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Ciência ID: 0814-A87C-FF64

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Employment (1)

Instituto Português de Oncologia Francisco Gentil: Lisbon, Lisbon, PT

2004-07-01 to present | Técnico Superior (Molecular Pathobiology Research Unit (UIPM))
Employment
Source: Self-asserted source
Bruno Filipe

Funding (16)

Integrated approach to target early onset colorectal cancer: Validation of candidate biomarkers of metastatic early onset colorectal cancer for longitudinal disease monitoring

2023 to 2025 | Contract
Instituto Português de Oncologia de Lisboa Francisco Gentil EPE (Lisboa, PT)
GRANT_NUMBER:

UIC1169-B-IPO
Source: check_circle
CIÊNCIAVITAE

Voomics-Omics approaches to investigate the anticancer properties of colonic metabolites derived from Virgin Olive Oil

2021 to 2025 | Contract
Fundação para a Ciência e a Tecnologia (Lisboa, PT)
GRANT_NUMBER:

PTDC/BAA-AGR/4732/2021
Source: check_circle
CIÊNCIAVITAE

iNOVA4Health - Programa de Medicina Translacional (iBET, CEDOC/FCM, IPOLFG e ITQB)

2019-01-01 to 2019-12-31 | Contract
Fundação para a Ciência e a Tecnologia (Lisboa, PT)
GRANT_NUMBER:

UID/Multi/04462/2019
Source: check_circle
CIÊNCIAVITAE

Integrated approach to target early onset colorectal cancer: from familial risk evaluation to precision therapy

2018 to 2025 | Contract
Instituto Português de Oncologia de Lisboa Francisco Gentil EPE (Lisboa, PT)
GRANT_NUMBER:

UIC1169-FAI2017
Source: check_circle
CIÊNCIAVITAE

New genetic variants causing increased cancer risk with impact in diagnosis and treatment (Programme 2), colorectal cancer subdivision

2018 to 2023 | Contract
Fundação para a Ciência e a Tecnologia (Lisboa, PT)
GRANT_NUMBER:

UIDB/04462/2020
Source: check_circle
CIÊNCIAVITAE

Integrated approach to target early onset colorectal cancer: from familial risk evaluation to precision therapy

2018 to 2022 | Contract
Sociedade Portuguesa de Gastrenterologia (Lisboa, PT)
GRANT_NUMBER:

UIC1169-SPG2018
Source: check_circle
CIÊNCIAVITAE

Voomics -Omics approaches to investigate the anticancer propertiesof colonic metabolites derived from Virgin Olive Oil

2018 to 2021 | Contract
Instituto de Biologia Experimental e Tecnológica (Oeiras, PT)
GRANT_NUMBER:

UIC-IBETX
Source: check_circle
CIÊNCIAVITAE

Molecular profiling and development of novel therapies to target mutated genes in aggressive thyroid and colorectal cancers

2016 to 2021 | Contract
Fundação para a Ciência e a Tecnologia (Lisboa, PT)
GRANT_NUMBER:

UIC1022
Source: check_circle
CIÊNCIAVITAE

Colorectal Carcinogenesis Pathways-Establishing a link between carcinogenesis & therapeutic response

2016 to 2018 | Contract
Fundação para a Ciência e a Tecnologia (Lisboa, PT)
GRANT_NUMBER:

iNOVA4Health-2016-IRCB
Source: check_circle
CIÊNCIAVITAE

Molecular profiling and development of novel therapies to target mutated genes in aggressive thyroid and colorectal cancers

2016 to 2018 | Contract
Instituto Português de Oncologia de Lisboa Francisco Gentil EPE (Lisboa, PT)
GRANT_NUMBER:

UIC1022-FAI2015
Source: check_circle
CIÊNCIAVITAE

T2C-Development of a novel delivery system (DS) to target metastatic colorectal cancer (mCRC)

2015 to 2017 | Contract
Fundação para a Ciência e a Tecnologia (Lisboa, PT)
GRANT_NUMBER:

iNOVA4Health-2015-CD-CA
Source: check_circle
CIÊNCIAVITAE

Familial and individual cancer risk-identification of novel genes

2013 to 2018 | Contract
Instituto Português de Oncologia de Lisboa Francisco Gentil EPE (Lisboa, PT)
GRANT_NUMBER:

UIC829
Source: check_circle
CIÊNCIAVITAE

Identification of biomarkers of metastasis, predictive factors of response to therapy and new therapeutic targets in colon and rectal cancer: study of Wnt/b-catenin/TCF7L2 alterations

