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Works (3)

Antigen receptor stimulation drives selection against pathogenic mtDNA variants that dysregulate lymphocyte responses

2021-10-07 | Other
DOI: 10.1101/2021.10.05.21264464
Contributors: Jingdian Zhang; Camilla Koolmeister; Jinming Han; Roberta Filograna; Leo Hanke; Monika Àdori; Daniel J. Sheward; Sina Teifel; Yong Liu; Robert A. Harris et al.
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Mitochondrial dysfunction in adult midbrain dopamine neurons triggers an early immune response

PLOS Genetics
2021-09-27 | Journal article
DOI: 10.1371/journal.pgen.1009822
Contributors: Roberta Filograna; Rudolf J. Wiesner; Seungmin Lee; Katarína Tiklová; Mara Mennuni; Viktor Jonsson; Markus Ringnér; Linda Gillberg; Elena Sopova; Oleg Shupliakov et al.
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Modulation of mtDNA copy number ameliorates the pathological consequences of a heteroplasmic mtDNA mutation in the mouse

Science Advances
2019-04-05 | Journal article
DOI: 10.1126/sciadv.aav9824
Contributors: R. Filograna; C. Koolmeister; M. Upadhyay; A. Pajak; P. Clemente; R. Wibom; M. L. Simard; A. Wredenberg; C. Freyer; J. B. Stewart et al.
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