Stewart, R.; Ye, P.; Yang, S.; Li, W.; Shi, Y.
Source: Self-asserted source
Yanhong Shi via Scopus - Elsevier

MicroRNA let-7b regulates neural stem cell proliferation and differentiation by targeting nuclear receptor TLX signaling

Proceedings of the National Academy of Sciences of the United States of America
2010 | Journal article
DOI: 10.1073/pnas.0908750107
EID:

2-s2.0-76649088031
Contributors: Zhao, C.; Sun, G.; Li, S.; Lang, M.-F.; Yang, S.; Li, W.; Shia, Y.
Source: Self-asserted source
Yanhong Shi via Scopus - Elsevier

MicroRNA regulation of neural stem cells and neurogenesis

Journal of Neuroscience
2010 | Journal article
DOI: 10.1523/JNEUROSCI.4280-10.2010
EID:

2-s2.0-78149478782
Contributors: Shi, Y.; Zhao, X.; Hsieh, J.; Wichterle, H.; Impey, S.; Banerjee, S.; Neveu, P.; Kosik, K.S.
Source: Self-asserted source
Yanhong Shi via Scopus - Elsevier

Nuclear receptors in stem cells and their therapeutic potential

Advanced Drug Delivery Reviews
2010 | Journal article
DOI: 10.1016/j.addr.2010.08.003
EID:

2-s2.0-78649319100
Contributors: Sun, G.; Shi, Y.
Source: Self-asserted source
Yanhong Shi via Scopus - Elsevier

Orphan nuclear receptor TLX activates Wnt/Β-catenin signalling to stimulate neural stem cell proliferation and self-renewal

Nature Cell Biology
2010 | Journal article
DOI: 10.1038/ncb2001
EID:

2-s2.0-78149302213
Contributors: Qu, Q.; Sun, G.; Li, W.; Yang, S.; Ye, P.; Zhao, C.; Yu, R.T.; Gage, F.H.; Evans, R.M.; Shi, Y.
Source: Self-asserted source
Yanhong Shi via Scopus - Elsevier

A feedback regulatory loop involving microRNA-9 and nuclear receptor TLX in neural stem cell fate determination

Nature Structural and Molecular Biology
2009 | Journal article
DOI: 10.1038/nsmb.1576
EID:

2-s2.0-64049095014
Contributors: Zhao, C.; Sun, G.; Li, S.; Shi, Y.
Source: Self-asserted source
Yanhong Shi via Scopus - Elsevier

Induced pluripotent stem cells, new tools for drug discovery and new hope for stem cell therapies

Current Molecular Pharmacology
2009 | Journal article
DOI: 10.2174/1874467210902010015
EID:

2-s2.0-77449141188
Contributors: Shi, Y.
Source: Self-asserted source
Yanhong Shi via Scopus - Elsevier
Items per page:
Page 1 of 2

Peer review (20 reviews for 13 publications/grants)

Review activity for Cell reports. (1)
Review activity for Cell stem cell. (1)
Review activity for Cell. (1)
Review activity for iScience. (2)
Review activity for Molecular psychiatry. (2)
Review activity for Nature (1)
Review activity for Nature communications (2)
Review activity for Nature microbiology. (1)
Review activity for Nature neuroscience. (1)
Review activity for Nature protocols (1)
Review activity for Neuron. (5)
Review activity for Trends in biochemical sciences. (1)
Review activity for Trends in molecular medicine. (1)
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