2013 to 2018 | Contract
Instituto Português de Oncologia de Lisboa Francisco Gentil EPE (Lisboa, PT)
GRANT_NUMBER:

IPO-2013-CA
Source: check_circle
CIÊNCIAVITAE

Study of the colonic distribution of APC monoallelic mutations in sporadic colorectal cancer patients

2012 to 2015 | Contract
Merck Serono Division Portugal (Algés, PT)
GRANT_NUMBER:

Merck-2012
Source: check_circle
CIÊNCIAVITAE

Mapeamento e identificação de genes envolvidos nos cancros da tiróide e do cólon e recto familiares

2006 to 2013 | Contract
Fundação Calouste Gulbenkian (Lisboa, PT)
GRANT_NUMBER:

FCG-2006
Source: check_circle
CIÊNCIAVITAE

Apoptose e resposta inflamatória na carcinogénese colorectal:interacção entre as vias do p53, APC/beta-catenina e TGF-beta no prognóstico e resistência

2004 to 2009 | Contract
Fundação Calouste Gulbenkian (Lisboa, PT)
GRANT_NUMBER:

FCG-2004
Source: check_circle
CIÊNCIAVITAE

Works (31)

Germline Variants in DNA Interstrand-Cross Link Repair Genes May Contribute to Increased Susceptibility for Serrated Polyposis Syndrome

International Journal of Molecular Sciences
2024-11 | Journal article | Author
DOI: 10.3390/ijms252111848
Contributors: Patrícia Silva; Inês Francisco; Bruno Filipe; PEDRO LAGE; Isadora Rosa; Sofia Fernandes; RICARDO FONSECA; Paula Campos Rodrigues Rodrigues; Joana Parreira; Isabel Claro et al.
Source: check_circle
Multidisciplinary Digital Publishing Institute

Diagnosis, follow up and clinical management of individuals identified with a TP53 pathogenic variant

Medical Research Archives
2022 | Journal article
DOI: 10.18103/mra.v10i7.2846
SOURCE-WORK-ID:

cv-prod-id-4157082

Part of ISSN: 2375-1916
Part of ISSN: 2375-1924
Contributors: Fernandes, Sofia; Fragoso, Sofia; Filipe, Bruno; Santos, Sidonia; Duarte, Teresa; Bento, Sandra; Mira, Beatriz; et al.
Source: check_circle
CIÊNCIAVITAE

Routine Immunohistochemical Analysis of Mismatch Repair Proteins in Colorectal Cancer—A Prospective Analysis

Cancers
2022-07-31 | Journal article
DOI: 10.3390/cancers14153730
SOURCE-WORK-ID:

cv-prod-id-4155847

Part of ISSN: 2072-6694
Contributors: Lemos Garcia, Joana; Rosa, Isadora; Saraiva, Sofia; Marques, Inês; Fonseca, Ricardo; Lage, Pedro; Francisco, Inês; et al.
Source: check_circle
CIÊNCIAVITAE

Patient-derived explants of colorectal cancer: histopathological and molecular analysis of long-term cultures

2021 | Journal article
DOI: 10.3390/cancers13184695
SOURCE-WORK-ID:

cv-prod-id-4155754

HANDLE: http://hdl.handle.net/10451/49661
OTHER-ID:

@article{http://hdl.handle.net/10451/49661,title = {Cancers},volume = {13},}

OTHER-ID:

Cancers (Basel). 2021 Sep 19;13(18):4695

Part of ISSN: 2072-6694
Contributors: da Mata, Sara; Franchi-Mendes, Teresa; Abreu, Sofia; Filipe, Bruno; Morgado, Sónia; Mesquita, Marta; Albuquerque, Cristina; et al.
Source: check_circle
CIÊNCIAVITAE

Pediatric Colorectal Cancer: A Heterogenous Entity

Journal of Pediatric Hematology/Oncology
2020-03 | Journal article
DOI: 10.1097/mph.0000000000001526
SOURCE-WORK-ID:

cv-prod-id-4155840

Part of ISSN: 1077-4114
Contributors: Cortez-Pinto, João; Claro, Isabel; Francisco, Inês; Lage, Pedro; Filipe, Bruno; Rodrigues, Paula; Chaves, Paula; Albuquerque, Cristina; Dias Pereira, António
Source: check_circle
CIÊNCIAVITAE

The nonsense mutation <i>MSH2</i> c.2152C&gt;T shows a founder effect in Portuguese Lynch syndrome families

Genes, Chromosomes and Cancer
2019-04-26 | Journal article
DOI: 10.1002/gcc.22759
SOURCE-WORK-ID:

cv-prod-id-4155857

Part of ISSN: 1045-2257
Part of ISSN: 1098-2264
Contributors: Pinheiro, Manuela; Francisco, Inês; Pinto, Carla; Peixoto, Ana; Veiga, Isabel; Filipe, Bruno; Santos, Catarina; et al.
Source: check_circle
CIÊNCIAVITAE

Patient-derived colorectal cancer explants - adequate models for chemotherapy testing?

Digestive Disease Week 2018
2018-06-02 | Conference poster
SOURCE-WORK-ID:

cv-prod-id-4159324
Contributors: Rosa, Isadora; Mata, Sara; Fonseca, Ricardo; Filipe, Bruno
Source: check_circle
CIÊNCIAVITAE

APC promoter 1B deletion deletion and monoallelic MUTYH mutation in a patient with adenomatous polyposis: report of a case

8 ESO-CNIO Conference on Familial Cancer 2018
2018-05-17 | Conference poster
SOURCE-WORK-ID:

cv-prod-id-4159990
Contributors: Filipe, Bruno
Source: check_circle
CIÊNCIAVITAE

Preservation of tumor architecture and heterogeneity in long-term cultures of patient-derived explants

Proceedings of the American Association for Cancer Research Annual Meeting 2018
2018-04-14 | Conference poster
SOURCE-WORK-ID:

cv-prod-id-4159904
Contributors: Abreu, Sofia; Silva, Fernanda; da Mata, Sara; Franchi-Mendes, Teresa; Teixeira, Marta; Filipe, Bruno
Source: check_circle
CIÊNCIAVITAE

Men seeking counselling in a Breast Cancer Risk Evaluation Clinic

ecancermedicalscience
2018-01-30 | Journal article
DOI: 10.3332/ecancer.2018.804
SOURCE-WORK-ID:

cv-prod-id-4155854

Part of ISSN: 1754-6605
Contributors: Freitas, Ana Catarina; Opinião, Ana; Fragoso, Sofia; Nunes, Hugo; Santos, Madalena; Clara, Ana; Bento, Sandra; et al.
Source: check_circle
CIÊNCIAVITAE

- GERMLINE VARIANTS IN DNA INTERSTRAND-CROSS LINK REPAIR GENES MAY CONTRIBUTE TO INCREASED SUSCEPTIBILITY FOR SERRATED POLYPOSIS

7th Biennial Meeting-InSIGHT- International Society for Gastrointestinal Hereditary Tumours
2017-07-05 | Conference poster
SOURCE-WORK-ID:

cv-prod-id-4159379
Contributors: Silva, Patrícia; Francisco, Inês; Filipe, Bruno
Source: check_circle
CIÊNCIAVITAE

CONTRIBUTION OF MUTYH GERMLINE MUTATIONS TO EARLY ONSET NON-POLYPOSIS COLORECTAL CANCER

7th Biennial Meeting-InSIGHT- International Society for Gastrointestinal Hereditary Tumours
2017-07-05 | Conference poster
SOURCE-WORK-ID:

cv-prod-id-4159537
Contributors: Filipe, Bruno
Source: check_circle
CIÊNCIAVITAE

GERMLINE VARIANTS IN HOMOLOGOUS RECOMBINATION (HR)-MEDIATED DNA DAMAGE REPAIR GENES MAY CONTRIBUTE TO INCREASED CRC SUSCEPTIBILITY IN FCCTX FAMILIES

7 th biennial meeting- InSIGHT- International Society for Gastrointestinal Hereditary Tumours
2017-07-05 | Conference poster
SOURCE-WORK-ID:

cv-prod-id-4158476
Contributors: Francisco, Inês; Magalhaes, Ana; Filipe, Bruno
Source: check_circle
CIÊNCIAVITAE

MICROSATELLITE INSTABILITY-LOW AND LOSS OF HETEROZIGOZITY IN 2P MAY UNDERLIE INCREASED SUSCEPTIBILITY FOR FAMILIAL RECTAL CANCER

7th Biennial Meeting-InSIGHT- International Society for Gastrointestinal Hereditary Tumours
2017-07-05 | Conference poster
SOURCE-WORK-ID:

cv-prod-id-4159606
Contributors: Albuquerque, Cristina; Duarte, Marlene; Silva, Patrícia; Filipe, Bruno
Source: check_circle
CIÊNCIAVITAE

THE MSH2 EXON 5 DELETION (C.792+8_943-450DEL) IS A FOUNDER MUTATION IN PORTUGUESE LYNCH SYNDROME FAMILIES WITH A CENTER-SOUTH ANCESTRY

7th Biennial Meeting-InSIGHT- International Society for Gastrointestinal Hereditary Tumours
2017-07-05 | Conference poster
SOURCE-WORK-ID:

cv-prod-id-4159521
Contributors: Francisco, Inês; Filipe, Bruno
Source: check_circle
CIÊNCIAVITAE

Serrated polyposis associated with a family history of colorectal cancer and/or polyps: The preferential location of polyps in the colon and rectum defines two molecular entities

International Journal of Molecular Medicine
2016-07-05 | Journal article
DOI: 10.3892/ijmm.2016.2666
SOURCE-WORK-ID:

cv-prod-id-4155878

Part of ISSN: 1107-3756
Part of ISSN: 1791-244X
Contributors: Silva, Patrícia; Albuquerque, Cristina; Lage, Pedro; Fontes, Vanessa; Fonseca, Ricardo; Vitoriano, Inês; Filipe, Bruno; et al.
Source: check_circle
CIÊNCIAVITAE

Contribution of MUTYH germline mutations to early onset non-polyposis colorectal cancer

ESO, CNIO and NRCO Conference on Familial Cancer 2016
2016-05-19 | Conference poster
SOURCE-WORK-ID:

cv-prod-id-4161221
Contributors: Filipe, Bruno
Source: check_circle
CIÊNCIAVITAE

Sporadic colorectal cancer: Studying ways to an end

United European Gastroenterology Journal
2016-04 | Journal article
DOI: 10.1177/2050640615599329
SOURCE-WORK-ID:

cv-prod-id-4155850

Part of ISSN: 2050-6406
Part of ISSN: 2050-6414
Contributors: Rosa, Isadora; Fidalgo, Paulo; Filipe, Bruno; Albuquerque, Cristina; Fonseca, Ricardo; Chaves, Paula; Pereira, António D
Source: check_circle
CIÊNCIAVITAE

Distinct spectrum of APC germline mutations in a Familial Adenomatous Polyposis population from the south of Portugal: Identification of a Mutational Hotspot and Suggestion of a Founder Mutation

6th ESO – CNIO Familial Cancer Conference 2014
2014-06-05 | Conference poster
SOURCE-WORK-ID:

cv-prod-id-4160036
Contributors: Filipe, Bruno
Source: check_circle
CIÊNCIAVITAE

Bethesda criteria for microsatellite instability testing: impact on the detection of new cases of Lynch syndrome

Familial Cancer
2012-07-10 | Journal article
DOI: 10.1007/s10689-012-9550-6
SOURCE-WORK-ID:

cv-prod-id-4155868

Part of ISSN: 1389-9600
Part of ISSN: 1573-7292
Contributors: Serrano, Miguel; Lage, Pedro; Belga, Sara; Filipe, Bruno; Francisco, Inês; Rodrigues, Paula; Fonseca, Ricardo; et al.
Source: check_circle
CIÊNCIAVITAE

Colorectal cancers show distinct mutation spectra in members of the canonical WNT signaling pathway according to their anatomical location and type of genetic instability

Genes, Chromosomes and Cancer
2010-05-07 | Journal article
DOI: 10.1002/gcc.20786
SOURCE-WORK-ID:

cv-prod-id-4155880

Part of ISSN: 1045-2257
Part of ISSN: 1098-2264
Contributors: Albuquerque, Cristina; Baltazar, Célia; Filipe, Bruno; Penha, Filipa; Pereira, Teresa; Smits, Ron; Cravo, Marília; et al.
Source: check_circle
CIÊNCIAVITAE

Carcinoma colorectal familiar de tipo X

2009 | Journal article
SOURCE-WORK-ID:

cv-prod-id-4155755

OTHER-ID:

http://www.scopus.com/inward/record.url?scp=70449725279&partnerID=8YFLogxK

OTHER-ID:

@article{http://www.scopus.com/inward/record.url?scp=70449725279&partnerID=8YFLogxK,title = {Acta Médica Portuguesa},volume = {22},}

Part of ISSN: 1646-0758
OTHER-ID:

PURE: 4445500
Contributors: Ferreira, Sara; Lage, Pedro; Sousa, Rita; Claro, Isabel; Francisco, Inês; Filipe, Bruno; Suspiro, Alexandra; et al.
Source: check_circle
CIÊNCIAVITAE

<i>APC</i> or <i>MUTYH</i> mutations account for the majority of clinically well-characterized families with FAP and AFAP phenotype and patients with more than 30 adenomas

Clinical Genetics
2009-09 | Journal article
DOI: 10.1111/j.1399-0004.2009.01241.x
SOURCE-WORK-ID:

cv-prod-id-4155892

Part of ISSN: 0009-9163
Part of ISSN: 1399-0004
Contributors: Filipe, B; Baltazar, C; Albuquerque, C; Fragoso, S; Lage, P; Vitoriano, I; Mão de Ferro, S; et al.
Source: check_circle
CIÊNCIAVITAE

APC Somatic Mosaicism in a Patient with Gardner Syndrome Carrying the E1573X Mutation: Report of a Case

Diseases of the Colon &amp; Rectum
2009-08 | Journal article
DOI: 10.1007/dcr.0b013e3181ab810f
SOURCE-WORK-ID:

cv-prod-id-4155881

Part of ISSN: 0012-3706
Contributors: Filipe, Bruno; Albuquerque, Cristina; Bik, Elsa; Lage, Pedro; Rodrigues, Paula; Vossen, Rolf; Tops, Carli; Nobre Leitão, Carlos
Source: check_circle
CIÊNCIAVITAE

[Familial colorectal cancer type X: clinical, pathological and molecular characterization]

Acta Med Port
2009-07-15 | Journal article
SOURCE-WORK-ID:

cv-prod-id-4158200
Contributors: Ferreira, Sara; Autor correspondente: Ferreira, Sara.
Source: check_circle
CIÊNCIAVITAE

Colorectal Adenomas in Young Patients: Microsatellite Instability is not a Useful Marker to Detect New Cases of Lynch Syndrome

Diseases of the Colon &amp; Rectum
2008-06 | Journal article
DOI: 10.1007/s10350-008-9224-5
SOURCE-WORK-ID:

cv-prod-id-4155885

Part of ISSN: 0012-3706
Contributors: Ferreira, Sara; Claro, Isabel; Lage, Pedro; Filipe, Bruno; Fonseca, Ricardo; Sousa, Rita; Francisco, Inês; et al.
Source: check_circle
CIÊNCIAVITAE

Carcinoma do cólon ou recto em jovens: caracterização clínico-patológica e vias de carcinogénese

2007 | Journal article
SOURCE-WORK-ID:

cv-prod-id-4155652

OTHER-ID:

http://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-81782007000200002
Contributors: Claro,I.; Ferreira,S.; Lage,P.; Salazar,M.; Francisco,I.; Filipe,B.; Albuquerque,C.; et al.
Source: check_circle
CIÊNCIAVITAE

Need of new clinical criteria for the identification of genetic Lynch syndrome

Acta Med Port
2007-02-13 | Journal article
SOURCE-WORK-ID:

cv-prod-id-4157925
Contributors: Rita Gomes de Sousa; Autor correspondente: Rita Gomes de Sousa.
Source: check_circle
CIÊNCIAVITAE

Diagnóstico genético na síndroma de Lynch: implicações da localização de mutações germinais em genes de reparação do ADN

2006 | Journal article
SOURCE-WORK-ID:

cv-prod-id-4155651

OTHER-ID:

http://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-81782006000200003
Contributors: Ferreira,S.; Claro,I.; Francisco,I.; Sousa,R.; Lage,P.; Albuquerque,C.; Filipe,B.; et al.
Source: check_circle
CIÊNCIAVITAE

Programa de vigilância em famílias com Síndroma de Lynch: a eficácia da medicina preventiva

2006 | Journal article
SOURCE-WORK-ID:

cv-prod-id-4155653

OTHER-ID:

http://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-81782006000600002
Contributors: Mão de Ferro,S.; Lage,P.; Suspiro,A.; Pereira da Silva,J.; Claro,I.; Fidalgo,P.; Rodrigues,P.; et al.
Source: check_circle
CIÊNCIAVITAE

HNPCC With Endometrial Cancer In Portuguese Families Raises The Probability of Finding Pathogenic Mutations in Mismatch Repair Genes Mainly in MSH2 Gene

XIII Porto Cancer Meeting on Mismatch repair genes, Microssatellite instability and Cancer 2004
2004-05-03 | Conference poster
SOURCE-WORK-ID:

cv-prod-id-4161237
Contributors: Filipe, Bruno
Source: check_circle
CIÊNCIAVITAE
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